Low-Fat Dietary Pattern among Postmenopausal Women Influences Long-Term Cancer, Cardiovascular Disease, and Diabetes Outcomes
Open accessAbstract
BACKGROUND: The preferred macronutrient dietary composition, and the health consequences of dietary fat reduction specifically, have been debated for decades. Here we provide a comprehensive overview of long-term health outcomes in the Women's Health Initiative Dietary Modification (DM) trial. OBJECTIVE: The DM trial aimed to examine whether a low-fat dietary pattern would reduce the risk of invasive breast cancer, colorectal cancer, and, secondarily, coronary heart disease (CHD), with various other health outcomes also considered. METHODS: The DM trial is a randomized controlled trial conducted at 40 centers in the US, among 48,835 postmenopausal women aged 50-79 y with baseline intake of ≥32% energy from fat. Participants were randomly assigned to a low-fat dietary pattern intervention group or to a usual-diet comparison group, during 1993-1998. Intervention goals were to reduce fat intake from ∼35% to 20% of total energy, in conjunction with increasing vegetables and fruit to 5 servings/d and grains to 6 servings/d. RESULTS: Over an 8.5-y (median) intervention period, intervention and comparison group differences included lower fat by 8-10%, and higher carbohydrate by 8-10%, of total energy, in conjunction with higher consumption of vegetables, fruit, and grains. Time-to-outcome analyses did not show significant differences between intervention and comparison groups for invasive breast cancer, colorectal cancer, or CHD, either over the intervention period or over longer-term cumulative follow-up. Additional analyses showed significant intervention group benefits related to breast cancer, CHD, and diabetes, without adverse effects. Over a 19.6-y (median) follow-up period, HRs (95% CIs) were 0.84 (0.74, 0.96) for breast cancer followed by death, and 0.87 (0.77, 0.98) for diabetes requiring insulin. CONCLUSIONS: Reduction in dietary fat with corresponding increase in vegetables, fruit, and grains led to benefits related to breast cancer, CHD, and diabetes, without adverse effects, among healthy postmenopausal US women. This trial was registered at clinicaltrials.gov as NCT00000611.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Low-fat patterns generally target total fat intake between 20% and 30% of kilocalories alongside other healthy dietary guidelines.
“Low-fat patterns generally target total fat intake between 20% and 30% of kilocalories alongside other healthy dietary guidelines.20,[29][30][31][32][33][34][35][36]”
From Popular dietary patterns: alignment with American Heart Association 2021 dietary guidance: a scientific statement from the American Heart Association. (2023) · cites this paper as [32]
Low-carbohydrate patterns generally refer to patterns with total carbohydrate targets between 20% and 40% of kilocalories.
“Low-carbohydrate patterns generally refer to patterns with total carbohydrate targets between 20% and 40% of kilocalaroies.20,[29][30][31][32][33][34][35][36]”
