Reduction in Glutathione Peroxidase 4 Increases Life Span Through Increased Sensitivity to Apoptosis

Biochemical Pathways of Caspase Activation During Apoptosis

Budihardjo, I. I., Oliver, H., Lutter, M. L., Luo, X., & Wang, X. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.269 · Cited by 2,577

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Holzenberger, M., Dupont, J., Ducos, B., Leneuve, P., Géloën, A., Even, P. C., Cervera, P., & Le Bouc, Y. (2003) · Nature · doi:10.1038/nature01298 · Cited by 2,109

Tumor spectrum analysis in p53-mutant mice

Jacks, T., Remington, L., Williams, B. O., Schmitt, E. M., Halachmi, S., Bronson, R. T., & Weinberg, R. A. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00002-6 · Cited by 2,051

Suppression of Aging in Mice by the Hormone Klotho

Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science · doi:10.1126/science.1112766 · Cited by 1,935

Extension of murine life span by overexpression of catalase targeted to mitochondria

Schriner, S. E., Linford, N. J., Martin, G. M., Treuting, P., Ogburn, C. E., Emond, M., Coskun, P. E., Ladiges, W., Wolf, N., Van Remmen, H., et al. (2005) · Science · doi:10.1126/science.1106653 · Cited by 1,724

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Migliaccio, E., Giorgio, M., Mele, S., Pelicci, G., Reboldi, P., Pandolfi, P. P., Lanfrancone, L., & Pelicci, P. G. (1999) · Nature · doi:10.1038/46311 · Cited by 1,712

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Kagan, V. E., Tyurin, V. A., Jiang, J., Tyurina, Y. Y., Ritov, V. B., Amoscato, A. A., Osipov, A. N., Belikova, N. A., Kapralov, A. A., Kini, V., et al. (2005) · Nature Chemical Biology · doi:10.1038/nchembio727 · Cited by 1,256

Lipid hydroperoxide generation, turnover, and effector action in biological systems

Girotti, A. W. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32182-9 · Cited by 1,215

Mechanisms of free radical oxidation of unsaturated lipids

Porter, N. A., Caldwell, S. E., & Mills, K. A. (1995) · Lipids · doi:10.1007/bf02536034 · Cited by 1,208

Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis

Giorgio, M., Migliaccio, E., Orsini, F., Paolucci, D., Moroni, M., Contursi, C., Pelliccia, G., Luzi, L., Minucci, S., Marcaccio, M., et al. (2005) · Cell · doi:10.1016/j.cell.2005.05.011 · Cited by 1,176

Association of Genetic Polymorphisms for Glutathione Peroxidase Genes with Obesity in Spanish Children

Rupérez, A. I., Olza, J., Gil‐Campos, M., Leis, R., Mesa, M. D., Tojo, R., Cañete, R., Gil, Á., & Aguilera, C. M. (2014) · Lifestyle Genomics · doi:10.1159/000368833 · Cited by 32

Dietary Fish Oil Promotes Colonic Apoptosis and Mitochondrial Proton Leak in Oxidatively Stressed Mice

Fan, Y.-Y., Ran, Q., Toyokuni, S., Okazaki, Y., Callaway, E. S., Lupton, J. R., & Chapkin, R. S. (2011) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-10-0368 · Cited by 32

Elevated Mitochondrial Oxidative Stress Impairs Metabolic Adaptations to Exercise in Skeletal Muscle

Crane, J. D., Abadi, A., Hettinga, B. P., Ogborn, D. I., MacNeil, L., Steinberg, G. R., & Tarnopolsky, M. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081879 · Cited by 32

Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis

Uzhachenko, R. V., Boyd, K. L., Olivares–Villagómez, D., Zhu, Y., Goodwin, J. S., Rana, T., Shanker, A., Tan, W. J. T., Bondar, T., Medzhitov, R. M., et al. (2017) · Aging · doi:10.18632/aging.101213 · Cited by 29

Inhibition of Adenylyl Cyclase Type 5 Increases Longevity and Healthful Aging through Oxidative Stress Protection

