CoChat
Sign Up
Cited by 422Chemokine receptors and signalingImmune cells in cancerImmune Response and Inflammation

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

Open access
Auffray, Cedric, Fogg, Darin K., Narni-Mancinelli, Emilie, Senechal, Brigitte, Trouillet, Celine, Saederup, Noah, Leemput, Julia, Bigot, Karine, Campisi, Laura, Abitbol, Marc, Molina, Thierry, Charo, Israel, Hume, David A., Cumano, Ana, Lauvau, Gregoire, Geissmann, Frederic·2009·Journal of Experimental Medicine
DOI 10.1084/jem.20081385PMC PMC2699130
Open this paper in CoChat — free accountOpen PDF

Abstract

CX3CR1 expression is associated with the commitment of CSF-1R+ myeloid precursors to the macrophage/dendritic cell (DC) lineage. However, the relationship of the CSF-1R+ CX3CR1+ macrophage/DC precursor (MDP) with other DC precursors and the role of CX3CR1 in macrophage and DC development remain unclear. We show that MDPs give rise to conventional DCs (cDCs), plasmacytoid DCs (PDCs), and monocytes, including Gr1+ inflammatory monocytes that differentiate into TipDCs during infection. CX3CR1 deficiency selectively impairs the recruitment of blood Gr1+ monocytes in the spleen after transfer and during acute Listeria monocytogenes infection but does not affect the development of monocytes, cDCs, and PDCs.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1084/jem.20081385

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 50 references

Cited by

Sorted by citations

Items 401–419 of 419

Related

See all

Metadata

Authors
Auffray, C., Fogg, D. K., Narni-Mancinelli, E., Senechal, B., Trouillet, C., Saederup, N., Leemput, J., Bigot, K., Campisi, L., Abitbol, M., Molina, T., Charo, I., Hume, D. A., Cumano, A., Lauvau, G., & Geissmann, F.
Affiliations
  • Laboratory of Biology of the Mononuclear Phagocyte System, Institut National de la Santé et de la Recherche Médicale (INSERM) U838, Université Paris-Descartes, 75015 Paris, France 1
  • Inserm (FR)
  • INSERM U924, Université de Nice-Sophia Antipolis, 06560 Valbonne, France 2
  • University of California, San Francisco (US)
  • Université Paris Descartes (FR)
  • Roslin Institute (GB)
ORCID
Venue
Journal of Experimental Medicine
Publisher
Rockefeller University Press
Published
2009-03-09
Volume
206
Issue
3
Pages
595-606
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
DOI
10.1084/jem.20081385
PMC
PMC2699130
OpenAlex
W2142750845
Cited by
422
References
50
Citations by year
2026: 4 · 2025: 7 · 2024: 14 · 2023: 17 · 2022: 16 · 2021: 21 · 2020: 17 · 2019: 26 · 2018: 21 · 2017: 28 · 2016: 32 · 2015: 24 · 2014: 33 · 2013: 43 · 2012: 36
FWCI
19.67
Type
journal article
Language
en
Open access
Locations
  • The Journal of Experimental Medicine (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
  • Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
  • HAL (submittedVersion, other-oa)
  • Research Portal (King's College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Chemokine receptors and signaling
  • Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
  • Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Keywords
CX3CR1, CSF1R, myeloid dendritic cells, plasmacytoid dendritic cells, monocytes, Listeria monocytogenes infection, monocyte recruitment, spleen, inflammation, myeloid development
MeSH terms
CX3C Chemokine Receptor 1, Animals, Bone Marrow Cells, Cell Differentiation, Cell Movement, Cell Survival, Dendritic Cells, Inflammation, Listeriosis, Listeria monocytogenes, Macrophages, Monocytes, Phenotype, Spleen, Stem Cells, Tumor Necrosis Factor-alpha, Receptor, Macrophage Colony-Stimulating Factor, Reactive Oxygen Species, Receptors, Chemokine, Cell Proliferation, Mice, fms-Like Tyrosine Kinase 3, Nitric Oxide Synthase Type II

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review