Sleep and Nutrition Interactions: Implications for Athletes
Open accessAbstract
This narrative review explores the relationship between sleep and nutrition. Various nutritional interventions have been shown to improve sleep including high carbohydrate, high glycaemic index evening meals, melatonin, tryptophan rich protein, tart cherry juice, kiwifruit and micronutrients. Sleep disturbances and short sleep duration are behavioural risk factors for inflammation, associated with increased risk of illness and disease, which can be modified to promote sleep health. For sleep to have a restorative effect on the body, it must be of adequate duration and quality; particularly for athletes whose physical and mental recovery needs may be greater due to the high physiological and psychological demands placed on them during training and competition. Sleep has been shown to have a restorative effect on the immune system, the endocrine system, facilitate the recovery of the nervous system and metabolic cost of the waking state and has an integral role in learning, memory and synaptic plasticity, all of which can impact both athletic recovery and performance. Functional food-based interventions designed to enhance sleep quality and quantity or promote general health, sleep health, training adaptations and/or recovery warrant further investigation.
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TL;DR
This narrative review examines interactions between sleep and nutrition, with a focus on implications for athlete recovery and performance. It concludes that several nutritional interventions may improve sleep, but evidence in athletic populations remains limited and requires further investigation.
Key findings
- Nutritional factors reported to affect sleep include high-carbohydrate/high-glycaemic-index evening meals, melatonin, tryptophan-rich protein, tart cherry juice, kiwifruit, and micronutrients such as B vitamins and magnesium.
- A high-GI meal consumed four hours before bed significantly reduced sleep onset latency (9.0 ± 6.2 min) compared with a low-GI meal (17.5 ± 6.2 min) and the same meal consumed one hour before bed (14.6 ± 9.9 min; p = 0.009).
- Tart cherry juice supplementation increased time in bed (+24 min), total sleep duration (+34 min), sleep efficiency (82.3%), and reduced daytime napping (–22%) (p < 0.05); in older females with insomnia (n = 7), it reduced insomnia severity index scores and wake after sleep onset.
- In athletes, sleep disturbances are common: professional male ice hockey players (n = 23) had mean total sleep duration of 6.92 h (95% CI 6.3–7.5 h), and 66% of elite German athletes (n = 632) reported pre-competition insomnia symptoms; sleep duration <8 h was the strongest predictor of injury in adolescent athletes (RR = 2.1; 95% CI 1.2–3.9).
Methods
- Narrative review; no systematic search strategy, inclusion/exclusion criteria, or meta-analytic synthesis is described.
- Synthesizes existing literature on sleep physiology, sleep in athletes, and nutritional interventions including carbohydrate, melatonin, tryptophan-rich protein, antioxidants, tart cherry, kiwifruit, B vitamins, and magnesium.
- Draws on studies with varied designs and populations, including athletes (e.g., n = 23 ice hockey players; n = 632 German athletes), healthy adults, older adults, and some animal evidence.
Limitations
- The paper states that further research is warranted, particularly in athletic populations, and that the effects of tryptophan-rich protein interventions, antioxidant recovery-promoting doses, and food-based sleep interventions require more investigation.
- The paper notes that the kiwifruit study lacked a control group, had a high dropout rate (n = 5), and recruited subjects interested in a dietary sleep intervention, which may bias findings.
- Evident from the text: as a narrative review, it lacks systematic quality appraisal; conclusions rely on heterogeneous studies, several small samples (e.g., n = 6, n = 7, n = 14, n = 25, n = 43), and some animal or mechanistic evidence, so causality and generalizability to athletes are not established.
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Claims the paper makes
0 of 142 cited sources checked · 0 supported · 0 flagged
- Premisenone given
Various nutritional interventions improve sleep, including high carbohydrate, high glycaemic index evening meals, melatonin, tryptophan rich protein, tart cherry juice, kiwifruit and micronutrients.
“Various nutritional interventions have been shown to improve sleep including high carbohydrate, high glycaemic index evening meals, melatonin, tryptophan rich protein, tart cherry juice, kiwifruit and micronutrients.”
Quote in the paperNot a substantial claim - Premisecitation
For sleep to have a restorative effect on the body, it must be of adequate duration and quality.