Vatner, S. F., Pachon, R. E., & Vatner, D. E. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/250310 · Cited by 30

Oxidative stress induced by 2,4‐phenoxyacetic acid in liver of female rats and their progeny: Biochemical and histopathological studies

Troudi, A., Amara, I. B., Mahjoubi-Samet, A., & Zeghal, N. (2010) · Environmental Toxicology · doi:10.1002/tox.20624 · Cited by 30

Cyclophosphamide-induced GPX4 degradation triggers parthanatos by activating AIFM1

Liu, L., Liu, B., Guan, G., Kang, R., Dai, Y., & Tang, D. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.03.098 · Cited by 29

Mitochondria, Cellular Stress Resistance, Somatic Cell Depletion and Lifespan

Robb, E. L., Page, M. M., & Stuart, J. A. (2009) · Current Aging Science · doi:10.2174/1874609810902010012 · Cited by 27

Change in several Antioxidant Enzymes Activity and Seed Yield by Water Deficit Stress in Soybean (Glycine max L.) Cultivars

MASOUMI, H., MASOUMI, M., Darvish, F., Daneshian, J., Nourmohammadi, G., & HABIBI, D. (2010) · Notulae Botanicae Horti Agrobotanici Cluj-Napoca · doi:10.15835/nbha3834936 · Cited by 26

Genes regulated by caloric restriction have unique roles within transcriptional networks

Swindell, W. R. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.06.001 · Cited by 26

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

Yen, K., & Mobbs, C. V. (2009) · AGE · doi:10.1007/s11357-009-9110-7 · Cited by 25

Antioxidant and pancreas‐protective effect of red mold fermented products on streptozotocin‐induced diabetic rats

Shi, Y., & Pan, T. (2010) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4115 · Cited by 24

Nuclear selenoproteins and genome maintenance

Zhang, X., Zhang, L., Zhu, J., & Cheng, W. (2015) · IUBMB Life · doi:10.1002/iub.1455 · Cited by 24

Protective Effects of Molsidomine Against Cisplatin-Induced Nephrotoxicity

Karakoc, H. T. E., Altıntaş, R., Parlakpınar, H., Polat, A., Şamdancı, E., Sağır, M., & Duran, Z. R. (2015) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/58970 · Cited by 24

Clinical and Genetic Aspects of Epilepsy

Heron, S., & Mulley, J. (2011) · InTech eBooks · doi:10.5772/1138 · Cited by 24

Intramammary infusion of lipopolysaccharide promotes inflammation and alters endometrial gene expression in lactating Holstein cows

Campos, C. C., Hartling, I., Kaur, M., Fernandes, A. C. D. C., dos Santos, R. M., & Cerri, R. L. A. (2018) · Journal of Dairy Science · doi:10.3168/jds.2018-14393 · Cited by 23

Role/s of ‘Antioxidant’ Enzymes in Ageing

Veal, E. A., Jackson, T., & Latimer, H. R. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2835-0_14 · Cited by 25

New perspectives on ferroptosis and its role in hepatocellular carcinoma

Cong, T., Luo, Y., Fu, Y. H. H., Liu, Y., Li, Y., & Li, X. (2022) · Chinese Medical Journal · doi:10.1097/cm9.0000000000002327 · Cited by 21

Lifespan extension in Caenorhabiditis elegans by several traditional Chinese medicine formulas

Wan, F., Zhi, D., Liu, D., Xian, J., Li, M., AbuLizi, A., Ju, W., & Li, H. (2014) · Biogerontology · doi:10.1007/s10522-014-9508-1 · Cited by 20

Mitochondrial J haplogroup is associated with lower blood pressure and anti-oxidant status: findings in octo/nonagenarians from the BELFAST Study

Rea, I. M., McNerlan, S., Archbold, G. P. R., Middleton, D., Curran, M. D., Young, I. S., & Ross, O. A. (2012) · AGE · doi:10.1007/s11357-012-9444-4 · Cited by 19

VOLATILE CONSTITUENTS AND ANTIOXIDANT PROPERTY OF ESSENTIAL OIL FROM PLECTRANTHUS AMBOINICUS (LOUR)