From Popular dietary patterns: alignment with American Heart Association 2021 dietary guidance: a scientific statement from the American Heart Association. (2023) · cites this paper as [32]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Body Fatness and Cancer — Viewpoint of the IARC Working Group
Lauby-Secretan, B., Scoccianti, C., Loomis, D., Grosse, Y., Bianchini, F., & Straif, K. (2016) · New England Journal of Medicine · doi:10.1056/nejmsr1606602 · Cited by 3,596 · see citing works
Design of the Women’s Health Initiative Clinical Trial and Observational Study
The Women’s Health Initiative Study Group (1998) · Controlled Clinical Trials · doi:10.1016/s0197-2456(97)00078-0 · Cited by 2,580 · see citing works
Dehghan, M., Mente, A., Zhang, X., Swaminathan, S., Li, W., Mohan, V., Iqbal, R., Kumar, R., Wentzel-Viljoen, E., Rosengren, A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32252-3 · Cited by 1,101 · see citing works
Howard, B. V., Van Horn, L., Hsia, J., Manson, J. E., Stefanick, M. L., Wassertheil-Smoller, S., Kuller, L. H., LaCroix, A. Z., Langer, R. D., Lasser, N. L., et al. (2006) · JAMA · doi:10.1001/jama.295.6.655 · Cited by 1,091 · see citing works
Self-citationPrentice, R. L., Caan, B., Chlebowski, R. T., Patterson, R., Kuller, L. H., Ockene, J. K., Margolis, K. L., Limacher, M. C., Manson, J. E., Parker, L. M., et al. (2006) · JAMA · doi:10.1001/jama.295.6.629 · Cited by 828 · see citing works
Self-citationDietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis
Seidelmann, S. B., Claggett, B., Cheng, S., Henglin, M., Shah, A., Steffen, L. M., Folsom, A. R., Rimm, E. B., Willett, W. C., & Solomon, S. D. (2018) · The Lancet Public Health · doi:10.1016/s2468-2667(18)30135-x · Cited by 776 · see citing works
Implementation of the women's health initiative study design
Anderson, G. L., Manson, J. E., Wallace, R. B., Lund, B., Hall, D., Davis, S., Shumaker, S. A., Wang, C., Stein, E. A., & Prentice, R. L. (2003) · Annals of Epidemiology · doi:10.1016/s1047-2797(03)00043-7 · Cited by 757 · see citing works
Self-citationSaturated fat, carbohydrate, and cardiovascular disease
Siri-Tarino, P. W., Sun, Q., Hu, F. B., & Krauss, R. M. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26285 · Cited by 636 · see citing works
Astrup, A., Dyerberg, J., Elwood, P., Hermansen, K., Hu, F. B., Jakobsen, M. U., Kok, F. J., Krauss, R. M., Lecerf, J. M., LeGrand, P., et al. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004622 · Cited by 487 · see citing works
Howard, B. V., Manson, J. E., Stefanick, M. L., Beresford, S. A., Frank, G., Jones, B., Rodabough, R. J., Snetselaar, L., Thomson, C., Tinker, L., et al. (2006) · JAMA · doi:10.1001/jama.295.1.39 · Cited by 426 · see citing works
Self-citationLow-Fat Dietary Pattern and Risk of Colorectal Cancer
Beresford, S. A. A., Johnson, K., Ritenbaugh, C., Lasser, N. L., Snetselaar, L. G., Black, H. R., Anderson, G. L., Assaf, A. R., Bassford, T. L., Bowen, D. J., et al. (2006) · JAMA · doi:10.1001/jama.295.6.643 · Cited by 402 · see citing works
Self-citationMargolis, K. L., Qi, L., Brzyski, R. G., Bonds, D. E., Howard, B. V., Kempainen, S., Liu, S., Robinson, J. G., Safford, M. M., Tinker, L., et al. (2008) · Clinical Trials · doi:10.1177/1740774508091749 · Cited by 266 · see citing works
Self-citationDietary fat: From foe to friend?
