Origins of lifetime health around the time of conception: causes and consequences

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

Chen, Q., Yan, M., Cao, Z., Li, X., Zhang, Y., Shi, J., Feng, G.-H., Peng, H., Zhang, X., Zhang, Y., et al. (2016) · Science · doi:10.1126/science.aad7977 · Cited by 1,470 · see citing works

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327 · see citing works

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

Sharma, U., Conine, C. C., Shea, J. M., Boskovic, A., Derr, A. G., Bing, X. Y., Belleannee, C., Kucukural, A., Serra, R. W., Sun, F., et al. (2016) · Science · doi:10.1126/science.aad6780 · Cited by 1,275 · see citing works

Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?

Hanson, M. A., & Gluckman, P. D. (2014) · Physiological Reviews · doi:10.1152/physrev.00029.2013 · Cited by 1,188 · see citing works

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

Carone, B. R., Fauquier, L., Habib, N., Shea, J. M., Hart, C. E., Li, R., Bock, C., Li, C., Gu, H., Zamore, P. D., et al. (2010) · Cell · doi:10.1016/j.cell.2010.12.008 · Cited by 1,157 · see citing works

Dietary Protein Restriction of Pregnant Rats Induces and Folic Acid Supplementation Prevents Epigenetic Modification of Hepatic Gene Expression in the Offspring

Lillycrop, K. A., Phillips, E. S., Jackson, A. A., Hanson, M. A., & Burdge, G. C. (2005) · Journal of Nutrition · doi:10.1093/jn/135.6.1382 · Cited by 1,139 · see citing works

Influence of Maternal Obesity on the Long-Term Health of Offspring

Godfrey, K. M., Reynolds, R. M., Prescott, S. L., Nyirenda, M., Jaddoe, V. W. V., Eriksson, J. G., & Broekman, B. F. P. (2017) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(16)30107-3 · Cited by 1,059 · see citing works

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance: A Novel Murine Model of Developmental Programming

Samuelsson, A.-M., Matthews, P. A., Argenton, M., Christie, M. R., McConnell, J. M., Jansen, E. H. J. M., Piersma, A. H., Ozanne, S. E., Twinn, D. F., Remacle, C., et al. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.101477 · Cited by 923 · see citing works

DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status

Sinclair, K. D., Allegrucci, C., Singh, R., Gardner, D. S., Sebastian, S., Bispham, J., Thurston, A., Huntley, J. F., Rees, W. D., Maloney, C. A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707258104 · Cited by 812 · see citing works

Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension

Kwong, W. Y., Wild, A. E., Roberts, P., Willis, A. C., & Fleming, T. P. (2000) · Development · doi:10.1242/dev.127.19.4195 · Cited by 798 · see citing works

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryosPreprint

Messerschmidt, D. M., Knowles, B. B., & Solter, D. (2014) · Genes & Development · doi:10.1101/gad.234294.113 · Cited by 734 · see citing works

The Obstetric Origins of Health for a Lifetime

BARKER, D. J. P., & THORNBURG, K. L. (2013) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31829cb9ca · Cited by 634 · see citing works

DNA methylation signatures link prenatal famine exposure to growth and metabolism

Tobi, E. W., Goeman, J. J., Monajemi, R., Gu, H., Putter, H., Zhang, Y., Slieker, R. C., Stok, A. P., Thijssen, P. E., Müller, F., et al. (2014) · Nature Communications · doi:10.1038/ncomms6592 · Cited by 630 · see citing works

Impact of Body Mass Index Values on Sperm Quantity and Quality

Kort, H. I., Massey, J. B., Elsner, C. W., Mitchell‐Leef, D., Shapiro, D. B., Witt, M. A., & Roudebush, W. E. (2006) · Journal of Andrology · doi:10.2164/jandrol.05124 · Cited by 617 · see citing works

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F ₂ generation and alters the transcriptional profile of testis and sperm microRNA content

Fullston, T., Teague, E. M. C. O., Palmer, N. O., DeBlasio, M. J., Mitchell, M., Corbett, M., Print, C. G., Owens, J. A., & Lane, M. (2013) · The FASEB Journal · doi:10.1096/fj.12-224048 · Cited by 600 · see citing works

Culture of Preimplantation Mouse Embryos Affects Fetal Development and the Expression of Imprinted Genes1

Khosla, S., Dean, W., Brown, D., Reik, W., & Feil, R. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.3.918 · Cited by 560 · see citing works

