Three-Dimensional Cell Culture Matrices: State of the Art

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915

Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites

Decher, G. (1997) · Science · doi:10.1126/science.277.5330.1232 · Cited by 10,036

Tissue engineering

Langer, R., & Vacanti, J. P. (1993) · Science · doi:10.1126/science.8493529 · Cited by 9,893

Porosity of 3D biomaterial scaffolds and osteogenesis

Karageorgiou, V., & Kaplan, D. L. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.02.002 · Cited by 6,639

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382

Molecular Cell Biology

Lodish, H. F. (1986) · Cited by 5,650

Hydrogels for Tissue Engineering

Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,295

Hydrogels for tissue engineering: scaffold design variables and applications

Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136

Biomaterials Science: An Introduction to Materials in Medicine

Ratner, B. D., Hoffman, A. S., Schöen, F. J., & Lemons, J. E. (1996) · doi:10.1016/c2009-0-02433-7 · Cited by 5,125

Porous scaffold design for tissue engineering

Hollister, S. J. (2005) · Nature Materials · doi:10.1038/nmat1421 · Cited by 3,979

Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers

Hartgerink, J. D., Beniash, E., & Stupp, S. I. (2001) · Science · doi:10.1126/science.1063187 · Cited by 3,607

Fabrication of novel biomaterials through molecular self-assembly

Zhang, S. (2003) · Nature Biotechnology · doi:10.1038/nbt874 · Cited by 3,375

Designing materials for biology and medicine

Langer, R., & Tirrell, D. A. (2004) · Nature · doi:10.1038/nature02388 · Cited by 3,198

Taking Cell-Matrix Adhesions to the Third Dimension

Cukierman, E., Pankov, R., Stevens, D. R., & Yamada, K. M. (2001) · Science · doi:10.1126/science.1064829 · Cited by 3,027

Third-Generation Biomedical Materials

Hench, L. L., & Polak, J. M. (2002) · Science · doi:10.1126/science.1067404 · Cited by 2,794

Exploring and Engineering the Cell Surface Interface

Stevens, M. M., & George, J. H. (2005) · Science · doi:10.1126/science.1106587 · Cited by 2,607

Tissue Engineering--Current Challenges and Expanding Opportunities

Griffith, L. G., & Naughton, G. K. (2002) · Science · doi:10.1126/science.1069210 · Cited by 2,348

Capturing complex 3D tissue physiology in vitro

Griffith, L. G., & Swartz, M. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1858 · Cited by 2,347

Electrospinning of Polymeric Nanofibers for Tissue Engineering Applications: A Review

Pham, Q. P., Sharma, U., & Mikos, A. G. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1197 · Cited by 2,303

Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers

Silva, G. A., Czeisler, C. M., Niece, K. L., Beniash, E., Harrington, D. A., Kessler, J. A., & Stupp, S. I. (2004) · Science · doi:10.1126/science.1093783 · Cited by 2,179

Principles of Tissue Engineering

(2014) · Elsevier eBooks · doi:10.1016/c2011-0-07193-4 · Cited by 1,912

Alginate Hydrogels as Biomaterials

Augst, A., Kong, H. J., & Mooney, D. J. (2006) · Macromolecular Bioscience · doi:10.1002/mabi.200600069 · Cited by 1,905

Tissue-engineered autologous bladders for patients needing cystoplasty

Atala, A., Bauer, S. B., Söker, S., Yoo, J. J., & Retik, A. B. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68438-9 · Cited by 1,857

Functional Arteries Grown in Vitro

Niklason, L. E., Gao, J., Abbott, W. M., Hirschi, K. K., Houser, S. L., Marini, R. P., & Langer, R. (1999) · Science · doi:10.1126/science.284.5413.489 · Cited by 1,767

Polymeric system for dual growth factor delivery

Richardson, T. P., Peters, M. C., Ennett, A. B., & Mooney, D. J. (2001) · Nature Biotechnology · doi:10.1038/nbt1101-1029 · Cited by 1,753

Socializing with the Neighbors

Fuchs, E. V., Tumbar, T., & Guasch, G. (2004) · Cell · doi:10.1016/s0092-8674(04)00255-7 · Cited by 1,737

Mediation of biomaterial-cell interactions by adsorbed proteins: a review

Wilson, C. J., Clegg, R. E., Leavesley, D. I., & Pearcy, M. J. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.1 · Cited by 1,696

Matrigel: Basement membrane matrix with biological activity

Kleinman, H. K., & Martin, G. R. (2005) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2005.05.004 · Cited by 1,673

Biomimetic materials for tissue engineering

Shin, H., Jo, S., & Mikos, A. G. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00339-9 · Cited by 1,616

Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering

Williams, J. M., Adewunmi, A., Schek, R. M., Flanagan, C. L., Krebsbach, P. H., Feinberg, S. E., Hollister, S. J., & Das, S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.11.057 · Cited by 1,566

Synthetic Matrix Metalloproteinase-Sensitive Hydrogels for the Conduction of Tissue Regeneration: Engineering Cell-Invasion Characteristics

Lutolf, M. P., Lauer-Fields, J. L., Schmoekel, H. G., Metters, A. T., Weber, F. E., Fields, G. B., & Hubbell, J. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0737381100 · Cited by 1,508

Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: Part 1. Structure, gelation rate and mechanical properties

Kuo, C. K., & Ma, P. X. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00201-5 · Cited by 1,497

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

Weaver, V. M., Petersen, O. W., Wang, F., Larabell, C. A., Briand, P., Damsky, C., & Bissell, M. J. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.1.231 · Cited by 1,483

Bone-marrow haematopoietic-stem-cell niches

Wilson, A., & Trumpp, A. (2006) · Nature reviews. Immunology · doi:10.1038/nri1779 · Cited by 1,420

