The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Lipid metabolism during endurance exercise
Open accessAbstract
Endogenous triacylglycerols represent an important source of fuel for endurance exercise. Triacylglycerol oxidation increases progressively during exercise; the specific rate is determined by energy requirements of working muscles, fatty acid delivery to muscle mitochondria, and the oxidation of other substrates. The catecholamine response to exercise increases lipolysis of adipose tissue triacylglycerols and, presumably, intramuscular triacylglycerols. In addition, increases in adipose tissue and muscle blood flow decrease fatty acid reesterification and facilitate the delivery of released fatty acids to skeletal muscle. Alterations in fatty acid mobilization and the relative use of adipose and intramuscular triacylglycerols during exercise depend, in large part, on degree of fitness and exercise intensity. Compared with untrained persons exercising at the same absolute intensity, persons who have undergone endurance training have greater fat oxidation during exercise without increased lipolysis. Available evidence suggests that the training-induced increase in fat oxidation is due primarily to increased oxidation of non-plasma-derived fatty acids, perhaps from intramuscular triacylglycerol stores. Fat oxidation is lower in high-intensity exercise than in moderate-intensity exercise, in part because of decreased fatty acid delivery to exercising muscles. Parenteral lipid supplementation during high-intensity exercise increases fat oxidation, but the effect of ingesting long-chain or medium-chain triacylglycerols on substrate metabolism during exercise is less clear. This review discusses the relation between fatty acid mobilization and oxidation during exercise and the effect of endurance training, exercise intensity, and lipid supplementation on these responses.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Interestingly, due to poor circulation in peripheral adipose tissue and an increased ratio of FA:albumin after exercise, the albumin binding capacity may be surpassed and high levels of unbound serum free fatty acids can create a harmful condition [15].”
From Understanding the factors that effect maximal fat oxidation. (2018) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Once FAs leave the adipocyte they first bind to albumin, which can bind as many as 12 FA molecules [15].”
From Understanding the factors that effect maximal fat oxidation. (2018) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“While FAox fluctuates continuously, the endocrine system is principally responsible for the regulation of lipid oxidation at rest and during exercise [15].”
From Understanding the factors that effect maximal fat oxidation. (2018) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“At exercise intensities <65% VO2max muscle glycogen and IMTG oxidation increase considerably to as much as 50% of energy expenditure, depending on exercise duration [15, 48].”
From Understanding the factors that effect maximal fat oxidation. (2018) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Lipolytic activity within adipose tissue and intramuscular fat is highly active during moderate-intensity endurance exercise by the action of catecholamines, leading to elevated circulating glycerol levels [134,188].”
From Regulation of Energy Substrate Metabolism in Endurance Exercise (2021) · cites this paper as [134]
Experimental — accuracy not yet measured
The cited source says what the claim attributes to it.
In the citing paper
“The exercise-induced catecholamine release stimulates lipolysis, liberating FAs from the glycerol molecule [8, 15].”
From Understanding the factors that effect maximal fat oxidation. (2018) · cites this paper as [15]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“fat is the most abundant endogenous energy depot that is >60 times the amount stored as glycogen (<3000 kcal) in humans, although this is heavily dependent on adiposity [134]”
From Regulation of Energy Substrate Metabolism in Endurance Exercise (2021) · cites this paper as [134]
The cited source says what the claim attributes to it.
In the citing paper
“sustained endurance capacity and the attenuation of glycogen depletion are largely mediated by the metabolism of fat by providing fatty acids (FA) for β-oxidation in the mitochondria [132,133,134].”
From Regulation of Energy Substrate Metabolism in Endurance Exercise (2021) · cites this paper as [134]
In the citing paper
“Exercise training increases mitochondrial content, an adaptation that supports greater ATP production but is paralleled by greater capacity for lipid oxidation (39, 40).”
In the citing paper
“During exercise, skeletal muscle also uses lipid as fuel, which originates from the triglycerides stored in muscle and free fatty acids (FFAs) released from WAT29.”
