Temporal dissociation of early lexical access and articulation using a delayed naming task—an FMRI study
Abstract
Neuroimaging studies of overt speech hold an important practical advantage allowing monitoring of subject performance, particularly valuable in disorders like aphasia. However, speech production is not a monotonic process but a complex sequence of stages. Levelt and colleagues have described these as roughly corresponding to two originally independent systems--conceptual and sensorimotor--that are linked in the formulation and expression of spoken language. In the initial stages a word is chosen to match a concept (lexical selection); in the later stages the sound and motor patterns are encoded and the word is uttered (articulation). It has been difficult to discriminate these stages using conventional neuroimaging techniques. We designed a functional magnetic resonance imaging study in an attempt to do this, by introducing a latency into a conventional naming paradigm, delaying the articulated response. Our results showed that left hemisphere perisylvian areas were active throughout, interacting with visual and heteromodal areas during early lexical access and with motor and auditory areas during overt articulation. These results are consistent with the broadest version of the Levelt model and with that derived from Chomsky's minimalist program in which a core language system interacts with conceptual-intentional systems and articulatory-perceptual systems during the early and late stages of lexical access respectively.
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The SMA is commonly activated by word generation and reading when articulation is matched.
“This distinction was supported by observations that the SMA was commonly activated by word generation and reading when articulation was matched but the pre-SMA was more activated by: (a) word generation than reading, (Chung et al., 2005; Tremblay and Gracco, 2006;), (b) during the covert rather than overt stage of object and action naming (Kemeny et al., 2006), and (c) pseudoword repetition when”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Kemeny et al., 2006
The pre-SMA is more activated during the covert rather than overt stage of object and action naming.
“(b) during the covert rather than overt stage of object and action naming (Kemeny et al., 2006)”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Kemeny et al., 2006
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- Authors
- Kemeny, S., Xu, J., Park, G. H., Hosey, L. A., Wettig, C. M., & Braun, A. R.
- Affiliations
- National Institutes of Health (US)
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-07-27
- Volume
- 16
- Issue
- 4
- Pages
- 587-595
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- OpenAlex
- W2165269353
- Cited by
- 58
- References
- 45
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 3 · 2017: 6 · 2016: 3 · 2015: 3 · 2014: 1 · 2013: 3 · 2012: 3
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cerebral Cortex (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
- Social Sciences › Psychology › Developmental and Educational Psychology › Language Development and Disorders
- Keywords
- lexical access, speech articulation, perisylvian cortex, left hemisphere, auditory cortex, motor cortex, visual cortex, aphasia, Minimalist Program
- MeSH terms
- Adult, Brain Mapping, Cerebral Cortex, Concept Formation, Evoked Potentials, Humans, Language, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual, Reaction Time, Semantics, Speech
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