Gold nanoparticles: a new X-ray contrast agent

Hainfeld, J. F., Slatkin, D. N., Focella, T. M., & Smilowitz, H. M. (2006) · British Journal of Radiology · doi:10.1259/bjr/13169882 · Cited by 1,351

Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation

Vacanti, J. P., & Langer, R. (1999) · The Lancet · doi:10.1016/s0140-6736(99)90247-7 · Cited by 1,335

Biomedical Applications of Layer‐by‐Layer Assembly: From Biomimetics to Tissue Engineering

Tang, Z., Wang, Y., Podsiadlo, P., & Kotov, N. A. (2006) · Advanced Materials · doi:10.1002/adma.200600113 · Cited by 1,305

Engineering vascularized skeletal muscle tissue

Levenberg, S., Rouwkema, J., Macdonald, M. L., Garfein, E. S., Kohane, D. S., Darland, D. C., Marini, R. P., van Blitterswijk, C., Mulligan, R. C., D'Amore, P. A., et al. (2005) · Nature Biotechnology · doi:10.1038/nbt1109 · Cited by 1,293

Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering

Wei, G., & Ma, P. X. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.12.005 · Cited by 1,271

Biology's new dimension

Abbott, A. (2003) · Nature · doi:10.1038/424870a · Cited by 1,228

Preparation and characterization of poly(l-lactic acid) foams

Mikos, A. G., Thorsen, A. J., Czerwonka, L. A., Bao, Y., Langer, R., Winslow, D. N., & Vacanti, J. P. (1994) · Polymer · doi:10.1016/0032-3861(94)90953-9 · Cited by 1,196

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

Zaman, M. H., Trapani, L. M., Sieminski, A. L., MacKellar, D. C., Gong, H., Kamm, R. D., Wells, A. H., Lauffenburger, D. A., & Matsudaira, P. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604460103 · Cited by 1,159

Progress and opportunities for tissue-engineered skin

MacNeil, S. (2007) · Nature · doi:10.1038/nature05664 · Cited by 1,147

Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems

Hutmacher, D. W., Sittinger, M., & Risbud, M. V. (2004) · Trends in biotechnology · doi:10.1016/j.tibtech.2004.05.005 · Cited by 1,133

Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds

Holmes, T. C., Lacalle, S. D., Su, X., Liu, G., Rich, A., & Zhang, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.12.6728 · Cited by 1,124

Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs

Leong, K. F., Cheah, C. M., & Chua, C. K. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00030-9 · Cited by 1,090

Novel approach to fabricate porous sponges of poly(d,l-lactic-co-glycolic acid) without the use of organic solvents

Mooney, D. J., Baldwin, D. F., Suh, N. P., Vacanti, J. P., & Langer, R. (1996) · Biomaterials · doi:10.1016/0142-9612(96)87284-x · Cited by 1,085

Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds

Zhang, Y., Ouyang, H., Lim, C. T., Ramakrishna, S., & Huang, Z. (2004) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.30128 · Cited by 1,074

Synthetic nano-scale fibrous extracellular matrix

Ma, P. X., & Zhang, R. (1999) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199907)46:1 · Cited by 1,065

Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair

Kisiday, J. D., Jin, M. M., Kurz, B., Hung, H.-H. K., Semino, C. E., Zhang, S., & Grodzinsky, A. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.142309999 · Cited by 1,045

Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers

Singh, R. N., Pantarotto, D., Lacerda, L., Pastorin, G., Klumpp, C., Prato, M., Bianco, A., & Kostarelos, K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509009103 · Cited by 1,042

Inkjet printing of viable mammalian cells

Xu, T., Jin, J., Gregory, C., Hickman, J. J., & Boland, T. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.04.011 · Cited by 1,036

Modelling glandular epithelial cancers in three-dimensional cultures

Debnath, J., & Brugge, J. S. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1695 · Cited by 1,036

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

Teng, Y. D., Lavik, E., Qu, X., Park, K. I., Ourednik, J., Zurakowski, D., Langer, R., & Snyder, E. Y. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052678899 · Cited by 967

Electrospun Poly(ε-caprolactone) Microfiber and Multilayer Nanofiber/Microfiber Scaffolds: Characterization of Scaffolds and Measurement of Cellular Infiltration

Pham, Q. P., Sharma, U., & Mikos, A. G. (2006) · Biomacromolecules · doi:10.1021/bm060680j · Cited by 951

An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles

Rabin, O., Perez, J. M., Grimm, J., Wojtkiewicz, G. R., & Weissleder, R. (2006) · Nature Materials · doi:10.1038/nmat1571 · Cited by 941

Antibiofouling Polymer-Coated Gold Nanoparticles as a Contrast Agent for in Vivo X-ray Computed Tomography Imaging

Kim, D., Park, S.-J., Lee, J. H., Jeong, Y. Y., & Jon, S. (2007) · Journal of the American Chemical Society · doi:10.1021/ja071471p · Cited by 891

ENGINEERING PRINCIPLES OF CLINICAL CELL-BASED TISSUE ENGINEERING

Muschler, G. F., Nakamoto, C., & Griffith, L. G. (2004) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-200407000-00029 · Cited by 881

Enzyme-catalysed assembly of DNA hydrogel

Um, S. H., Lee, J. B., Park, N., Kwon, S. Y., Umbach, C. C., & Luo, D. (2006) · Nature Materials · doi:10.1038/nmat1741 · Cited by 876

Repair of bone defects using synthetic mimetics of collagenous extracellular matrices

Lutolf, M. P., Weber, F. E., Schmoekel, H. G., Schense, J. C., Kohler, T., Müller, R., & Hubbell, J. A. (2003) · Nature Biotechnology · doi:10.1038/nbt818 · Cited by 850

Molecular self-assembly of surfactant-like peptides to form nanotubes and nanovesicles