From Exerkines in health, resilience and disease (2022) · cites this paper as [29]
In the citing paper
“Exerkines are not merely cytokines, however, as hormones, neurotransmitters or metabolites associated with exercise, such as catecholamines40, lactate41 or FFAs29, can also serve as exerkines with endocrine signalling potential42.”
From Exerkines in health, resilience and disease (2022) · cites this paper as [29]
In the citing paper
“Exercise facilitates WAT lipolysis to provide FFA for utilization as fuel29.”
From Exerkines in health, resilience and disease (2022) · cites this paper as [29]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Exercise Physiology: Energy, Nutrition, and Human Performance
McArdle, W. D., Katch, F. I., & Katch, V. L. (2006) · Cited by 2,633
Romijn, J. A., Coyle, E. F., Sidossis, L. S., Gastaldelli, A., Horowitz, J. F., Endert, E., & Wolfe, R. R. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e380 · Cited by 1,747
Self-citationBiochemical Adaptations in Muscle
Holloszy, J. O. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96046-1 · Cited by 1,517
Medium-chain triglycerides: an update
Bach, A., & Babayan, V. (1982) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/36.5.950 · Cited by 1,151
Fatty acid binding to plasma albumin
Spector, A. A. (1975) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36723-7 · Cited by 970
Skeletal Muscle Adaptability: Significance for Metabolism and Performance
Saltin, B., & Gollnick, P. D. (1983) · Comprehensive physiology · doi:10.1002/cphy.cp100119 · Cited by 917
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis.
McGarry, J. D., Mannaerts, G. P., & Foster, D. W. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108764 · Cited by 736
McGarry, J. D., Mills, S. E., Long, C. S., & Foster, D. W. (1983) · Biochemical Journal · doi:10.1042/bj2140021 · Cited by 556
Muscle triglyceride utilization during exercise: effect of training
Hurley, B. F., Nemeth, P. M., Martin, W. H., Hagberg, J. M., Dalsky, G. P., & Holloszy, J. O. (1986) · Journal of Applied Physiology · doi:10.1152/jappl.1986.60.2.562 · Cited by 522
Kiens, B., Essen‐Gustavsson, B., Christensen, N. J., & Saltin, B. (1993) · The Journal of Physiology · doi:10.1113/jphysiol.1993.sp019823 · Cited by 444
Cited by
Sorted by citations
Skeletal muscle energy metabolism during exercise
Hargreaves, M., & Spriet, L. L. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0251-4 · Cited by 1,408
Exerkines in health, resilience and disease
Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., et al. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00641-2 · Cited by 927
Lipolysis and lipid mobilization in human adipose tissue
Lafontan, M., & Langin, D. (2009) · Progress in Lipid Research · doi:10.1016/j.plipres.2009.05.001 · Cited by 884
Batacan, R. B., Duncan, M. J., Dalbo, V. J., Tucker, P. S., & Fenning, A. S. (2017) · British Journal of Sports Medicine · doi:10.1136/bjsports-2015-095841 · Cited by 799
Physical Activity/Exercise and Type 2 Diabetes
Sigal, R. J., Kenny, G. P., Wasserman, D. H., & Castaneda-Sceppa, C. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2518 · Cited by 763
The Quantification of Training Load, the Training Response and the Effect on Performance
Borresen, J., & Lambert, M. (2009) · Sports Medicine · doi:10.2165/11317780-000000000-00000 · Cited by 747
Autonomic Control of Heart Rate during and after Exercise
Borresen, J., & Lambert, M. (2008) · Sports Medicine · doi:10.2165/00007256-200838080-00002 · Cited by 447
Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy
Booth, F. W., Chakravarthy, M. V., Gordon, S. E., & Spangenburg, E. E. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00073.2002 · Cited by 426
Kantartzis, K., Thamer, C., Peter, A., Machann, J., Schick, F., Schraml, C., Konigsrainer, A., Konigsrainer, I., Krober, S., Niess, A., et al. (2009) · Gut · doi:10.1136/gut.2008.151977 · Cited by 273
Virkamäki, A., Korsheninnikova, E., Seppälä‐Lindroos, A., Vehkavaara, S., Goto, T., Halavaara, J. T., Häkkinen, A., & Yki‐Järvinen, H. (2001) · Diabetes · doi:10.2337/diabetes.50.10.2337 · Cited by 261
Understanding the factors that effect maximal fat oxidation.