“For sleep to have a restorative effect on the body, it must be of adequate duration and quality; particularly for athletes whose physical and mental recovery needs may be greater due to the high physiological and psychological demands placed on them during training and competition.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [28] Samuels, 2016, The Athlete Sleep Screening Questionnaire: A new tool for assessing and managing sleep in elite athletes, Br. J. Sports Med. source
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- cites [42] Hirshkowitz, 2015, National Sleep Foundation’s sleep time duration recommendations: Methodology and results summary, Sleep Health source
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- Premisecitation
A high glycaemic index evening meal reduces sleep onset latency.
“Nutrients such as carbohydrate (high glycaemic index evening meal reduced sleep onset latency)”
Quote in the paperNot a substantial claim0 of 2 sources checked - Premisecitation
Inadequate recovery can reduce autonomic nervous system resources, with an associated reduction in heart rate variability and increased resting heart rate.
“Inadequate recovery can reduce autonomic nervous system (ANS) resources, with an associated reduction in heart rate variability (HRV) and increased resting heart rate [30].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [30] Hynynen, 2006, Heart rate variability during night sleep and after awakening in overtrained athletes, Med. Sci. Sports Exerc. source
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- Premisecitation
Process C can be modified by exogenous cues.
“Give that Process C can be modified by exogenous cues [27], there is scope for investigation of nutrition interventions to enhance sleep quality and quantity.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [27] Johnston, 2014, Physiological links between circadian rhythms, metabolism and nutrition, Exp. Physiol. source
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- Premisecitation
Ethanol reduces REM sleep.
“ethanol (reduced REM sleep) [37]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [37] Jeukendrup, 2017, Periodized Nutrition for Athletes, Sports Med. source
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- Premisecitation
Sleep was self-reported as the most important recovery modality by South African athletes (n = 890; international n = 183, national n = 474, club n = 233).
“Similarly, sleep was self-reported as the most important recovery modality utilised by South African athletes (n = 890; international n = 183, national n = 474, club n = 233) [15].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [15] Venter, 2012, Role of sleep in performance and recovery of athletes: A review article, South Afr. J. Res. Sport Phys. Educ. Recreat.
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- Premisecitation
Sleep duration (<8 h) has been identified as the strongest predictor of injury in adolescent athletes (RR = 2.1; 95% CI: 1.2-3.9).
“Sleep duration (< 8 h) has been identified as the strongest predictor of injury in adolescent athletes (RR = 2.1; 95% CI: 1.2–3.9) [34].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [34] Milewski, 2014, Chronic lack of sleep is associated with increased sports injuries in adolescent athletes, J. Paediatr. Orthop. source
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- Premisecitation
Professional male ice hockey players (n = 23) had a mean total sleep duration of 6.92 h (95% CI 6.3-7.5 h) measured by polysomnography.
“Assessment of the sleep patterns of professional male ice hockey players (n = 23) using polysomnography (PSG), demonstrated mean total sleep duration was 6.92 h; 95% CI 6.3–7.5 h [32].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [32] Tuomilehto, 2017, Sleep of professional athletes: Underexploited potential to improve health and performance, J. Sports Sci. source
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- Interpretationcitation
Sleep deprivation factors may negatively impact an athlete's nutritional, metabolic and endocrine status, impacting athletic performance and recovery.
“These factors may negatively impact an athlete’s nutritional, metabolic and endocrine status impacting athletic performance and recovery [1], (e.g., impaired glucose metabolism could reduce glycogen repletion while impaired protein synthesis could reduce recovery and adaptation from training).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
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- Premisecitation
Lifestyle factors such as caffeine consumption, alcohol consumption and timing of sleep can cause alterations in environmental cues which may negatively impact circadian rhythms and result in negative physiological consequences.
“Lifestyle factors (e.g., caffeine consumption, alcohol consumption and timing of sleep) can cause alterations in environmental cues which may negatively impact circadian rhythms and in turn result in negative physiological consequences [26].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Golem, 2014, An integrative review of sleep for nutrition professionals, Adv. Nutr. source
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- Premisecitation
The timing and quantity of meals can affect circadian rhythms.
“as well as the timing and quantity of meals (large portions and/or meals later in the evening can negatively impact sleep potentially due to the thermogenic effect of digestion) can affect circadian rhythms [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
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- Premisecitation
Cognition, tissue repair and metabolism are critical psychological and physiological factors that contribute to training capacity, recovery and ultimately performance.
“Cognition, tissue repair and metabolism are critical psychological and physiological factors that contribute to training capacity, recovery and ultimately performance [28].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [28] Samuels, 2016, The Athlete Sleep Screening Questionnaire: A new tool for assessing and managing sleep in elite athletes, Br. J. Sports Med. source
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- Premisecitation
Short sleep duration (<7 h per night) was associated with increased IL-6 (ES: 0.29 (0.05-0.52)).
