Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies
Weaver, V.M., Petersen, O.W., Wang, F., Larabell, C.A., Briand, P., Damsky, C., Bissell, M.J.·1997·The Journal of Cell Biology
Cited by (1,000)
Items 101–200 of 1,000
- Hydrogel microenvironments for cancer spheroid growth and drug screeningYunfeng Li, Eugenia Kumacheva · 2018 · Science Advances
- Regulation of Tenascin-C, a Vascular Smooth Muscle Cell Survival Factor that Interacts with the αvβ3 Integrin to Promote Epidermal Growth Factor Receptor Phosphorylation and GrowthPeter Lloyd Jones, Julie A. Crack, Marlene Rabinovitch · 1997 · The Journal of Cell Biology
- Tumor Necrosis Factor-α Stimulates the Epithelial-to-Mesenchymal Transition of Human Colonic OrganoidsRichard C. Bates, Arthur M. Mercurio · 2003 · Molecular Biology of the Cell
- 3D cell culture opens new dimensions in cell-based assaysBradley A. Justice, Nadia A. Badr, Robin Allen Felder · 2008 · Drug Discovery Today
- Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic CarcinogenesisYasuyuki Mizutani, Hiroki Kobayashi, Tadashi Iida, Naoya Asai, Atsushi Masamune, Akitoshi Hara, Nobutoshi Esaki, Kaori Ushida, Shinji Mii, Yukihiro Shiraki et al. · 2019 · Cancer Research
- HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironmentBritta Weigelt, Alvin T. Lo, Catherine C. Park, Joe W. Gray, Mina J. Bissell · 2009 · Breast Cancer Research and Treatment
- The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerBritta Weigelt, Cyrus Michael Ghajar, Mina J. Bissell · 2014 · Advanced Drug Delivery Reviews
- The effect of matrix characteristics on fibroblast proliferation in 3D gelsKatrin Bott, Zee Upton, Karsten Schrobback, Martin Ehrbar, Jeffrey A. Hubbell, Matthias P. Lütolf, Simone C. Rizzi · 2010 · Biomaterials
- The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesisErik H.J. Danen, Petra Sonneveld, Cord Brakebusch, Reinhard Fässler, Arnoud Sonnenberg · 2002 · The Journal of Cell Biology
- Modeling dynamic reciprocity: Engineering three-dimensional culture models of breast architecture, function, and neoplastic transformationNelson, Celeste M., Bissell, Mina J. · 2005 · Seminars in Cancer Biology
- Microenvironmental regulation of cancer developmentHu, Min, Polyak, Kornelia · 2008 · Current Opinion in Genetics & Development
- Fibronectin and Its Integrin Receptors in CancerErkki I. Ruoslahti · 1999 · Advances in cancer research
- Tumor reversion: Correction of malignant behavior by microenvironmental cuesParaic A. Kenny, Mina J. Bissell · 2003 · International Journal of Cancer
- β1 Integrin Inhibitory Antibody Induces Apoptosis of Breast Cancer Cells, Inhibits Growth, and Distinguishes Malignant from Normal Phenotype in Three Dimensional Cultures and In vivoPark, Catherine C., Zhang, Hui, Pallavicini, Maria, Gray, Joe W., Baehner, Frederick, Park, Chong J., Bissell, Mina J. · 2006 · Cancer Research
- Stromal cells can contribute oncogenic signalsThea Dorothy Tlsty · 2001 · Seminars in Cancer Biology
- Metastasis prevention by targeting the dormant nicheCyrus Michael Ghajar · 2015 · Nature reviews. Cancer
- Mechanotransduction in tumor progression: The dark side of the forceBroders-Bondon, Florence, Nguyen Ho-Bouldoires, Thanh Huong, Fernandez-Sanchez, Maria-Elena, Farge, Emmanuel · 2018 · Journal of Cell Biology
- Three-dimensional context regulation of metastasisJanine Terra Erler, Valerie Marie Weaver · 2008 · Clinical & Experimental Metastasis
- Cancer cell angiogenic capability is regulated by 3D culture and integrin engagementClaudia Fischbach, Hyun Joon Kong, Susan X. Hsiong, Marta B. Evangelista, William W. Yuen, David J. Mooney · 2009 · Proceedings of the National Academy of Sciences
- Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesisLaura Kass, Janine Terra Erler, Micah Dembo, Valerie Marie Weaver · 2007 · The International Journal of Biochemistry & Cell Biology
- Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agentsTao Lin Sun, Simon J. Jackson, John W. Haycock, Sheila MacNeil · 2006 · Journal of Biotechnology
- Stromal Cells in the Tumor MicroenvironmentAlice E. Denton, Edward W. Roberts, Douglas T. Fearon · 2018 · Advances in experimental medicine and biology
- Signal co-operation between integrins and other receptor systemsCharles H. Streuli, Nasreen Akhtar · 2009 · Biochemical Journal
- Microenvironmental Regulators of Tissue Structure and Function Also Regulate Tumor Induction and Progression: The Role of Extracellular Matrix and Its Degrading EnzymesMina J. Bissell, Paraic A. Kenny, Derek C. Radisky · 2005 · Cold Spring Harbor Symposia on Quantitative Biology
- Can cancer be reversed by engineering the tumor microenvironment?Donald E. Ingber · 2008 · Seminars in Cancer Biology
- The somatic mutation theory of cancer: growing problems with the paradigm?Ana Maria Soto, Carlos Sonnenschein · 2004 · BioEssays
- Cancer and aging: a model for the cancer promoting effects of the aging stromaKrtolica, Ana, Campisi, Judith · 2002 · The International Journal of Biochemistry & Cell Biology
- Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentinNicola Xania West, Adrian Lussi, Joon Seong, Elmar Hellwig · 2012 · Clinical Oral Investigations
- Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubesTrietsch, Sebastiaan J., Naumovska, Elena, Kurek, Dorota, Setyawati, Meily C., Vormann, Marianne K., Wilschut, Karlijn J., Lanz, Henriëtte L., Nicolas, Arnaud, Ng, Chee Ping, Joore, Jos et al. · 2017 · Nature Communications
- Tumors and FibrinogenP. J. Simpson‐Haidaris, Brian J. Rybarczyk · 2001 · Annals of the New York Academy of Sciences
- Self-folding polymeric containers for encapsulation and delivery of drugsRohan Fernandes, David H. Gracias · 2012 · Advanced Drug Delivery Reviews
- Integrin-linked Protein Kinase Regulates Fibronectin Matrix Assembly, E-cadherin Expression, and TumorigenicityChuanyue Wu, Sarah Y. Keightley, Chungyee Leung-Hagesteijn, Galena Radeva, Marc G. Coppolino, Silvia M. Goicoechea, John A. McDonald, Shoukat Dedhar · 1998 · Journal of Biological Chemistry
- Advanced Cell Culture Techniques for Cancer Drug DiscoveryCarrie J. Lovitt, Todd Shelper, Vicky M. Avery · 2014 · Biology
- Beyond proteases: Basement membrane mechanics and cancer invasionJulie Chang, Ovijit Chaudhuri · 2019 · The Journal of Cell Biology
- The evolution of the cancer niche during multistage carcinogenesisMary Helen Barcellos‐Hoff, David C. Lyden, Timothy Cragin Wang · 2013 · Nature reviews. Cancer
- Cell polarity and cancer – cell and tissue polarity as a non-canonical tumor suppressorMinhui Lee, Valeri I. Vasioukhin · 2008 · Journal of Cell Science
- Unraveling the microenvironmental influences on the normal mammary gland and breast cancerBritta Weigelt, Mina J. Bissell · 2008 · Seminars in Cancer Biology
- Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compressionMonika E. Dolega, Morgan Delarue, François Ingremeau, Jacques Prost, Antoine Delon, Giovanni Cappello · 2017 · Nature Communications
- Phenotypic Reversion or Death of Cancer Cells by Altering Signaling Pathways in Three-Dimensional ContextsF. Wang, Rhonda K. Hansen, Derek C. Radisky, Toshiyuki Yoneda, Mary Helen Barcellos‐Hoff, OLE WILLIAM PETERSEN, Eva Ann Turley, Mina J. Bissell · 2002 · JNCI Journal of the National Cancer Institute
- Self-folding devices and materials for biomedical applicationsChristina L. Randall, Evin Gultepe, David H. Gracias · 2011 · Trends in biotechnology
- CD98hc (SLC3A2) mediates integrin signalingFeral, Chloe C., Nishiya, Naoyuki, Fenczik, Csilla A., Stuhlmann, Heidi, Slepak, Marina, Ginsberg, Mark H. · 2005 · Proceedings of the National Academy of Sciences
