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Cited by 3,824

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

Open access
Dulbecco, R., Vogt, Marguerite·1954·Journal of Experimental Medicine
DOI 10.1084/jem.99.2.167
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Abstract

Plaques have been produced with the three types of poliomyelitis viruses on monolayer tissue cultures of monkey kidney and monkey testis. The number of plaques was proportional to the concentration of the virus. Each plaque originates, therefore, from a single virus particle, defined as the virus unit that is unseparable by dilution. The plaques are due to the specific action of the virus since they are suppressed by type-specific antiserum. Pure virus lines were established by isolating the virus population produced in single plaques. These derived virus lines had the same morphological, serological, and pathogenic properties as the parent strain. High titer virus stocks, with titers up to 7 x 108 plaque-forming particles per ml., were obtained.

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Crossref · 10.1084/jem.99.2.167

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Metadata

Authors
Dulbecco, R., & Vogt, M.
Venue
Journal of Experimental Medicine
Publisher
Rockefeller University Press
Published
1954-02-01
Volume
99
Issue
2
Pages
167-182
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
DOI
10.1084/jem.99.2.167
OpenAlex
W2046171723
Cited by
3,824
References
1
FWCI
83.28
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.