Cited by 57Statistical Methods in Clinical TrialsAdvanced Causal Inference TechniquesMeta-analysis and systematic reviews

Randomized study designs for lifestyle interventions: a tutorial

Younge, John O, Kouwenhoven-Pasmooij, Tessa A, Freak-Poli, Rosanne, Roos-Hesselink, Jolien W, Hunink, MG Myriam·2015·International Journal of Epidemiology

Abstract

Unhealthy lifestyle behaviours are considered modifiable risk factors for many diseases. Lifestyle interventions that target these behaviours need rigorous evaluation to assess their effectiveness. The randomized controlled trial is the study design of choice when it comes to the evaluation of interventions. However, lifestyle interventions are often complex and subject to several important issues, such as patient preference and non-adherence, that may threaten the internal and external validity of studies. There is a strong demand for high-quality randomized controlled trials of interventions that promote healthy lifestyle behaviours. With this tutorial we aim to provide guidance in the choice of an optimal randomized controlled trial design in future trials of lifestyle interventions.

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Crossref · 10.1093/ije/dyv183

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65 of 65 references verified0 citation errors · 0 not checkable

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Authors
Younge, J. O., Kouwenhoven-Pasmooij, T. A., Freak-Poli, R., Roos-Hesselink, J. W., & Hunink, M. M.
Affiliations
Erasmus MC (NL)
Venue
International Journal of Epidemiology
Published
2015-09-15
Volume
44
Issue
6
Pages
2006-2019
ISSN
  • 0300-5771 (ISSN-L)
  • 1464-3685
OpenAlex
W2265712261
Cited by
57
References
68
Citations by year
2026: 3 · 2025: 10 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 8 · 2020: 7 · 2019: 6 · 2018: 5 · 2017: 2 · 2015: 1
FWCI
0.45
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Keywords
lifestyle intervention, randomized controlled trial design, healthy lifestyle behaviours, modifiable risk factors, patient preferences, medication adherence, internal validity, generalizability
MeSH terms
Alcohol Drinking, Feeding Behavior, Humans, Life Style, Research Design, Exercise, Randomized Controlled Trials as Topic, Smoking Cessation, Evidence-Based Medicine, Risk Reduction Behavior

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