Purdom, T., Kravitz, L., Dokladny, K., & Mermier, C. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0207-1 · Cited by 247
“Once FAs leave the adipocyte they first bind to albumin, which can bind as many as 12 FA molecules [15].”
BackgroundInfluentialSchranner, D., Kastenmüller, G., Schönfelder, M., Römisch‐Margl, W., & Wackerhage, H. (2020) · Sports Medicine - Open · doi:10.1186/s40798-020-0238-4 · Cited by 263
The Regulation of Fat Metabolism during Aerobic Exercise
Muscella, A., Stefàno, E., Lunetti, P., Capobianco, L., & Marsigliante, S. (2020) · Biomolecules · doi:10.3390/biom10121699 · Cited by 237
Badawy, A. A. ‐. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.11.015 · Cited by 228
Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice
Murase, T., Haramizu, S., Shimotoyodome, A., Nagasawa, A., & Tokimitsu, I. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00693.2004 · Cited by 210
Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle
Zoll, J., Sanchez, H., N’guessan, B. B., Ribera, F., Lampert, E., Bigard, X. A., Serrurier, B., Fortin, D., Gény, B., Veksler, V., et al. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.019661 · Cited by 186
Eslam, M., Fan, J., Yu, M., Wong, V. W., Cua, I. H., Liu, C., Tanwandee, T., Gani, R. A., Seto, W., Alam, S., et al. (2025) · Hepatology International · doi:10.1007/s12072-024-10774-3 · Cited by 200
Plasma Sphingosine-1-Phosphate Is Elevated in Obesity
Kowalski, G. M., Carey, A. L., Selathurai, A., Kingwell, B. A., & Bruce, C. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072449 · Cited by 176
Chomentowski, P., Coen, P. M., Radiková, Z., Goodpaster, B. H., & Toledo, F. G. S. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0822 · Cited by 163
Watt, M. J., Heigenhauser, G. J. F., & Spriet, L. L. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00197.2002 · Cited by 156
Mittendorfer, B., Horowitz, J. F., & Klein, S. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00504.2001 · Cited by 154
Self-citationHuijsman, E., van de Par, C., Economou, C., van der Poel, C., Lynch, G. S., Schoiswohl, G., Haemmerle, G., Zechner, R., & Watt, M. J. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00190.2009 · Cited by 145
Effect of Ramadan fasting on fuel oxidation during exercise in trained male rugby players
Bouhlel, E., Salhi, Z., Bouhlel, H., Mdella, S. B., Amamou, A., Zaouali, M., Mercier, J. G., Bigard, X. A., Tabka, Z., Zbidi, A., et al. (2006) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70317-8 · Cited by 140
Koh, H., Hirshman, M. F., He, H., Li, Y., Manabe, Y., Balschi, J. A., & Goodyear, L. J. (2007) · Biochemical Journal · doi:10.1042/bj20061479 · Cited by 125
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation
Haldar, S. M., Jeyaraj, D., Anand, P., Zhu, H., Lu, Y., Prosdocimo, D. A., Eapen, B. L., Kawanami, D., Okutsu, M., Brotto, L. S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121060109 · Cited by 118
Keating, S. E., Sabag, A., Hallsworth, K., Hickman, I. J., Macdonald, G. A., Stine, J. G., George, J., & Johnson, N. A. (2023) · Sports Medicine · doi:10.1007/s40279-023-01918-w · Cited by 119
Vieira, A., Costa, R. R., Macedo, R. C. O., Coconcelli, L., & Kruel, L. F. M. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516003160 · Cited by 117
Plasma ghrelin levels during exercise — Effects of intensity and duration
Erdmann, J., Tahbaz, R., Lippl, F., Wagenpfeil, S., & SCHUSDZIARRA, V. (2007) · Regulatory Peptides · doi:10.1016/j.regpep.2007.05.002 · Cited by 113