- Biological models and genes of tumor reversion: Cellular reprogramming through tpt1 /TCTP and SIAH-1Marcel Tuynder, Laurent Susini, Sylvie Prieur, Stéphanie Besse, Giusy Fiucci, Robert B. Amson, Adam Telerman · 2002 · Proceedings of the National Academy of Sciences
- The multicellular tumor spheroid model for high-throughput cancer drug discoveryDaniel V. LaBarbera, Brian G. Reid, Byong Hoon Yoo · 2012 · Expert Opinion on Drug Discovery
- Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?Giovanna Mazzoleni, Diego Di Lorenzo, Nathalie Steimberg · 2008 · Genes & Nutrition
- Targeting TACE-dependent EGFR ligand shedding in breast cancerParaic A. Kenny, Mina J. Bissell · 2007 · Journal of Clinical Investigation
- Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityMary Helen Barcellos‐Hoff, Antone L. Brooks · 2001 · Radiation Research
- The Inhibition of Tumor Cell Intravasation and Subsequent Metastasis via Regulation of In Vivo Tumor Cell Motility by the Tetraspanin CD151Andries Zijlstra, John D. Lewis, Bernard Degryse, Heidi Stuhlmann, James P. Quigley · 2008 · Cancer Cell
- Translationally controlled tumor protein is a target of tumor reversionMarcel Tuynder, Giusy Fiucci, Sylvie Prieur, Alexandra Lespagnol, Anne Géant, Séverine Beaucourt, Dominique Duflaut, Stéphanie Besse, Laurent Susini, J. Cavarelli et al. · 2004 · Proceedings of the National Academy of Sciences
- Architectural Transcription Factor HMGI(Y) Promotes Tumor Progression and Mesenchymal Transition of Human Epithelial CellsRaymond Reeves, Dale D. Edberg, Ying Li · 2001 · Molecular and Cellular Biology
- Modeling Ewing sarcoma tumors in vitro with 3D scaffoldsEliza Li Shan Fong, Salah-Eddine Lamhamedi-Cherradi, Emily Burdett, Vandhana Ramamoorthy, Alexander J. Lazar, F. Kurtis Kasper, Mary C. Farach‐Carson, Deeksha Vishwamitra, Elizabeth G. Demicco, Brian A. Menegaz et al. · 2013 · Proceedings of the National Academy of Sciences
- Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleusSophie A. Lelièvre, Valerie Marie Weaver, Jeffrey A. Nickerson, Larabell, C.A., Bhaumik, A., OLE WILLIAM PETERSEN, Mina J. Bissell · 1998 · eScholarship (California Digital Library)
- The current paradigm and challenges ahead for the dormancy of disseminated tumor cellsEmma Risson, Ana Rita Nobre, Véronique Maguer‐Satta, Julio A. Aguirre‐Ghiso · 2020 · Nature Cancer
- Mechanotransduction: use the force(s)Ewa K. Paluch, Celeste M. Nelson, Nicolas Biais, Ben Fabry, Jens Moeller, Beth L. Pruitt, Carina Wollnik, Galina Kudryasheva, Florian Rehfeldt, Walter Federle · 2015 · BMC Biology
- Mechanisms of Cancer Cell Dormancy—Another Hallmark of Cancer?Albert C. Yeh, Sridhar Ramaswamy · 2015 · Cancer Research
- Integrins as attractive targets for cancer therapeuticsMeng Li, Ying Wang, Mengwei Li, Xuezhen Wu, Sarra Setrerrahmane, Hanmei Xu · 2021 · Acta Pharmaceutica Sinica B
- Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivoJulio A. Aguirre Ghiso · 2002 · Oncogene
- Palmitoylation of Tetraspanin Proteins: Modulation of CD151 Lateral Interactions, Subcellular Distribution, and Integrin-dependent Cell MorphologyXiuwei H. Yang, Christoph Claas, Stine‐Kathrein Kraeft, Lan Bo Chen, Zemin Wang, Jordan A. Kreidberg, Martin E. Hemler · 2002 · Molecular Biology of the Cell
- Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challengeMaria Bokhari, Ross J. Carnachan, Neil R. Cameron, Stefan Alexander Przyborski · 2007 · Journal of Anatomy
- Increased β1 Integrin Is Associated with Decreased Survival in Invasive Breast CancerEvelyn S. Yao, Hui Zhang, Yunn‐Yi Chen, Brian Lee, Karen Chew, Dan A. Moore, Catherine Park · 2007 · Cancer Research
- Outgrowth of single oncogene-expressing cells from suppressive epithelial environmentsCheuk T. Leung, Joan S. Brugge · 2012 · Nature
- Stromagenesis: The changing face of fibroblastic microenvironments during tumor progressionDorothy A. Beacham, Edna Cukierman · 2005 · Seminars in Cancer Biology