Ludwig, D. S., Willett, W. C., Volek, J. S., & Neuhouser, M. L. (2018) · Science · doi:10.1126/science.aau2096 · Cited by 257 · see citing works
Self-citationSacks, F. M., Carey, V. J., Anderson, C. A. M., Miller, E. R., Copeland, T., Charleston, J., Harshfield, B. J., Laranjo, N., McCarron, P., Swain, J., et al. (2014) · JAMA · doi:10.1001/jama.2014.16658 · Cited by 239 · see citing works
Prentice, R. L., Thomson, C. A., Caan, B. J., Hubbell, F. A., Anderson, G. L., Beresford, S. A. A., Pettinger, M. B., Lane, D. S., Lessin, L. S., Yasmeen, S., et al. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm159 · Cited by 212 · see citing works
Self-citationDietary Fat Reduction and Plasma Estradiol Concentration in Healthy Postmenopausal Women
Prentice, R. L., Thompson, D. M., Clifford, C. K., Gorbach, S. L., Goldwin, B., & Byar, D. P. (1990) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/82.2.129 · Cited by 171 · see citing works
Self-citationBorkman, M., Campbell, L. V., Chisholm, D. J., & Storlien, L. (1991) · Journal of Clinical Endocrinology and Metabolism · doi:10.1210/jcem-72-2-432 · Cited by 151 · see citing works
Chlebowski, R. T., Aragaki, A. K., Anderson, G. L., Thomson, C. A., Manson, J. E., Simon, M. S., Howard, B. V., Rohan, T. E., Snetselar, L., Lane, D. S., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.72.0326 · Cited by 137 · see citing works
Self-citationBeresford, S. A. A., Johnson, K., Ritenbaugh, C., Lasser, N. L., Snetsclaar, L. G., Black, H. R., Anderson, G. L., Assaf, A. R., Bassford, T. L., Bowen, D. J., et al. (2006) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000224608.12217.52 · Cited by 119 · see citing works
Self-citationPrentice, R. L., Aragaki, A. K., Van Horn, L., Thomson, C. A., Beresford, S. A., Robinson, J., Snetselaar, L., Anderson, G. L., Manson, J. E., Allison, M. A., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.153270 · Cited by 91 · see citing works
Self-citationAssociation of Low-Fat Dietary Pattern With Breast Cancer Overall Survival
Chlebowski, R. T., Aragaki, A. K., Anderson, G. L., Simon, M. S., Manson, J. E., Neuhouser, M. L., Pan, K., Stefanick, M. L., Rohan, T. E., Lane, D. S., et al. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2018.1212 · Cited by 87 · see citing works
Self-citationRock, C. L., Flatt, S. W., Pakiz, B., Quintana, E. L., Heath, D. D., Rana, B. K., & Natarajan, L. (2016) · Metabolism · doi:10.1016/j.metabol.2016.07.008 · Cited by 76 · see citing works
Zheng, C., Beresford, S. A. A., Horn, L. V., Tinker, L. F., Thomson, C. A., Neuhouser, M. L., Di, C., Manson, J. E., Mossavar‐Rahmani, Y., Seguin‐Fowler, R. A., et al. (2014) · American Journal of Epidemiology · doi:10.1093/aje/kwu152 · Cited by 61 · see citing works
Self-citationThomson, C. A., Horn, L. V., Caan, B. J., Aragaki, A. K., Chlebowski, R. T., Manson, J. E., Rohan, T. E., Tinker, L. F., Kuller, L. H., Hou, L., et al. (2014) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-0922 · Cited by 60 · see citing works
Self-citationHoward, B. V., Curb, J. D., Eaton, C. B., Kooperberg, C. L., Ockene, J. K., Kostis, J. B., Pettinger, M. B., Rajkovic, A., Robinson, J. G., Rossouw, J. E., et al. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28034 · Cited by 54 · see citing works
Self-citationHoward, B. V., Aragaki, A. K., Tinker, L. F., Allison, M., Hingle, M. D., Johnson, K., Manson, J. E., Shadyab, A. H., Shikany, J. M., Snetselaar, L. G., et al. (2017) · Diabetes Care · doi:10.2337/dc17-0534 · Cited by 39 · see citing works
Self-citationAllison, M., Aragaki, A. K., Ray, R. M., Margolis, K. L., Beresford, S. A. A., Kuller, L. H., O’Sullivan, M. J., Wassertheil-Smoller, S. W., & Horn, L. V. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpv196 · Cited by 27 · see citing works
Self-citationChlebowski, R. T., Anderson, G. L., Manson, J. E., Prentice, R. L., Aragaki, A. K., Snetselaar, L. G., Beresford, S. A. A., Kuller, L. H., Johnson, K., Lane, D. S., et al. (2018) · JNCI Cancer Spectrum · doi:10.1093/jncics/pky065 · Cited by 21 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300 · see citing works
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Alonso, A., Beaton, A. Z., Bittencourt, M. S., Boehme, A. K., Buxton, A. E., Carson, A. P., Commodore-Mensah, Y., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001052 · Cited by 5,987 · see citing works
Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000950 · Cited by 5,784 · see citing works
Martin, S. S., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Barone Gibbs, B., Beaton, A. Z., Boehme, A. K., et al. (2024) · Circulation · doi:10.1161/cir.0000000000001209 · Cited by 2,800 · see citing works
Martin, S. S., Aday, A. W., Allen, N. B., Almarzooq, Z., Anderson, C. A. M., Arora, P. K., Avery, C. L., Baker-Smith, C. M., Bansal, N., Beaton, A., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001303 · Cited by 1,206 · see citing works
American Cancer Society guideline for diet and physical activity for cancer prevention
Rock, C. L., Thomson, C., Gansler, T., Gapstur, S. M., McCullough, M. L., Patel, A. V., Andrews, K. S., Bandera, E. V., Spees, C. K., Robien, K., et al. (2020) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21591 · Cited by 789 · see citing works
Self-citationReduction in saturated fat intake for cardiovascular disease.
