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Satellite Cells and the Muscle Stem Cell Niche

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Older Men Are as Responsive as Young Men to the Anabolic Effects of Graded Doses of Testosterone on the Skeletal Muscle

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Effects of Testosterone Supplementation on Skeletal Muscle Fiber Hypertrophy and Satellite Cells in Community-Dwelling Older Men

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Androgen Receptor in Human Skeletal Muscle and Cultured Muscle Satellite Cells: Up-Regulation by Androgen Treatment

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Frailty and sarcopenia: definitions and outcome parameters

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Drug Insight: testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging

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Skeletal muscle aging: influence of oxidative stress and physical exercise

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Testosterone and erectile function: From basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction

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Selective androgen receptor modulators as function promoting therapies

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Androgen Abuse in Athletes: Detection and Consequences

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Are androgens critical for penile erections in humans? Examining the clinical and preclinical evidence

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Selective Androgen Receptor Modulator Treatment Improves Muscle Strength and Body Composition and Prevents Bone Loss in Orchidectomized Rats

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Diabetes, Sarcopenia, and Frailty

Morley, J. E. (2008) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2008.03.004 · Cited by 186

The Physiological Role of Androgens in Penile Erection: Regulation of Corpus Cavernosum Structure and Function

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Risks and benefits of testosterone therapy in older men

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Adipocyte Accumulation in Penile Corpus Cavernosum of the Orchiectomized Rabbit: A Potential Mechanism for Veno‐occlusive Dysfunction in Androgen Deficiency

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Links Between Testosterone, Oestrogen, and the Growth Hormone/Insulin-Like Growth Factor Axis and Resistance Exercise Muscle Adaptations

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Position Stand on Androgen and Human Growth Hormone Use

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MECHANISMS IN ENDOCRINOLOGY: Estradiol as a male hormone

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Androgen regulation of satellite cell function

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Protein-Energy Wasting and Mortality in Chronic Kidney Disease

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Obesity and male hypogonadism: Tales of a vicious cycle

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Sex hormones, aging and cardiometabolic syndrome

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Binding site of activators of the cystic fibrosis transmembrane conductance regulator in the nucleotide binding domains

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Which patients with sexual dysfunction are suitable for testosterone replacement therapy?

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Phylogenetic analysis of the myostatin gene sub‐family and the differential expression of a novel member in zebrafish

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Testosterone inhibits transforming growth factor-β signaling during myogenic differentiation and proliferation of mouse satellite cells: Potential role of follistatin in mediating testosterone action

Braga, M., Bhasin, S., Jasuja, R., Pervin, S., & Singh, R. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.11.019 · Cited by 96

Testosterone and weight loss

Traish, A. M. (2014) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000086 · Cited by 95

Effects of Androgen Therapy on Adipose Tissue and Metabolism in Older Men

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Skeletal myopathy in patients with chronic heart failure: significance of anabolic‐androgenic hormones

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Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men

Gharahdaghi, N., Rudrappa, S. S., Brook, M. S., IDRIS, I. R., Crossland, H., Hamrock, C., Aziz, M. H. A., Kadi, F., Tarum, J., Greenhaff, P. L., et al. (2019) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12472 · Cited by 88

Androgens Play a Pivotal Role in Maintaining Penile Tissue Architecture and Erection: A Review

Traish, A. M. (2009) · Journal of Andrology · doi:10.2164/jandrol.108.006007 · Cited by 75

Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of β-catenin

Gentile, M. A., Nantermet, P. V., Vogel, R. L., Phillips, R., Holder, D., Hodor, P. G., Cheng, C., Dai, H. A., Freedman, L. P., & Ray, W. J. (2009) · Journal of Molecular Endocrinology · doi:10.1677/jme-09-0048 · Cited by 75

Cachexia and aging: An update based on the fourth international cachexia meeting

Morley, J. E., Anker, S. D., & Evans, W. J. (2009) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0009-x · Cited by 74

The use of phosphodiesterase 5 inhibitors with concomitant medications

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Erectile Dysfunction and Testosterone Deficiency

Blute, M., Hakimian, P., Kashanian, J. A., Shteynshluyger, A., Lee, M., & Shabsigh, R. (2008) · Frontiers of hormone research · doi:10.1159/000176048 · Cited by 71

Heavy resistance exercise training and skeletal muscle androgen receptor expression in younger and older men

Ahtiainen, J. P., Hulmi, J. J., Kraemer, W. J., Lehti, M., Nyman, K., Selänne, H., Alén, M., Pakarinen, A., Komulainen, J., Kovanen, V., et al. (2010) · Steroids · doi:10.1016/j.steroids.2010.10.012 · Cited by 70

The Top 10 Hot Topics in Aging

Morley, J. E. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.1.m24 · Cited by 70

Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis

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Testosterone and Sleep-Related Erections: An Overview*

Montorsi, F., & Oettel, M. (2005) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2005.00095.x · Cited by 61

Expression of androgen receptor target genes in skeletal muscle

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Falls and Cancer

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Anabolic-Androgenic Steroid Use in Sports, Health, and Society

Bhasin, S., Hatfield, D. L., Hoffman, J. R., Kraemer, W. J., LaBotz, M., Phillips, S. M., & Ratamess, N. A. (2021) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002670 · Cited by 63

Sex differences in body composition, metabolism‐related hormones, and energy homeostasis during aging in Wistar rats

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The cardiovascular risk of gonadotropin releasing hormone agonists in men with prostate cancer: An unresolved controversy

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Δ-4-Androstene-3,17-Dione Binds Androgen Receptor, Promotes Myogenesisin Vitro, and Increases Serum Testosterone Levels, Fat-Free Mass, and Muscle Strength in Hypogonadal Men

Jasuja, R., Ramaraj, P., Mac, R. P., Singh, A. B., Storer, T. W., Artaza, J., Miller, A., Singh, R., Taylor, W. E., Lee, M. L., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1577 · Cited by 53

Developmental Programming: Exposure to Testosterone Excess Disrupts Steroidal and Metabolic Environment in Pregnant Sheep

Salloum, B. A., Veiga‐Lopez, A., Abbott, D. H., Burant, C., & Padmanabhan, V. (2015) · Endocrinology · doi:10.1210/en.2014-2006 · Cited by 51

Androgens and Erectile Function: A Case for Early Androgen Use in Postprostatectomy Hypogonadal Men

Khera, M. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.01159.x · Cited by 48

Anabolic effects of androgens on muscles of female pelvic floor and lower urinary tract

Ho, M. H., Bhatia, N. N., & Bhasin, S. (2004) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200410000-00009 · Cited by 47

Effects of oral testosterone undecanoate therapy on bone mineral density and body composition in 322 aging men with symptomatic testosterone deficiency: a 1-year, randomized, placebo-controlled, dose-ranging study

Bouloux, P. M., Legros, J., Elbers, J. M. H., Geurts, T. B. P., Kaspers, M. J. G. H., Meehan, A. G., MEULEMAN, E. J. H., & and for the Study 43203 Investigators (2013) · The Aging Male · doi:10.3109/13685538.2013.773420 · Cited by 46

Cachexia: New Advances In The Management of Wasting Diseases

Morley, J. E., & Thomas, D. R. (2008) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2008.02.006 · Cited by 46

Benefits and Health Implications of Testosterone Therapy in Men With Testosterone Deficiency

Traish, A. M. (2017) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2017.10.001 · Cited by 46

Androgen Deficiency and Abnormal Penile Duplex Parameters in Obese Men with Erectile Dysfunction

Zohdy, W., Kamal, E., & Ibrahim, Y. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00499.x · Cited by 44

Androgen deficiency: effects on body composition

Miller, K. K. (2008) · Pituitary · doi:10.1007/s11102-008-0121-7 · Cited by 43

Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

Semirale, A. A., Zhang, X., & Wiren, K. M. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23098 · Cited by 42

Relationship of Vitamin D status with testosterone levels: a systematic review and meta-analysis

D’Andrea, S., Martorella, A., Coccia, F., Castellini, C., Minaldi, E., Totaro, M., Parisi, A., Francavilla, F., Francavilla, S., & Barbonetti, A. (2020) · Endocrine · doi:10.1007/s12020-020-02482-3 · Cited by 43

Anabolic-Androgenic Steroid Misuse: Mechanisms, Patterns of Misuse, User Typology, and Adverse Effects

Ding, J. B., Ng, M. Z., Huang, S. S., Ding, M., & Hu, K. (2021) · Journal of Sports Medicine · doi:10.1155/2021/7497346 · Cited by 41

Recovery after Heavy Resistance Exercise and Skeletal Muscle Androgen Receptor and Insulin-Like Growth Factor-I Isoform Expression in Strength Trained Men

Ahtiainen, J. P., Lehti, M., Hulmi, J. J., Kraemer, W. J., Alén, M., Nyman, K., Selänne, H., Pakarinen, A., Komulainen, J., Kovanen, V., et al. (2011) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e318202e449 · Cited by 41

Long-Term Testosterone Administration on Insulin Sensitivity in Older Men With Low or Low-Normal Testosterone Levels

Huang, G., Pencina, K. M., Li, Z., Basaria, S., Bhasin, S., Travison, T. G., Storer, T. W., Harman, S. M., & Tsitouras, P. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-02545 · Cited by 40

Cancer cachexia update in head and neck cancer: Pathophysiology and treatment

Couch, M. E., Dittus, K. L., Toth, M. J., Willis, M. S., Guttridge, D. C., George, J. R., Chang, E. Y., Gourin, C. G., & Der‐Torossian, H. (2014) · Head & Neck · doi:10.1002/hed.23696 · Cited by 41

Do androgens play any role in the physical frailty of ageing men?

