The seven faces of SIRT7

Mitochondria: In Sickness and in Health

Nunnari, J., & Suomalainen, A. (2012) · Cell · doi:10.1016/j.cell.2012.02.035 · Cited by 3,479

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

Michishita, E., Park, J. Y., Burneskis, J. M., Barrett, J. C., & Horikawa, I. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0033 · Cited by 1,364

Nucleolar proteome dynamics

Andersen, J., Lam, Y. W., Leung, A. K. L., Ong, S., Lyon, C. E., Lamond, A. I., & Mann, M. (2005) · Nature · doi:10.1038/nature03207 · Cited by 1,173

The nucleolus under stress

Boulon, S., Westman, B. J., Hutten, S., Boisvert, F.-M., & Lamond, A. I. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.024 · Cited by 1,103

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

Vakhrusheva, O., Smolka, C., Gajawada, P., Sawa Kostin, D., Boettger, T., Kubin, T., Braun, T. W., & Bober, E. (2008) · Circulation Research · doi:10.1161/circresaha.107.164558 · Cited by 646

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

Barber, M. F., Michishita-Kioi, E., Xi, Y., Tasselli, L., Kioi, M., Moqtaderi, Z., Tennen, R. I., Paredes, S., Young, N. L., Chen, K., et al. (2012) · Nature · doi:10.1038/nature11043 · Cited by 635

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

Ford, E., Voit, R., Liszt, G., Magin, C., Grummt, I., & Guarente, L. (2006) · Genes & Development · doi:10.1101/gad.1399706 · Cited by 629

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

Seligson, D. B., Horvath, S., McBrian, M. A., Mah, V. H., Yu, H., Tze, S., Wang, Q., Chia, D., Goodglick, L., & Kurdistani, S. K. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.080874 · Cited by 524

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

Watkins, N. J., & Bohnsack, M. T. (2011) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.117 · Cited by 520

NAD+ metabolism, stemness, the immune response, and cancer

Navas, L. E., & Carnero, A. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00354-w · Cited by 551

Nuclear sirtuins and inflammatory signaling pathways

Mendes, K. L., Lelis, D. D. F., & Santos, S. H. S. (2017) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2017.11.001 · Cited by 239

Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

Carafa, V., Altucci, L., & Nebbioso, A. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00038 · Cited by 186

The Roles of Sirtuin Family Proteins in Cancer Progression

Zhao, E., Hou, J., Ke, X., Abbas, M. N., Kausar, S., Zhang, L., & Cui, H. (2019) · Cancers · doi:10.3390/cancers11121949 · Cited by 125

Sirtuins' control of autophagy and mitophagy in cancer

Aventaggiato, M., Vernucci, E., Barreca, F., Russo, M. A., & Tafani, M. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107748 · Cited by 103

Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis

Yan, W., Liang, Y., Zhang, Q., Wang, D., Lei, M., Qu, J., He, X., Lei, Q., & Wang, Y. (2018) · EMBO Reports · doi:10.15252/embr.201846377 · Cited by 90

SIRT7 in the aging process

Lagunas‐Rangel, F. A. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04342-x · Cited by 90

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration

Tang, X., Li, G., Su, F., Cai, Y., Shi, L., Meng, Y., Liu, Z., Sun, J., Wang, M., Qian, M., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa039 · Cited by 91

Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7

Wu, D., Li, Y., Zhu, K. S., Wang, H., & Zhu, W. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00652 · Cited by 90

Subcellular compartmentalization of NAD+ and its role in cancer: A sereNADe of metabolic melodies

Zhu, Y., Liu, J., Park, J., Rai, P., & Zhai, R. G. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.04.002 · Cited by 82

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

Vazquez, B. N., Thackray, J. K., Simonet, N. G., Chahar, S., Kane-Goldsmith, N., Newkirk, S. J., Lee, S., Xing, J., Verzi, M. P., An, W., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz519 · Cited by 79

SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice

Guo, L., Tang, X., Zhang, S., Jin, M., Wang, M., Deng, Z., Liu, Z., Qian, M., Shi, W., Wang, Z., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2019104365 · Cited by 76

Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development

Hua, L., Yan, D., Wan, C., & Hu, B. (2022) · Cells · doi:10.3390/cells11193017 · Cited by 74

Sirtuins are crucial regulators of T cell metabolism and functions

Hamaidi, I., & Kim, S. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00739-7 · Cited by 70

