Muscle mass and strength: Relation to function in population studies
Open accessAbstract
The use of the term sarcopenia to describe the age-related loss in skeletal muscle and its functional consequences is relatively recent. However, interest in the relationship of muscle mass to strength and function predates the concept of sarcopenia as researchers have attempted to understand differences in mass and strength between men and women, young and old. Most of these studies are cross-sectional comparisons in which muscle mass and strength tend to be linearly related, so that those with more muscle tend to be stronger. This article focuses instead on some potential problems with the sarcopenia-function association in old age and presents what little data exist from longitudinal population studies addressing the effect of sarcopenia over time.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Aging-associated decline in muscle mass contributes to low physical performance in older adults.
“Aging-associated decline in muscle mass contributes to the related low physical performance in older adults [3,4,5].”
From Effects of Protein Supplementation Combined with Exercise Intervention on Frailty Indices, Body Composition, and Physical Function in Frail Older Adults (2018) · cites this paper as [3]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
High-Intensity Strength Training in Nonagenarians: Effects on Skeletal Muscle
Fiatarone, M. A. (1990) · JAMA · doi:10.1001/jama.1990.03440220053029 · Cited by 1,593 · see citing works
Kallman, D. A., Plato, C. C., & Tobin, J. D. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.3.m82 · Cited by 629 · see citing works
Physical Performance Measures in Aging Research
Guralnik, J. M., Branch, L. G., Cummings, S. R., & Curb, J. D. (1989) · Journal of Gerontology · doi:10.1093/geronj/44.5.m141 · Cited by 564 · see citing works
Launer, L. J. (1994) · JAMA · doi:10.1001/jama.271.14.1093 · Cited by 487 · see citing works
Lean Body Mass-Body Fat Interrelationships in Humans
Forbes, G. B. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1987.tb02684.x · Cited by 342 · see citing works
Bassey, E. J., & Harries, U. (1993) · Clinical Science · doi:10.1042/cs0840331 · Cited by 318 · see citing works
Muscle Strength and Mobility as Predictors of Survival in 75–84 - Year - old People
Laukkanen, P., Heikkinen, E. M., & Kauppinen, M. (1995) · Age and Ageing · doi:10.1093/ageing/24.6.468 · Cited by 259 · see citing works
The Relationship between Muscle Mass and Muscle Strength in the Elderly
Reed, R. L., Pearlmutter, L., Yochum, K., Meredith, K. E., & Mooradian, A. D. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb03592.x · Cited by 237 · see citing works
Viitasalo, J. T., Era, P. A., Leskinen, A. ‐., & Heikkinen, E. M. (1985) · Ergonomics · doi:10.1080/00140138508963288 · Cited by 206 · see citing works
Avlund, K., Schroll, M., Davidsen, M., Løvborg, B., & Rantanen, T. (1994) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.1994.tb00403.x · Cited by 136 · see citing works
Muscle function in 75-year-old men and women. A longitudinal study.
ANIANSSON, A., Sperling, L., Rundgren, Å., & Lehnberg, E. (1983) · PubMed · Cited by 132 · see citing works
Compensatory muscle fiber hypertrophy in elderly men
ANIANSSON, A., Grimby, G., & Hedberg, M. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.73.3.812 · Cited by 112 · see citing works
Clement, F. J. (1974) · Journal of Gerontology · doi:10.1093/geronj/29.4.423 · Cited by 96 · see citing works
The quadriceps strength of healthy elderly people remeasured after eight years
Greig, C. A., Botella, J., & Young, A. (1993) · Muscle & Nerve · doi:10.1002/mus.880160103 · Cited by 73 · see citing works
Loss of muscle mass is poorly reflected in grip strength performance in healthy young men
JOHNSON, M. J., FRIEDL, K. E., FRYKMAN, P. N., & MOORE, R. J. (1994) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199402000-00015 · Cited by 63 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004 · see citing works
Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083 · see citing works
Self-citationPredictors of skeletal muscle mass in elderly men and women
Baumgartner, R. N., Waters, D. L., Gallagher, D., Morley, J. E., & Garry, P. J. (1999) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(98)00130-4 · Cited by 809 · see citing works
Accelerated Loss of Skeletal Muscle Strength in Older Adults With Type 2 Diabetes
Park, S. W., Goodpaster, B. H., Strotmeyer, E. S., Kuller, L. H., Broudeau, R., Kammerer, C., de Rekeneire, N., Harris, T. B., Schwartz, A. V., Tylavsky, F. A., et al. (2007) · Diabetes Care · doi:10.2337/dc06-2537 · Cited by 766 · see citing works
Self-citationFerrucci, L., Penninx, B. W. J. H., Volpato, S., Harris, T. B., Bandeen‐Roche, K., Balfour, J., Leveille, S. G., Fried, L. P., & Md, J. M. G. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50605.x · Cited by 618 · see citing works
Self-citationAndropause: clinical implications of the decline in serum testosterone levels with aging in men
Matsumoto, A. M. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.2.m76 · Cited by 490 · see citing works
Skeletal muscle and mortality results from the InCHIANTI study
Cesari, M., Pahor, M., Lauretani, F., Zamboni, V., Bandinelli, S., Bernabei, R., Guralnik, J. M., & Ferrucci, L. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gln031 · Cited by 346 · see citing works
Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women
Song, M.-Y., Ruts, E., Kim, J., Janumala, I., Heymsfield, S., & Gallagher, D. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.874 · Cited by 324 · see citing works
Cohen, P. G. (2001) · Medical Hypotheses · doi:10.1054/mehy.2000.1169 · Cited by 172 · see citing works
Shin, M. J., Jeon, Y. K., & Kim, I. J. (2018) · The World Journal of Men's Health · doi:10.5534/wjmh.180001 · Cited by 134 · see citing works
Insulin resistance and muscle strength in older persons
Abbatecola, A. M., Ferrucci, L., Ceda, G., Russo, C. R., Lauretani, F., Bandinelli, S., Barbieri, M., Valenti, G., & Paolisso, G. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.10.1278 · Cited by 135 · see citing works
Pulse wave velocity is associated with muscle mass decline: Health ABC study
study, F. T. H. A., Abbatecola, A. M., Chiodini, P., Gallo, C., Lakatta, E., Sutton-Tyrrell, K., Tylavsky, F. A., Goodpaster, B., de Rekeneire, N., Schwartz, A. V., et al. (2012) · AGE · doi:10.1007/s11357-011-9238-0 · Cited by 114 · see citing works
Self-citationLiao, C.-D., Lee, P.-H., Hsiao, D.-J., Huang, S.-W., Tsauo, J.-Y., Chen, H.-C., & Liou, T.-H. (2018) · Nutrients · doi:10.3390/nu10121916 · Cited by 94 · see citing works
- Authors
- Harris, T.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Harris, Tamara
- ORCID
- Harris, Tamara
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 1997-05
- Volume
- 127
- Issue
- 5
- Pages
- 1004S-1006S
- ISSN
- 0022-3166 (ISSN-L)
- OpenAlex
- W1891635962
- Cited by
- 122
- References
- 15
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 8 · 2023: 3 · 2022: 4 · 2021: 7 · 2020: 4 · 2019: 5 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 1 · 2013: 7 · 2012: 5
- FWCI
- 2.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Keywords
- sarcopenia, muscle mass, muscle strength, functional capacity, aging, long-term population study, sex differences, age-related muscle loss
- MeSH terms
- Aged, Body Weight, Female, Humans, Longitudinal Studies, Male, Muscular Atrophy, Muscle, Skeletal, Hand Strength
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
