CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

Dendritic cells and the control of immunity

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Cx3cl1 (Fractalkine): A Signpost for Biliary Inflammation in Primary Biliary Cirrhosis

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CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3

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Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination

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Development and function of tissue resident macrophages in mice

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Lymphoid Tissue and Plasmacytoid Dendritic Cells and Macrophages Do Not Share a Common Macrophage-Dendritic Cell-Restricted Progenitor

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Transcriptional Control of Dendritic Cell Development

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Characterization of a Resident Population of Adventitial Macrophage Progenitor Cells in Postnatal Vasculature

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Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection

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Functional Phenotype of Synovial Monocytes Modulating Inflammatory T-Cell Responses in Rheumatoid Arthritis (RA)

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Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice

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Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression

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A role for spleen monocytes in post-ischemic brain inflammation and injury

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Monocyte-Mediated Immune Defense Against Murine Listeria monocytogenes Infection

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Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularization

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How dendritic cells shape atherosclerosis

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Mobilisation of the splenic monocyte reservoir and peripheral CX3CR1 deficiency adversely affects recovery from spinal cord injury

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Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells

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Phenotypic and functional alterations of monocyte subsets with aging

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Ly6Clow and Not Ly6Chigh Macrophages Accumulate First in the Heart in a Model of Murine Pressure-Overload

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Marrow-Derived Cells Regulate the Development of Early Diabetic Retinopathy and Tactile Allodynia in Mice

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Monocyte Subsets Are Differentially Lost from the Circulation during Acute Inflammation Induced by Human Experimental Endotoxemia

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New observations on the trafficking and diapedesis of monocytes

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Mesenchymal Stem/Stromal Cells Induce the Generation of Novel IL-10–Dependent Regulatory Dendritic Cells by SOCS3 Activation

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Origin and Heterogeneity of Tissue Myeloid Cells: A Focus on GMP-Derived Monocytes and Neutrophils

Ng, L. G., Liu, Z., Kwok, I., & Ginhoux, F. (2023) · Annual Review of Immunology · doi:10.1146/annurev-immunol-081022-113627 · Cited by 91

Activation of Invariant NKT Cells in Early Phase of Experimental Autoimmune Encephalomyelitis Results in Differentiation of Ly6Chi Inflammatory Monocyte to M2 Macrophages and Improved Outcome

Denney, L., Kok, W. L., Cole, S., Sanderson, S., McMichael, A. J., & Ho, L. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103608 · Cited by 87

The journey from stem cell to macrophage

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CX3CR1 Reduces Kidney Fibrosis by Inhibiting Local Proliferation of Profibrotic Macrophages

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CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice

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Chemokines and NK cells: Regulators of development, trafficking and functions

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Monocytes, Macrophages, and Their Potential Niches in Synovial Joints – Therapeutic Targets in Post-Traumatic Osteoarthritis?

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Monocytes and macrophages in flow: an ESCCA initiative on advanced analyses of monocyte lineage using flow cytometry

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Migration of blood cells to β-amyloid plaques in Alzheimer's disease

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Hematopoietic CC-Chemokine Receptor 2 (CCR2) Competent Cells Are Protective for the Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer’s Disease

Naert, G., & Rivest, S. (2011) · Molecular Medicine · doi:10.2119/molmed.2011.00306 · Cited by 77

Molecular cues guiding inflammatory responses

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Energy metabolism manipulates the fate and function of tumour myeloid-derived suppressor cells

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The Interferon-Stimulated Gene Ifi27l2a Restricts West Nile Virus Infection and Pathogenesis in a Cell-Type- and Region-Specific Manner

Lucas, T. M., Richner, J. M., & Diamond, M. S. (2015) · Journal of Virology · doi:10.1128/jvi.02463-15 · Cited by 77

Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4 + T cells

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2014 Jeffrey M. Hoeg Award Lecture

Zhu, Y. P., Thomas, G. D., & Hedrick, C. C. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.304054 · Cited by 77

Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice

Kostadinova, F. I., Baba, T., Ishida, Y., Kondo, T., Popivanova, B. K., & Mukaida, N. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.1109768 · Cited by 72

Phenotypic and functional analysis of monocyte populations in cattle peripheral blood identifies a subset with high endocytic and allogeneic T-cell stimulatory capacity

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Transcriptional control of dendritic cell development and functions

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Altered compensatory cytokine signaling underlies the discrepancy between Flt3–/– and Flt3l–/– mice

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Monocyte-mediated defense against bacteria, fungi, and parasites

Lauvau, G. S., Loke, P., & Hohl, T. M. (2015) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.014 · Cited by 71

The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO

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Molecular control of monocyte development

Terry, R. L., & Miller, S. D. (2014) · Cellular Immunology · doi:10.1016/j.cellimm.2014.02.008 · Cited by 75

Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

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Macrophages in Transplantation: A Matter of Plasticity, Polarization, and Diversity

Panzer, S. E. (2021) · Transplantation · doi:10.1097/tp.0000000000003804 · Cited by 70

Myeloid cells in atherosclerosis

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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

Trzebanski, S., Kim, J., Larossi, N., Raanan, A., Kancheva, D., Bastos, J., Haddad, M., Solomon, A., Sivan, E., Aizik, D., et al. (2024) · Immunity · doi:10.1016/j.immuni.2024.04.019 · Cited by 71