Spermatozoal RNA profiles of normal fertile men

Ostermeier, G. C., Dix, D. J., Miller, D., Khatri, P., & Krawetz, S. A. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09899-9 · Cited by 516 · see citing works

Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

Dominguez-Salas, P., Moore, S. E., Baker, M. S., Bergen, A. W., Cox, S. E., Dyer, R. A., Fulford, A. J., Guan, Y., Laritsky, E., Silver, M. J., et al. (2014) · Nature Communications · doi:10.1038/ncomms4746 · Cited by 506 · see citing works

Insulin dependant diabetes mellitus: implications for male reproductive function

Agbaje, I., Rogers, D. A., McVicar, C. M., McClure, N., Atkinson, A. B., Mallidis, C., & Lewis, S. E. M. (2007) · Human Reproduction · doi:10.1093/humrep/dem077 · Cited by 482 · see citing works

Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes

Lambrot, R., Xu, C., Saint‐Phar, S., Chountalos, G., Cohen, T. R., Paquet, M., Suderman, M. J., Hallett, M. T., & Kimmins, S. (2013) · Nature Communications · doi:10.1038/ncomms3889 · Cited by 476 · see citing works

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

Igosheva, N., Abramov, A. Y., Poston, L., Eckert, J. J., Fleming, T. P., Duchen, M. R., & McConnell, J. M. L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010074 · Cited by 466 · see citing works

Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

Waterland, R. A., Kellermayer, R., Laritsky, E., Rayco‐Solon, P., Harris, R. A., Travisano, M., Zhang, W., Torskaya, M. S., Zhang, J., Shen, L., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001252 · Cited by 454 · see citing works

Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization.

Seli, E., Gardner, D., Schoolcraft, W., Moffatt, O. D., & Sakkas, D. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.12.039 · Cited by 420 · see citing works

Impact of stress on oocyte quality and reproductive outcome

Prasad, S., Tiwari, M., Pandey, A. N., Shrivastav, T. G., & Chaube, S. K. (2016) · Journal of Biomedical Science · doi:10.1186/s12929-016-0253-4 · Cited by 384 · see citing works

Cardiometabolic Differences in Children Born After in Vitro Fertilization: Follow-Up Study

Ceelen, M., van Weissenbruch, M. M., Vermeiden, J. P. W., van Leeuwen, F. E., & de Waal, H. A. D. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2432 · Cited by 383 · see citing works

Obese Women Exhibit Differences in Ovarian Metabolites, Hormones, and Gene Expression Compared with Moderate-Weight Women

Robker, R. L., Akison, L. K., Bennett, B. D., Thrupp, P. N., Chura, L. R., Russell, D. L., Lane, M., & Norman, R. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2648 · Cited by 382 · see citing works

The periconceptional period, reproduction and long-term health of offspring: the importance of one-carbon metabolism

Steegers-Theunissen, R. P. M., Twigt, J., Pestinger, V., & Sinclair, K. D. (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt041 · Cited by 378 · see citing works

Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring

Bromfield, J. J., Schjenken, J. E., Chin, P. Y., Care, A. S., Jasper, M. J., & Robertson, S. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305609111 · Cited by 374 · see citing works

Diet-Induced Obesity Model: Abnormal Oocytes and Persistent Growth Abnormalities in the Offspring

Jungheim, E. S., Schoeller, E. L., Marquard, K. L., Louden, E. D., Schaffer, J. E., & Moley, K. H. (2010) · Endocrinology · doi:10.1210/en.2010-0098 · Cited by 365 · see citing works

High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

Luzzo, K. M., Wang, Q., Purcell, S. H., Chi, M. M.-Y., Jimenez, P. T., Grindler, N. M., Schedl, T., & Moley, K. H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049217 · Cited by 356 · see citing works

Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development

Rivera, R. M., Stein, P., Weaver, J. R., Mager, J., Schultz, R. M., & Bartolomei, M. S. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm280 · Cited by 324 · see citing works

Systemic and Pulmonary Vascular Dysfunction in Children Conceived by Assisted Reproductive Technologies

Scherrer, U., Rimoldi, S. F., Rexhaj, E., Stüber, T., Duplain, H., Garcin, S., de Marchi, S. F., NICOD, P. H., Germond, M., Allemann, Y., et al. (2012) · Circulation · doi:10.1161/circulationaha.111.071183 · Cited by 295 · see citing works

Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells

Sharkey, D. J., Macpherson, A. M., Tremellen, K. P., & Robertson, S. A. (2007) · Molecular Human Reproduction · doi:10.1093/molehr/gam028 · Cited by 294 · see citing works

Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men

Hammoud, S. S., Nix, D. A., Hammoud, A. O., et al. (2011) · Human Reproduction · doi:10.1093/humrep/der192 · Cited by 291 · see citing works

The effect of paternal diet‐induced obesity on sperm function and fertilization in a mouse model

Bakos, H. W., Mitchell, M., Setchell, B. P., & Lane, M. (2010) · International Journal of Andrology · doi:10.1111/j.1365-2605.2010.01092.x · Cited by 290 · see citing works

Multigenerational epigenetic adaptation of the hepatic wound-healing response

Zeybel, M., Hardy, T., Wong, Y. K., Mathers, J. C., Fox, C. R., Gackowska, A., Oakley, F., Burt, A. D., Wilson, C. L., Anstee, Q. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2893 · Cited by 279 · see citing works

A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived spontaneously

Lazaraviciute, G., Kauser, M., Bhattacharya, S., Haggarty, P., & Bhattacharya, S. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu033 · Cited by 264 · see citing works

The maternal to zygotic transition in mammals

Li, L., Lu, X., & Dean, J. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2013.01.003 · Cited by 243 · see citing works

Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors

Bellver, J., Pellicer, A., García-Velasco, J. A., Ballesteros, A., Remohi, J. A., & Meseguer, M. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.06.001 · Cited by 235 · see citing works

Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology

Bakos, H. W., Henshaw, R. C., Mitchell, M., & Lane, M. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.11.044 · Cited by 230 · see citing works

Adaptive Responses by Mouse Early Embryos to Maternal Diet Protect Fetal Growth but Predispose to Adult Onset Disease1

Watkins, A. J., Ursell, E., Panton, R. W., Papenbrock, T., Hollis, L. J., Cunningham, C. M., Wilkins, A., Perry, V. H., Sheth, B., Kwong, W. Y., et al. (2007) · Biology of Reproduction · doi:10.1095/biolreprod.107.064220 · Cited by 227 · see citing works

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities

Leary, C., Leese, H. J., & Sturmey, R. G. (2014) · Human Reproduction · doi:10.1093/humrep/deu276 · Cited by 223 · see citing works

Impact of body mass index on seminal oxidative stress

Tunc, O., Bakos, H. W., & Tremellen, K. P. (2010) · Andrologia · doi:10.1111/j.1439-0272.2009.01032.x · Cited by 220 · see citing works

Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure

Watkins, A. J., Platt, D., Papenbrock, T., Wilkins, A., Eckert, J. J., Kwong, W. Y., Osmond, C., Hanson, M. A., & Fleming, T. P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610317104 · Cited by 219 · see citing works

Granulocyte-Macrophage Colony-Stimulating Factor Alleviates Adverse Consequences of Embryo Culture on Fetal Growth Trajectory and Placental Morphogenesis

Sjöblom, C., Roberts, C. T., Wikland, M., & Robertson, S. A. (2005) · Endocrinology · doi:10.1210/en.2004-1260 · Cited by 218 · see citing works

Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function

McPherson, N. O., Bakos, H. W., Owens, J. A., Setchell, B. P., & Lane, M. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00401.2011 · Cited by 218 · see citing works

Dietary patterns and semen quality in young men

Gaskins, A. J., Colaci, D., Mendiola, J., Swan, S. H., & Chavarro, J. E. (2012) · Human Reproduction · doi:10.1093/humrep/des298 · Cited by 215 · see citing works

Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes

Yang, X., Wu, L., Chura, L. R., Liang, X., Lane, M., Norman, R. J., & Robker, R. L. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.02.034 · Cited by 206 · see citing works

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

Silver, M. J., Kessler, N. J., Hennig, B. J., Domínguez-Salas, P., Laritsky, E., Baker, M. S., Coarfa, C., Hernández‐Vargas, H., Castelino, J. M., Routledge, M. N., et al. (2015) · Genome biology · doi:10.1186/s13059-015-0660-y · Cited by 191 · see citing works

Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring

Watkins, A. J., Wilkins, A., Cunningham, C. M., Perry, V. H., Seet, M. J., Osmond, C., Eckert, J. J., Torrens, C., Cagampang, F. R. A., Cleal, J. K., et al. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.149229 · Cited by 190 · see citing works

