Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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Immunity and the carotid body: implications for metabolic diseases

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Abdominal volume index trajectories and risk of diabetes mellitus: Results from the China Health and Nutrition Survey

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Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population

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Irbesartan increased PPARγ activity in vivo in white adipose tissue of atherosclerotic mice and improved adipose tissue dysfunction

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Hydrogen sulfide and the metabolic syndrome

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Obesity Hypertension: Pathophysiological Role of Leptin in Neuroendocrine Dysregulation

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Perfil metabólico-inflamatorio en la transición obesidad, síndrome metabólico y diabetes mellitus en población mediterránea. Estudio DARIOS Inflamatorio

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Association of early protein intake and pre-peritoneal fat at five years of age: Follow-up of a randomized clinical trial

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Tumor Necrosis Factor-α Gene Expression in Epicardial Adipose Tissue is Related to Coronary Atherosclerosis Assessed by Computed Tomography

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Physical training improves thermogenesis and insulin pathway, and induces remodeling in white and brown adipose tissues

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Milk fat globule membrane and its component phosphatidylcholine induce adipose browning both in vivo and in vitro

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Effect of Low Body Mass Index on the Clinical Outcomes of Japanese Patients With Acute Myocardial Infarction ― Results From the Prospective Japan Acute Myocardial Infarction Registry (JAMIR) ―

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Gestational Diabetes Mellitus Is Associated with Differences in Human Milk Hormone and Cytokine Concentrations in a Fully Breastfeeding United States Cohort

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Relationship between circulating adipokines and cholesterol efflux in subjects with severe carotid atherosclerosis

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Intrahepatic fat content correlates with soluble CD 163 in relation to weight loss induced by R oux‐en‐ Y gastric bypass

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Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes

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A macrophage-specific synthetic promoter for therapeutic application of adiponectin

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Abdominal obesity, insulin resistance, metabolic syndrome and cholesterol homeostasis

Taverne, F. J., Richard, C., Couture, P., & Lamarche, B. (2013) · PharmaNutrition · doi:10.1016/j.phanu.2013.07.003 · Cited by 23

Downregulation of CPPED1 Expression Improves Glucose Metabolism In Vitro in Adipocytes

Vaittinen, M., Kamińska, D., Käkelä, P., Eskelinen, M. J., Kolehmainen, M., Pihlajamäki, J., Uusitupa, M. I. J., & Pulkkinen, L. (2013) · Diabetes · doi:10.2337/db13-0830 · Cited by 23

Dietary Arachidonic Acid Has a Time‐Dependent Differential Impact on Adipogenesis Modulated via COX and LOX Pathways in Grass Carp Ctenopharyngodon idellus

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Innovative approach to safely induce controlled lipolysis by superparamagnetic iron oxide nanoparticles-mediated hyperthermic treatment

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Anti-obesity effects of Clausena excavata in high-fat diet-induced obese mice

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Dietary Leucine Supplement Ameliorates Hepatic Steatosis and Diabetic Nephropathy in db/db Mice

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Gentiopicroside isolated from Gentiana scabra Bge. inhibits adipogenesis in 3T3-L1 cells and reduces body weight in diet-induced obese mice

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Metformin reduces fibrosis factors in insulin resistant and hypertrophied adipocyte via integrin/ERK, collagen VI, apoptosis, and necrosis reduction

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Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity

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MicroRNA Profiling in Adipose Before and After Weight Loss Highlights the Role of miR‐223‐3p and the NLRP3 Inflammasome

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Shikonin protects against obesity through the modulation of adipogenesis, lipogenesis, and β-oxidation in vivo

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Differential Association of S100A9, an Inflammatory Marker, and p53, a Cell Cycle Marker, Expression with Epicardial Adipocyte Size in Patients with Cardiovascular Disease

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Testosterone supplementation improves glucose homeostasis despite increasing hepatic insulin resistance in male mouse model of type 2 diabetes mellitus

