The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Insulin dependant diabetes mellitus: implications for male reproductive function
Open accessAbstract
BACKGROUND: Diabetes mellitus (DM) is increasing in men of reproductive age. Despite this, the prevalence of diabetes in men attending fertility clinics is largely unknown. Furthermore, studies examining the effects of DM on sperm fertility potential have been limited to conventional semen analysis. METHODS: Conventional semen analysis (semen volume, sperm count, motility and morphology) was performed for 27 diabetic (mean age 34+/-2 years) and 29 non-diabetic subjects (control group, men undergoing routine infertility investigations, mean age 33+/-1 years). Nuclear DNA (nDNA) fragmentation was assessed using the alkaline Comet assay and mitochondrial DNA (mtDNA) deletions by Long-PCR. RESULTS: Other than a small, but significant, reduction in semen volume in diabetic men (2.6 versus 3.3 ml; P<0.05), conventional semen parameters did not differ significantly from control subjects. Diabetic subjects had significantly higher mean nDNA fragmentation (53 versus 32%; P<0.0001) and median number of mtDNA deletions (4 versus 3; P<0.05) compared with control subjects. CONCLUSIONS: Diabetes is associated with increased sperm nuclear and mtDNA damage that may impair the reproductive capability of these men.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study
Feldman, H. A., Goldstein, I., Hatzichristou, D. G., Krane, R. J., & McKinlay, J. B. (1994) · Journal of Urology · doi:10.1016/s0022-5347(17)34871-1 · Cited by 5,074
Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men
Guzick, D. S., Overstreet, J. W., Factor-Litvak, P., Brazil, C. K., Nakajima, S. T., Coutifaris, C., Carson, S. A., Cisneros, P., Steinkampf, M. P., Hill, J. A., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa003005 · Cited by 1,336
Predictive value of abnormal sperm morphology in in vitro fertilization
Kruger, T. F., Acosta, A. A., Simmons, K. F., Swanson, R. J., Matta, J. F., & Oehninger, S. (1988) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59660-5 · Cited by 1,159
Variation and trends in incidence of childhood diabetes in Europe
(2000) · The Lancet · doi:10.1016/s0140-6736(99)07125-1 · Cited by 755
SEARCH for Diabetes in Youth Study Group (2006) · Pediatrics · doi:10.1542/peds.2006-0690 · Cited by 726
Paternal Cigarette Smoking and the Risk of Childhood Cancer Among Offspring of Nonsmoking Mothers
Ji, B.-T., Shu, X.-O., Zheng, W., Ying, D.-M., Linet, M. S., Wacholder, S., Gao, Y.-T., & Jin, F. (1997) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/89.3.238 · Cited by 423
Trisini, A. T., Singh, N. P., Duty, S. M., & Hauser, R. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.05.087 · Cited by 83
Cited by
Oxidative stress and male infertility—a clinical perspective
Tremellen, K. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn004 · Cited by 1,507
Origins of lifetime health around the time of conception: causes and consequences
Fleming, T. P., Watkins, A. J., Velazquez, M. A., Mathers, J. C., Prentice, A. M., Stephenson, J., Barker, M., Saffery, R., Yajnik, C. S., Eckert, J. J., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30312-x · Cited by 1,147
Antioxidant Systems and Oxidative Stress in the Testes
Aitken, R. J., & Roman, S. D. (2008) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.1.1.6843 · Cited by 834
Asadi, N. (2017) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2017/23927.9886 · Cited by 431
The effect of obesity on sperm disorders and male infertility
Du Plessis, S. S., Cabler, S., McAlister, D. A., Sabanegh, E., & Agarwal, A. (2010) · Nature Reviews Urology · doi:10.1038/nrurol.2010.6 · Cited by 422
Metadata
- Authors
- Agbaje, I. M., Rogers, D. A., McVicar, C. M., McClure, N., Atkinson, A. B., Mallidis, C., & Lewis, S. E. M.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-07-01
- Volume
- 22
- Issue
- 7
- Pages
- 1871-1877
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2106575294
- Cited by
- 482
- References
- 7
- FWCI
- 17.52
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Insulin dependant diabetes mellitus: implications for male reproductive function. https://app.cochat.ai/papers/10.1093/humrep/dem077
- The paper
- Agbaje, I. M., Rogers, D. A., McVicar, C. M., McClure, N., Atkinson, A. B., Mallidis, C., & Lewis, S. E. M. (2007). Insulin dependant diabetes mellitus: implications for male reproductive function. Human Reproduction. https://doi.org/10.1093/humrep/dem077
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.