Sperm-derived histones contribute to zygotic chromatin in humans

van der Heijden, G. W., Ramos, L., Baart, E. B., van den Berg, I. M., Derijck, A. A. H. A., van der Vlag, J., Martini, E., & de Boer, P. (2008) · BMC Developmental Biology · doi:10.1186/1471-213x-8-34 · Cited by 181 · see citing works

Signaling in Cell Differentiation and MorphogenesisPreprint

Basson, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008151 · Cited by 176 · see citing works

Inter- and Intra-Individual Variation in Allele-Specific DNA Methylation and Gene Expression in Children Conceived using Assisted Reproductive Technology

Turan, N., Katari, S., Gerson, L. F., Chalian, R. A., Foster, M., Gaughan, J., Coutifaris, C., & Sapienza, C. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001033 · Cited by 171 · see citing works

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

Cropley, J. E., Eaton, S. A., Aiken, A., Young, P. E., Giannoulatou, E., Ho, J. W. K., Buckland, M. E., Keam, S. P., Hutvágner, G., Humphreys, D. T., et al. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.06.008 · Cited by 171 · see citing works

Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice

Watkins, A. J., & Sinclair, K. D. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00981.2013 · Cited by 164 · see citing works

Worldwide prevalence of adverse pregnancy outcomes among singleton pregnancies after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis

Qin, J., Sheng, X., Wu, D., Gao, S., You, Y., Yang, T.-B., & Wang, H. (2016) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-016-4250-3 · Cited by 163 · see citing works

Time to take human embryo culture seriously: Table I

Sunde, A., Brison, D. R., Dumoulin, J. C. M., Harper, J. C., Lundin, K., Magli, M. C., den Abbeel, E. V., & Veiga, A. (2016) · Human Reproduction · doi:10.1093/humrep/dew157 · Cited by 162 · see citing works

Blastocyst metabolism

Gardner, D. K., & Harvey, A. J. (2015) · Reproduction Fertility and Development · doi:10.1071/rd14421 · Cited by 162 · see citing works

Assisted Reproductive Technologies Are Associated With Cardiovascular Remodeling In Utero That Persists Postnatally

Valenzuela‐Alcaráz, B., Crispi, F., Bijnens, B. H., Cruz-Lemini, M., Creus, M. T., Sitges, M., Bartrons, J., Cı́vico, S., Balasch, J., & Gratacós, E. (2013) · Circulation · doi:10.1161/circulationaha.113.002428 · Cited by 161 · see citing works

Paternal diet-induced obesity impairs embryo development and implantation in the mouse

Mitchell, M., Bakos, H. W., & Lane, M. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.09.038 · Cited by 160 · see citing works

Differential effects of seasonality on preterm birth and intrauterine growth restriction in rural Africans1–4,

Rayco-Solon, P., Fulford, A. J., & Prentice, A. M. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.134 · Cited by 158 · see citing works

Influence of embryo culture medium (G5 and HTF) on pregnancy and perinatal outcome after IVF: a multicenter RCT

Kleijkers, S. H. M., Mantikou, E., Slappendel, E., Consten, D., van Echten‐Arends, J., Wetzels, A. M. M., van Wely, M., Smits, L. J. M., van Montfoort, A. P. A., Repping, S., et al. (2016) · Human Reproduction · doi:10.1093/humrep/dew156 · Cited by 150 · see citing works

The Early Origins of Obesity and Insulin Resistance: Timing, Programming and Mechanisms

Nicholas, L. M., Morrison, J. L., Rattanatray, L., Zhang, S., Ozanne, S. E., & McMillen, I. C. (2016) · International Journal of Obesity · doi:10.1038/ijo.2015.178 · Cited by 146 · see citing works

IVF culture medium affects post-natal weight in humans during the first 2 years of life

Kleijkers, S. H. M., van Montfoort, A. P. A., Smits, L. J. M., Viechtbauer, W., Roseboom, T. J., Nelissen, E. C. M., Coonen, E., Derhaag, J. G., Bastings, L., Schreurs, I. E. L., et al. (2014) · Human Reproduction · doi:10.1093/humrep/deu025 · Cited by 143 · see citing works

Transgenerational Inheritance of Glucose Intolerance in a Mouse Model of Neonatal Overnutrition