Grace, V. M. B. (2012) · International Journal of Pharma and Bio Sciences · Cited by 19

Targeting cell death mechanisms: the potential of autophagy and ferroptosis in hepatocellular carcinoma therapy

Liu, B., Liu, L., & Liu, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1450487 · Cited by 19

The Role of Non-Coding RNAs in the Neuroprotective Effects of Glutathione

Kinoshita, C., & Aoyama, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084245 · Cited by 19

OTULIN confers cisplatin resistance in osteosarcoma by mediating GPX4 protein homeostasis to evade the mitochondrial apoptotic pathway

Zheng, Z., Zeng, Y., Bao, X., Huang, C., Guo, F., Xu, F., & Luo, Z. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03249-8 · Cited by 18

An Objective Appraisal of the Free Radical Theory of Aging

Lustgarten, M. S., Müller, F. L., & Remmen, H. V. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-378638-8.00008-7 · Cited by 18

Haemato-biochemical, mutagenic, and histopathological changes in Oreochromis niloticus exposed to BTX

Sayed, A. E. H., Idriss, S. K. A., Abd‐Elghaffar, S. K., & Hussein, A. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-26604-2 · Cited by 16

Long-Term Dietary Supplementation with a Yang-Invigorating Chinese Herbal Formula Increases Lifespan and Mitigates Age-Associated Declines in Mitochondrial Antioxidant Status and Functional Ability of Various Tissues in Male and Female C57BL/6J Mice

Ko, K. M., Chiu, P. Y., Leung, H. Y., Siu, A. H. L., Chen, N., Leong, E. P. K., & Poon, M. K. T. (2010) · Rejuvenation Research · doi:10.1089/rej.2009.0893 · Cited by 16

A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging

de Magalhães, J. P., Thompson, L. M., de Lima, I., Gaskill, D., Li, X., Thornton, D., Yang, C., & Palmer, D. H. (2018) · Genetics · doi:10.1534/genetics.118.300821 · Cited by 17

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability

D’Ambrosio, M., White, M. E. H., Gavriil, E.-S., Bousset, L., Birch, J., Gruevska, A., Pasquini, E., Colucci, M., Fong, W., Mosole, S., et al. (2026) · Nature Cell Biology · doi:10.1038/s41556-026-01921-z · Cited by 17

Effects of Selenium on Tebuconazole-Induced Hepatotoxicity in Adult Rats

Saad, H. B., Kammoun, I., Boudawara, T. S., Km, Z., Hakim, A., & Amara, I. (2017) · Research and reviews in biosciences · Cited by 14

Effects of Etlingera elatior extracts on lead acetate-induced testicular damage: A morphological and biochemical study

HAW, K. Y., Chakravarthi, S., Haleagrahara, N., & Rao, M. (2011) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2011.355 · Cited by 14

Biochemical Studies on the Amelioration of Petroleum Product Intoxication with Indigenous Plants

Ujowundu, C. O. (2012) · International Journal of Biochemistry Research & Review · doi:10.9734/ijbcrr/2012/1023 · Cited by 14

Antioxidant response of ridgetail white prawn Exopalaemon carinicauda to harmful dinoflagellate Prorocentrum minimum exposure and its histological change

Mu, C., Ren, X., Ge, Q., Wang, J., & Li, J. (2017) · Journal of Ocean University of China · doi:10.1007/s11802-017-3170-6 · Cited by 14

The Role of Ferric Nitrilotriacetate in Renal Carcinogenesis and Cell Death: From Animal Models to Clinical Implications

Okazaki, Y. (2022) · Cancers · doi:10.3390/cancers14061495 · Cited by 13

Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma

Azumi, M., Kusama, K., Yoshie, M., Nakano, S., Tsuru, A., Kato, T., & Tamura, K. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176544 · Cited by 13

Astaxanthin Added during Post-Warm Recovery Mitigated Oxidative Stress in Bovine Vitrified Oocytes and Improved Quality of Resulting Blastocysts