O’Connell, M. D. L., Tajar, A., Roberts, S. A., & Wu, F. C. W. (2010) · International Journal of Andrology · doi:10.1111/j.1365-2605.2010.01093.x · Cited by 39

Cardiac autonomic dysfunction in anabolic steroid users

Maior, A. S., Carvalho, A. R., Neto, S. R. M., Menezes, P., Soares, P. P. D. S., & Nascimento, J. H. M. (2012) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2011.01436.x · Cited by 40

Acute Response to Endurance Exercise Stress: Focus on Catabolic/Anabolic Interplay Between Cortisol, Testosterone, and Sex Hormone Binding Globulin in Professional Athletes

Popovic, B. M., Popović, D., Μacut, D., Antić, I. B., Isailovic, T. V., Ognjanovic, S. I., Bogavac, T., Kovačević, V. E., Ilic, D. S., Petrovic, M., et al. (2018) · Journal of Medical Biochemistry · doi:10.2478/jomb-2018-0016 · Cited by 37

A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene–related peptide

Shenker, N. S., Huynh, J., Farmer, P. J., & Hutson, J. M. (2006) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2005.11.019 · Cited by 37

Estrogen-Induced Abnormal Accumulation of Fat Cells in the Rat Penis and Associated Loss of Fertility Depends upon Estrogen Exposure during Critical Period of Penile Development

Goyal, H. O., Braden, T. D., Williams, C. S., Dalvi, P. S., Mansour, M. M., & Williams, J. W. (2005) · Toxicological Sciences · doi:10.1093/toxsci/kfi233 · Cited by 37

Steroid hormones in hair reveal sexual maturity and competition in wild house mice (Mus musculus domesticus)

Carlitz, E. H. D., Runge, J., König, B., Winkler, L., Kirschbaum, C., Gao, W., & Lindholm, A. K. (2019) · Scientific Reports · doi:10.1038/s41598-019-53362-4 · Cited by 33

The effect of testosterone treatment on urodynamic findings and histopathomorphology of pelvic floor muscles in female rats with experimentally induced stress urinary incontinence

Mammadov, R., Şimşir, A., Tuğlu, İ., Evren, V., Gurer, E., & Özyurt, C. (2011) · International Urology and Nephrology · doi:10.1007/s11255-011-9938-5 · Cited by 33

Male hormones and men's quality of life

Khera, M. (2016) · Current Opinion in Urology · doi:10.1097/mou.0000000000000256 · Cited by 33

Influence of Androgens on Circulating Adiponectin in Male and Female Rodents

Yarrow, J. F., Beggs, L. A., Conover, C. F., McCoy, S. C., Beck, D. T., & Borst, S. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047315 · Cited by 33

Weapons of penile smooth muscle destruction: Androgen deficiency promotes accumulation of adipocytes in the corpus cavernosum

Traish, A. M., & Kim, N. N. (2005) · The Aging Male · doi:10.1080/13685530500328183 · Cited by 32

Emerging cardiometabolic complications of androgen deprivation therapy

Choong, K., & Basaria, S. S. (2010) · The Aging Male · doi:10.3109/13685530903410625 · Cited by 31

Sleep-Related Painful Erections: A Meta-Analysis on the Pathophysiology and Risks and Benefits of Medical Treatments

Vreugdenhil, S., Weidenaar, A. C., de Jong, I. J., & van Driel, M. F. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2017.11.006 · Cited by 31

Role of estrogen in induction of penile dysmorphogenesis: a review

Goyal, H. O., Braden, T. D., Williams, C. S., & Williams, J. W. (2007) · Reproduction · doi:10.1530/rep-07-0207 · Cited by 30

Androgen-promoted physiological traits and criminality: A test of the evolutionary neuroandrogenic theory

Ellis, L., Das, S. K., & Buker, H. (2007) · Personality and Individual Differences · doi:10.1016/j.paid.2007.10.003 · Cited by 29

Estrogen receptor-α mediates estrogen-inducible abnormalities in the developing penis

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Nandrolone and stanozolol induce leydig cell tumor proliferation through an estrogen‐dependent mechanism involving IGF‐I system

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Considerations for Sex-Cognizant Research in Exercise Biology and Medicine

O’Bryan, S. M., Connor, K. R., Drummer, D. J., Lavin, K. M., & Bamman, M. M. (2022) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2022.903992 · Cited by 26

The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications

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