Pentinat, T., Ramon‐Krauel, M., Cebrià, J., Díaz, R., & Jiménez‐Chillarón, J. C. (2010) · Endocrinology · doi:10.1210/en.2010-0684 · Cited by 141 · see citing works

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity

Kühnen, P., Handke, D., Waterland, R. A., Hennig, B. J., Silver, M. J., Fulford, A. J., Domínguez-Salas, P., Moore, S. E., Prentice, A. M., Spranger, J., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.08.001 · Cited by 132 · see citing works

Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo

Bedzhov, I., Graham, S. J. L., Leung, C. Y., & Zernicka‐Goetz, M. (2014) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2013.0538 · Cited by 130 · see citing works

Differential RNAs in the sperm cells of asthenozoospermic patients

Jodar, M., Kalko, S. G., Castillo, J., et al. (2012) · Human Reproduction · doi:10.1093/humrep/des021 · Cited by 123 · see citing works

One-Cell Zygote Transfer from Diabetic to Nondiabetic Mouse Results in Congenital Malformations and Growth Retardation in Offspring

Wyman, A., Pinto, A., Sheridan, R. A., & Moley, K. H. (2007) · Endocrinology · doi:10.1210/en.2007-1273 · Cited by 122 · see citing works

Metabolic Induction and Early Responses of Mouse Blastocyst Developmental Programming following Maternal Low Protein Diet Affecting Life-Long Health

Eckert, J. J., Porter, R., Watkins, A. J., Burt, E., Brooks, S., Leese, H. J., Humpherson, P. G., Cameron, I. T., & Fleming, T. P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052791 · Cited by 119 · see citing works

Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin‐signaling pathways in the offspring

Nicholas, L. M., Rattanatray, L., MacLaughlin, S. M., Ozanne, S. E., Kleemann, D. O., Walker, S. K., Morrison, J. L., Zhang, S., Mühlhäusler, B. S., Martin‐Gronert, M. S., et al. (2013) · The FASEB Journal · doi:10.1096/fj.13-227918 · Cited by 115 · see citing works

Developmental biology: Support mothers to secure future public health

Barker, D. J. P., Barker, M. E., Fleming, T. P., & Lampl, M. (2013) · Nature · doi:10.1038/504209a · Cited by 106 · see citing works

Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice

Holland, M. L., Lowe, R., Caton, P. W., Gemma, C., Carbajosa, G., Danson, A. F., Carpenter, A. A. M., Loche, E., Ozanne, S. E., & Rakyan, V. K. (2016) · Science · doi:10.1126/science.aaf7040 · Cited by 106 · see citing works

Impact of Fetal and Infant Exposure to the Chinese Great Famine on the Risk of Hypertension in Adulthood

Wang, P.-X., Wang, J., Lei, Y.-X., Xiao, L., & Luo, Z. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049720 · Cited by 94 · see citing works

Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective

Ruebel, M. L., Cotter, M., Sims, C. R., Moutos, D. M., Badger, T. M., Cleves, M. A., Shankar, K., & Andres, A. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3524 · Cited by 89 · see citing works

In vitro fertilization availability and utilization in the United States: a study of demographic, social, and economic factors

Hammoud, A. O., Gibson, M., Stanford, J. B., White, G. L., Carrell, D. T., & Peterson, M. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.10.038 · Cited by 87 · see citing works

Paternal low protein diet programs preimplantation embryo gene expression, fetal growth and skeletal development in mice

Watkins, A. J., Sirovica, S., Stokes, B., Isaacs, M. A., Addison, O., & Martin, R. A. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.02.009 · Cited by 87 · see citing works

Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring

Williams, C. L., Teeling, J. L., Perry, V. H., & Fleming, T. P. (2011) · BMC Biology · doi:10.1186/1741-7007-9-49 · Cited by 85 · see citing works

Paternal under-nutrition programs metabolic syndrome in offspring which can be reversed by antioxidant/vitamin food fortification in fathers

McPherson, N. O., Fullston, T., Kang, W. X., Sandeman, L., Corbett, M. A., Owens, J. A., & Lane, M. (2016) · Scientific Reports · doi:10.1038/srep27010 · Cited by 85 · see citing works

The impact of specific fertility treatments on cognitive development in childhood and adolescence: a systematic review

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Do little embryos make big decisions? How maternal dietary protein restriction can permanently change an embryo's potential, affecting adult health

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