Vauthey, S., Santoso, S., Gong, H., Watson, N., & Zhang, S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072089599 · Cited by 835

Engineering tumors with 3D scaffolds

Fischbach, C., Chen, R., Matsumoto, T., Schmelzle, T., Brugge, J. S., Polverini, P. J., & Mooney, D. J. (2007) · Nature Methods · doi:10.1038/nmeth1085 · Cited by 834

Rapid prototyping in tissue engineering: challenges and potential

Yeong, W. Y., Chua, C. K., Leong, K. F., & Chandrasekaran, M. (2004) · Trends in biotechnology · doi:10.1016/j.tibtech.2004.10.004 · Cited by 805

Nano neuro knitting: Peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision

Ellis-Behnke, R. G., Liang, Y., You, S., Tay, D., Zhang, S., So, K., & Schneider, G. E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600559103 · Cited by 803

Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA–PEG block copolymers

Luu, Y. K., Kim, K., Hsiao, B. S., Chu, B., & Hadjiargyrou, M. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00097-x · Cited by 797

β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

Weaver, V. M., Lelièvre, S. A., Lakins, J. N., Chrenek, M. A., Jones, J., Giancotti, F. G., Werb, Z., & Bissell, M. J. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00125-3 · Cited by 794

Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering

Kim, S. S., Park, M. S., Jeon, O., Choi, C. Y., & Kim, B. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.08.016 · Cited by 766

A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage

Moutos, F. T., Freed, L. E., & Guilak, F. (2007) · Nature Materials · doi:10.1038/nmat1822 · Cited by 741

Nano‐fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment

Woo, K. M., Chen, V. J., & Ma, P. X. (2003) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.10098 · Cited by 718

Growth and transplantation of a custom vascularised bone graft in a man

Warnke, P. H., Springer, I. N. G., Wiltfang, J., Açil, Y., Eufinger, H., Wehmöller, M., Russo, P., Bolte, H., Sherry, E., Behrens, E., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16935-3 · Cited by 713

Indirect solid free form fabrication of local and global porous, biomimetic and composite 3D polymer-ceramic scaffolds

Taboas, J. M., Maddox, R., Krebsbach, P. H., & Hollister, S. J. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00276-4 · Cited by 691

Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation

Keselowsky, B. G., Collard, D. M., & García, A. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407356102 · Cited by 687

Membrane Type I Matrix Metalloproteinase Usurps Tumor Growth Control Imposed by the Three-Dimensional Extracellular Matrix

Hotary, K. B., Allen, E. D., Brooks, P. C., Datta, N. S., Long, M. W., & Weiss, S. J. (2003) · Cell · doi:10.1016/s0092-8674(03)00513-0 · Cited by 674

Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids

Li, S. (1999) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(1999)48:3 · Cited by 671

DNA delivery from polymer matrices for tissue engineering

Shea, L. D., Smiley, E. C., Bonadio, J. F., & Mooney, D. J. (1999) · Nature Biotechnology · doi:10.1038/9853 · Cited by 668

Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

Wang, F., Weaver, V. M., Petersen, O. W., Larabell, C. A., Dedhar, S., Briand, P., Lupu, R., & Bissell, M. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14821 · Cited by 653

Carbon Nanotube Substrates Boost Neuronal Electrical Signaling

Lovat, V., Pantarotto, D., Lagostena, L., Cacciari, B., Grandolfo, M., Righi, M., Spalluto, G., Prato, M., & Ballerini, L. (2005) · Nano Letters · doi:10.1021/nl050637m · Cited by 648

A novel method to fabricate bioabsorbable scaffolds

Whang, K., Thomas, C. H., Healy, K. E., & Nuber, G. (1995) · Polymer · doi:10.1016/0032-3861(95)93115-3 · Cited by 639

Biodegradable Polymer Scaffolds with Well-Defined Interconnected Spherical Pore Network

Ma, P. X., & Choi, J. (2001) · Tissue Engineering · doi:10.1089/107632701300003269 · Cited by 621

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

Ml, L., Aggeler, J., Farson, D. A., Hatier, C., Hassell, J. R., & Bissell, M. J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.1.136 · Cited by 620

Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures

Nelson, C. M., VanDuijn, M. M., Inman, J. L., Fletcher, D. A., & Bissell, M. J. (2006) · Science · doi:10.1126/science.1131000 · Cited by 616

Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold

Li, W., Tuli, R., Huang, X., Laquerrière, P., & Tuan, R. S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.01.002 · Cited by 615

A three-dimensional osteochondral composite scaffold for articular cartilage repair

Sherwood, J. K., Riley, S. L., Palazzolo, R. D., Brown, S. C., Monkhouse, D. C., Coates, M., Griffith, L. G., Landeen, L. K., & Ratcliffe, A. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00223-5 · Cited by 611

Technology of mammalian cell encapsulation

Uludağ, H., de Vos, P., & Tresco, P. A. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00053-3 · Cited by 602

Cell encapsulation: Promise and progress

Orive, G., Hernández, R. M., Rodríguez‐Gascón, A., Calafiore, R., Chang, T. M. S., de Vos, P., Hortelano, G., Hunkeler, D. J., Lacı́k, I., Shapiro, A. M. J., et al. (2003) · Nature Medicine · doi:10.1038/nm0103-104 · Cited by 593

Sustained Release of Proteins from Electrospun Biodegradable Fibers

Chew, S. Y., Wen, J., Yim, E. K. F., & Leong, K. W. (2005) · Biomacromolecules · doi:10.1021/bm0501149 · Cited by 584

Transdermal photopolymerization for minimally invasive implantation

Elisseeff, J. H., Anseth, K. S., Sims, D. C., McIntosh, W., Randolph, M. A., & Langer, R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3104 · Cited by 576

Use of stereolithography to manufacture critical‐sized 3D biodegradable scaffolds for bone ingrowth