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Lymphocyte to High-density Lipoprotein Cholesterol Ratio is Positively Associated with Pre-diabetes, Metabolic Syndrome, and Non-traditional Cardiometabolic Risk Markers: A Cross-sectional Study at Secondary Health Care

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Cardiorenal Fat: A Cardiovascular Risk Factor With Implications in Chronic Kidney Disease

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Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo

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The Underestimated Belly Factor: Waist Circumference Is Linked to Significant Morbidity Following Isolated Coronary Artery Bypass Grafting

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Hypertriglyceridemic waist, cytokines and hyperglycaemia in Chinese

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Caveolae, lipid droplets, and adipose tissue biology: pathophysiological aspects

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Sex-Dependent Expression of Caveolin 1 in Response to Sex Steroid Hormones Is Closely Associated with Development of Obesity in Rats

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Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects

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α1-Antitrypsin Low-Density-Lipoprotein Serves as a Marker of Smoking-Specific Oxidative Stress

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Dexa Body Composition Assessment in 10-11 Year Healthy Children

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The effect of cytokines produced by human adipose tissue on monocyte adhesion to the endothelium

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The separate and combined effects of adiposity and cardiometabolic dysfunction on the risk of recurrent cardiovascular events and mortality in patients with manifest vascular disease

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Body Weight, Metabolic Dysfunction, and Risk of Type 2 Diabetes in Patients at High Risk for Cardiovascular Events or With Manifest Cardiovascular Disease: A Cohort Study

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Effects of Rosmarinus officinalis extract on human primary omental preadipocytes and adipocytes

Stefanon, B., Pomari, E., & Colitti, M. (2015) · Experimental Biology and Medicine · doi:10.1177/1535370214562341 · Cited by 21

Fish Oil Enriched in EPA, but Not in DHA, Reverses the Metabolic Syndrome and Adipocyte Dysfunction Induced by a High-Fat Diet

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Raman studies of the adipose tissue: Current state-of-art and future perspectives in diagnostics

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Obesity-related hypertension and its remission following gastric bypass surgery – A review of the mechanisms and predictive factors

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Cardiac autonomic dysfunction in obese normotensive children and adolescents

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Inverse Relationship Between Physical Activity, Adiposity, and Arterial Stiffness in Healthy Middle-Aged Subjects

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Adipose tissue quantity and composition contribute to adipokine concentrations in the subclavian vein and the inferior mesenteric vein

Faber, D. R., Moll, F. L., Vink, A., van der Waal, C., Kalkhoven, E., Schipper, H. S., Hajer, G. R., Monajemi, H., & Visseren, F. L. J. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.214 · Cited by 21

Excess Early Postnatal Weight Gain Leads to Increased Abdominal Fat in Young Children

Evelein, A. M. V., Visseren, F. L. J., van der Ent, C. K., Grobbee, D. E., & Uiterwaal, C. S. P. M. (2012) · International Journal of Pediatrics · doi:10.1155/2012/141656 · Cited by 21

Establishment and Characterization of a Newly Established Diabetic Gerbil Line

Li, X., Lü, J., Wang, Y., Huo, X., Li, Z., Zhang, S., Li, C., Guo, M., Du, X., & Chen, Z. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159420 · Cited by 21

Association between obesity phenotypes and incident hypertension among Chinese adults: a prospective cohort study

Cao, Z. K., Huang, Y., Yu, H., Yuan, S., Tang, B., Li, Q. X., Li, X. T., Yang, X., & He, Q. (2017) · Public Health · doi:10.1016/j.puhe.2017.04.018 · Cited by 21

Dietary arachidonic acid decreases the expression of transcripts related to adipocyte development and chronic inflammation in the adipose tissue of juvenile grass carp, Ctenopharyngodon idella

Tian, J., Lei, C., Ji, H., Zhou, J., Yu, H., Yang, L., Yu, E., & Xie, J. (2019) · Comparative Biochemistry and Physiology Part D Genomics and Proteomics · doi:10.1016/j.cbd.2019.02.006 · Cited by 21

