CoChat
Sign Up
Cited by 186Probiotics and Fermented FoodsReproductive tract infections researchInfections and bacterial resistance

Lactobacilli and Bacteremia in Southern Finland, 1989-1992

Saxelin, M., Chuang, N.-H., Chassy, B., Rautelin, H., Makela, P. H., Salminen, S., Gorbach, S. L.·1996·Clinical Infectious Diseases
DOI 10.1093/clinids/22.3.564
Open this paper in CoChat — free account

Abstract

In order to assess the potential of lactobacilli to cause serious infections, we studied the prevalence of bacteremia due to Lactobacillus species during a 4-year period (1989-1992) in southern Finland, which has a population of about 2.5 million. Among 3,317 blood culture isolates, lactobacilli were identified in eight patients, five of whom had a severe disease predisposing to bacteremic complications. The eight strains isolated were identified to the species level and typed by carbohydrate fermentation tests and by direct sequencing of enzymatically amplified 16S rRNA. The results did not provide evidence that any particular species or subspecies of Lactobacillus was the cause of the infections; no infections caused by isolates similar to the recently introduced dairy probiotic strain, Lactobacillus GG (ATCC 53103), were observed. The data show an infrequent association of lactobacilli with bacteremic infections in spite of the ubiquitous presence of these organisms in the gastrointestinal tract and their widespread consumption in fermented milks; thus, there is strong evidence that their pathogenic potential is very low.

Integrity signals

Registry

Crossref · 10.1093/clinids/22.3.564

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The prevalence of LB is 0.1-0.2% of all isolates identified in blood cultures from hospitalized patients and 0.5% of blood isolates from immunocompromised patients.

    “The prevalence of LB is generally low, comprising 0.1–0.2% of all isolates identified in blood cultures from hospitalized patients and 0.5% of blood isolates from immunocompromised patients [2,10,18,19,20].”

    From Lactobacillus Bacteremia and Probiotics: A Review (2023) · cites this paper as [19]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Saxelin, M., Chuang, N.-H., Chassy, B., Rautelin, H., Makela, P. H., Salminen, S., & Gorbach, S. L.
Affiliations
  • University of Turku (FI)
  • Tufts University (US)
ORCID
Venue
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Published
1996-03-01
Volume
22
Issue
3
Pages
564-566
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
DOI
10.1093/clinids/22.3.564
OpenAlex
W2068824740
Cited by
186
References
12
Citations by year
2025: 1 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 5 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 5 · 2014: 2 · 2013: 6 · 2012: 6
FWCI
23.75
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Infections and bacterial resistance
Keywords
Lactobacillus, bacteremia, blood culture isolates, 16S rRNA gene sequencing, Lactobacillus rhamnosus GG, fermented milk, probiotics, gastrointestinal tract colonization, southern Finland
MeSH terms
Adult, Aged, Female, Finland, Humans, Lactobacillus, Male, Middle Aged, RNA, Ribosomal, 16S, Bacteremia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review