Hooper, L., Martin, N., Jimoh, O., Kirk, C., Foster, E., & Abdelhamid, A. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011737.pub3 · Cited by 42 · see citing works
Palaniappan, L. P., Allen, N. B., Almarzooq, Z., Anderson, C. A. M., Arora, P. K., Avery, C. L., Baker-Smith, C. M., Bansal, N., Currie, M. E., Earlie, R. S., et al. (2026) · Circulation · doi:10.1161/cir.0000000000001412 · Cited by 312 · see citing works
Reduction in saturated fat intake for cardiovascular disease
Hooper, L., Martin, N., Jimoh, O. F., Kirk, C., Foster, E., & Abdelhamid, A. S. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011737.pub2 · Cited by 228 · see citing works
Chlebowski, R. T., Aragaki, A. K., Anderson, G. L., Pan, K., Neuhouser, M. L., Manson, J. E., Thomson, C. A., Mossavar‐Rahmani, Y., Lane, D. S., Johnson, K., et al. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.19.00435 · Cited by 192 · see citing works
Self-citationThe Women’s Health Initiative Randomized Trials and Clinical Practice
Manson, J. E., Crandall, C. J., Rossouw, J. E., Chlebowski, R. T., Anderson, G. L., Stefanick, M. L., Aragaki, A. K., Cauley, J. A., Wells, G., LaCroix, A. Z., et al. (2024) · JAMA · doi:10.1001/jama.2024.6542 · Cited by 171 · see citing works
Self-citationGardner, C. D., Vadiveloo, M. K., Petersen, K. S., Anderson, C. A. M., Springfield, S., Van Horn, L., Khera, A., Lamendola, C., Mayo, S. M., Joseph, J. J., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001146 · Cited by 172 · see citing works
Patnode, C. D., Redmond, N., Iacocca, M. O., & Henninger, M. (2022) · JAMA · doi:10.1001/jama.2022.7408 · Cited by 89 · see citing works
Adipocyte Metabolism and Health after the Menopause: The Role of Exercise
Marsh, M. L., Oliveira, M. N., & Vieira‐Potter, V. J. (2023) · Nutrients · doi:10.3390/nu15020444 · Cited by 92 · see citing works
Efficacy of different dietary patterns on lowering of blood pressure level: an umbrella review.
