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Collagen Biosynthesis, Processing, and Maturation in Lung Ageing

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The liver matrisome – looking beyond collagens

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Clinical/Translational Aspects of Advanced Glycation End-Products

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Polyphenols and AGEs/RAGE axis. Trends and challenges

González, I., Morales, M. A., & Armando Rojas, R. (2019) · Food Research International · doi:10.1016/j.foodres.2019.108843 · Cited by 101 · see citing works

Gastric Tumor Microenvironment

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The Role of Sarcopenic Obesity in Cancer and Cardiovascular Disease: A Synthesis of the Evidence on Pathophysiological Aspects and Clinical Implications

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The RAGE Axis: A Relevant Inflammatory Hub in Human Diseases

Armando Rojas, R., Lindner, C., Schneider, I., González, I., & Uribarri, J. (2024) · Biomolecules · doi:10.3390/biom14040412 · Cited by 53 · see citing works

AGEs and RAGE: metabolic and molecular signatures of the glycation-inflammation axis in malignant or metastatic cancers

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The potential role of dietary advanced glycation endproducts in the development of chronic non-infectious diseases: a narrative review

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Leveling Up the Controversial Role of Neutrophils in Cancer: When the Complexity Becomes Entangled

Sionov, R. V. (2021) · Cells · doi:10.3390/cells10092486 · Cited by 42 · see citing works

AGEing of collagen: The effects of glycation on collagen’s stability, mechanics and assembly

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Fibrous stroma: Driver and passenger in cancer development

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Type 2 Diabetes Mellitus and Cancer: Epidemiology, Physiopathology and Prevention

Rey‐Reñones, C., Baena-Díez, J. M., Aguilar‐Palacio, I., Miquel, C., & Grau, M. (2021) · Biomedicines · doi:10.3390/biomedicines9101429 · Cited by 41 · see citing works

Exploring the Interplay between Polyphenols and Lysyl Oxidase Enzymes for Maintaining Extracellular Matrix Homeostasis

Añazco, C. C., Riedelsberger, J., Vega‐Montoto, L., & Armando Rojas, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310985 · Cited by 38 · see citing works

Inhibition of RAGE Axis Signaling: A Pharmacological Challenge

Armando Rojas, R., Morales, M. A., González, I., & Araya, P. (2018) · Current Drug Targets · doi:10.2174/1389450119666180820105956 · Cited by 31 · see citing works

Skin autofluorescence predicts cancer in subjects with type 2 diabetes

Foussard, N., Larroumet, A., Rigo, M., Mohammedi, K., Baillet‐Blanco, L., Poupon, P., Monlun, M., Lecocq, M., Devouge, A., Ducos, C., et al. (2021) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2020-001312 · Cited by 29 · see citing works

The cardiovascular complications of diabetes: a striking link through protein glycation

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The RAGE/multiligand axis: a new actor in tumor biology

Armando Rojas, R., Schneider, I., Lindner, C., González, I., & Morales, M. A. (2022) · Bioscience Reports · doi:10.1042/bsr20220395 · Cited by 23 · see citing works

Contribution of RAGE axis activation to the association between metabolic syndrome and cancer

Garay‐Sevilla, M. E., Gómez-Ojeda, A., González, I., Luévano‐Contreras, C., & Armando Rojas, R. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-04022-z · Cited by 22 · see citing works

Recent advances in histone glycation: emerging role in diabetes and cancer

Mir, A. R., Habib, S., & Uddin, M. (2021) · Glycobiology · doi:10.1093/glycob/cwab011 · Cited by 20 · see citing works

Methylglyoxal-derived advanced glycation end products induce matrix metalloproteinases through activation of ERK/JNK/NF-κB pathway in kidney proximal epithelial cells

Jeong, S.-R., Park, H., Kim, Y., & Lee, K. (2019) · Food Science and Biotechnology · doi:10.1007/s10068-019-00704-7 · Cited by 19 · see citing works

Pathophysiological Characteristics Linking Type 2 Diabetes Mellitus and Colorectal Neoplasia

Grega, T., Vojtěchová, G., Gregová, M., Zavoral, M., & Suchánek, Š. (2021) · Physiological Research · doi:10.33549/physiolres.934631 · Cited by 18 · see citing works

The RAGE/DIAPH1 axis: mediator of obesity and proposed biomarker of human cardiometabolic disease

Arivazhagan, L., Popp, C. J., Ruiz, H. H., Wilson, R. A., Manigrasso, M. B., Shekhtman, A. G., Ramasamy, R., Sevick, M. A., & Schmidt, A. M. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac175 · Cited by 15 · see citing works

Mice with Type 2 Diabetes Present Significant Alterations in Their Tissue Biomechanical Properties and Histological Features

Cruz, T., Carvalho, F. A., Matafome, P. N., Soares, R. A., Santos, N. C., Travasso, R. D. M., & Oliveira, M. J. (2021) · Biomedicines · doi:10.3390/biomedicines10010057 · Cited by 15 · see citing works

Light in evaluation of molecular diffusion in tissues: Discrimination of pathologies

