The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
The aging clock: circadian rhythms and later life
Open accessAbstract
Circadian rhythms play an influential role in nearly all aspects of physiology and behavior in the vast majority of species on Earth. The biological clockwork that regulates these rhythms is dynamic over the lifespan: rhythmic activities such as sleep/wake patterns change markedly as we age, and in many cases they become increasingly fragmented. Given that prolonged disruptions of normal rhythms are highly detrimental to health, deeper knowledge of how our biological clocks change with age may create valuable opportunities to improve health and longevity for an aging global population. In this Review, we synthesize key findings from the study of circadian rhythms in later life, identify patterns of change documented to date, and review potential physiological mechanisms that may underlie these changes.
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Epidemiology of the human circadian clock
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Cited by
Ageing hallmarks exhibit organ-specific temporal signatures
Schaum, N., Lehallier, B., Hahn, O., Pálovics, R., Hosseinzadeh, S., Lee, S. E., Sit, R., Lee, D. P., Losada, P. M., Zardeneta, M. E., et al. (2020) · Nature · doi:10.1038/s41586-020-2499-y · Cited by 671
Circadian rhythms and the molecular clock in cardiovascular biology and disease
Crnko, S., Du Pré, B. C., Sluijter, J. P. G., & Van Laake, L. W. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0167-4 · Cited by 499
Correa-de-Araujo, R., Addison, O., Miljkovic, I., Goodpaster, B. H., Bergman, B. C., Clark, R. V., Elena, J. W., Esser, K. A., Ferrucci, L., Harris-Love, M. O., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00963 · Cited by 468
Circadian disruption: what do we actually mean?
Vetter, C. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14255 · Cited by 333
NAD metabolism: Implications in aging and longevity
Yaku, K., Okabe, K., & Nakagawa, T. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.05.006 · Cited by 269
Metadata
- Authors
- Hood, S., & Amir, S.
- Venue
- Journal of Clinical Investigation
- Published
- 2017-02-01
- Volume
- 127
- Issue
- 2
- Pages
- 437-446
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- OpenAlex
- W2585664795
- Cited by
- 605
- References
- 31
- FWCI
- 16.26
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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