Sukhato, K., Akksilp, K., Dellow, A., Vathesatogkit, P., & Anothaisintawee, T. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa252 · Cited by 38 · see citing works
Nielsen, C. H., Yan, H., Nguyen, D. N., Ahnfeldt, A. M., Burrin, D. G., Hartmann, B., Heckmann, A. B., Sangild, P. T., Thymann, T., & Bering, S. B. (2020) · Nutrients · doi:10.3390/nu12010245 · Cited by 46 · see citing works
Lifestyle interventions for cardiometabolic health
Rutters, F., den Braver, N. R., Lakerveld, J., Mackenbach, J. D., van der Ploeg, H. P., Griffin, S. J., Elders, P. J. M., & Beulens, J. W. J. (2024) · Nature Medicine · doi:10.1038/s41591-024-03373-0 · Cited by 39 · see citing works
Biomarker-Calibrated Macronutrient Intake and Chronic Disease Risk among Postmenopausal Women
Prentice, R. L., Pettinger, M. B., Neuhouser, M. L., Raftery, D., Zheng, C., Gowda, G. A. N., Huang, Y., Tinker, L. F., Howard, B. V., Manson, J. E., et al. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab091 · Cited by 37 · see citing works
Self-citationDietary patterns and breast cancer risk, prognosis, and quality of life: A systematic review
Bu, Y., Qu, J., Ji, S., Zhou, J., Xue, M., Qu, J., Sun, H., & Liu, Y. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1057057 · Cited by 29 · see citing works
Vieira, L. M., Gottschall, C. B. A., Vinholes, D. B., Martínez‐González, M. Á., & Marcadenti, A. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2020.06.018 · Cited by 27 · see citing works
Pan, K., Aragaki, A. K., Neuhouser, M. L., Simon, M. S., Luo, J., Caan, B. J., Snetselaar, L. G., Mortimer, J. E., Manson, J. E., Kroenke, C. H., et al. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01379-w · Cited by 26 · see citing works
Self-citationXue, W., Jin, Q., & Wang, X. (2023) · Nutrients · doi:10.3390/nu15194214 · Cited by 30 · see citing works
Associations of lower-carbohydrate and lower-fat diets with mortality among people with prediabetes
Li, L., Shan, Z., Wan, Z., Li, R., Geng, T., Lu, Q., Zhu, K., Qiu, Z., Zhang, X., Liu, Y., et al. (2022) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqac058 · Cited by 26 · see citing works
Nutritional epidemiology and the Women’s Health Initiative: a review
Prentice, R. L., Howard, B. V., Horn, L. V., Neuhouser, M. L., Anderson, G. L., Tinker, L. F., Lampe, J. W., Raftery, D., Pettinger, M. B., Aragaki, A. K., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab091 · Cited by 22 · see citing works
Self-citationPeila, R., Xue, X., Cauley, J. A., Chlebowski, R. T., Manson, J. E., Nassir, R., Saquib, N., Shadyab, A. H., Zhang, Z., Wassertheil-Smoller, S. W., et al. (2021) · JNCI Cancer Spectrum · doi:10.1093/jncics/pkab072 · Cited by 20 · see citing works
Self-citationWang, H., Huang, L., Lin, L., Chen, X., Zhong, C., Li, Q., Li, N., Gao, D., Zhou, X., Chen, R., et al. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521000234 · Cited by 20 · see citing works
Salemi, F., Beigrezaei, S., Arabi, V., Zahir, S. T., & Salehi‐Abargouei, A. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-03034-3 · Cited by 16 · see citing works
Dong, H., Kong, X., Wang, X., Liu, Q., Fang, Y., & Wang, J. (2023) · Nutrients · doi:10.3390/nu15112586 · Cited by 16 · see citing works
Ma, J., Hu, D., Li, D., Chen, Y., Chen, Q., Fan, Z., Wang, G., Xu, W., Zhu, G., Xin, Z., et al. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105002 · Cited by 15 · see citing works
Noakes, T. D. (2021) · Open Heart · doi:10.1136/openhrt-2021-001680 · Cited by 18 · see citing works
Prentice, R. L., Vasan, S., Tinker, L. F., Neuhouser, M. L., Navarro, S. L., Raftery, D., Gowda, G. N., Pettinger, M. B., Aragaki, A. K., Lampe, J. W., et al. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.05.021 · Cited by 13 · see citing works