Dujíčková, L., Olexíková, L., Makarevich, A. V., Bartkova, A. R., Němcová, L., Chrenek, P., & Strejček, F. (2024) · Antioxidants · doi:10.3390/antiox13050556 · Cited by 14

Glutathione Peroxidase-4

Maiorino, M., Bosello-Travain, V., Cozza, G., Roveri, A., Toppo, S., & Ursini, F. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1025-6_14 · Cited by 13

Role of Antioxidant in Testicular Integrity

Dare, B. (2014) · Annual Research & Review in Biology · doi:10.9734/arrb/2014/4453 · Cited by 17

BTEX induces histopathological alterations, oxidative stress response and DNA damage in the testis of the freshwater leech Erpobdella johanssoni (Johansson, 1927)

Khaled, I., Saidi, I., Ferjani, H., Ahmed, R. B., Alrezaki, A., Guesmi, F., Bouzenna, H., & Harrath, A. H. (2022) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2022.102196 · Cited by 11

Glutathione Peroxidase 4

Maiorino, M., Bosello-Travain, V., Cozza, G., Miotto, G., Orian, L., Roveri, A., Toppo, S., Zaccarin, M., & Ursini, F. (2016) · Springer eBooks · doi:10.1007/978-3-319-41283-2_18 · Cited by 11

Advances in vertebrate aging research 2007

Austad, S. N. (2008) · Aging Cell · doi:10.1111/j.1474-9726.2008.00374.x · Cited by 10

Exposure to Prorocentrum minimum Induces Oxidative Stress and Apoptosis in the Ridgetail White Prawn, Exopalaemon carinicauda

Mu, C., Ge, Q., & Li, J. (2019) · Journal of Ocean University of China · doi:10.1007/s11802-019-3846-1 · Cited by 9

Thioredoxin and aging: What have we learned from the survival studies?

Roman, M. G., Flores, L. C., Cunningham, G. M., Cheng, C., Allen, C., Hubbard, G. B., Bai, Y., Saunders, T. L., & Ikeno, Y. (2020) · Aging Pathobiology and Therapeutics · doi:10.31491/apt.2020.09.028 · Cited by 8

Neurotropic peptide HLDF-6-amide reduces age-related decline in sexual activity in old male rats

Sokolov, O. Y., Prokhorova, T. A., Терешкина, Е. Б., Zozulya, S. A., Simonov, A. N., Кост, Н. В., Dadayan, A. K., Bogachouk, A. P., & Zolotarev, Y. A. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111329 · Cited by 7

AMELIORATIVE IMPACTS OF GRAPE SEED EXTRACT ON GROWTH PERFORMANCE, IMMUNE RESPONSE, ANTIOXIDANT CAPACITY AND BIOCHEMICAL CONSTITUENTS IN BROILERS EXPOSED TO FUMONISIN B1

Hassan, R., Eid, Y. Z., El-Hassan, E. A., Farouk, Z., Gorgy, M., El-Gbaly, M., & Basuney, H. (2023) · Egyptian Journal of Nutrition and Feeds · doi:10.21608/ejnf.2023.316701 · Cited by 6

Naturally Occurring Antioxidants

Ronzio, R. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-43044-9.00097-2 · Cited by 6

The analyse of the antioxidant effect of natural peloidotherapy in aging process

Stanciu, L.-E., Iliescu, M. G., Petcu, L. C., Uzun, A.-B., Ungureanu, A. E., Ungur, R.-A., Ciortea, V. M., Irsay, L., Ionescu, E. V., Oprea, C., et al. (2023) · Balneo and PRM Research Journal · doi:10.12680/balneo.2023.541 · Cited by 5

The effects of erythropoietin and dextran and saline on brain edema and lipid peroxidation in experimental head trauma.

