Safety aspects of probiotic products
Open accessAbstract
Probiotics (i.e. ingested living microorganisms) may theoretically be responsible for four types of side effects: systemic infections, deleterious metabolic activities, excessive immune stimulation in susceptible individuals, and gene transfer. Very few cases of adverse events have been reported in humans consuming probiotics, and these are summarized in this paper. I also briefly summarize the three approaches which can be used to assess the safety of a probiotic strain: studies on the intrinsic properties of the strain, studies on its pharmacokinetics, and studies searching for interactions between the strain and the host. Key words: Bifidobacterium, Lactobacillus, probiotics, safety, side effects
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Four classes of possible side effects of probiotic use are systemic infections, detrimental metabolic effects, cytokine-mediated immunologic adverse events in susceptible individuals, and transfer of antibiotic resistance genes.
“Marteau [214] outlined four classes of possible side effects of probiotic use: systemic infections, detrimental metabolic effects, cytokine-mediated immunologic adverse events in susceptible individuals, and transfer of antibiotic resistance genes.”
From International Society of Sports Nutrition Position Stand: Probiotics (2019) · cites this paper as [214]
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Probiotic Foods and Dietary Supplements
Msagati, T. A. M. (2012) · doi:10.1002/9781118274132.ch18
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Therapeutic Manipulation of Gut Microbiota
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ASSESSING YOGURT FERMENTATION ABILITY FROM COW MILK ADDED SOURSOP PUREE
Pham, N. B., Thai, H. M., & Pham, D. T. C. (2018) · Scientific Journal of Tra Vinh University · doi:10.35382/18594816.1.32.2018.61
Sun, Y. (2020) · Tuwhera (Auckland University of Technology)
IMPROVEMENT OF THE TECHNOLOGY OF FISH PUDDING FOR INFANT NUTRITION
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Influence of Fermented Food Derived Probiotics On Human Health: A Systemic Review
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Pro-biotification of Underutilized Manila Tamarind Pulverized Seed Blended with Muskmelon
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- Authors
- Marteau, P.
- Affiliations
- Hôpital Européen Georges-Pompidou (FR)
- Corresponding author
- Marteau, Philippe
- ORCID
- Marteau, Philippe
- Venue
- Näringsforskning
- Publisher
- Informa UK Limited
- Published
- 2001-12
- Volume
- 45
- Issue
- 1
- Pages
- 22-24
- ISSN
- 0027-7878 (ISSN-L)
- OpenAlex
- W2079733493
- Cited by
- 86
- References
- 25
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 8 · 2021: 4 · 2020: 8 · 2019: 7 · 2018: 5 · 2017: 4 · 2016: 5 · 2015: 5 · 2014: 3 · 2013: 4 · 2012: 5
- FWCI
- 3.04
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Näringsforskning (publishedVersion, cc-by)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- probiotics, probiotic safety, adverse events, systemic infection, immunostimulation, gene transfer, Bifidobacterium, Lactobacillus, pharmacokinetics
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