Regulation of Energy Substrate Metabolism in Endurance Exercise
Alghannam, A. F., Ghaith, M. M., & Alhussain, M. H. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18094963 · Cited by 104
Circulating microRNAs in acute and chronic exercise: more than mere biomarkers
Sapp, R. M., Shill, D. D., Roth, S. M., & Hagberg, J. M. (2016) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00982.2016 · Cited by 109
Schmitt, B., Flück, M., Décombaz, J., Kreis, R., Boesch, C., Wittwer, M., Graber, F., Vogt, M., HOWALD, H., & Hoppeler, H. H. (2003) · Physiological Genomics · doi:10.1152/physiolgenomics.00089.2003 · Cited by 103
Davis, R. W. (2013) · Journal of Comparative Physiology B · doi:10.1007/s00360-013-0782-z · Cited by 102
de Groot, R. H. M., Emmett, R., & Meyer, B. J. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519000138 · Cited by 100
Amati, F., Dubé, J. J., Shay, C., & Goodpaster, B. H. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90384.2008 · Cited by 89
Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH
Fredrickson, G., Barrow, F., DIETSCHE, K. B., Parthiban, P., Khan, S. M., Robert, S., Demirchian, M., Rhoades, H., Wang, H., Adeyi, O. A., et al. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101270 · Cited by 91
Exercise and the Treatment of Diabetes and Obesity
O’Gorman, D. J., & Krook, A. (2008) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2008.07.006 · Cited by 88
Immune and Neuroprotective Effects of Physical Activity on the Brain in Depression
Phillips, C., & Fahimi, A. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00498 · Cited by 89
The mitochondrial multi-omic response to exercise training across rat tissues
Amar, D., Gay, N. R., Jimenez‐Morales, D., Beltran, P. M. J., Ramaker, M. E., Raja, A. N., Zhao, B., Sun, Y., Marwaha, S., Gaul, D. A., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2023.12.021 · Cited by 89
Chaiittianan, R., Sutthanut, K., & Rattanathongkom, A. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.02.044 · Cited by 78
ThePPARGC1Agene Gly482Ser in Polish and Russian athletes
Maciejewska, A., Sawczuk, M., Cięszczyk, P., Mozhayskaya, I. A., & Ahmetov, I. I. (2011) · Journal of Sports Sciences · doi:10.1080/02640414.2011.623709 · Cited by 79
Lazzer, S., Vermorel, M., Montaurier, C., Meyer, M., & Boirie, Y. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802977 · Cited by 73
Clegg, M. (2010) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637481003702114 · Cited by 71
Terlouw, C. E. M., & Rybarczyk, P. (2007) · Meat Science · doi:10.1016/j.meatsci.2007.11.013 · Cited by 71
Karl, J. P., Margolis, L. M., Murphy, N. E., Carrigan, C. T., Castellani, J. W., Madslien, E. H., Teien, H. K., Martini, S., Montain, S. J., & Pasiakos, S. M. (2017) · Physiological Reports · doi:10.14814/phy2.13407 · Cited by 68
Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats
Kinman, R., Kasumov, T., Jobbins, K. A., Thomas, K. R., Adams, J. E., Brunengraber, L. N., Kutz, G., Brewer, W. A., Roe, C. R., & Brunengraber, H. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00366.2005 · Cited by 70
Pataky, M. W., Dasari, S., Michie, K. L., Sevits, K. J., Kumar, A., Klaus, K. A., Heppelmann, C. J. H., Robinson, M. M., Carter, R. E., Lanza, I. R., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.10.010 · Cited by 67
Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise
Burniston, J. G. (2008) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2008.04.007 · Cited by 69
Adipose tissue inflammation and metabolic dysfunction: role of exercise.