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis

Jiang, L., Xiong, J., Zhan, J., Yuan, F., Tang, M., Zhang, C., Cao, Z., Chen, Y., Lu, X., Li, Y., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.780130 · Cited by 71

Histone Deacetylases and Their Inhibitors in Cancer Epigenetics

Hassell, K. N. (2019) · Diseases · doi:10.3390/diseases7040057 · Cited by 68

Mito-Nuclear Communication by Mitochondrial Metabolites and Its Regulation by B-Vitamins

Janssen, J. J. E., Grefte, S., Keijer, J., & de Boer, V. C. J. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00078 · Cited by 70

A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7

Wang, W., Angulo‐Ibáñez, M., Lyu, J., Kurra, Y., Tong, Z., Wu, B., Zhang, L., Sharma, V., Zhou, J., Lin, H., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b12083 · Cited by 63

SIRT7 Is a Prognostic Biomarker Associated With Immune Infiltration in Luminal Breast Cancer

Huo, Q., Li, Z., Cheng, L., Yang, F., & Xie, N. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00621 · Cited by 64

Exosomal miR‐130a‐3p regulates osteogenic differentiation of Human Adipose‐Derived stem cells through mediating SIRT7/Wnt/β‐catenin axis

Yang, S., Guo, S., Tong, S., & Sun, X. (2020) · Cell Proliferation · doi:10.1111/cpr.12890 · Cited by 62

Sirtuins and Immuno-Metabolism of Sepsis

Wang, X., Buechler, N. L., Woodruff, A. G., Long, D. L., Zabalawi, M., Yoza, B. K., McCall, C. E., & Vachharajani, V. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092738 · Cited by 59

Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis

Tang, X., Li, G., Shi, L., Su, F., Qian, M., Liu, Z., Meng, Y., Sun, S., Li, J., & Liu, B. (2021) · Nature Communications · doi:10.1038/s41467-021-25274-3 · Cited by 62

Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies

Sandonà, M., Cavioli, G., Renzini, A., Cedola, A., Gigli, G., Coletti, D., McKinsey, T. A., Moresi, V., & Saccone, V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054306 · Cited by 58

Stem cell‐intrinsic mechanisms regulating adult hair follicle homeostasis

Lee, S. A., Li, K. N., & Tumbar, T. (2020) · Experimental Dermatology · doi:10.1111/exd.14251 · Cited by 55

Targeting HDAC Complexes in Asthma and COPD

Zwinderman, M. R. H., de Weerd, S., & Dekker, F. J. (2019) · Epigenomes · doi:10.3390/epigenomes3030019 · Cited by 52

Targeting Sirtuins: Substrate Specificity and Inhibitor Design

Rajabi, N., Galleano, I., Madsen, A. S., & Olsen, C. A. (2018) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.11.003 · Cited by 52

Roles of sirtuin family members in chronic obstructive pulmonary disease

Zhang, X.-Y., Li, W., Zhang, J., Li, C., Zhang, J., & Lv, X. (2022) · Respiratory Research · doi:10.1186/s12931-022-01986-y · Cited by 50

MicroRNA-148b-3p is involved in regulating hypoxia/reoxygenation-induced injury of cardiomyocytes in vitro through modulating SIRT7/p53 signaling

Sun, M., Zhai, M., Zhang, N., Wang, R., Liang, H., Han, Q., Jia, Y., & Jiao, L. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.10.003 · Cited by 46

SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders

Kaiser, A., Schmidt, M., Huber, O., Frietsch, J. J., Scholl, S., Heidel, F. H., Hochhaus, A., Müller, J. P., & Ernst, T. (2020) · Leukemia · doi:10.1038/s41375-020-0803-3 · Cited by 48

Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7

Fan, X., Yan, K., Meng, Q., Sun, R., Yang, X., Yuan, D., Li, F., & Deng, H. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4173 · Cited by 42

Downregulation of circular RNA circPVT1 restricts cell growth of hepatocellular carcinoma through downregulation of Sirtuin 7 via microRNA‐3666

Li, Y., Shi, H., Yuan, J., Qiao, L., Dong, L., & Wang, Y. (2020) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13273 · Cited by 42

Social defeat stress in adult mice causes alterations in gene expression, alternative splicing, and the epigenetic landscape of H3K4me3 in the prefrontal cortex: An impact of early-life stress

Reshetnikov, V. V., Kisaretova, P. E., Ershov, N., Merkulova, T. I., & Bondar, N. P. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110068 · Cited by 42