- Emerging roles of exosomes during epithelial–mesenchymal transition and cancer progressionDavid W. Greening, Shashi K. Gopal, Rommel A. Mathias, Lin Liu, Jingyi Sheng, Hong‐Jian Zhu, Richard J. Simpson · 2015 · Seminars in Cell and Developmental Biology
- Reciprocal repression between P53 and TCTPRobert B. Amson, Salvatore Pece, Alexandra Lespagnol, Rajesh Vyas, Giovanni Mazzarol, Daniela Tosoni, Ivan Nicola Colaluca, Giuseppe Viale, Sylvie Rodrigues-Ferreira, Jessika Wynendaele et al. · 2011 · Nature Medicine
- Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cellsHong Shu Liu, Derek C. Radisky, Fei Wang, Mina J. Bissell · 2004 · The Journal of Cell Biology
- Enzymatic Noncovalent SynthesisHongjian He, Weiyi Tan, Jiaqi Guo, Meihui Yi, Adrianna N. Shy, Bing Xu · 2020 · Chemical Reviews
- β1 Integrin Inhibition Dramatically Enhances Radiotherapy Efficacy in Human Breast Cancer XenograftsPark, Catherine C., Zhang, Hui J., Yao, Evelyn S., Park, Chong J., Bissell, Mina J. · 2008 · Cancer Research
- Theories of carcinogenesis: An emerging perspectiveCarlos Sonnenschein, Ana Maria Soto · 2008 · Seminars in Cancer Biology
- Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progressionMichael K. Wendt, Maozhen Tian, William P. Schiemann · 2011 · Cell and Tissue Research
- The α2β1 integrin is a metastasis suppressor in mouse models and human cancerNorma E. Ramirez, Zhonghua Zhang, Aasakiran Madamanchi, Kelli Lynn Boyd, Lynda O’Rear, Abudi Nashabi, Zhengzi Li, William D. Dupont, Andries Zijlstra, Mary M. Zutter · 2010 · Journal of Clinical Investigation
- The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like ProtrusionsTsukasa Shibue, Mary W. Brooks, M. Fatih Inan, Ferenc Reinhardt, Robert A. Weinberg · 2012 · Cancer Discovery
- Three‐dimensional cell culture models for anticancer drug screening: Worth the effort?Verjans, Eddy‐Tim, Doijen, Jordi, Luyten, Walter, Landuyt, Bart, Schoofs, Liliane · 2018 · Journal of Cellular Physiology
- The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assayValerie Marie Weaver, M. J. Bissell, Andrew H. Fischer, O. W. Peterson · 1996 · Biochemistry and Cell Biology
- Chitosan–alginate 3D scaffolds as a mimic of the glioma tumor microenvironmentKievit, Forrest M., Florczyk, Stephen J., Leung, Matthew C., Veiseh, Omid, Park, James O., Disis, Mary L., Zhang, Miqin · 2010 · Biomaterials
- Integrins Play a Critical Role in Mechanical Stress–Induced p38 MAPK ActivationRyuichi Aikawa, Toshio Nagai, Sumiyo Kudoh, Yunzeng Zou, Mariko Hori Tanaka, Masahito Tamura, Hiroshi Akazawa, Hiroyuki Takano, Ryozo Nagai, Issei Komuro · 2002 · Hypertension
- Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathwaysYasuhito Onodera, Jin‐Min Nam, Mina J. Bissell · 2013 · Journal of Clinical Investigation
- The force awakens: metastatic dormant cancer cellsSo‐Yeon Park, Jeong‐Seok Nam · 2020 · Experimental & Molecular Medicine
- Cell-Matrix Interactions in Mammary Gland Development and Breast CancerJohn L. Muschler, Charles H. Streuli · 2010 · Cold Spring Harbor Perspectives in Biology
- Direct Cell Writing of 3D Microorgan for In Vitro Pharmacokinetic ModelRobert C. Chang, Jae Nam, Wei Sun · 2008 · Tissue Engineering Part C Methods
- Coherent angular motion in the establishment of multicellular architecture of glandular tissuesKandice Tanner, Hidetoshi Mori, Rana M Mroue, Alexandre Bruni‐Cardoso, Mina J. Bissell · 2012 · Proceedings of the National Academy of Sciences
- Extracellular Matrix Stiffness and Architecture Govern Intracellular Rheology in CancerErin L. Baker, Roger T. Bonnecaze, Muhammad Hamid Zaman · 2009 · Biophysical Journal
- Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2Hong Liu, Derek C. Radisky, Celeste M. Nelson, Hui Zhang, Jimmie E. Fata, Richard A. Roth, Mina J. Bissell · 2006 · Proceedings of the National Academy of Sciences