Başarslan, S. K. (2015) · Turkish Journal of Trauma and Emergency Surgery · doi:10.5505/tjtes.2015.66502 · Cited by 5

Induction of cancer cell-specific ferroptosis by non-thermal plasma exposure

Okazaki, Y., & Toyokuni, S. (2020) · Japanese Journal of Applied Physics · doi:10.35848/1347-4065/abbc56 · Cited by 5

Extension of Life Span in Laboratory Mice

Unnikrishnan, A., Deepa, S. S., Herd, H. R., & Richardson, A. G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811353-0.00019-1 · Cited by 7

Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases

Nguyen, H. V. M., Ran, Q., Salmon, A. B., Ahn, B., Chiao, Y. A., Bhaskaran, S., & Richardson, A. G. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.10.269 · Cited by 4

Gpx4 and Ferroptosis

Ran, Q., & Mozolewska, P. (2019) · Springer eBooks · doi:10.1007/978-3-030-26780-3_6 · Cited by 4

Renoprotective Effect of Centaurea choulettiana Pomel (Asteraceae) Leaves on Cisplatin-induced Oxidative Stress and Renal dysfunction in Mice

Bioud, K., Azzouzi, D., Benrebai, M., Mekkiou, R., Samir, B., Benayache, F., & Ameddah, S. (2017) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2017.71122 · Cited by 4

The Biology of Aging: Implications for Diseases of Aging and Health Care in the Twenty‐First Century

Watt, D. F. (2014) · Wiley eBooks · doi:10.1002/9781118730676.ch1 · Cited by 4

Ferroptosis-related stress during aging and its relevance to disease

Maher, P. A., Soriano‐Castell, D., Dar, N. J., Soriano, S., & Currais, A. J. M. (2025) · GeroScience · doi:10.1007/s11357-025-01929-7 · Cited by 6

Role of Oxidative Stress in Aging

Knoefler, D., Tienson, H. L., & Jakob, U. (2013) · Springer eBooks · doi:10.1007/978-94-007-5787-5_14 · Cited by 3

Comparative analysis of expressed sequence tags (ESTs) between normal group and softness syndrome group in Halocynthia roretzi

Jeong, J. E., Kang, S. W., Shin, Y. K., Jun, J. C., Kim, Y., Hur, Y. B., Kim, J., Chae, S., Lee, J., Choi, I. H., et al. (2011) · Molecular & Cellular Toxicology · doi:10.1007/s13273-011-0045-6 · Cited by 3

Theories and Mechanisms of Aging

Behl, C., & Ziegler, C. (2013) · SpringerBriefs in molecular medicine · doi:10.1007/978-3-642-45179-9_3 · Cited by 3

Effects of different levels of water deficit stresses on the morphologic properties of root, antioxidants activity and the seed yield in five cultivars of soybean (Glycine max L).

Masoumi, H., Azizi, J., Masoumi, M., & Rahimi, M. (2014) · International journal of agriculture innovation and research · Cited by 3

Naturally Occurring Antioxidants

Ronzio, R. A. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-2333-5.00108-5 · Cited by 3

Mouse Models for Glutathione Peroxidase 4 (GPx4)

Conrad, M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1025-6_43 · Cited by 3

Assessment of Antioxidant activity of Silver Nanoparticles synthesized using aqueous extract of Schizophyllum commune inTriazophos-induced oxidative stress in albino ratsPreprint

Kumar, A. N., & Haque, A. (2023) · Research Square · doi:10.21203/rs.3.rs-2868664/v1 · Cited by 3

EVALUATION OF IN VIVO WOUND HEALING ACTIVITY OF THE EXTRACT AND OLEUROPEIN FROM MORINDA TINCTORIA ROXB. (RUBIACEAE)- A TRADITIONAL MEDICINAL PLANT.

Ibrahim, A., Nagarajan, A., & Majeed, M. A. (2017) · International Journal of Advanced Research · doi:10.21474/ijar01/5403 · Cited by 2

The Use of Gpx4 Knockout Mice and Transgenic Mice to Study the Roles of Lipid Peroxidation in Diseases and Aging

Ran, Q., & Liang, H. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-956-7_12 · Cited by 2

Modulation of antioxidant status, carbohydrate and lipid metabolism by melatonin on streptozotocin induced diabetic rats

Mirunalini, S., Jayakumar, P., & Gomathy, T. (2013) · Journal Of Biochemical Technology · Cited by 2