(2014) · Europe PMC (PubMed Central) · Cited by 67
Reduction of diet-induced obesity by a combination of tea-catechin intake and regular swimming
Murase, T., Haramizu, S., Shimotoyodome, A., & Tokimitsu, I. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803135 · Cited by 66
Toda, K., Hitoe, S., Takeda, S., & Shimoda, H. (2016) · Heliyon · doi:10.1016/j.heliyon.2016.e00115 · Cited by 64
Ohyama, K., Nogusa, Y., Suzuki, K., Shinoda, K., Kajimura, S., & Bannai, M. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00354.2014 · Cited by 65
Decreased Blood Glucose and Lactate: Is a Useful Indicator of Recovery Ability in Athletes?
Yang, W., Park, H., Grau, M., & Heine, O. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17155470 · Cited by 62
Berryman, C. E., Young, A., Karl, J. P., Kenefick, R. W., Margolis, L. M., Cole, R. E., Carbone, J. W., Lieberman, H. R., Kim, I., Ferrando, A. A., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700915r · Cited by 62
Lindner, A., Mosen, H., Kissenbeck, S., Fuhrmann, H., & Sallmann, H. ‐. (2009) · Journal of Animal Science · doi:10.2527/jas.2009-2001 · Cited by 58
Karolkiewicz, J., Michalak, E., Pospieszna, B., Deskur-Śmielecka, E., Nowak, A., & Pilaczyńska-Szczȩśniak, Ł. (2008) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2008.09.001 · Cited by 60
Rottman, J. N., Bracy, D. P., Malabanan, C. M., Yue, Z., Clanton, J., & Wasserman, D. H. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00545.2001 · Cited by 57
Cooper, M. A., Menta, B. W., Pérez-Sánchez, C., Jack, M. M., Khan, Z. W., Ryals, J. M., Winter, M. K., & Wright, D. E. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.05.011 · Cited by 57
The Impact of Exercise on Immunity, Metabolism, and Atherosclerosis
Meyer-Lindemann, U., Moggio, A., Dutsch, A., Kessler, T., & Sager, H. B. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043394 · Cited by 62
Advances in sports food: Sports nutrition, food manufacture, opportunities and challenges
Cui, P., Li, M., Yu, M., Liu, Y., Ding, Y., Liu, W., & Liu, J. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111258 · Cited by 67
Rapid Measurement of Human Milk Macronutrients in the Neonatal Intensive Care Unit
Smilowitz, J. T., Gho, D. S., Mirmiran, M., German, J. B., & Underwood, M. A. (2014) · Journal of Human Lactation · doi:10.1177/0890334413517941 · Cited by 54
Haufe, S., Engeli, S., Budziarek, P., Utz, W., Schulz‐Menger, J., Hermsdorf, M., Wiesner, S., Otto, C., Haas, V. K., de Greiff, A., et al. (2010) · Diabetes · doi:10.2337/db09-1200 · Cited by 55
Effects of Aerobic Training on Gene Expression in Skeletal Muscle of Elderly Men
Radom‐Aizik, S., Hayek, S., Shahar, I., Rechavi, G., Kaminski, N., & Ben-Dov, I. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000181838.96815.4d · Cited by 53
The Physiological and Pathological Role of Acyl-CoA Oxidation
Szrok-Jurga, S., Czumaj, A., Turyn, J., Hebanowska, A., Świerczyński, J., Śledziński, T., & Stelmańska, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914857 · Cited by 58
Basal and Insulin Mediated VLDL-Triglyceride Kinetics in Type 2 Diabetic Men
Sørensen, L. P., Andersen, I. R., Søndergaard, E., Gormsen, L. C., Schmitz, O., Christiansen, J. S., & Nielsen, S. (2010) · Diabetes · doi:10.2337/db10-0564 · Cited by 51
Control of lipolysis by a population of oxytocinergic sympathetic neurons
Li, E., Wang, L., Wang, D., Chi, J., Lin, Z., Smith, G. I., Klein, S., Cohen, P., & Rosen, E. D. (2023) · Nature · doi:10.1038/s41586-023-06830-x · Cited by 49
Self-citationAn 8-Week Ketogenic Low Carbohydrate, High Fat Diet Enhanced Exhaustive Exercise Capacity in Mice
Ma, S., Huang, Q., Yada, K., Liu, C., & Suzuki, K. (2018) · Nutrients · doi:10.3390/nu10060673 · Cited by 50
l -Carnitine enhances exercise endurance capacity by promoting muscle oxidative metabolism in mice
Kim, J. H., Pan, J. H., Lee, E. S., & Kim, Y. J. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.07.009 · Cited by 51
The Warburg Effect: Is it Always an Enemy?