“Short sleep duration (< 7 h per night) was associated with increased IL-6 (ES: 0.29 (0.05–0.52)), while long sleep duration (> 8 h per night) was also associated with increased IL-6 (ES: 0.11 (0.02–0.20)) but also increased CRP (ES: 0.17 (0.01–0.34)) [18].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
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- Premisecitation
Inappropriate timing of lifestyle behaviours can cause disruption to the circadian rhythm, resulting in an altered physiological response such as poor sleep.
“Inappropriate timing of lifestyle behaviours can cause disruption to the circadian rhythm, resulting in an altered physiological response (e.g., poor sleep).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [26] Golem, 2014, An integrative review of sleep for nutrition professionals, Adv. Nutr. source
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- Premisecitation
If the balance between training stress and physical recovery is inadequate, performance in subsequent training sessions or competition may be adversely affected.
“If the balance between training stress and physical recovery is inadequate, performance in subsequent training sessions or competition may be adversely affected [15].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Venter, 2012, Role of sleep in performance and recovery of athletes: A review article, South Afr. J. Res. Sport Phys. Educ. Recreat.
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- Premisecitation
In the KASIP study, Swedish adolescent elite athletes (n = 340; 178 males and 162 females) sleeping >8 h were less likely to suffer an injury (OR: 0.39; 95% CI 0.17-0.96).
“The Karolinska Athlete Screening Injury Prevention (KASIP) study investigated injury occurrence in Swedish adolescent elite athletes (n = 340; 178 males and 162 females) and demonstrated that athletes sleeping >8 h were less likely to suffer an injury (OR: 0.39; 95% CI 0.17–0.96) [35].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [35] Frohm, 2016, Too little sleep and an unhealthy diet could increase the risk of sustaining a new injury in adolescent elite athletes, Scan. J. Med. Sci. Sports
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Consumption of dairy sources may increase sleep duration.
“protein (consumption of dairy sources may increase sleep duration)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [37] Jeukendrup, 2017, Periodized Nutrition for Athletes, Sports Med. source
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- Premisecitation
In a meta-analysis, sleep disturbance (poor sleep quality, insomnia) was associated with increased levels of IL-6 (ES: 0.20 (0.08-0.31)) and CRP (ES: 0.12 (0.05-0.19)).
“In a recent meta-analysis sleep disturbance (i.e., poor sleep quality, insomnia) was associated with increased levels of IL-6 (ES: 0.20 (0.08–0.31)) and CRP (ES: 0.12 (0.05–0.19)) [18].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
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- Interpretationcitation
Increased tryptophan and melatonin concentrations appear to be the property responsible for the sleep promoting effect of night time milk.
“Increased tryptophan and melatonin concentrations appear to be the property responsible for the sleep promoting effect of night time milk.”
Quote in the paperNot a substantial claim0 of 2 sources checked - Premisecitation
Dietary precursors can influence the rate of synthesis and function of neurotransmitters, e.g., serotonin synthesis is dependent on the availability of its precursor tryptophan in the brain.
“Dietary precursors can influence the rate of synthesis and function of neurotransmitters (e.g., serotonin synthesis is dependent on the availability of its precursor tryptophan in the brain) [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
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- Interpretationcitation
A low dose of melatonin similar to nocturnal physiological concentrations can elicit a sleep-inducing effect.
“The results indicate a low dose of melatonin similar to nocturnal physiological concentrations can elicit a sleep-inducing effect.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [52] Pires, 2001, Acute effects of low doses of melatonin on the sleep of young healthy subjects, J. Pineal Res. source
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- Premisecitation
A high GI meal consumed four hours before bed significantly (p = 0.009) reduced sleep onset latency (9.0 ± 6.2 min) compared to a low GI meal (17.5 ± 6.2 min) and the same meal consumed 1 hour before bed (14.6 ± 9.9 min).
“A high GI meal consumed four hours before bed, significantly (p = 0.009) reduced sleep onset latency (9.0 ± 6.2 min) compared to a low GI meal (17.5 ± 6.2 min) and the same meal consumed 1 hour before bed (14.6 ± 9.9 min) [44].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [44] Afaghi, 2007, High-glycemic-index carbohydrate meals shorten sleep onset, Am. J. Clin. Nutr. source
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- Interpretationreasoning
Nutrition interventions that act on sleep-wake neurotransmitters could positively impact sleep.