SIRT7 Acts as a Guardian of Cellular Integrity by Controlling Nucleolar and Extra-Nucleolar Functions

Kumari, P., Tarighi, S., Braun, T. W., & Ianni, A. (2021) · Genes · doi:10.3390/genes12091361 · Cited by 40

Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity

Ruszkiewicz, J. A., Bürkle, A., & Mangerich, A. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102037 · Cited by 42

MicroRNA-340 inhibits the growth and invasion of angiosarcoma cells by targeting SIRT7

Wang, X., & Song, Y. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.04.148 · Cited by 38

Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity

Tinkov, A. A., Nguyen, T., Santamarı́a, A., Bowman, A. B., Djordjević, A. B., Paoliello, M. M. B., Skalny, A. V., & Aschner, M. (2021) · Archives of Toxicology · doi:10.1007/s00204-021-03048-6 · Cited by 38

RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression

Liu, X., Chen, J., Long, X., Lan, J., Liu, X., Zhou, M., Zhang, S., & Zhou, J. (2022) · Cell Death and Disease · doi:10.1038/s41419-021-04492-z · Cited by 34

Aging-Conferred SIRT7 Decline Inhibits Rosacea-Like Skin Inflammation by Modulating Toll-Like Receptor 2‒NF-κB Signaling

Li, G., Tang, X., Zhang, S., Deng, Z., Wang, B., Shi, W., Xie, H., Liu, B., & Li, J. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.03.026 · Cited by 33

SIRT7 Facilitates CENP-A Nucleosome Assembly and Suppresses Intestinal Tumorigenesis

Liu, X., Li, C., Li, Q., Chang, H.-C., & Tang, Y. (2020) · iScience · doi:10.1016/j.isci.2020.101461 · Cited by 33

Acetylation in Tumor Immune Evasion Regulation

Lu, J., He, X., Zhang, L., Zhang, R., & Li, W. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.771588 · Cited by 30

Upregulation of histone acetylation reverses organic anion transporter 2 repression and enhances 5-fluorouracil sensitivity in hepatocellular carcinoma

Wang, Y., Zhu, Q., Hu, H., Zhu, H., Yang, B., He, Q., Yu, L., & Zeng, S. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114546 · Cited by 29

Sirtuin 7 serves as a promising therapeutic target for cardiorenal diseases

Li, X., Zhang, Y.-P., Zhang, M.-W., Zhang, Z.-Z., & Zhong, J. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174977 · Cited by 28

Sirtuins in female meiosis and in reproductive longevity

Vázquez, B. N., Vaquero, A., & Schindler, K. (2020) · Molecular Reproduction and Development · doi:10.1002/mrd.23437 · Cited by 26

p53 inhibition attenuates cisplatin-induced acute kidney injury through microRNA-142-5p regulating SIRT7/NF-κB

Chen, G., Xue, H., Zhang, X., Ding, D., & Zhang, S. (2022) · Renal Failure · doi:10.1080/0886022x.2022.2039195 · Cited by 26

Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury

Sánchez‐Navarro, A., Martínez-Rojas, M. A., Albarrán‐Godínez, A., Pérez‐Villalva, R., Auwerx, J. H., de la Cruz, A., Noriega, L. G., Rosetti, F., & Bobadilla, N. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052573 · Cited by 26

Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma

Kim, Y., Jung, K., Kim, Y. H., Xu, P., Kang, B. E., Jo, Y., Pandit, N., Kwon, J., Gariani, K., Gariani, J., et al. (2024) · Drug Resistance Updates · doi:10.1016/j.drup.2024.101054 · Cited by 27

USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells

Su, Y., Wu, C., Chang, Y., Li, L., Chen, Y., Jia, X., Wang, X., Lv, Y. G., Yu, B., & Yuan, J. (2022) · Breast Cancer Research and Treatment · doi:10.1007/s10549-022-06711-3 · Cited by 25

Mammalian Sirtuins SIRT4 and SIRT7

Li, S., & Zheng, W. (2018) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.11.001 · Cited by 24

Exploring the Multi-Faceted Role of Sirtuins in Glioblastoma Pathogenesis and Targeting Options

Kunadis, E., & Piperi, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112889 · Cited by 23