Self-citationTalebi, S., Zeraattalab-Motlagh, S., Rahimlou, M., Sadeghi, E., Rashedi, M. H., Ghoreishy, S. M., & Mohammadi, H. (2024) · Nutrition Reviews · doi:10.1093/nutrit/nuae033 · Cited by 13 · see citing works
Peng, L., Xiang, L., Xu, Z., Gu, H., Zhu, Z., Tang, Y., Jiang, Y., He, H., Wang, Y., & Zhao, X. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1013643 · Cited by 12 · see citing works
Stasiewicz, B., Wądołowska, L., Biernacki, M., Słowińska, M. A., & Stachowska, E. (2022) · Cancers · doi:10.3390/cancers14071724 · Cited by 10 · see citing works
Han, A., & Choi, Y. J. (2024) · Nutrients · doi:10.3390/nu16070967 · Cited by 9 · see citing works
Dietary Patterns and Breast, Colorectal, Lung, and Prostate Cancer: A Systematic Review
Boushey, C. J., Ard, J. D., Bazzano, L., Heymsfield, S. B., Mayer‐Davis, E. J., Sabaté, J., Snetselaar, L. G., Horn, L. V., Schneeman, B. O., English, L., et al. (2020) · doi:10.52570/nesr.dgac2020.sr0104 · Cited by 9 · see citing works
Self-citationTian, Q., Lin, L., Shan, Z., Lu, Q., Li, R., Liu, S., Lin, X., Li, R., Chen, X., Ou, Y., et al. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.03.011 · Cited by 8 · see citing works
Neuhouser, M. L., Wertheim, B. C., Perrigue, M. M., Hingle, M. D., Tinker, L. F., Shikany, J. M., Johnson, K., Waring, M. E., Seguin‐Fowler, R. A., Vitolins, M. Z., et al. (2020) · Current Developments in Nutrition · doi:10.1093/cdn/nzaa126 · Cited by 8 · see citing works
Self-citationPrentice, R. L., Pettinger, M. B., Neuhouser, M. L., Raftery, D., Zheng, C., Gowda, G. A. N., Huang, Y., Tinker, L. F., Howard, B. V., Manson, J. E., et al. (2022) · American Journal of Epidemiology · doi:10.1093/aje/kwac017 · Cited by 7 · see citing works
Self-citationFeng, Q., Yang, M., Dong, H., Sun, H., Chen, S., Chen, C., Zhang, Y., Lan, X., Su, D., & Zeng, G. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522002422 · Cited by 7 · see citing works
Rogers, C. J., Petersen, K. H., & Kris‐Etherton, P. M. (2022) · Medical Clinics of North America · doi:10.1016/j.mcna.2022.06.001 · Cited by 7 · see citing works
Sauter, E. R., Butera, G., & Agurs‐Collins, T. (2024) · Cancers · doi:10.3390/cancers16193296 · Cited by 6 · see citing works
Peng, L., Du, Q., Xiang, L., Gu, H., Luo, H., Xu, Z., He, H., Xia, B., Zhou, Z., Wang, Y., et al. (2024) · The journal of nutrition health & aging · doi:10.1016/j.jnha.2024.100240 · Cited by 6 · see citing works
Can precision medicine get us through menopause?
Vieira‐Potter, V. J. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104362 · Cited by 4 · see citing works
Aguilera-Buenosvinos, I., Martínez‐González, M. Á., Zazpe, I., Romanos-Nanclares, A., Sánchez-Bayona, R., & Toledo, E. (2023) · Nutrition · doi:10.1016/j.nut.2022.111967 · Cited by 2 · see citing works
Sun, W., Gao, Q., Tang, S., Sun, Y., Kang, X., Jiang, L., Zhao, X., Li, Z., An, X., Ji, H., et al. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuaf250 · Cited by 1 · see citing works
Nguyen, N. Q., Ta, K.-N. T., & Chuang, K.-J. (2026) · Cerebrovascular Diseases · doi:10.1159/000550330 · Cited by 2 · see citing works
Change to a Higher Carbohydrate Diet and Energy Expenditure among Postmenopausal Women
Prentice, R. L., Neuhouser, M. L., Tinker, L. F., & Howard, B. V. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab095 · Cited by 1 · see citing works
Self-citationReply to R.T. Chlebowski et al
Ligibel, J. A. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.01456 · Cited by 1 · see citing works
Reply to WC Willett and D Ludwig
Prentice, R. L., Howard, B. V., Horn, L. V., Manson, J. E., & Chlebowski, R. T. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab314