- The breast tumor microenvironment: role in cancer development, progression and response to therapySuruchi Mittal, Nicola Jane Brown, Ingunn Holen · 2018 · Expert Review of Molecular Diagnostics
- Spheroids and cell survivalRichard C. Bates · 2000 · Critical Reviews in Oncology/Hematology
- Regulation of Tumor Growth and Metastasis: The Role of Tumor MicroenvironmentHadi Alphonse Goubran, Rami R. Kotb, Julie Stakiw, Mohamed E. Emara, Thierry Burnouf · 2014 · Cancer Growth and Metastasis
- Monomethyl selenium-specific inhibition of MMP-2 and VEGF expression: Implications for angiogenic switch regulationCheng Jiang, Howard E. Ganther, Junxuan Lü · 2000 · Molecular Carcinogenesis
- A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasisNathan Edward Reticker-Flynn, David F. Braga Malta, Monte M. Winslow, John M. Lamar, Mary Jue Xu, Gregory H. Underhill, Richard O. Hynes, Tyler Jacks, Sangeeta N. Bhatia · 2012 · Nature Communications
- Fibronectin Expression Modulates Mammary Epithelial Cell Proliferation during Acinar DifferentiationCourtney M. Williams, Adam Jeffrey Engler, R. Daniel Slone, Leontine L. Galante, Jean E. Schwarzbauer · 2008 · Cancer Research
- Autocrine laminin-5 ligates α6β4 integrin and activates RAC and NFκB to mediate anchorage-independent survival of mammary tumorsNastaran Zahir, Johnathon N. Lakins, Alan John Russell, Wenyu Ming, Chandrima Chatterjee, Gabriela I. Rozenberg, M. Peter Marinkovich, Valerie Marie Weaver · 2003 · The Journal of Cell Biology
- 14-3-3ζ Cooperates with ErbB2 to Promote Ductal Carcinoma In Situ Progression to Invasive Breast Cancer by Inducing Epithelial-Mesenchymal TransitionJing Lü, Hua Guo, Warapen Treekitkarnmongkol, Ping Li, Jian Zhang, Bin Shi, Chen Ling, Xiaoyan Zhou, Tongzhen Chen, Paul J. Chiao et al. · 2009 · Cancer Cell
- Integrin signaling in epithelial cellsMichael Z. Gilcrease · 2006 · Cancer Letters
- Tumor cell invasiveness correlates with changes in integrin expression and localizationSabine Macho‐Maschler, Gerhard Wirl, Herbert Spring, Dorothea v Bredow, Isabelle Sordat, Hartmut Beug, Ernst Reichmann A · 2005 · Oncogene
- Microfluidic titer plate for stratified 3D cell cultureTrietsch, Sebastiaan J., Israëls, Guido D., Joore, Jos, Hankemeier, Thomas, Vulto, Paul · 2013 · Lab on a Chip
- The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell functionShelly R. Peyton, Cyrus Michael Ghajar, Chirag B. Khatiwala, Andrew J. Putnam · 2007 · Cell Biochemistry and Biophysics
- The molecular programme of tumour reversion: the steps beyond malignant transformationAdam Telerman, Robert B. Amson · 2009 · Nature reviews. Cancer
- Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinationsCharoen, Kristie M., Fallica, Brian, Colson, Yolonda L., Zaman, Muhammad H., Grinstaff, Mark W. · 2014 · Biomaterials
- Microfabrication of Three-Dimensional Engineered ScaffoldsJeffrey T. Borenstein, Eli J. Weinberg, Brian K. Orrick, Cathryn A. Sundback, Mohammad R. K. Mofrad, Joseph Phillip Vacanti · 2007 · Tissue Engineering
- Multiscale Modeling of Form and FunctionAdam Jeffrey Engler, Patrick Orson Humbert, Bernhard Wehrle‐Haller, Valerie Marie Weaver · 2009 · Science
- E-Cadherin Cell-Cell Adhesion in Ewing Tumor Cells Mediates Suppression of Anoikis through Activation of the ErbB4 Tyrosine KinaseHyung‐Gyoo Kang, Jasmine M. Jenabi, Jingsong Zhang, Nino Keshelava, Hiroyuki Shimada, William A. May, Tony Ng, C. Patrick Reynolds, Timothy Junius Triche, Poul H. B. Sorensen · 2007 · Cancer Research
- Dynamically tunable cell culture platforms for tissue engineering and mechanobiologyKoichiro Uto, Jonathan H. Tsui, Cole A. DeForest, Deok‐Ho Kim · 2016 · Progress in Polymer Science
- Cancer Stem Cells and Aneuploid Populations within Developing Tumors Are the Major Determinants of Tumor DormancyAnjali P. Kusumbe, Sharmila A. Bapat · 2009 · Cancer Research