Cooke, M. N., Fisher, J. P., Dean, D., Rimnac, C. M., & Mikos, A. G. (2002) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.10485 · Cited by 571

Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures

Almany, L., & Seliktar, D. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.047 · Cited by 559

Probing the role of multicellular organization in three-dimensional microenvironments

Albrecht, D. R., Underhill, G. H., Wassermann, T., Sah, R. L., & Bhatia, S. N. (2006) · Nature Methods · doi:10.1038/nmeth873 · Cited by 553

ECM signalling: orchestrating cell behaviour and misbehaviour

Lukashev, M. (1998) · Trends in Cell Biology · doi:10.1016/s0962-8924(98)01362-2 · Cited by 551

3D fiber-deposited scaffolds for tissue engineering: Influence of pores geometry and architecture on dynamic mechanical properties

Moroni, L., de Wijn, J. R., & van Blitterswijk, C. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.07.023 · Cited by 545

Cell‐Responsive Synthetic Hydrogels

Lütolf, M. P., Raeber, G. P., Zisch, A. H., Tirelli, N., & Hubbell, J. A. (2003) · Advanced Materials · doi:10.1002/adma.200304621 · Cited by 526

Controlled assembly of dendrimer-like DNA

Li, Y., Tseng, Y. D., Kwon, S. Y., d'Espaux, L., Bunch, J. S., McEuen, P. L., & Luo, D. (2003) · Nature Materials · doi:10.1038/nmat1045 · Cited by 483

Cell migration in 3D matrix

Even‐Ram, S., & Yamada, K. M. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.08.015 · Cited by 479

Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

Hyafil, F., Cornily, J.-C., Feig, J. E., Gordon, R., Vucic, E., Amirbekian, V., Fisher, E. A., Fuster, V., Feldman, L. J., & Fayad, Z. A. (2007) · Nature Medicine · doi:10.1038/nm1571 · Cited by 467

Tissue architecture: the ultimate regulator of breast epithelial function

Bissell, M. J., Rizki, A., & Mian, S. I. (2003) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2003.10.016 · Cited by 465

Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels

Tsang, V. L., Chen, A. A., Cho, L. M., Jadin, K. D., Sah, R. L., DeLong, S., West, J. L., & Bhatia, S. N. (2007) · The FASEB Journal · doi:10.1096/fj.06-7117com · Cited by 462

Biodegradable polymers applied in tissue engineering research: a review

Martina, M., & Hutmacher, D. W. (2006) · Polymer International · doi:10.1002/pi.2108 · Cited by 458

Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives

Prestwich, G. D., Marecak, D. M., Marecek, J. F., Vercruysse, K. P., & Ziebell, M. R. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(97)00242-3 · Cited by 423

Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells

Simmons, C. A., Alsberg, E., Hsiong, S. X., Kim, W. J., & Mooney, D. J. (2004) · Bone · doi:10.1016/j.bone.2004.02.027 · Cited by 413

In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation

Datta, N., Pham, Q. P., Sharma, U., Sikavitsas, V. I., Jansen, J. A., & Mikos, A. G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505661103 · Cited by 411

Three‐Dimensional Biochemical and Biomechanical Patterning of Hydrogels for Guiding Cell Behavior

Hahn, M. S., Miller, J. S., & West, J. L. (2006) · Advanced Materials · doi:10.1002/adma.200600647 · Cited by 407

Scaffolding In Tissue Engineering

Ma, P. X., & Elisseeff, J. H. (2005) · CRC Press eBooks · doi:10.1201/9781420027563 · Cited by 406

Collecting Electrospun Nanofibers with Patterned Electrodes

Li, D., Ouyang, G., McCann, J. T., & Younan Xia, A. (2005) · Nano Letters · doi:10.1021/nl0504235 · Cited by 405

Salt Fusion: An Approach to Improve Pore Interconnectivity within Tissue Engineering Scaffolds

Murphy, W. L., Dennis, R. G., Kileny, J., & Mooney, D. J. (2002) · Tissue Engineering · doi:10.1089/107632702753503045 · Cited by 392

Tissue-Engineered Follicles Produce Live, Fertile Offspring

Xu, M., Kreeger, P. K., Shea, L. D., & Woodruff, T. K. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.2739 · Cited by 387

A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity

Lin, C. Y., Kikuchi, N., & Hollister, S. J. (2003) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2003.09.029 · Cited by 387

Physical properties of alginate hydrogels and their effects on in vitro follicle development

West, E. R., Xu, M., Woodruff, T. K., & Shea, L. D. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.001 · Cited by 380

Direct Freeform Fabrication of Seeded Hydrogels in Arbitrary Geometries

Cohen, D. L., Malone, E., Lipson, H., & Bonassar, L. J. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1325 · Cited by 360

Co‐electrospun poly(lactide‐co‐glycolide), gelatin, and elastin blends for tissue engineering scaffolds

Li, M., Mondrinos, M. J., Chen, X., Gandhi, M., Ko, F., & Lelkes, P. I. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30833 · Cited by 359

Generation of Three-Dimensional Hepatocyte/Gelatin Structures with Rapid Prototyping System

Wang, X., Yan, Y., Pan, Y., Xiong, Z., Liu, H., Cheng, J., Liu, F., Lin, F., Wu, R., Zhang, R., et al. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.83 · Cited by 353

Color Textbook of Histology

P.Gartner, L., & Hiatt, J. L. (1997) · Cited by 346

Nano-fibrous poly(l-lactic acid) scaffolds with interconnected spherical macropores

Chen, V. J., & Ma, P. X. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.08.058 · Cited by 345

An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture

Zhong, S., Teo, W. E., Zhu, X., Beuerman, R. W., Ramakrishna, S., & Yung, L. Y. L. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30870 · Cited by 341

Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension

Schense, J. C., Bloch, J., Aebischer, P., & Hubbell, J. A. (2000) · Nature Biotechnology · doi:10.1038/74473 · Cited by 339

Computer‐aided tissue engineering: overview, scope and challenges

Sun, W., Darling, A., Starly, B., & Nam, J. (2004) · Biotechnology and Applied Biochemistry · doi:10.1042/ba20030108 · Cited by 338

Successful Differentiation of Mouse Neural Stem Cells on Layer-by-Layer Assembled Single-Walled Carbon Nanotube Composite

Jan, E., & Kotov, N. A. (2007) · Nano Letters · doi:10.1021/nl0620132 · Cited by 334

Alginate‐Based Nanofibrous Scaffolds: Structural, Mechanical, and Biological Properties

Bhattarai, N., Li, Z., Edmondson, D., & Zhang, M. (2006) · Advanced Materials · doi:10.1002/adma.200502537 · Cited by 328

Building drug delivery into tissue engineering design

Saltzman, W. M., & Olbricht, W. L. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd744 · Cited by 319

Framework for optimal design of porous scaffold microstructure by computational simulation of bone regeneration

ADACHI, T., OSAKO, Y., TANAKA, M., Hojo, M., & Hollister, S. J. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.02.039 · Cited by 317

The effect of hydrogel charge density on cell attachment

Schneider, G. B., English, A. E., Abraham, M. S., Zaharias, R. S., Stanford, C. M., & Keller, J. C. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.084 · Cited by 314

Tissue Engineering of Articular Cartilage with Biomimetic Zones

Klein, T. J., Malda, J., Sah, R. L., & Hutmacher, D. W. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0563 · Cited by 314

Pure and doped boron nitride nanotubes

Terrones, M., Romo-Herrera, J. M., Cruz‐Silva, E., Lopéz‐Urías, F., Muñoz‐Sandoval, E., Velázquez‐Salazar, J. J., Terrones, H., Bando, Y., & Golberg, D. V. (2007) · Materials Today · doi:10.1016/s1369-7021(07)70077-9 · Cited by 313

FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness

Kong, H. J., Polte, T. R., Alsberg, E., & Mooney, D. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405873102 · Cited by 308

Fabrication of porous ultra-short single-walled carbon nanotube nanocomposite scaffolds for bone tissue engineering

Shi, X. C., Sitharaman, B., Pham, Q. P., Liang, F., Wu, K., Billups, W. E., Wilson, L. J., & Mikos, A. G. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.05.033 · Cited by 307

Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films

Wood, K. C., Chuang, H. F., Batten, R. D., Lynn, D. M., & Hammond, P. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602884103 · Cited by 270

The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels

Kreeger, P. K., Deck, J. W., Woodruff, T. K., & Shea, L. D. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.06.016 · Cited by 264

The effect of structural alterations of PEG-fibrinogen hydrogel scaffolds on 3-D cellular morphology and cellular migration

Dikovsky, D., Bianco‐Peled, H., & Seliktar, D. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.09.038 · Cited by 256

Nanostructured Polymer/Nanophase Ceramic Composites Enhance Osteoblast and Chondrocyte Adhesion

Kay, S., Thapa, A., Haberstroh, K. M., & Webster, T. J. (2002) · Tissue Engineering · doi:10.1089/10763270260424114 · Cited by 253

Macroporous and nanofibrous polymer scaffolds and polymer/bone‐like apatite composite scaffolds generated by sugar spheres

Wei, G., & Ma, P. X. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30704 · Cited by 251

Chondrocyte Phenotype in Engineered Fibrous Matrix Is Regulated by Fiber Size

Li, W., Jiang, Y. J., & Tuan, R. S. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1775 · Cited by 250

Photo-Cross-Linking of Type I Collagen Gels in the Presence of Smooth Muscle Cells: Mechanical Properties, Cell Viability, and Function

Brinkman, W. T., Nagapudi, K., Thomas, B. S., & Chaikof, E. L. (2003) · Biomacromolecules · doi:10.1021/bm0257412 · Cited by 246

Surface-induced changes in protein adsorption and implications for cellular phenotypic responses to surface interaction

Allen, L. T., Tosetto, M., Miller, I. S., O’Connor, D. P., Penney, S. C., Lynch, I., Keenan, A. K., Pennington, S. R., Dawson, K. A., & Gallagher, W. M. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.01.019 · Cited by 245

The Importance of New Processing Techniques in Tissue Engineering

Lu, L., & Mikos, A. G. (1996) · MRS Bulletin · doi:10.1557/s088376940003181x · Cited by 244

Homogenization theory and digital imaging: A basis for studying the mechanics and design principles of bone tissue

Hollister, S. J., & Kikuchi, N. (1994) · Biotechnology and Bioengineering · doi:10.1002/bit.260430708 · Cited by 242

Synthesis and characterization of a novel degradable phosphate-containing hydrogel

Wang, D. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00280-1 · Cited by 234

Study of gelatin-containing artificial skin V: fabrication of gelatin scaffolds using a salt-leaching method

Lee, S. B., Kim, Y. H., Chong, M. S., Hong, S. H., & Lee, Y. M. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.032 · Cited by 234

Accelerated chondrocyte functions on NaOH-treated PLGA scaffolds

Park, G. E., Pattison, M. A., Park, K., & Webster, T. J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.08.005 · Cited by 232

Scaffold Design and in Vitro Study of Osteochondral Coculture in a Three-Dimensional Porous Polycaprolactone Scaffold Fabricated by Fused Deposition Modeling

Cao, T., Ho, K. H., & Teoh, S. (2003) · Tissue Engineering · doi:10.1089/10763270360697012 · Cited by 231

Porogen-based solid freeform fabrication of polycaprolactone–calcium phosphate scaffolds for tissue engineering