“Therefore, nutrition interventions that act on these neurotransmitters could positively impact sleep.”
Quote in the paperSubstantial claim - Premisecitation
Among a large sample (n = 4452) from the National Health and Nutrition Examination survey, lower carbohydrate intake was significantly associated (OR 0.71; 0.55-0.92, p = 0.01) with insomnia symptoms (difficulty maintaining sleep).
“Among a large sample (n = 4452) from the National Health and Nutrition Examination survey lower carbohydrate intake (24–h recall and structured interview) has been significantly associated (OR 0.71; 0.55–0.92, p = 0.01) with insomnia symptoms (difficulty maintaining sleep) [46].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [46] Grandner, 2014, Sleep symptoms associated with intake of specific dietary nutrients, J. Sleep Res. source
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- Interpretationreasoning
High glycaemic index carbohydrate increases tryptophan availability for synthesis of serotonin and ultimately melatonin.
“This increases tryptophan availability for synthesis of serotonin and ultimately melatonin.”
Quote in the paperSubstantial claim - Premisecitation
Several neurotransmitters (5-HT, GABA, orexin, melanin concentrating hormone, cholinergic, galanin, noradrenaline and histamine) are involved with the sleep-wake cycle.
“Several neurotransmitters are involved with the sleep-wake cycle including 5–hydroxytryptophan (5-HT), GABA, orexin, melanin concentrating hormone, cholinergic, galanin, noradrenaline and histamine [7].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7] Saper, 2005, Hypothalamic regulation of sleep and circadian rhythms, Nature source
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- Premisecitation
Carbohydrate consumption increases plasma tryptophan concentrations.
“Carbohydrate consumption has been shown to increase plasma tryptophan concentrations [44].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [44] Afaghi, 2007, High-glycemic-index carbohydrate meals shorten sleep onset, Am. J. Clin. Nutr. source
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- Premisecitation
Consumption of high glycaemic index carbohydrate increases the ratio of circulating tryptophan:LNAA via direct action of insulin which promotes muscle uptake of LNAA.
“Consumption of high glycaemic index (GI) carbohydrate increases the ratio of circulating tryptophann:LNAA via direct action of insulin which promotes muscle uptake of LNAA [45].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [45] Oliver, 2017, Sleep improvement in athletes: Use of nutritional supplements, Am. J. Sports Med.
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- Premisecitation
Glycaemic index affects sleep onset latency.
“GI has been shown to affect sleep onset latency (length of time of the transition from wake to sleep) [44].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [44] Afaghi, 2007, High-glycemic-index carbohydrate meals shorten sleep onset, Am. J. Clin. Nutr. source
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- Premisecitation
When night time milk was supplemented with tryptophan (2.5 g/L), circulating melatonin concentrations significantly increased further (35.5%).
“When the night time milk was supplemented with tryptophan (2.5 g/L) circulating melatonin concentrations significantly increased further (35.5%) [51].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [51] Milagres, 2014, Night milking adds value to cow’s milk, J. Sci. Food Agric. source
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- Premisecitation
Consumption of night time milk (melatonin concentration of 39.43 pg/mL) compared to daytime milk (4.03 pg/mL) significantly increased circulating melatonin (26.5%) in rats.
“Consumption of night time milk (melatonin concentration of 39.43 pg/mL) compared to daytime milk (4.03 pg/mL) significantly increased circulating melatonin (26.5%) concentration in rats [51], indicating that high melatonin concentrations are necessary for milk to affect blood melatonin concentrations.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [51] Milagres, 2014, Night milking adds value to cow’s milk, J. Sci. Food Agric. source
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- Premisecitation
Tryptophan is transported across the blood brain barrier by a system that shares transporters with several large neutral amino acids (LNAA).
“Tryptophan is transported across the blood brain barrier by a system that shares transporters with several large neutral amino acids (LNAA) [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
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- Premisecitation
Dietary tryptophan has been shown to improve sleep.
“Dietary tryptophan has been shown to improve sleep, in a comparison of food bars (Food 1: 25 g deoiled butternut squash seed meal and 25 g dextrose, Food 2: 250 mg of pharmaceutical tryptophan and Food 3: 50 g rolled oats [control]) [53].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [53] Hudson, 2005, Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia, Nutr. Neurosci. source
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- Premisecitation
There appears to be no added benefit to melatonin doses >3 mg.
“however, it must be noted that there appears to be no added benefit to doses >3 mg [49].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [49] Collin, 2010, Melatonin: Action as antioxidant and potential applications in human disease and aging, Toxicology source
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- Interpretationcitation
High melatonin concentrations are necessary for milk to affect blood melatonin concentrations.