The Zinc Transporter Zip7 Is Downregulated in Skeletal Muscle of Insulin-Resistant Cells and in Mice Fed a High-Fat Diet

Norouzi, S., Adulcikas, J., Henstridge, D. C., Sonda, S., Sohal, S. S., & Myers, S. (2019) · Cells · doi:10.3390/cells8070663 · Cited by 21

The combination of insulin resistance and visceral adipose tissue estimation improves the performance of metabolic syndrome as a predictor of type 2 diabetes

Antonio‐Villa, N. E., Bello‐Chavolla, O. Y., Vargas‐Vázquez, A., Mehta, R., Aguilar-Salinas, C. A., & for the Metabolic Syndrome Study Group (2020) · Diabetic Medicine · doi:10.1111/dme.14274 · Cited by 18

High Dietary Fat and Selenium Concentrations Exert Tissue- and Glutathione Peroxidase 1–Dependent Impacts on Lipid Metabolism of Young-Adult Mice

Zhao, Z., Kim, J., & Lei, X. G. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa130 · Cited by 21

Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes

Wagner, I. V., Perwitz, N., Drenckhan, M., Lehnert, H., & Klein, J. (2011) · Nutrition and Diabetes · doi:10.1038/nutd.2011.12 · Cited by 22

Postprandial Adiponectin Levels Are Associated with Improvements in Postprandial Triglycerides After Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients

Umeda, L. M., Pereira, A. Z., Carneiro, G., Arasaki, C. H., & Zanella, M. T. (2013) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2012.0042 · Cited by 21

Obstructive sleep apnoea increases lipolysis and deteriorates glucose homeostasis in patients with type 2 diabetes mellitus

Trinh, M. D., Plihalova, A., Gojda, J., Westlake, K., Spicka, J., Lattova, Z., Pretl, M., & Polak, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-83018-1 · Cited by 20

Leptin to adiponectin ratio as a useful predictor for cardiac syndrome X

Liao, Y., Liang, K., Lee, W., Lee, W.-L., Lee, I., Wang, J., Ting, C.-T., & Sheu, W. H. (2012) · Biomarkers · doi:10.3109/1354750x.2012.730550 · Cited by 20

Effect of Eight-Week High Intensity Interval Training on Omentin-1 Gene Expression and Insulin-Resistance in Diabetic Male Rats

Alizadeh, M., Asad, M. R., Faramarzi, M., & Afroundeh, R. (2017) · Annals of Applied Sport Science · doi:10.18869/acadpub.aassjournal.5.2.29 · Cited by 20

In Vitro-Generated Hypertrophic-Like Adipocytes Displaying PPARG Isoforms Unbalance Recapitulate Adipocyte Dysfunctions In Vivo

Aprile, M., Cataldi, S., Perfetto, C., Ambrosio, M. R., Italiani, P., Tatè, R., Blüher, M., Ciccodicola, A., & Costa, V. (2020) · Cells · doi:10.3390/cells9051284 · Cited by 22

Role of Adipokines and Perivascular Adipose Tissue in Abdominal Aortic Aneurysm: A Systematic Review and Meta-Analysis of Animal and Human Observational Studies

Thanigaimani, S., & Golledge, J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.618434 · Cited by 20

Managing weight and glycaemic targets in people with type 2 diabetes—How far have we come?

Blüher, M., Ceriello, A., Davies, M. J., Rodbard, H. W., Sattar, N. A., Schnell, O., Tonchevska, E., & Giorgino, F. (2022) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.330 · Cited by 19

Dietary inflammatory index and its relation to the pathophysiological aspects of obesity: a narrative review

de Mello, R. N., de Gois, B. P., Kravchychyn, A. C. P., Dâmaso, A. R., Horst, M. A., Lima, G. C., & Corgosinho, F. C. (2023) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-3997000000631 · Cited by 21

Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease

Bettinetti‐Luque, M., Trujillo‐Estrada, L., García‐Fuentes, E., Andreo‐Lopez, J., Sanchez-Varo, R. M., Garrido‐Sánchez, L., Mediavilla, A. G., López, M. G., García‐Caballero, M., Gutiérrez, A., et al. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16243 · Cited by 21

Plasma Pentraxin 3 Levels Do Not Predict Coronary Events but Reflect Metabolic Disorders in Patients with Coronary Artery Disease in the CARE Trial

Miyazaki, T., Chiuve, S. E., Sacks, F. M., Ridker, P. M., Libby, P., & Aikawa, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094073 · Cited by 20

Adiponectin: key role and potential target to reverse energy wasting in chronic heart failure

Berendoncks, A. M. V., Garnier, A., Ventura‐Clapier, R., & Conraads, V. M. (2012) · Heart Failure Reviews · doi:10.1007/s10741-012-9349-4 · Cited by 20

Metabolic and Inflammatory Profiles of Biomarkers in Obesity, Metabolic Syndrome, and Diabetes in a Mediterranean Population. DARIOS Inflammatory Study

Fernandez-Berges, D. J., Consuegra‐Sánchez, L., Peñafiel, J., de León, A. C., Vila, J., Félix-Redondo, F. J., Segura‐Fragoso, A., Lapetra, J., Guembe, M. J., Vega, T., et al. (2014) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2013.10.019 · Cited by 21

Expression of Adiponectin Receptor-1 and Prognosis of Epithelial Ovarian Cancer Patients

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Kurozu melanoidin, a novel oligoglucan-melanoidin complex from Japanese black vinegar, suppresses adipogenesis in vitro

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Adipokines, Ghrelin and Obesity‐Associated Insulin Resistance in Nondiabetic Patients with Acute Coronary Syndrome

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Isomer-specific effects of conjugated linoleic acid on blood pressure, adipocyte size and function

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Prenatal caffeine exposure induced high susceptibility to metabolic syndrome in adult female offspring rats and its underlying mechanisms

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Pathological Implication of Adipocytes in AAA Development and the Rupture

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Type 2 diabetic conditions in Otsuka Long-Evans Tokushima Fatty rats are ameliorated by 5-aminolevulinic acid

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From development to future prospects: The adipose tissue & adipose tissue organoids

Okumuş, E. B., Böke, Ö. B., Şenkal, S., & Doğan, A. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122758 · Cited by 19

Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats

Schmid, P. M., Resch, M., Schach, C., Birner, C. M., Riegger, G. A. J., Luchner, A., & Endemann, D. (2013) · Cardiovascular Diabetology · doi:10.1186/1475-2840-12-46 · Cited by 19

Association of serum angiopoietin-like protein 2 with carotid intima-media thickness in subjects with type 2 diabetes

Jung, C. H., Lee, W. J., Lee, M. J., Kang, Y. M., Jang, J. E., Leem, J., Lee, Y. L., Seol, S. M., Yoon, H. K., & Park, J. (2015) · Cardiovascular Diabetology · doi:10.1186/s12933-015-0198-z · Cited by 19

Metabolic consequences of adipose tissue dysfunction and not adiposity per se increase the risk of cardiovascular events and mortality in patients with type 2 diabetes

Franssens, B. T., Westerink, J., van der Graaf, Y., Nathoe, H. M., & Visseren, F. L. J. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.07.081 · Cited by 19

Association of plasminogen activator inhibitor-1 and low-density lipoprotein heterogeneity as a risk factor of atherosclerotic cardiovascular disease with triglyceride metabolic disorder

Iida, K., Tani, S., Atsumi, W., Yagi, T., Kawauchi, K., Matsumoto, N., & Hirayama, A. (2017) · Coronary Artery Disease · doi:10.1097/mca.0000000000000521 · Cited by 19

