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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

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Glutathione peroxidases and redox-regulated transcription factors

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Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

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An essential role for functional lysosomes in ferroptosis of cancer cells

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Ferroptosis in health and disease

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Selenium and brain function: a poorly recognized liaison

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Mitochondrial Thiols in Antioxidant Protection and Redox Signaling: Distinct Roles for Glutathionylation and Other Thiol Modifications

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Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation–Mediated Cell Death in Mice

Qi, J., Kim, J.-W., Zhou, Z., Lim, C.-W., & Kim, B. (2020) · The American Journal of Pathology · doi:10.1016/j.ajpath.2019.09.011 · Cited by 338 · see citing works

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney

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Mitochondrial glutathione peroxidase 4 disruption causes male infertility

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The essential elements of Alzheimer’s disease

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Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

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Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

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Emerging mechanisms and targeted therapy of ferroptosis in cancer

Wang, H., Cheng, Y., Mao, C., Liu, S., Xiao, D., Huang, J. X., & Tao, Y. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.03.022 · Cited by 321 · see citing works

Superoxide Radicals in the Execution of Cell Death

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SR/ER–mitochondrial local communication: Calcium and ROS

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Glutathione peroxidases in different stages of carcinogenesis

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Interplay between oxidant species and energy metabolism

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Ferroptosis: principles and significance in health and disease

Chen, F., Kang, R., Tang, D., & Liu, J. (2024) · Journal of Hematology & Oncology · doi:10.1186/s13045-024-01564-3 · Cited by 314 · see citing works

A guideline on the molecular ecosystem regulating ferroptosis

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Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease

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Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system

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Oxidative stress and diabetes: What can we learn about insulin resistance from antioxidant mutant mouse models?

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Molecular Mechanisms in Spermatogenesis

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The Nuclear Form of Phospholipid Hydroperoxide Glutathione Peroxidase Is a Protein Thiol Peroxidase Contributing to Sperm Chromatin Stability

Conrad, M., Moreno, S. G., Sinowatz, F., Ursini, F., Kölle, S., Roveri, A., Brielmeier, M., Wurst, W., Maiorino, M., & Bornkamm, G. W. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.17.7637-7644.2005 · Cited by 270 · see citing works

The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities

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The role of the selenoprotein GPx2 during colorectal carcinogenesis

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Mouse Models for Glutathione Peroxidase 4 (GPx4)

Conrad, M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1025-6_43 · Cited by 3 · see citing works

Embryonic fibroblasts from Gpx4+/− mice: a novel model for studying the role of membrane peroxidation in biological processes

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Expression of Inactive Glutathione Peroxidase 4 Leads to Embryonic Lethality, and Inactivation of the Alox15 Gene Does Not Rescue Such Knock-In Mice

Brütsch, S. H., Wang, C. C., Li, L., Stender, H., Neziroglu, N., Richter, C., Kühn, H., & Borchert, A. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5967 · Cited by 108 · see citing works

Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals

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