Self-citationA framework for predicting consumers’ sustainable purchase in COVID era
ابراهيم, ر. ش. ا., & محمود, ر. م. م. (2022) · التجارة والتمويل · doi:10.21608/caf.2022.251784
Weight Management, Micronutrients, and Supplements in Diabetes
Roberts, E., & Mechanick, J. I. (2022) · EMJ Diabetes · doi:10.33590/emjdiabet/10153468
Barbaresko, J., Lang, A. S., Szczerba, E., Bächle, C., Beckhaus, J., Schwingshackl, L., Neuenschwander, M., & Schlesinger, S. (2023) · doi:10.2337/figshare.21561987.v1
Diet and Chronic Disease Research in the Women’s Health Initiative
Prentice, R. L. (2023) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2023.11.012
Self-citationHow the Microbiome Affects the Risk for Colon Cancer
Drewes, J. L., & Bhatt, A. P. (2023) · Springer eBooks · doi:10.1007/978-3-031-46712-7_7
Alshamrani, H., Miskeen, E., & Alshomrany, A. (2024) · Cureus · doi:10.7759/cureus.55307
Dietary habits and breast cancer in South Asian women: a systematic review protocol
Seneviwickrama, M., Dilhani, W. N. S., Jayakody, S., Denagamagei, S. S., & Nawaratne, S. D. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-087661
Effects of Lifestyle Interventions on Metabolic Dysfunction-Associated Steatotic Liver Disease
Sharma, A. R., & Barb, D. (2025) · Springer eBooks · doi:10.1007/978-3-031-82888-1_10
Li, W., Zhang, Z., Tang, A., Huang, H., Yao, W., Chen, M., & Zou, T. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuaf074
Macronutrient content and quality, and risk of multimorbidity in the UK Biobank
Vázquez‐Fernández, A., Yévenes‐Briones, H., Baylín, A., Caballero, F. F., & López‐García, E. (2025) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaf267
Huang, Y., xiu-de, L., Zhang, B., Hu, H., & Tang, Z. (2025) · British Journal Of Nutrition · doi:10.1017/s0007114525105904
The interplay between lipid metabolism, cancer progression and anti-cancer immunity
Koh, C., Lee, Y., Kim, I., & Chung, Y. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-026-01783-3
- Authors
- Prentice, R. L., Aragaki, A. K., Howard, B. V., Chlebowski, R. T., Thomson, C. A., Van Horn, L., Tinker, L. F., Manson, J. E., Anderson, G. L., Kuller, L. E., Neuhouser, M. L., Johnson, K. C., Snetselaar, L., & Rossouw, J. E.
- Affiliations
- Fred Hutch Cancer Center (US)
- Georgetown University Medical Center (US)
- The Lundquist Institute (US)
- University of Arizona (US)
- Brigham and Women's Hospital (US)
- University of Tennessee Health Science Center (US)
- University of Iowa (US)
- National Heart, Lung, and Blood Institute (US)
- Corresponding author
- Prentice, Ross L
- ORCID
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 149
- Issue
- 9
- Pages
- 1565-1574
- ISSN
- 0022-3166 (ISSN-L)
- PMC
- PMC6736441
- OpenAlex
- W2971070863
- Cited by
- 62
- References
- 28
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 12 · 2021: 9 · 2020: 10
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Nutrition (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (HHSN268201600018C, HHSN268201600001C, HHSN268201600002C, HHSN268201600003C, HHSN268201600004C)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Keywords
- dietary fat reduction, postmenopausal women, breast cancer, colorectal cancer, coronary artery disease, diabetes mellitus, type 1 diabetes, fruit and vegetable intake, grain consumption, macronutrient composition, Women's Health Initiative Dietary Modification Trial, long-term health effects
- MeSH terms
- Aged, Breast Neoplasms, Coronary Disease, Diabetes Mellitus, Female, Humans, Middle Aged, Colorectal Neoplasms, Women's Health, Postmenopause, Diet, Fat-Restricted
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
