The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Sleep Neurobiology from a Clinical Perspective
Open accessAbstract
Many neurochemical systems interact to generate wakefulness and sleep. Wakefulness is promoted by neurons in the pons, midbrain, and posterior hypothalamus that produce acetylcholine, norepinephrine, dopamine, serotonin, histamine, and orexin/hypocretin. Most of these ascending arousal systems diffusely activate the cortex and other forebrain targets. NREM sleep is mainly driven by neurons in the preoptic area that inhibit the ascending arousal systems, while REM sleep is regulated primarily by neurons in the pons, with additional influence arising in the hypothalamus. Mutual inhibition between these wake- and sleep-regulating regions likely helps generate full wakefulness and sleep with rapid transitions between states. This up-to-date review of these systems should allow clinicians and researchers to better understand the effects of drugs, lesions, and neurologic disease on sleep and wakefulness.
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Neurons containing hypocretin (orexin) project to multiple neuronal systems
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VTA dopaminergic neurons regulate ethologically relevant sleep-wake behaviors
Eban-Rothschild, A., Rothschild, G., Giardino, W. J., Jones, J. R., & de Lecea, L. (2016) · Nature Neuroscience · doi:10.1038/nn.4377 · Cited by 583
Diet promotes sleep duration and quality
Peuhkuri, K., Sihvola, N., & Korpela, R. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.03.009 · Cited by 470
Bathory, E., & Tomopoulos, S. (2017) · Current Problems in Pediatric and Adolescent Health Care · doi:10.1016/j.cppeds.2016.12.001 · Cited by 382
Neuronal Mechanisms for Sleep/Wake Regulation and Modulatory Drive
Eban-Rothschild, A., Appelbaum, L., & de Lecea, L. (2018) · Neuropsychopharmacology · doi:10.1038/npp.2017.294 · Cited by 282
Orexin System: The Key for a Healthy Life
Chieffi, S., Carotenuto, M., Monda, V., Valenzano, A., Villano, I., Precenzano, F., Tafuri, D., Salerno, M., Filippi, N., Nuccio, F., et al. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00357 · Cited by 224
Metadata
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-07-01
- Volume
- 34
- Issue
- 7
- Pages
- 845-58
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W2100600420
- Cited by
- 277
- References
- 35
- FWCI
- 10.70
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