Tissue-specific changes in antioxidant defence during ageing: the effect of chronic cold exposure

Djuric, S., Zakić, T., Korać, A., Korać, B., & Janković, A. (2026) · Journal of Comparative Physiology B · doi:10.1007/s00360-025-01646-9 · Cited by 1

Oxidative Stress in Dry Eye Disease: Molecular Mechanisms and Emerging Therapeutic Strategies

Tang, T., Yang, J., & Yin, H. (2026) · Biomolecules · doi:10.3390/biom16050718 · Cited by 1

Hepatoprotective effects of capping protein gelsolin against hyperoxia-induced hepatotoxicity, oxidative stress and DNA damage in neonatal rats

Per, S., Köse, M., Özdemi̇r, A., & Pandır, D. (2018) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2018.01.007 · Cited by 1

Protective Effects of Micro-Emulsion of Sour Cherry (Prunus cerasus L.) Kernel Extract on Methimazole-Induced Nephrotoxicity in Mice

Kalantari‬, H., Salimi, A., Molavinia, S., Kheradmand, P., Goudarzi, M., Fehér, P. S., Ujhelyi, Z., Kalantari, A., & Vecsernyés, M. (2019) · Jundishapur Journal of Natural Pharmaceutical Products · doi:10.5812/jjnpp.58994 · Cited by 1

Manipulating mitochondrial reactive oxygen species alters survival in unexpected ways in a Drosophila Cdk5 model of neurodegeneration

Wodrich, A. P. K., Harris, B. T., & Giniger, E. (2024) · Biology Open · doi:10.1242/bio.060515 · Cited by 2

Free Radicals in Aging – An Evolutionary Perspective

Csiszár, A., & Ungvari, Z. I. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_14 · Cited by 1

Desempenho reprodutivo de vacas leiteiras lactantes acometidas pela mastite clínica de ocorrência espontânea ou induzida por LPS de Escherichia coli

Campos, C. C. (2017) · doi:10.14393/ufu.te.2018.12 · Cited by 1

Fatty acid desaturation controls cellular fate decisions between senescence and ferroptosis

Kuehnemann, C., Jezak, S. T., Mogck, B. A., Kura, N., Tariq, R., Che, Y., Vaittinen, M., Siokas, I., Deshpande, S., Guthrie, C., et al. (2026) · Cell · doi:10.1101/2024.10.03.616257 · Cited by 1

A study of glutathione peroxidase 4 function in human intestinal epithelial cells

Ezea, P. C. (2013) · Cited by 1

Untersuchungen zur Rolle der Glutathion-Peroxidase 4 als möglicher Redox-Sensor in Säugetierzellen

Grünler, N. (2015) · Site cant be reached · doi:10.5282/edoc.18272

Epilepsy: Selenium and Aging

Rocourt, C. R. B., Yu, Y. L., & Cheng, W. (2011) · InTech eBooks · doi:10.5772/17203

Antioxidative Treatment for Neuroprotection in Glaucoma

Yuki, K. (2014) · Springer eBooks · doi:10.1007/978-4-431-54965-9_4

Behavioral changes and mechanisms – an experimental study on aging in rodents

Fahlström, A. (2011) · Figshare

Synergestic Effect of Milk Thistle and Grape Seed Extracts on the Recovery of Fumonisin b1 Toxicity in Rats.

El-Shafeey, M. E. A., El-Adawi, H., Al-Azhari, D., ., A. E.-W. A., & AbdelMohsen, M. M. (2012) · Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology/Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology · doi:10.21608/eajbsc.2012.16126

Hepatoprotective and Antidiabetic Effect of Phyllanthus Extract

Lim, C. Y. (2011)

Intracellular antioxidant and DNA repair enzymes as correlates of stress resistance and longevity in vertebrates

Page, M. M. (2011) · Brock University Digital Repository (Brock University)

Effect of chitosan on the induction of DNA damage response by selenium compounds

Zhang, S., Zeng, H., Luo, Y., Wang, Q., & Cheng, W. (2010) · The FASEB Journal · doi:10.1096/fasebj.24.1_supplement.lb251