Inflammatory monocyte effector mechanisms

Lauvau, G. S., Chorro, L., Spaulding, E., & Soudja, S. M. (2014) · Cellular Immunology · doi:10.1016/j.cellimm.2014.07.007 · Cited by 69

Regulation and consequences of monocytosis

Dutta, P., & Nahrendorf, M. (2014) · Immunological Reviews · doi:10.1111/imr.12219 · Cited by 66

The intimate relationship between human cytomegalovirus and the dendritic cell lineage

Sinclair, J. H., & Reeves, M. B. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00389 · Cited by 64

Innate and Adaptive Immune Responses duringListeria monocytogenesInfection

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Redefining Myeloid Cell Subsets in Murine Spleen

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PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function

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Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus

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CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia

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Selective recruitment of non-classical monocytes promotes skeletal muscle repair

Emeterio, C. L. S., Olingy, C. E., Chu, Y., & Botchwey, E. A. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.11.021 · Cited by 59

STING/MPYS Mediates Host Defense against Listeria monocytogenes Infection by Regulating Ly6Chi Monocyte Migration

Jin, L., Getahun, A., Knowles, H. M., Mogan, J., Akerlund, L. J., Packard, T. A., Perraud, A., & Cambier, J. C. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1201788 · Cited by 56

The Innate Immune Response in Myocardial Infarction, Repair, and Regeneration

Gentek, R., & Hoeffel, G. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-57613-8_12 · Cited by 58

Macrophages as key regulators of liver health and disease

Papachristoforou, E., & Ramachandran, P. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.04.006 · Cited by 56

Chemokines and Skin Diseases

Sugaya, M. (2014) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-014-0313-y · Cited by 55

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1

Xi, H., Katschke, K. J., Helmy, K. Y., Wark, P. A., Kljavin, N. M., Clark, H. F., Eastham‐Anderson, J., Shek, T., Roose‐Girma, M., Ghilardi, N., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20091508 · Cited by 54

TGF-β1 Accelerates Dendritic Cell Differentiation from Common Dendritic Cell Progenitors and Directs Subset Specification toward Conventional Dendritic Cells

Felker, P., Seré, K. M., Lin, Q., Becker, C., Hristov, M., Hieronymus, T., & Zenke, M. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903950 · Cited by 54

Fate Mapping of Dendritic Cells

Poltorak, M. P., & Schraml, B. U. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00199 · Cited by 53

The Ontogeny and Microenvironmental Regulation of Tumor-Associated Macrophages

Movahedi, K., & Ginderachter, J. A. V. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6704 · Cited by 53

Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke

Chen, C., Jiang, W., Liu, Z., Li, F., Yang, J., Zhao, Y., Ran, Y., Meng, Y., Ji, X., Geng, X., et al. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1190-9 · Cited by 53

Monocyte progenitors give rise to multinucleated giant cells

Lößlein, A. K., Lohrmann, F., Scheuermann, L., Gharun, K., Neuber, J., Kolter, J., Forde, A. J., Kleimeyer, C., Poh, Y. Y., Mack, M., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22103-5 · Cited by 52

Dissecting the Autocrine and Paracrine Roles of the CCR2-CCL2 Axis in Tumor Survival and Angiogenesis

Izhak, L., Wildbaum, G., Jung, S., Stein, A., Shaked, Y., & Karin, N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0028305 · Cited by 52

Monocytes from Irf5−/− Mice Have an Intrinsic Defect in Their Response to Pristane-Induced Lupus

Yang, L., Feng, D., Bi, X., Stone, R. C., & Barnes, B. J. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201162 · Cited by 52

Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor

Xiao, Y., Palomero, J., Grabowska, J. A., Wang, L., de Rink, I., van Helvert, L., & Borst, J. G. (2017) · Blood Advances · doi:10.1182/bloodadvances.2017008540 · Cited by 52

Alginate-based biomaterial-mediated regulation of macrophages in bone tissue engineering

Li, Y., Xu, Z., Wang, J., Pei, X., Chen, J., & Wan, Q. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123246 · Cited by 52

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder

Satpathy, A. T., Briseño, C. G., Cai, X., Michael, D. G., Chou, C., Hsiung, S., Bhattacharya, D., Speck, N. A., & Egawa, T. (2014) · Blood · doi:10.1182/blood-2013-11-539643 · Cited by 54

mTOR masters monocyte development in bone marrow by decreasing the inhibition of STAT5 on IRF8

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Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules

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Monocytic cells derived from human embryonic stem cells and fetal liver share common differentiation pathways and homeostatic functions

Klimchenko, O., Stefano, A. D., Geoerger, B., Hamidi, S., Opolon, P., Robert, T., Routhier, M., Benna, J. E., Delezoide, A., Boukour, S., et al. (2010) · Blood · doi:10.1182/blood-2010-07-295246 · Cited by 50

Cloning and expression of porcine Colony Stimulating Factor-1 (CSF-1) and Colony Stimulating Factor-1 Receptor (CSF-1R) and analysis of the species specificity of stimulation by CSF-1 and Interleukin 34

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Insights into CSF-1R Expression in the Tumor Microenvironment

Tomassetti, C., Insinga, G., Gimigliano, F., Morrione, A., Giordano, A., & Giurisato, E. (2024) · Biomedicines · doi:10.3390/biomedicines12102381 · Cited by 51

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In Brief

(2006) · Nature reviews. Immunology · doi:10.1038/nri1767

PS1: Dendritic cell and macrophage ontogeny

Ginhoux, F. (2014)