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Bacterial adherence to pharyngeal cells during viral infection.
Abstract
Adherence of bacteria to pharyngeal cells from patients with naturally acquired acute respiratory illness and from volunteers experimentally infected with influenza virus vaccine was studied. Increased adherence of Staphylococcus aureus was found in both groups. In addition, Haemophilus influenzae and Streptococcus pneumoniae type I adhered in increased numbers to cells from volunteers experimentally infected with influenza virus. Alterations in mucosal cells leading to increased bacterial adherence may play a role in the pathogenesis of suprainfection by these organisms in patients with viral respiratory diseases.
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“Influenza infection has been shown to increase the adherence of S. aureus (as well as H. influenzae and S. pneumoniae) to host pharyngeal cells (Fainstein et al., 1980).”
From Secondary bacterial infections associated with influenza pandemics (2017) · cites this paper as Fainstein et al., 1980
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Metadata
- Authors
- Fainstein, V., Musher, D. M., & Cate, T. R.
- Affiliations
- Baylor College of Medicine (US)
- Corresponding author
- Musher, D. M.
- ORCID
- Musher, D. M.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1980-02-01
- Volume
- 141
- Issue
- 2
- Pages
- 172-176
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2050875329
- Cited by
- 177
- References
- 12
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 5 · 2016: 1 · 2015: 5 · 2014: 5 · 2013: 1 · 2012: 2
- FWCI
- 11.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Keywords
- bacterial adhesion, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, influenza virus, respiratory viral infections, mucosal changes, acute respiratory illness
- MeSH terms
- Adult, Bacterial Infections, Haemophilus influenzae, Humans, Influenza, Human, Influenza Vaccines, Influenza A virus, Pharynx, Respiratory Tract Infections, Staphylococcus aureus, Vaccines, Attenuated
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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