Mondrinos, M. J., Dembzynski, R. S., Lu, L., BYRAPOGU, V., Wootton, D. M., Lelkes, P. I., & Zhou, J. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.03.049 · Cited by 225

Three-dimensional, nano-structured PLGA scaffolds for bladder tissue replacement applications

Pattison, M. A., Wurster, S., Webster, T. J., & Haberstroh, K. M. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.011 · Cited by 223

An image-based approach for designing and manufacturing craniofacial scaffolds

Hollister, S. J., Levy, R. A., Chu, T. G., Halloran, J. W., & Feinberg, S. E. (2000) · International Journal of Oral and Maxillofacial Surgery · doi:10.1034/j.1399-0020.2000.290115.x · Cited by 219

Beyond the Petri dish

Zhang, S. (2004) · Nature Biotechnology · doi:10.1038/nbt0204-151 · Cited by 217

Anatomically shaped osteochondral constructs for articular cartilage repair

Hung, C. T., Lima, E. G., Mauck, R. L., Taki, E., LeRoux, M. A., Lu, H. H., Stark, R. G., Guo, X., & Ateshian, G. A. (2003) · Journal of Biomechanics · doi:10.1016/s0021-9290(03)00213-6 · Cited by 215

Novel Approach for the Three-Dimensional Culture of Granulosa Cell–Oocyte Complexes

Pangas, S. A., Saudye, H. A., Shea, L. D., & Woodruff, T. K. (2003) · Tissue Engineering · doi:10.1089/107632703322495655 · Cited by 210

Bone regeneration on computer-designed nano-fibrous scaffolds

Chen, V. J., Callahan, L. A. S., & Ma, P. X. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.02.043 · Cited by 208

Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates

Khademhosseini, A., Ferreira, L., Blumling, J., Yeh, J., Karp, J. M., Fukuda, J., & Langer, R. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.06.035 · Cited by 202

Adhesion of mesenchymal stem cells to polymer scaffolds occurs via distinct ECM ligands and controls their osteogenic differentiation

Chastain, S. R., Kundu, A. K., Dhar, S., Calvert, J. W., & Putnam, A. J. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30686 · Cited by 194

Immobilized nerve growth factor and microtopography have distinct effects on polarization versus axon elongation in hippocampal cells in culture

Gomez, N. V., Lu, Y., Chen, S., & Schmidt, C. E. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.07.043 · Cited by 190

Multiphoton polymerization

Li, L., & Fourkas, J. T. (2007) · Materials Today · doi:10.1016/s1369-7021(07)70130-x · Cited by 179

Tissue engineered fetal skin constructs for paediatric burns

Hohlfeld, J., Roessingh, A. D. B., Hirt‐Burri, N., Chaubert, P., Gerber, S., Scaletta, C., Hohlfeld, P., & Applegate, L. A. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67107-3 · Cited by 174

Controlling the processing of collagen-hydroxyapatite scaffolds for bone tissue engineering

Wahl, D. A., Sachlos, E., Liu, C., & Czernuszka, J. T. (2007) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-006-0682-9 · Cited by 170

Death in the third dimension: apoptosis regulation and tissue architecture

Zahir, N., & Weaver, V. M. (2003) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2003.12.005 · Cited by 165

Efficient generation of human T cells from a tissue-engineered thymic organoid

Poznansky, M. C., Evans, R. H., Foxall, R. B., Olszak, I. T., Piascik, A. H., Hartman, K. E., Brander, C., Meyer, T. H., Pykett, M. J., Chabner, K. T., et al. (2000) · Nature Biotechnology · doi:10.1038/77288 · Cited by 155

Stimulation of Neural Cells by Lateral Currents in Conductive Layer‐by‐Layer Films of Single‐Walled Carbon Nanotubes

Gheith, M. K., Pappas, T. C., Liopo, A. V., Sinani, V. A., Shim, B. S., Motamedi, M., Wicksted, J. P., & Kotov, N. A. (2006) · Advanced Materials · doi:10.1002/adma.200600878 · Cited by 154

Collagen Scaffolds Reinforced with Biomimetic Composite Nano-Sized Carbonate-Substituted Hydroxyapatite Crystals and Shaped by Rapid Prototyping to Contain Internal Microchannels

Sachlos, E., Gotora, D., & Czernuszka, J. T. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.2479 · Cited by 152

Bioactive Hydrogels with an Ordered Cellular Structure Combine Interconnected Macroporosity and Robust Mechanical Properties

Stachowiak, A. N., Bershteyn, A., Tzatzalos, E., & Irvine, D. J. (2004) · Advanced Materials · doi:10.1002/adma.200400507 · Cited by 150

Poly(ethylene glycol) Hydrogel System Supports Preadipocyte Viability, Adhesion, and Proliferation

Patel, P. N., Gobin, A. S., West, J. L., & Patrick, C. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.1498 · Cited by 148

Inverted Colloidal Crystals as Three-Dimensional Cell Scaffolds

Kotov, N. A., Liu, Y., Wang, S., Cumming, C. J., Eghtedari, M., Vargas, G., Motamedi, M., Nichols, J. E., & Cortiella, J. (2004) · Langmuir · doi:10.1021/la049958o · Cited by 146

Expansion of engrafting human hematopoietic stem/progenitor cells in three‐dimensional scaffolds with surface‐immobilized fibronectin

Feng, Q., Chai, C., Jiang, X., Leong, K. W., & Mao, H. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30829 · Cited by 145

Phosphatases in cell–matrix adhesion and migration

Larsen, M., Tremblay, M. L., & Yamada, K. M. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1199 · Cited by 143

Effect of Scaffold Design on Bone Morphology In Vitro

Uebersax, L., Hagenmüller, H., Hofmann, S., Gruenblatt, E., Müller, R., Vunjak‐Novakovic, G., Kaplan, D. L., Merkle, H. P., & Meinel, L. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.3417 · Cited by 143