Oliveira, L. R., Pinheiro, M. R., Tuchina, D. K., Dyachenko, P. A., Carvalho, M. I., & Oliveira, L. M. C. (2024) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2024.115420 · Cited by 14 · see citing works

Shorter Telomere Length in Carriers of APOE-ε4 and High Plasma Concentration of Glucose, Glyoxal and Other Advanced Glycation End Products (AGEs)

Dhillon, V. S., Deo, P., Chua, A., Thomas, P., & Fenech, M. F. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz203 · Cited by 14 · see citing works

Association between diabetes and cancer. Current mechanistic insights into the association and future challenges

Armando Rojas, R., Schneider, I., Lindner, C., González, I., & Morales, M. A. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04630-x · Cited by 13 · see citing works

Pathological role of RAGE underlying progression of various diseases: its potential as biomarker and therapeutic target

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Long-Term Local Injection of RAGE-Aptamer Suppresses the Growth of Malignant Melanoma in Nude Mice

Nakamura, N., Matsui, T., Nishino, Y., Sotokawauchi, A., Higashimoto, Y., & Yamagishi, S. (2019) · Journal of Oncology · doi:10.1155/2019/7387601 · Cited by 13 · see citing works

Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer

Armando Rojas, R., Lindner, C., Schneider, I., González, I., Araya, H., Morales, E., Gómez, M., Nelson Urdaneta, L., Araya, P., & Morales, M. A. (2021) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v13.i12.1997 · Cited by 12 · see citing works

Skin autofluorescence of Advanced Glycation End-products and mortality in older adults: The roles of chronic kidney disease and diabetes

Majchrzak, C., Cougnard‐Grégoire, A., Goff, M. L., Féart, C., Delcourt, C., Prezelin‐Reydit, M., Helmer, C., & Rigalleau, V. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.08.009 · Cited by 12 · see citing works

Therapeutic Potential of Pigment Epithelium-derived Factor in Cancer

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Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer

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A review of the last decade: pancreatic cancer and type 2 diabetes

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Detrimental effects of advanced glycation end-products (AGEs) on a 3D skeletal muscle model in microphysiological system

Kim, J.-S., Kim, I. U., Lee, Z. F., Han, J., Ahn, J., Jo, Y., Kim, P., Yoo, H., Sim, G., & Jeon, J. S. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117316 · Cited by 9 · see citing works

Quantitatively Assessing the Respiratory Burst in Innate Immune Cells

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Advanced glycation end products of bovine serum albumin affect the cell growth of human umbilical vein endothelial cells via modulation of MEG3/miR-93/p21 pathway

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Emerging and multifaceted potential contributions of polyphenols in the management of type 2 diabetes mellitus

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The Antiglycation Effect of Monomethyl Branched Chained Fatty Acid and Phytochemical Compounds and their Synergistic Effect on Obesity Related Colorectal Cancer Cell Panel

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Salivary Gland Bioengineering

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The impact of sarcopenic obesity on cancer clinical outcomes

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Mimicking Gastric Cancer Collagen Reorganization with Decellularized ECM-Based Scaffolds

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T2DM may exert a protective effect against digestive system tumors in East Asian populations: a Mendelian randomization analysis

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Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

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1,25(OH)2D3 inhibits pancreatic stellate cells activation and promotes insulin secretion in T2DM

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Anti-aging effect of polyphenols: possibilities and challenges

Chaiwangyen, W., Chumphukam, O., Kangwan, N., Pintha, K., & Suttajit, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90581-7.00022-0 · Cited by 6 · see citing works

Advanced Glycation End Products and Diabetes

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Advanced glycation end product (AGE) targeting antibody SIWA318H is efficacious in preclinical models for pancreatic cancer

Rossi, G. R., Jensen, A., Ng, S., Yin, Z., Li, A., Misra, A., Hoff, D. D. V., Gruber, L., Gruber, M., & Han, H. (2023) · Scientific Reports · doi:10.1038/s41598-023-44211-6 · Cited by 5 · see citing works

Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer

Pathak, C., Vaidya, F. U., Waghela, B. N., Chhipa, A. S., Tiwari, B. S., & Ranjan, K. (2022) · Springer eBooks · doi:10.1007/978-981-15-9411-3_44 · Cited by 7 · see citing works

Common miRNAs , Genes, and Regulatory Pathways in Alzheimer's Disease and Type 2 Diabetes Mellitus: An Integrative Analysis of Systematic Reviews, Bioinformatics and Data Mining

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Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights

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Pre‐diagnostic plasma advanced glycation end‐products and soluble receptor for advanced glycation end‐products and mortality in colorectal cancer patients

Li, J., Baker, J. R., Aglago, E. K., Zhao, Z., Jiao, L., Freisling, H., Hughes, D. J., Eriksen, A. K., Tjønneland, A. M., Severi, G., et al. (2024) · International Journal of Cancer · doi:10.1002/ijc.35114 · Cited by 3 · see citing works

Advanced Glycation End Products Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer

Pathak, C., Vaidya, F. U., Waghela, B. N., Chhipa, A. S., Tiwari, B. S., & Ranjan, K. (2021) · Springer eBooks · doi:10.1007/978-981-15-4501-6_44-1 · Cited by 3 · see citing works

Advanced Glycation End Products in Diabetes

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Receptor of advanced glycation end-products axis and gallbladder cancer: A forgotten connection that we should reconsider

Armando Rojas, R., Lindner, C., Schneider, I., González, I., & Morales, M. A. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i39.5679 · Cited by 3 · see citing works

RAGE-Dependent Effect of Exogenous Methylglyoxal Intake on Lung Biomechanics in Mice

Al‐Robaiy, S., Santos, A. N., & Simm, A. (2022) · Nutrients · doi:10.3390/nu15010023 · Cited by 3 · see citing works

Antiglycation and chemopreventive effects of leaf extracts of Ficus palmata Forssk. found in the Hail region of Saudi Arabia

Alouffi, S., Maarfi, F., Khan, M. Y., Khan, S. A., Khan, M. S., & Ahmad, S. (2023) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2023.2196477 · Cited by 3 · see citing works

Role of polyphenols in modulating AGEs-RAGE axis in cancer, a review

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Current Trends in Non-Invasive Imaging of Interactions in the Liver Tumor Microenvironment Mediated by Tumor Metabolism

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Lung cancer and diabetes: A role for advanced glycation end‐products?

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The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes MellitusPreprint

González, I., Lindner, C., Schneider, I., Díaz-Bautista, E., Morales, M. A., & Armando Rojas, R. (2023) · Preprints.org · doi:10.20944/preprints202307.0110.v1 · Cited by 2 · see citing works

Is there a link between fascia and cancer? From potential mechanisms to future treatment options

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Aging promotes a RAGE-dependent increase in breast cancer metastasis

Miller, P., Chopra, S., Magna, M., Tao, J., Benitez, C., Heist, T., Bishopric, N. H., Mandelblatt, J. S., Panov, J., Slingerland, J. M., et al. (2026) · Communications Biology · doi:10.1038/s42003-026-10022-4 · Cited by 1 · see citing works

Advanced Glycation End Products in Diabetes

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Comment on Sjöholm et al. Association of Bariatric Surgery With Cancer Incidence in Patients With Obesity and Diabetes: Long-term Results From the Swedish Obese Subjects Study. Diabetes Care 2022;45:444–450

Rigalleau, V., Barbet‐Massin, M., Larroumet, A., Mohammedi, K., Baillet‐Blanco, L., Monlun, M., Cherifi, B. G., & Foussard, N. (2022) · Diabetes Care · doi:10.2337/dc21-2477 · Cited by 1 · see citing works

Antioxidant activities of underexplored Chinese medicinal plant parts and their effect against high glucose-induced modulation of fibronectin expression

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Avaliação da estrutura e síntese da matriz extracelular do tecido cutâneo em pacientes diabéticos

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Glucose metabolism disorders in cancer patients

Różycka, K., & Kapała, A. (2023) · Nowotwory Journal of Oncology · doi:10.5603/njo.a2023.0034

Les AGE (produits terminaux de glycation) : attention danger. Origine, effets toxiques et stratégies thérapeutiques

Portha, B., & Liu, J. (2023) · Cahiers de Nutrition et de Diététique · doi:10.1016/j.cnd.2023.10.001

GELİŞMİŞ GLİKASYON SON ÜRÜNLERİ VE SAĞLIK ÜZERİNE ETKİSİ

Korkmaz, Y., & Gücükoğlu, A. (2024) · Samsun Sağlık Bilimleri Dergisi · doi:10.47115/jshs.1326266

C2-α-dicarbonyls selectively impair morphodynamic interactions between cells and extracellular matrixPreprint

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Hypothesis and Evidence: Immune CellTherapy Might Yield Poor Outcomes in Patients with Diabetes

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Deciphering radiopharmaceutical mechanisms through integrated proteomic and PTM-proteomic profiling

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Glycation Product Synthesized in Anhydrous Conditions Mimics an Epitope in Epithelial and Mesenchymal Tissues

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Metabolic reprogramming and epigenetic effects due to reducing sugars and glycation products in cancer

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Implication of the receptor for advanced glycation end-products (RAGE) during inflammation and ageing

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Nanophysical and pharmacological approaches to modulate tumor stiffness, extracellular matrix organization and immune response of solid tumors

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Using digital holographic microscopy (DHM) to monitor effects of extracellular matrix (ECM) glycation on cancer cell morphology and migrationPreprint

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Metabolic convergence of diabetes and prostate cancer: from dysglycemia to tumor microenvironment reprogramming

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Extracellular matrix glycation and RAGE activation. A missing piece in the puzzle of the association between diabetes and cancer

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Implications of receptor for advanced glycation end products for progression from obesity to diabetes and from diabetes to cancer

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Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening

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Role of Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Cancer Risk

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The advanced glycation end‐product Nϵ‐carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes‐associated risk and its prevention

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