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Nutritional interventions in treating menopause-related sleep disturbances: a systematic review

Polasek, Dominik, Santhi, Nayantara, Alfonso-Miller, Pamela, Walshe, Ian H, Haskell-Ramsay, Crystal F, Elder, Greg J·2024·Nutrition Reviews

Abstract

Context: Sleep disturbances are a core symptom of menopause, which refers to the permanent cessation of menstrual periods. Nutritional interventions may alleviate menopause-related sleep disturbances, as studies have shown that certain interventions (eg, tart cherry juice, or tryptophan-rich foods) can improve relevant aspects of sleep. Objective: The aim of this systematic review was to examine the effect of nutritional interventions for menopause-related sleep disturbances, in order to inform the subsequent development of specific interventional trials and assess their potential as a treatment for menopause-related sleep disturbances. Data Sources: Published studies in English were located by searching PubMed and PsycArticles databases (until September 15, 2022). Data Extraction: Following full-text review, a final total of 59 articles were included. The search protocol was performed in accordance with PRISMA guidelines. Data Analysis: A total of 37 studies reported that a nutritional intervention improved some aspect of sleep, and 22 studies observed no benefit. Most (n = 24) studies recruited postmenopausal women, 18 recruited menopausal women, 3 recruited perimenopausal women, and 14 recruited women from multiple groups. The majority of the studies were of low methodological quality. Due to the heterogeneity of the studies, a narrative synthesis without meta-analysis is reported. Conclusion: Despite the large heterogeneity in the studies and choice of intervention, the majority of the identified studies reported that a nutritional intervention did benefit sleep, and that it is mainly subjective sleep that is improved. More high-quality, adequately powered, randomized controlled trials of the identified nutritional interventions are necessary. Systematic Review Registration: PROSPERO registration no. CRD42021262367.

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Metadata

Authors
Polasek, D., Santhi, N., Alfonso-Miller, P., Walshe, I. H., Haskell-Ramsay, C. F., & Elder, G. J.
Affiliations
  • Northumbria Sleep Research, Northumbria University , Newcastle upon Tyne, UK
  • Department of Sport, Exercise and Rehabilitation, Northumbria University , Newcastle, UK
  • Department of Psychology, Faculty of Health and Life Sciences, Northumbria University , Newcastle upon Tyne, UK
Venue
Nutrition Reviews
Published
2023-09-11
Volume
82
Issue
8
Pages
1087-1110
ISSN
  • 0029-6643
  • 1753-4887
Cited by
10
References
7
Language
en
Funders
Northumbria University Graduate Futures

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Polasek, D., Santhi, N., Alfonso-Miller, P., Walshe, I. H., Haskell-Ramsay, C. F., & Elder, G. J. (2024). Nutritional interventions in treating menopause-related sleep disturbances: a systematic review. Nutrition Reviews. https://doi.org/10.1093/nutrit/nuad113

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