Selenoproteins in Skeletal Development and Disease: Lessons from Trsp Deletion in Murine Bone and Cartilage Progenitor Cells

Downey, C. M., & Jirik, F. R. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1025-6_45

Theorien und Mechanismen des Alterns

Behl, C., & Ziegler, C. (2015) · Springer eBooks · doi:10.1007/978-3-662-48250-6_3

EXPLORING THE ROLE OF ELEVATED LIPID PEROXIDATION AND GLUTATHIONE PEROXIDASE 4 IN METABOLIC SYNDROME AND CARDIAC REMODELING IN OBESITY

Katunga, L. A. (2016) · The Scholarship East Carolina University's Institutional Repository (East Carolina University)

EVALUATION OF THE ROLE OF ANTIOXIDANT IN AGE-RELATED CATARACT PATIENTS

Ramadan, M., & Ibraheem, L. (2014) · Zagazig University Medical Journal · doi:10.21608/zumj.2014.4422

Genetic features of the glutathyon system of long livers of Carpathian region with comorbid pathology: arterial hypertension and osteoarthrosis

Kozovyi, R., Kovalchuk, L. Y., & Еrstenyuk, H. M. (2018) · Faktori eksperimental noi evolucii organizmiv · doi:10.7124/feeo.v23.1014

Prognostic Significance of Glutathione Peroxidase (GSH-Px) Levels in Lumbar Degenerative Disc Disease

Yaltırık, C. K., Yılmaz, S. G., Akdeniz, F. T., Sümerkent, K., Özdoğan, S., & İşbir, T. (2020) · Experimed · doi:10.26650/experimed.2020.0011

Mitochondrial dysfunction in the diabetic heart: Cardioprotection from a novel mitochondrially-targeted therapeutic

Dabkowski, E. R. (2010) · doi:10.33915/etd.3251

MANIPULATING MITOCHONDRIAL REACTIVE OXYGEN SPECIES ALTERS SURVIVAL IN UNEXPECTED WAYS IN A DROSOPHILA MODEL OF NEURODEGENERATIONPreprint

Wodrich, A. P. K., Harris, B. T., & Giniger, E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.25.586603

A study of neurodegeneration and neuroprotection in Nothobranchius guentheri

Genade, T. (2012) · Open University of Cape Town (University of Cape Town)

Peptide HLDF-6 Exhibits Neuroprotective Activity in Neurodegenerative Diseases

Zolotarev, Y. A., & Dadayan, A. K. (2025) · Neurochemical Journal · doi:10.1134/s1819712425700618

PPARγ mediated ferroptosis in metabolic bone diseases

Shuai, Q., Guan, Z., Yang, W., Tian, J., & Huang, S. (2026) · Pathology - Research and Practice · doi:10.1016/j.prp.2026.156662

Selenium in aging and longevity

Pierce, W. G., & Mackrill, J. J. (2026) · Biochimie · doi:10.1016/j.biochi.2026.09.002 · Cited by 1

Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis (Journals of Gerontology - Series A Biological Sciences and Medical Sciences (2007) 62, 9, (932-942))

Remmen, H. V. (2008) · Journals of Gerontology Series A-biological Sciences and Medical Sciences

Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis*

Ran, Q.-T., Liang, H.-Y., Gu, M., Qi, W., Walter, C., Roberts, L., Herman, B., Richardson, A., & Remmen, H. V. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410387200 · Cited by 242

The Use of Gpx4 Knockout Mice and Transgenic Mice to Study the Roles of Lipid Peroxidation in Diseases and Aging

Ran, Q., & Liang, H. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-956-7_12 · Cited by 2

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Yant, L. J., Ran, Q., Rao, L., Van Remmen, H., Shibatani, T., Belter, J. G., Motta, L., Richardson, A., & Prolla, T. A. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01360-6 · Cited by 797

The role of the selenoprotein GPx2 during colorectal carcinogenesis

Kipp, A. P., Mueller, M.-F., Florian, S., Krehl, S., Löwinger, M., & Brigelius‐Flohé, R. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.08.245 · Cited by 1