Designing Zonal Organization into Tissue-Engineered Cartilage

Sharma, B., Williams, C. G., Kim, T. K., Sun, D., Malik, A. N., KHAN, M. A., Leong, K. W., & Elisseeff, J. H. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0068 · Cited by 142

Physicochemical evaluation of bioactive polymeric composites based on hybrid amorphous calcium phosphates

Škrtić, D., Antonucci, J. M., Eanes, E. D., Eichmiller, F. C., & Schumacher, G. E. (2000) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(2000)53:4 · Cited by 137

Fabrication of reconfigurable protein matrices by cracking

Zhu, X. A., Mills, K. L., Peters, P. R., Bahng, J. H., Liu, E. H., Shim, J., Naruse, K., CSETE, M. E., Thouless, M. D., & Takayama, S. (2005) · Nature Materials · doi:10.1038/nmat1365 · Cited by 136

Preparation of interconnected highly porous polymeric structures by a replication and freeze‐drying process

Hou, Q., Grijpma, D. W., & Feijén, J. (2003) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.10066 · Cited by 133

Enhancing the Drug Metabolism Activities of C3A— A Human Hepatocyte Cell Line—By Tissue Engineering Within Alginate Scaffolds

Elkayam, T., Amitay-Shaprut, S., Dvir‐Ginzberg, M., Harel, T., & Cohen, S. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1357 · Cited by 130

Surface Modification of Confined Microgeometries via Vapor-Deposited Polymer Coatings

Chen, H.-Y., Elkasabi, Y. M., & Lahann, J. (2005) · Journal of the American Chemical Society · doi:10.1021/ja057082h · Cited by 129

Enhanced liver functions of hepatocytes cocultured with NIH 3T3 in the alginate/galactosylated chitosan scaffold

Seo, S.-J., Kim, I.-Y., Choi, Y., Akaike, T., & Cho, C. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.09.018 · Cited by 126

Presentation and Recognition of Biotin on Nanofibers Formed by Branched Peptide Amphiphiles

Guler, M. O., Soukasene, S., Hulvat, J. F., & Stupp, S. I. (2004) · Nano Letters · doi:10.1021/nl048238z · Cited by 125

Tissue-Engineered Cartilage Constructs Using Composite Hyaluronic Acid/Collagen I Hydrogels and Designed Poly(Propylene Fumarate) Scaffolds

Liao, E. E., Yaszemski, M. J., Krebsbach, P. H., & Hollister, S. J. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0117 · Cited by 121

Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance

Lu, H., Chua, K. N., Zhang, P., Lim, W. S., Ramakrishna, S., Leong, K. W., & Mao, H. (2005) · Acta Biomaterialia · doi:10.1016/j.actbio.2005.04.003 · Cited by 118

Sonic hedgehog gene-enhanced tissue engineering for bone regeneration

Edwards, P. C., Ruggiero, S., Fantasia, J. E., Burakoff, R. P., Moorji, S. M., Paric, E., Razzano, P., Grande, D. A., & Mason, J. M. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302386 · Cited by 108

Biomaterials for Regenerative Medicine

Stupp, S. I. (2005) · MRS Bulletin · doi:10.1557/mrs2005.148 · Cited by 102

Robotic deposition of model hydroxyapatite scaffolds with multiple architectures and multiscale porosity for bone tissue engineering

Dellinger, J. G., Cesarano, J., & Jamison, R. D. (2007) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31072 · Cited by 101

Using a Core–Sheath Distribution of Surface Chemistry through 3D Tissue Engineering Scaffolds to Control Cell Ingress

Barry, J. J. A., Howard, D., Shakesheff, K. M., Howdle, S. M., & Alexander, M. R. (2006) · Advanced Materials · doi:10.1002/adma.200502719 · Cited by 99

Bone Formation Mediated by Synergy‐Acting Growth Factors Embedded in a Polyelectrolyte Multilayer Film

Dierich, A., Guen, E. L., Messaddeq, N., Stoltz, J. F., Netter, P., Schaaf, P., Voegel, J., & Benkirane-Jessel, N. (2007) · Advanced Materials · doi:10.1002/adma.200601271 · Cited by 95

Erratum: Porous scaffold design for tissue engineering

Hollister, S. J. (2006) · Nature Materials · doi:10.1038/nmat1683 · Cited by 93

Fibrinopeptides and fibrin gel structure

Blombäck, B., & Bark, N. (2004) · Biophysical Chemistry · doi:10.1016/j.bpc.2004.07.013 · Cited by 88

Customization of Load‐Bearing Hydroxyapatite Lattice Scaffolds

Cesarano, J., Dellinger, J. G., Saavedra, M. P., Gill, D., Jamison, R. D., Grosser, B., Sinn-Hanlon, J., & Goldwasser, M. S. (2005) · International Journal of Applied Ceramic Technology · doi:10.1111/j.1744-7402.2005.02026.x · Cited by 87

Mechanisms of cell activation by heavy metal ions

Wagner, M., Klein, C. L., van Kooten, T. G., & Kirkpatrick, C. J. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19981205)42:3 · Cited by 86

Cultivation of endothelial cells on adhesive protein-free synthetic polymer gels

Chen, Y. M., Shiraishi, N., Satokawa, H., Kakugo, A., Narita, T., Gong, J. P., Osada, Y., Yamamoto, K., & Ando, J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.11.025 · Cited by 85

Electrospinning of polycrystalline barium titanate nanofibers with controllable morphology and alignment

McCann, J. T., Chen, J. I. L., Li, D., Ye, Z., & Younan Xia, A. (2006) · Chemical Physics Letters · doi:10.1016/j.cplett.2006.04.082 · Cited by 85

Deletion of the tissue response against alginate-pll capsules by temporary release of co-encapsulated steroids

Bünger, C. M., Tiefenbach, B., Jahnke, A., Gerlach, C., Freier, T., Schmitz, K., Hopt, U. T., Schareck, W. D., Klar, E., & de Vos, P. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.017 · Cited by 83

Correlation of in vivo collagen degradation rate with in vitro measurements

Yannas, I. V., Burke, J. F., Huang, C., & Gordon, P. L. (1975) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820090608 · Cited by 82

Wet or let die

Zhang, S. (2004) · Nature Materials · doi:10.1038/nmat1047 · Cited by 82

Inverted colloidal crystals as three-dimensional microenvironments for cellular co-cultures

Lee, J., Shanbhag, S., & Kotov, N. A. (2006) · Journal of Materials Chemistry · doi:10.1039/b605797g · Cited by 82

CT-generated porous hydroxyapatite orbital floor prosthesis as a prototype bioimplant.