Papaneophytou, C. P. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2912402 · Cited by 49
Influence of Acute and Chronic Exercise on Abdominal Fat Lipolysis: An Update
Laurens, C., de Glisezinski, I., Larrouy, D., Harant, I., & Moro, C. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.575363 · Cited by 52
Effect of the glycaemic index of pre‐exercise carbohydrate meals on running performance
Wong, S. H., Siu, P. M., LOK, A. C. M., Chen, Y. J., Morris, J., & Lam, C. W. (2008) · European Journal of Sport Science · doi:10.1080/17461390701819451 · Cited by 45
Fuxjager, M. J., Lee, J., Chan, T.-M., Bahn, J. H., Chew, J. G., Xiao, X. G., & Schlinger, B. A. (2016) · Molecular Endocrinology · doi:10.1210/me.2015-1270 · Cited by 45
Hypoxic Training Improves Normoxic Glucose Tolerance in Adolescents with Obesity
Groote, E. D., Britto, F. A., Bullock, L. P., FRANÇOIS, M., Buck, C. D., Nielens, H., & Deldicque, L. (2018) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001694 · Cited by 45
Santos, S. S., Moreira, J. B., Costa, M., Rodrigues, R. S., Sebastião, A. M., Xapelli, S., & Solá, S. (2021) · Cells · doi:10.3390/cells11010090 · Cited by 44
Exercise and the Treatment of Diabetes and Obesity
O’Gorman, D. J., & Krook, A. (2011) · Medical Clinics of North America · doi:10.1016/j.mcna.2011.06.007 · Cited by 44
Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle
Long, Y. C., & Zierath, J. R. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90259.2008 · Cited by 41
Macdermid, P. W., & Stannard, S. R. (2006) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.16.1.65 · Cited by 41
Fat metabolism in exercise – with special reference to training and growth hormone administration
Lange, K. H. W. (2004) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2004.381.x · Cited by 40
An “Exercise” in Cardiac Metabolism
Kolwicz, S. C. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00066 · Cited by 42
Oh, K. S., Kim, E. Y., Yoon, M., & Lee, C. M. (2007) · Experimental & Molecular Medicine · doi:10.1038/emm.2007.43 · Cited by 39
Ojuka, E. O., Andrew, B., Bezuidenhout, N., George, S., Maarman, G. J., Madlala, H. P., Mendham, A. E., & Osiki, P. O. (2016) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00475.2015 · Cited by 37
Pre-season dietary intake of professional soccer players
Raizel, R., Godois, A. D. M., Coqueiro, A. Y., Voltarelli, F. A., Fett, C. A., Tirapegui, J., Ravagnani, F. C. D. P., & Coelho‐Ravagnani, C. D. F. (2017) · Nutrition and Health · doi:10.1177/0260106017737014 · Cited by 36
Fujita, H., Shimizu, K., & Nagamori, E. (2010) · Biotechnology and Bioengineering · doi:10.1002/bit.22705 · Cited by 37
Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Fernandez, C., Hansson, O., Nevsten, P., Holm, C., & Klint, C. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00282.2007 · Cited by 36
Nosaka, N., Suzuki, Y., Nagatoishi, A., Kasai, M., Jian, W. U., & Taguchi, M. (2009) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.55.120 · Cited by 35
Vaughan, D. A., Brogioli, M., Maier, T., White, A., Waldron, S., Rittweger, J., Toigo, M., Wettstein, J., Laczkó, E., & Flück, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149046 · Cited by 34
Hörer, T. M., Norgren, L., & Jansson, K. (2011) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2011.568519 · Cited by 33
Eckstein, M. L., Williams, D. M., O'Neil, L., Hayes, J., Stephens, J. W., & Bracken, R. M. (2018) · Diabetic Medicine · doi:10.1111/dme.13865 · Cited by 34