Regulation of FKBP51 and FKBP52 functions by post-translational modifications

Daneri-Becerra, C., Zgajnar, N. R., Lotufo, C. M., Ramos-Hryb, A. B., Piwien‐Pilipuk, G., & Galigniana, M. D. (2019) · Biochemical Society Transactions · doi:10.1042/bst20190334 · Cited by 23

Suppression of microRNA-142-5p attenuates hypoxia-induced apoptosis through targeting SIRT7

Zhan, L., Lei, S., Li, W., Zhang, Y., Wang, H., Shi, Y., & Tian, Y. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.07.083 · Cited by 23

Akt-Dependent Glycolysis-Driven Lipogenesis Supports Proliferation and Survival of Human Pulmonary Arterial Smooth Muscle Cells in Pulmonary Hypertension

Jiang, L., Goncharov, D. A., Shen, Y., Lin, D., Chang, B., Pena, A. Z., DeLisser, H. M., Goncharova, E. A., & Kudryashova, T. V. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.886868 · Cited by 21

Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis

Zhang, K., Sowers, M. L., Cherryhomes, E., Singh, V. K., Mishra, A., Restrepo, B. I., Khan, A., & Jagannath, C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1121495 · Cited by 21

SIRT7 Downregulation Promotes Breast Cancer Metastasis Via LAP2α-Induced Chromosomal Instability

Huo, Q., Chen, S., Zhuang, J., Quan, C., Wang, Y., & Xie, N. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.75340 · Cited by 21

SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF

Kumari, P., Tarighi, S., Fuchshuber, E., Li, L., Fernández-Duran, I., Wang, M., Ayoson, J., Castelló-García, J. M., Gámez-García, A., Espinosa‐Alcantud, M., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2409269121 · Cited by 21

SIRT7 regulates the TGF-β1-induced proliferation and migration of mouse airway smooth muscle cells by modulating the expression of TGF-β receptor I

Fang, P., Xue, Y., Zhang, Y., Fan, N., Ou, L., Leng, L., Pan, J., & Wang, X. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.05.060 · Cited by 20

HIV-1 Vpr activates host CRL4-DCAF1 E3 ligase to degrade histone deacetylase SIRT7

Zhou, X., Monnie, C. M., DeLucia, M., & Ahn, J. (2021) · Virology Journal · doi:10.1186/s12985-021-01514-2 · Cited by 20

CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma

Zhang, C., Zhao, J., Zhao, J., Liu, B., Tang, W., Liu, Y., Huang, W., Weinman, S. A., & Li, Z. (2022) · Cancer Gene Therapy · doi:10.1038/s41417-022-00512-y · Cited by 21

Sirtuins and Gut Microbiota: Dynamics in Health and a Journey from Metabolic Dysfunction to Hepatocellular Carcinoma

Zhra, M., Elahi, M. A., Tariq, A., Abu‐Zaid, A., & Yaqinuddin, A. (2025) · Cells · doi:10.3390/cells14060466 · Cited by 18

SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice

Mizumoto, T., Yoshizawa, T., Sato, Y., Ito, T., Tsuyama, T., Satoh, A., Araki, S., Tsujita, K., Tamura, M., Oike, Y., et al. (2022) · Cells · doi:10.3390/cells11223609 · Cited by 18

Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance

Liao, Q., Zhu, C., Sun, X., Wang, Z., Chen, X., Deng, H., Tang, J., Jia, S., Liu, W., Xiao, W., et al. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105074 · Cited by 17

Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**

Bolding, J. E., Nielsen, A. L., Jensen, I., Hansen, T. N., Ryberg, L. A., Jameson, S. T., Harris, P., Peters, G. H. J., Denu, J. M., Rogers, J. M., et al. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202314597 · Cited by 17

The dark side of SIRT7

Lagunas‐Rangel, F. A. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04869-y · Cited by 17

Clinicopathological and molecular analysis of SIRT7 in hepatocellular carcinoma

Yanai, M., Kurata, M., Muto, Y., Iha, H., Kanao, T., Tatsuzawa, A., Ishibashi, S., Ikeda, M., Kitagawa, M., & Yamamoto, K. (2020) · Pathology · doi:10.1016/j.pathol.2020.03.011 · Cited by 15

Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases

Kreiner, G., Soenmez, A., Liss, B., & Parlato, R. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00106 · Cited by 15

The Role of NAD+, SIRTs Interactions in Stimulating and Counteracting Carcinogenesis

Podyacheva, E., & Toropova, Y. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097925 · Cited by 14

Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives

Ceballos, M. P., Quiroga, A. D., & Palma, N. F. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115573 · Cited by 14

Sirt7 inhibits Sirt1-mediated activation of Suv39h1

Kumari, P., Popescu, D., Yue, S., Bober, E., Ianni, A., & Braun, T. W. (2018) · Cell Cycle · doi:10.1080/15384101.2018.1486166 · Cited by 13

E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide

Lee, S. H., Lee, Y. J., Jung, S., & Chung, K. C. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.102909 · Cited by 12

Sirtuins as Therapeutic Targets for Treating Cancer, Metabolic Diseases, and Neurodegenerative Diseases

Akantibila, M., & Carabetta, V. J. (2025) · Pharmaceuticals · doi:10.3390/ph18111723 · Cited by 13

Unraveling the multifaceted role of SIRT7 and its therapeutic potential in human diseases

Han, L., Yuan, Z., Wu, J., Lu, J., Wang, Y., & Zhang, L. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135210 · Cited by 11

Impact of Vitamin D on Expression of SIRT7 and CYP24A1 in Human Breast Cancer Cells

Mojarad, M. A., Mojarad, M. A., & Noourbakhsh, M. (2022) · Research in Veterinary Science and Medicine · doi:10.25259/rvsm_6_2021 · Cited by 11

The role of B vitamins in protecting mitochondrial function

Mukherjee, S., Banerjee, O., & Singh, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90256-4.00001-1 · Cited by 11

SIRT7–SREBP1 restrains cancer cell metabolic reprogramming by upregulating IDH1

Su, F., Tang, X., Guo, L., Koeberle, A., & Liu, B. (2021) · Genome Instability & Disease · doi:10.1007/s42764-021-00031-4 · Cited by 11

Zebrafish sirt7 Negatively Regulates Antiviral Responses by Attenuating Phosphorylation of irf3 and irf7 Independent of Its Enzymatic Activity

Liao, Q., Ouyang, G., Zhu, J., Cai, X., Yu, G., Zhou, Z., Liu, X., Wang, J., & Xiao, W. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2100318 · Cited by 10

SIRT7 slows down stem cell aging by preserving heterochromatin: a perspective on the new discovery

Sun, L., & Dang, W. (2020) · Protein & Cell · doi:10.1007/s13238-020-00735-5 · Cited by 10

Mammalian Sirtuins and Their Relevance in Vascular Calcification

Pan, X., Pi, C., Ruan, X., Zheng, H., Zhang, D., & Liu, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.907835 · Cited by 9

Sirtuin insights: bridging the gap between cellular processes and therapeutic applications

Kamal, S., Babar, S., Ali, W., Rehman, K., Hussain, A., & Akash, M. S. H. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03263-9 · Cited by 8

SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosis

Li, F., Zhang, X., Xu, J., Zhang, Y., Li, G., Yang, X., Deng, G., Dai, Y., Liu, B., Kosan, C., et al. (2024) · mBio · doi:10.1128/mbio.00756-24 · Cited by 9

Sirtuins in Central Nervous System Tumors—Molecular Mechanisms and Therapeutic Targeting

Nowacka, A., Śniegocka, M., Śniegocki, M., & Ziółkowska, E. (2025) · Cells · doi:10.3390/cells14141113 · Cited by 8

Sirtuins in Parkinson's disease: Molecular mechanisms and pathophysiological roles

Li, X., Luo, X., Cao, X., Thomas, E. R., Wang, W., Zhou, X., Zhou, S., Wu, A., Gao, R., Liu, K., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102902 · Cited by 8

Genetic variations in the sheep SIRT7 gene and their correlation with body size traits

Xu, H., Zhang, X., Zang, R., Cai, Y., Cao, X., Yang, J., Li, J., Lan, X., & Wu, J. (2019) · Archives animal breeding/Archiv für Tierzucht · doi:10.5194/aab-62-189-2019 · Cited by 8

Multidrug resistance transporter-1 dysfunction perturbs meiosis and Ca2+ homeostasis in oocytes

Nabi, D., Bosi, D., Gupta, N., Thaker, N. A., Fissore, R. A., & Brayboy, L. M. (2022) · Reproduction · doi:10.1530/rep-22-0192 · Cited by 8

Beneficial effects of running and milk protein supplements on Sirtuins and risk factors of metabolic disorders in rats with low aerobic capacity

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Raising the list of SirT7 targets to a new level

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