Adipose Tissue-Secreted Factors Alter Bladder Cancer Cell Migration

Hariharan, N., Ashcraft, K. A., Svatek, R. S., Livi, C. B., Wilson, D., Kaushik, D., Leach, R. J., & Johnson‐Pais, T. L. (2018) · Journal of Obesity · doi:10.1155/2018/9247864 · Cited by 19

Effects of Phaseolus vulgaris Extract on Lipolytic Activity and Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes: A Strategy to Prevent Obesity

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Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy

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Chemerin deficiency regulates adipogenesis is depot different through TIMP1

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Serum Cadmium Levels and Risk of Metabolic Syndrome: A Cross-Sectional Study

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FABP4 plasma levels are increased in familial combined hyperlipidemia

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High Risk of Metabolic and Adipose Tissue Dysfunctions in Adult Male Progeny, Due to Prenatal and Adulthood Malnutrition Induced by Fructose Rich Diet

Alzamendi, A., Zubiría, M. G., Moreno, G., Portales, A. E., Spinedi, E., & Giovambattista, A. (2016) · Nutrients · doi:10.3390/nu8030178 · Cited by 19

Complement‐mediated inhibition of adiponectin regulates perivascular inflammation and vascular injury in hypertension

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Key factors involved in obesity development

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High-Fat Diet Exacerbates Dermatitis through Up-Regulation of TSLP

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THE ASSOCIATION OF TYPE 2 DIABETES WITH OBESITY AND OTHER FACTORS: IN MULTINATIONAL COMMUNITY

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Sex differences in markers of metabolic syndrome and adipose tissue inflammation in obesity-prone, Osborne-Mendel and obesity-resistant, S5B/Pl rats

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Circular RNA- and microRNA-Mediated Post-Transcriptional Regulation of Preadipocyte Differentiation in Adipogenesis: From Expression Profiling to Signaling Pathway

Huang, C.-J., & Choo, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054549 · Cited by 19

Metabolic syndrome, inflammation and atherothrombosis

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SoSoSo or its active ingredient chrysophanol regulates production of inflammatory cytokines & adipokine in both macrophages & adipocytes.

Rim, H.-K., Moon, P., Choi, I.-H., Lee, E., Kim, H., & Jeong, H. (2013) · PubMed Central · Cited by 18

Thyroid Stimulating Hormone Within the Reference Range is Associated with Visceral Adiposity Index and Lipid Accumulation Product: A Population-Based Study of SPECT-China

Chen, Y., Chen, Y., Wang, N., Chen, C., Nie, X., Li, Q., Han, B., & Lu, Y. (2017) · Hormone and Metabolic Research · doi:10.1055/s-0043-122235 · Cited by 18

Loss of miR-146b-3p Inhibits Perivascular Adipocyte Browning with Cold Exposure During Aging

Pan, X., Cao, J., Cai, F., Ruan, C., Wu, F., & Gao, P. (2018) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-018-6814-x · Cited by 18

Plasminogen activator inhibitor-1, monocyte chemoattractant protein-1, e-selectin and C-reactive protein levels in response to 4-week very-high-fructose or -glucose diets

Silbernagel, G., Machann, J., Häring, H., Fritsche, A., & Peter, A. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2013.228 · Cited by 18

Visceral adiposopathy: a vascular perspective

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Relevance of Leptin and Other Adipokines in Obesity-Associated Cardiovascular Risk

Landecho, M. F., Tuero, C., Valentí, V., Bilbao, I., de la Higuera, M., & Frühbeck, G. (2019) · Nutrients · doi:10.3390/nu11112664 · Cited by 313

The role of adipokines in the development of adipose tissue dysfunction and other metabolic disorders

Mikhailov, A. A., Khalimov, Y. S., Gaiduk, S. V., Rubtsov, Y. E., & Kireeva, E. B. (2022) · Bulletin of the Russian Military Medical Academy · doi:10.17816/brmma103946 · Cited by 2

Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

Chait, A., & den Hartigh, L. J. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.00022 · Cited by 1,529

Adipose Tissue Dysfunction in Obesity

Blüher, M. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1192044 · Cited by 679