Erdmann, J., Leibl, M., Wagenpfeil, S., Lippl, F., & SCHUSDZIARRA, V. (2006) · Regulatory Peptides · doi:10.1016/j.regpep.2006.03.003 · Cited by 33
Badawy, A. A. ‐. (2018) · International Journal of Tryptophan Research · doi:10.1177/1178646917753422 · Cited by 33
Sinaei, M., & Zare, R. (2019) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2019.06.024 · Cited by 32
Javelle, F., Bloch, W., Knoop, A., Guillemin, G. J., & Zimmer, P. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.04.020 · Cited by 35
Maximal Physiological Responses between Aquatic and Land Exercise in Overweight Women
PHILLIPS, V. K., Legge, M., & Jones, L. M. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318164d0e0 · Cited by 33
Christensen, B., Nellemann, B., Larsen, M. S., Thams, L., Sieljacks, P., Vestergaard, P. F., Bibby, B. M., Vissing, K., Stødkilde‐Jørgensen, H., Pedersen, S. B., et al. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00269.2013 · Cited by 31
Ooyama, K., Jian, W. U., Nosaka, N., AOYAMA, T., & Kasai, M. (2008) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.54.136 · Cited by 31
Tinius, R. A., Cahill, A. G., Strand, E. A., & Cade, W. T. (2015) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0316 · Cited by 29
Yanina, I. Y., Tuchin, V. V., Наволокин, Н. А., Matveeva, O. V., Bucharskaya, A. B., Maslyakova, G. N., & Altshuler, G. B. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.5.058002 · Cited by 29
Wen, D., Zheng, L., Li, J., Lǚ, K., & Hou, W.-Q. (2019) · Aging · doi:10.18632/aging.102261 · Cited by 29
Effects of endurance exercise on the urinary proteome analyzed by 2‐D PAGE and Orbitrap MS
Kohler, M., Walpurgis, K., Thomas, A., de Maree, M., Mester, J., Schänzer, W., & Thevis, M. (2010) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200900209 · Cited by 29
Acylation-stimulating protein: effect of acute exercise and endurance training
Schrauwen, P., Hesselink, M. K. C., Jain, M. D., & Cianflone, K. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802949 · Cited by 29
Priority use of medium-chain fatty acids during high-intensity exercise in cross-country skiers
Lyudinina, A. Y., Ivankova, G. E., & Bojko, E. R. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0265-4 · Cited by 27
Metadata
- Authors
- Horowitz, J. F., & Klein, S.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 72
- Issue
- 2
- Pages
- 558S-563S
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2170377446
- Cited by
- 397
- References
- 76
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 17 · 2023: 18 · 2022: 22 · 2021: 24 · 2020: 28 · 2019: 16 · 2018: 18 · 2017: 14 · 2016: 23 · 2015: 22 · 2014: 20 · 2013: 11 · 2012: 14
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5p41rr000954-34)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK37948, R01DK037948)
- National Center for Research Resources (RR 00954, RR0036)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Keywords
- lipid metabolism, endurance exercise, triacylglycerol oxidation, fat oxidation, lipolysis, fatty acid mobilization, adipose tissue, catecholamines, endurance training, exercise intensity, lipid supplementation, medium-chain triglycerides, long-chain triglycerides, skeletal muscle
- MeSH terms
- Adipose Tissue, Exercise Test, Fatty Acids, Humans, Lipolysis, Mitochondria, Physical Endurance, Physical Fitness, Triglycerides, Exercise, Muscle, Skeletal, Dietary Supplements
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