“indicating that high melatonin concentrations are necessary for milk to affect blood melatonin concentrations.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [51] Milagres, 2014, Night milking adds value to cow’s milk, J. Sci. Food Agric. source
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- Premisecitation
A positive effect of low doses (0.3 mg or 1 mg) of exogenous melatonin on sleep onset latency was observed in a small group of healthy males (n = 6) when administered at 6:00 pm and 8:00 pm.
“A positive effect of low doses (0.3 mg or 1 mg) of exogenous melatonin (gelatin capsules) on sleep onset latency has been observed in a small group of healthy males (n = 6), when administered at either 6:00 pm (0.3 mg 16.5 ± 19.9 min; 1 mg 12.3 ± 13.6 min; Placebo 23.1 ± 22.7 min) and 8:00 pm (0.3 mg 19.6 ± 14.1 min; 1 mg 20.7 ± 17.7 min; Placebo 53.4 ± 51.9 min) [52].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [52] Pires, 2001, Acute effects of low doses of melatonin on the sleep of young healthy subjects, J. Pineal Res. source
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- Premisecitation
Melatonin increases the protective effects of glutathione, vitamin C, and trolox through regeneration by electron transfer processes.
“Melatonin also increases the protective effects of glutathione, vitamin C and trolox, through regeneration by electron transfer processes [69].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [69] Galano, A., Castañeda-Arriaga, R., Pérez-González, A., Tan, D.X., and Reiter, R. (2016). Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress. Molecules, 21. source
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- Premisecitation
Tart cherry juice supplementation post exercise may aid recovery from running a marathon.
“Indeed, there is evidence that tart cherry juice supplementation post exercise may aid recovery from running a marathon [67].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
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- Premisecitation
Kiwifruit are nutritionally dense, containing a range of nutrients that can benefit sleep, health, and recovery.
“Kiwifruit are nutritionally dense containing a range of nutrients that can benefit sleep, health and recovery including serotonin, vitamin C, vitamin E, vitamin K, folate, anthocyanidins, carotenoids, beta-carotene, lutein, potassium, copper and fibre [70].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
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- Premisecitation
Self-report measures of wake after sleep onset, sleep onset latency, and sleep efficiency improved significantly following the four-week kiwifruit intervention (p ≤ 0.002).
“Self-report measures also improved significantly, wake after sleep onset reduced (time awake during sleep period) (–28.9%), sleep onset latency reduced (–35.4%) while sleep efficiency increased (5.4%) (p ≤ 0.002) [70].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
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- Premisecitation
Ingestion of α-lactalbumin enriched whey protein significantly (p < 0.05) increased tryptophan:LNAA by 48% compared to a casein enriched diet.
“Ingestion of α-lactalbumin enriched whey protein, significantly (p < 0.05) increased tryptophan:LNAA by 48% compared to a casein enriched diet [54].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [54] Markus, 2000, The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress, Am. J. Clin. Nutr. source
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- Premisecitation
Tryptophan depletion studies have demonstrated decreased tryptophan plasma concentrations affected sleep fragmentation (arousal index), REM sleep latency, and REM density compared to baseline and placebo.
“Tryptophan depletion studies have demonstrated decreased tryptophan plasma concentrations affected sleep fragmentation (arousal index (events/h)), REM sleep latency (the interval between first epoch of stage 2 and the first epoch of REM sleep), and REM density (the cumulated duration of each REM burst divided by the duration of each REM sleep period) compared to baseline and placebo [56,57].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [56] Arnulf, 2002, Mid-morning tryptophan depletion delays REM sleep onset in healthy subjects, Neuropsychopharmacology source
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- cites [57] Bhatti, 1998, Effects of a tryptophan-free amino acid drink challenge on normal human sleep electroencephalogram and mood, Biol. Psychiatry source
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- Premisecitation
Tart cherry juice consumption significantly reduced insomnia severity index scores and wake after sleep onset time in older females with insomnia (n = 7) compared to placebo.
“A similar study demonstrated that tart cherry juice consumption resulted in significantly reduced insomnia severity index scores (13.2 ± 2.8 versus control 14.9 ± 3.6; p < 0.05) and wake after sleep onset time (62.1 ± 37.4 min versus control, 79.1 ± 38.6 mins; p < 0.01), in older females with insomnia (n = 7) compared to a placebo [68].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [68] Pigeon, 2010, Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: A pilot study, J. Med. Food source
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- Premisecitation
The intervention group demonstrated a more rapid return of baseline isometric knee extension strength at 48 h post-marathon compared to the control group.
