Human gut microbiota and its relationship to health and disease: Nutrition Reviews©, Vol. 69, No. 7
Abstract
Probiotics are live microorganisms that confer a health benefit on the host when administered in appropriate amounts. Over 700 randomized, controlled, human studies have been conducted with probiotics thus far, with the results providing strong support for the use of probiotics in the clinical prevention or treatment of gastrointestinal tract disorders and metabolic syndrome. The present review is based on webinar presentations that were developed by the American Gastroenterological Association (AGA) in partnership with the International Scientific Association for Probiotics and Prebiotics (ISAPP) and the North American branch of the International Life Sciences Institute (ILSI North America). The presentations provided gastroenterologists and researchers with fundamental and current scientific information on the influence of gut microbiota on human health and disease, as well as clinical intervention strategies and practical guidelines for the use of probiotics and prebiotics.
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Abnormal diversity (dysbiosis) in the gut has been proven to be associated with human diseases such as obesity, inflammatory bowel disease, and cancer.
“Abnormal diversity (dysbiosis) in the gut has been proven to be associated with human diseases, such as obesity, inflammatory bowel disease, cancer, etc. 20,21,33,34”
From The Diversity of Gut Microbiome is Associated With Favorable Responses to Anti–Programmed Death 1 Immunotherapy in Chinese Patients With NSCLC (2019) · cites this paper as [21]
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- Authors
- Wallace, T. C., Guarner, F., Madsen, K., Cabana, M. D., Gibson, G., Hentges, E., & Sanders, M. E.
- Affiliations
- International Life Sciences Institute (US)
- Vall d'Hebron Hospital Universitari (ES)
- University of Alberta (CA)
- University of California, San Francisco (US)
- University of Reading (GB)
- ORCID
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-06-30
- Volume
- 69
- Issue
- 7
- Pages
- 392-403
- ISSN
- 0029-6643 (ISSN-L)
- OpenAlex
- W2128873562
- Cited by
- 234
- References
- 6
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 13 · 2023: 8 · 2022: 13 · 2021: 20 · 2020: 13 · 2019: 12 · 2018: 18 · 2017: 13 · 2016: 14 · 2015: 18 · 2014: 31 · 2013: 33 · 2012: 20
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- gut microbiota, probiotics, prebiotics, gastrointestinal diseases, metabolic syndrome, clinical prevention, clinical management
- MeSH terms
- Animals, Gastrointestinal Diseases, Health Status, Humans, Practice Guidelines as Topic, Probiotics, Metabolic Syndrome, Prebiotics
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