Levy, R. A., Chu, T. G., Halloran, J. W., Feinberg, S. E., & Hollister, S. J. (1997) · PubMed Central · Cited by 72

In vitro degradation and controlled release behavior of ,-PLGA50 and PCL-b-,-PLGA50 copolymer microspheres

Dong, C., GUO, Y., QIU, K., Gu, Z., & FENG, X. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.05.024 · Cited by 70

Inductive tissue engineering with protein and DNA-releasing scaffolds

Salvay, D. M., & Shea, L. D. (2005) · Molecular BioSystems · doi:10.1039/b514174p · Cited by 68

Three-dimensional horizontal circular spiral photonic crystals with stop gaps below 1μm

Seet, K. K., Mizeikis, V., Juodkazis, S., & Misawa, H. (2006) · Applied Physics Letters · doi:10.1063/1.2207841 · Cited by 67

Computer-Aided Tissue Engineering of a Human Vertebral Body

Wettergreen, M. A., Bucklen, B. S., Sun, W., & Liebschner, M. A. K. (2005) · Annals of Biomedical Engineering · doi:10.1007/s10439-005-6744-1 · Cited by 60

The enzymatic degradation of scaffolds and their replacement by vascularized extracellular matrix in the murine myocardium

van Amerongen, M. J., Harmsen, M. C., Petersen, A. H., Kors, G., & van Luyn, M. J. A. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.11.002 · Cited by 55

Polyelectrolyte‐Clay‐Protein Layer Films on Microfluidic PDMS Bioreactor Surfaces for Primary Murine Bone Marrow Culture

Mehta, G., Kiel, M. J., Lee, J. W., Kotov, N. A., Linderman, J. J., & Takayama, S. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200700016 · Cited by 54

Poly(lactic-co-glycolic acid) Bone Scaffolds with Inverted Colloidal Crystal Geometry

Cuddihy, M. J., & Kotov, N. A. (2008) · Tissue Engineering Part A · doi:10.1089/ten.tea.2007.0142 · Cited by 50

It takes a village to grow a tissue

Kaplan, D. L., Moon, R. T., & Vunjak‐Novakovic, G. (2005) · Nature Biotechnology · doi:10.1038/nbt1005-1237 · Cited by 45

Selective Laser Sintering of Bioceramic Materials for Implants

Barlow, J. W. (2018) · Texas ScholarWorks (Texas Digital Library) · doi:10.15781/t26q1t10x · Cited by 44

Expanding Frontiers in Biomaterials

Stupp, S. I., Donners, J. J. J. M., Li, L., & Mata, Á. (2005) · MRS Bulletin · doi:10.1557/mrs2005.276 · Cited by 43

Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker

Xu, J., Ma, M., & Purcell, W. M. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00090-5 · Cited by 34

Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors

Edmondson, R., Broglie, J. J., Adcock, A. F., & Yang, L. (2014) · ASSAY and Drug Development Technologies · doi:10.1089/adt.2014.573 · Cited by 2,515

2D and 3D Cell Cultures - a Comparison of Different Types of Cancer Cell Cultures

Kapałczyńska, M., Kolenda, T., Przybyła, W., Zajączkowska, M., Teresiak, A., Filas, V., Ibbs, M., Bliźniak, R., Łuczewski, Ł., & Lamperska, K. (2016) · Archives of Medical Science · doi:10.5114/aoms.2016.63743 · Cited by 1,499

Design properties of hydrogel tissue-engineering scaffolds

Zhu, J., & Marchant, R. E. (2011) · Expert Review of Medical Devices · doi:10.1586/erd.11.27 · Cited by 1,479

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering

Billiet, T., Vandenhaute, M., Schelfhout, J., Vlierberghe, S. V., & Dubruel, P. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.04.050 · Cited by 1,321

Additive manufacturing of tissues and organs

Melchels, F. P. W., Domingos, M. A. N., Klein, T. J., Malda, J., Bártolo, P., & Hutmacher, D. W. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.11.007 · Cited by 1,223

Micro‐Engineered 3D Scaffolds for Cell Culture Studies

Greiner, A. M., Richter, B., & Bastmeyer, M. (2012) · Macromolecular Bioscience · doi:10.1002/mabi.201200132 · Cited by 134

Biological, Natural, and Synthetic 3D Matrices

Korzhikov-Vlakh, V. A., & Pepelanova, I. (2021) · Learning materials in biosciences · doi:10.1007/978-3-030-66749-8_4 · Cited by 1

Advances in 3D cell culture technologies enabling tissue‐like structures to be created in vitro

Knight, E., & Przyborski, S. A. (2014) · Journal of Anatomy · doi:10.1111/joa.12257 · Cited by 569

3D Cell Culture Systems: Advantages and Applications

Ravi, M., Paramesh, V., Kaviya, S. R., Anuradha, E., & Solomon, F. D. P. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.24683 · Cited by 1,206

Adding depth to cell culture

Powell, K. (2017) · Science · doi:10.1126/science.356.6333.96 · Cited by 9