Cited by 177Pneumonia and Respiratory InfectionsMicrobial infections and disease researchInfluenza Virus Research Studies

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Bacterial adherence to pharyngeal cells during viral infection.

Fainstein, V., Musher, D. M., Cate, T. R.·1980·Journal of Infectious Diseases

DOI 10.1093/infdis/141.2.172

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Abstract

Adherence of bacteria to pharyngeal cells from patients with naturally acquired acute respiratory illness and from volunteers experimentally infected with influenza virus vaccine was studied. Increased adherence of Staphylococcus aureus was found in both groups. In addition, Haemophilus influenzae and Streptococcus pneumoniae type I adhered in increased numbers to cells from volunteers experimentally infected with influenza virus. Alterations in mucosal cells leading to increased bacterial adherence may play a role in the pathogenesis of suprainfection by these organisms in patients with viral respiratory diseases.

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Authors: Fainstein, V., Musher, D. M., & Cate, T. R.
Affiliations: Baylor College of Medicine (US)
Corresponding author: Musher, D. M.
ORCID: Musher, D. M.
Venue: Journal of Infectious Diseases
Publisher: Oxford University Press (OUP)
Published: 1980-02-01
Volume: 141
Issue: 2
Pages: 172-176
ISSN: 0022-1899 (ISSN-L)
1537-6613
DOI: 10.1093/infdis/141.2.172
OpenAlex: W2050875329
Cited by: 177
References: 12
Citations by year: 2024: 1 · 2023: 1 · 2022: 1 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 5 · 2016: 1 · 2015: 5 · 2014: 5 · 2013: 1 · 2012: 2
FWCI: 11.04
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Infectious Diseases (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
Keywords: bacterial adhesion, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, influenza virus, respiratory viral infections, mucosal changes, acute respiratory illness
MeSH terms: Adult, Bacterial Infections, Haemophilus influenzae, Humans, Influenza, Human, Influenza Vaccines, Influenza A virus, Pharynx, Respiratory Tract Infections, Staphylococcus aureus, Vaccines, Attenuated

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Bacterial adherence to pharyngeal cells during viral infection.

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