World Gastroenterology Organisation Global Guidelines: Probiotics and Prebiotics October 2011
Abstract
Guarner, Francisco MD (Chair, Spain); Khan, Aamir G. MD (Pakistan); Garisch, James MD (South Africa); Eliakim, Rami MD (Israel); Gangl, Alfred MD (Austria); Thomson, Alan MD (Canada); Krabshuis, Justus (France); Lemair, Ton MD (The Netherlands); Kaufmann, Pedro MD (Uruguay); de Paula, Juan Andres MD (Argentina); Fedorak, Richard MD (Canada); Shanahan, Fergus MD (Ireland); Sanders, Mary Ellen PhD (USA); Szajewska, Hania MD (Poland); Ramakrishna, Balakrishnan Siddartha MD (India); Karakan, Tarkan MD (Turkey); Kim, Nayoung MD (South Korea) Review Team Invited outside experts Author Information
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Most microorganisms currently recognized as probiotics belong to the LAB group.
“Most microorganisms currently recognized as probiotics belong to the LAB group [201,202,214].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [202]
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“There are different mechanisms of action through which probiotics and prebiotics can impact human health such as inhibition of pathogenic bacteria, immunomodulatory effects, stimulation of barrier function and metabolic function (Guarner et al. 2012).”
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“[13] [14] A wellcharacterized probiotic should be defined clearly by the genus, species, and strain designation, as well as indicate the microbiological culture conditions.”
World Gastroenterology Organisation Global Guidelines: Probiotics and Prebiotics
Guarner, F., Sanders, M. E., Szajewska, H., Cohen, H., Eliakim, R., Herrera-deGuise, C., Karakan, T., Merenstein, D., Piscoya, A., Ramakrishna, B., et al. (2024) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000002002 · Cited by 209 · see citing works
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“…easily inferred by shifts in the configuration of microbiota; little information exists describing how different modes of administration and particular bacterial strains influence health outcomes; and dose-response guidelines only exist for GI disorders (Guarner et al., 2012; Kristensen et al., 2016).”
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Marín-Manzano, M. C., Abecia, L., Hernández-Hernández, O., Sanz, M. L., Montilla, A., Olano, A., Rubio, L. A., Moreno, F. J., & Clemente, A. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf402218z · Cited by 69 · see citing works
Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide
Mazzantini, D., Calvigioni, M., Celandroni, F., Lupetti, A., & Ghelardi, E. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.693973 · Cited by 70 · see citing works
Effect of probiotics on oral candidiasis: a systematic review and meta-analysis
Mundula, T., Ricci, F., Barbetta, B., Baccini, M., & Amedei, A. (2019) · Nutrients · doi:10.3390/nu11102449 · Cited by 68 · see citing works
“The beneficial proprieties of probiotics are supported by various in vitro and in vivo studies, which used different bacterial strains (single or in combination), at different dosages [31,32].”
BackgroundFunctional yogurt: a comprehensive review of its nutritional composition and health benefits
Pannerchelvan, S., Rios‐Solis, L., Wasoh, H., Sobri, Z. M., Wong, F. W. F., Mohamed, M. S., Mohamad, R., & Halim, M. (2024) · Food & Function · doi:10.1039/d4fo03671a · Cited by 75 · see citing works
“This is because until now, only two probiotics which are rhamnosus GG and S. boulardii have been proven to be able to treat AAD in both young and adult patients (Guarner et al., 2012).”
Haghshenas, B., Nami, Y., Abdullah, N., Biak, D. R. A., Rosli, R., & Khosroushahi, A. Y. (2014) · LWT · doi:10.1016/j.lwt.2014.09.058 · Cited by 68 · see citing works
Probiotics as regulators of inflammation: A review
Lescheid, D. W. (2014) · Functional Foods in Health and Disease · doi:10.31989/ffhd.v4i7.2 · Cited by 67 · see citing works
Radlović, N., Leković, Z., Vuletić, B., Radlović, V., & Simić, D. (2015) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh1512755r · Cited by 70 · see citing works
“Probiotics, racecadotril and diosmectite have a favorable effect on the clinical course of the disease [4, 5, 37, 47, 48].”
Recommendations for Probiotic Use in Humans—A 2014 Update
Floch, M. H. (2014) · Pharmaceuticals · doi:10.3390/ph7100999 · Cited by 62 · see citing works
Role of probiotics in prevention and treatment of enteric infections: a comprehensive review
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Dinleyici, E. Ç., Dalgıç, N., Güven, Ş., Özen, M., Kara, A., Arıca, V., Timur, Ö. M., Sancar, M., Kurugöl, Z., Tanır, G., et al. (2012) · European Journal of Pediatrics · doi:10.1007/s00431-012-1903-5 · Cited by 63 · see citing works
Zalewski, B., Patro-Gołąb, B., Veldhorst, M. A. B., Kouwenhoven, S. M. P., Escobar, P. C., Calvo‐Lerma, J., Koletzko, B. V., van Goudoever, J. B., & Szajewska, H. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.888701 · Cited by 62 · see citing works
Self-citationBacillus clausii and gut homeostasis: state of the art and future perspectives
Lopetuso, L. R., Scaldaferri, F., Franceschi, F., & Gasbarrini, A. (2016) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2016.1200465 · Cited by 66 · see citing works
Azagra-Boronat, I., Massot‐Cladera, M., Knipping, K., Garssen, J., Amor, K. B., Knol, J., Franch, À., Castell, M., Rodríguez-Lagunas, M. J., & Pérez-Cano, F. J. (2020) · Nutrients · doi:10.3390/nu12020498 · Cited by 62 · see citing works
Safeguarding of quinoa beverage production by fermentation with Lactobacillus plantarum DSM 9843
Canaviri-Paz, P., Janny, R. J., & Håkansson, Å. (2020) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2020.108630 · Cited by 64 · see citing works
Awareness, Knowledge, and Interest about Prebiotics—A Study among Romanian Consumers
Precup, G., Pocol, C. B., Teleky, B., & Vodnar, D. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031208 · Cited by 63 · see citing works
- Authors
- Guarner, F., Khan, A. G., Garisch, J., Eliakim, R., Gangl, A., Thomson, A., Krabshuis, J., Lemair, T., Kaufmann, P., de Paula, J. A., Fedorak, R., Shanahan, F., Sanders, M. E., Szajewska, H., Ramakrishna, B. S., Karakan, T., & Kim, N.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- Vall d'Hebron Hospital Universitari (ES)
- ORCID
- Venue
- Journal of Clinical Gastroenterology
- Published
- 2012-07
- Volume
- 46
- Issue
- 6
- Pages
- 468-481
- ISSN
- 0192-0790 (ISSN-L)
- OpenAlex
- W1975779288
- Cited by
- 418
- References
- 0
- Citations by year
- 2026: 6 · 2025: 16 · 2024: 26 · 2023: 36 · 2022: 39 · 2021: 45 · 2020: 48 · 2019: 32 · 2018: 27 · 2017: 27 · 2016: 30 · 2015: 33 · 2014: 28 · 2013: 19 · 2012: 6
- FWCI
- 26.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Keywords
- World Gastroenterology Organisation, gastroenterology
- MeSH terms
- Adult, Animals, Child, Gastroenterology, Gastrointestinal Diseases, Humans, Evidence-Based Medicine, Probiotics, Gastrointestinal Tract, Prebiotics
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