Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons
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Neuron depolarization induces release of EVs containing high amounts of miRNAs.
“Neuron depolarization has been shown to induce release of EVs containing high amounts of miRNAs, and miRNA elimination has been proposed to promote rapid translation of proteins required for synaptic plasticity [31].”
From Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations (2018) · cites this paper as [31]
miRNA elimination promotes rapid translation of proteins required for synaptic plasticity.
“Neuron depolarization has been shown to induce release of EVs containing high amounts of miRNAs, and miRNA elimination has been proposed to promote rapid translation of proteins required for synaptic plasticity [31].”
From Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations (2018) · cites this paper as [31]
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Exosomes are released by cultured cortical neurones
Fauré, J., Lachenal, G., Court, M., Hirrlinger, J., Chatellard-Causse, C., Blot, B., Grange, J., Schoehn, G., Goldberg, Y., Boyer, V., et al. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.12.003 · Cited by 896 · see citing works
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- Authors
- Goldie, B. J., Dun, M. D., Lin, M., Smith, N. D., Verrills, N. M., Dayas, C. V., & Cairns, M. J.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-07-22
- Volume
- 42
- Issue
- 14
- Pages
- 9195-9208
- ISSN
- 0305-1048
- 1362-4962
- PMC
- PMC4132720
- Cited by
- 294
- References
- 1
- Language
- en
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