“The intervention group demonstrated a more rapid return of baseline isometric knee extension strength (pre-race 432 ± 114 vs. 48h 435 ± 109), 48 h post-marathon which was not demonstrated in the control group (pre-race 384 ± 112 vs. 48 h 349 ± 96) [67]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
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- Premisecitation
The milk protein α-lactalbumin has the highest natural levels of tryptophan among all protein food sources.
“The milk protein, α-lactalbumin has been reported as having the highest natural levels of tryptophan among all protein food sources [54].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [54] Markus, 2000, The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress, Am. J. Clin. Nutr. source
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- Premisecitation
Repeated exercise bouts (training) induce disruption in skeletal muscle homeostasis that regulate training adaptations.
“It is accepted that repeated exercise bouts (i.e. training) induce disruption in skeletal muscle homeostasis that regulate training adaptations [62,63].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [62] Cobley, 2015, The basic chemistry of exercise induced DNA oxidation: Oxidative damage, redox signalling, and their interplay, Front. Physiol. source
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- cites [63] Cobley, 2015, Influence of Vitamin C and Vitamin E on redox signalling: Impications for exercise adaptations, Free Radic. Biol. Med. source
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- Premisecitation
Sleep quality was significantly improved following the four-week kiwifruit intervention.
“Sleep quality was significantly improved following the four-week kiwifruit intervention however, the lack of a control group must be noted and there was a high level of subject drop out (n = 5).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
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- Premisecitation
Regular consumption of kiwifruit significantly increases plasma vitamin C, vitamin E, and lutein/zeaxanthin concentrations.
“Regular consumption of kiwifruit has been found to significantly (p ≤ 0.05) increase plasma vitamin C [74] vitamin E [71] and lutein/zeaxanthin concentrations [71,74].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [74] Beck, 2011, Gold kiwifruit consumed with an iron-fortified breakfast cereal meal improves iron status in women with low iron stores: A 16-week randomised controlled trial, Br. J. Nutr. source
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- cites [71] Hunter, 2012, Consumption of gold kiwifruit reduces severity and duration of selected upper respiratory tract infection symptoms and increases plasma vitamin C concentration in healthy older adults, Br. J. Nutr. source
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- Premisecitation
Post-race elevations in CRP and uric acid were significantly reduced in the intervention group (p < 0.001).
“Similarly, post-race elevations in CRP and uric acid were significantly reduced in the intervention group (p < 0.001) [67].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
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- Interpretationcitation
Consumption of tryptophan rich protein (e.g., milk) could affect changes in core temperature improving sleep quality.
“Consumption of tryptophan rich protein (e.g., milk) could affect changes in core temperature improving sleep quality [51].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [51] Milagres, 2014, Night milking adds value to cow’s milk, J. Sci. Food Agric. source
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- Premisecitation
Consumption of two kiwifruit one hour before bedtime for four weeks significantly improved actigraphy-measured total sleep duration and sleep efficiency in volunteers (n = 25) with self-reported sleep disturbance.
“A study involving volunteers (n = 25) with a self-reported sleep disturbance demonstrated consumption of two kiwifruit one hour before bedtime for four weeks significantly improved actigraphy-measured total sleep duration (+16.9%, baseline 354.5 ± 17.1 min; post-intervention 395.3 ± 17.4 min) and sleep efficiency (+2.4%, baseline 93.9 ± 1.03 min; post-intervention 95.9 ± 0.67 min) (p ≤ 0.005) [70]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
Not checked in the free run.
- Interpretationcitation
Relatively small doses (250 mg) of dietary tryptophan can positively impact sleep.
“indicating that relatively small doses (250 mg) of dietary tryptophan can positively impact sleep.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [53] Hudson, 2005, Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia, Nutr. Neurosci. source
Not checked in the free run.
- Interpretationcitation
Consumption of tart cherry juice may blunt the secondary muscle damage response (localised inflammation).
“indicating that consumption of tart cherry juice may blunt the secondary muscle damage response (localised inflammation).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
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- Premisecitation
Post-race levels of inflammation (IL-6) were significantly reduced in the intervention group compared to the control group.
“Post-race levels of inflammation were significantly reduced in the intervention group (IL-6 41.8 pg/mL) compared to the control group (IL-6 82.1 pg/mL) [67].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
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- Premisecitation
Dietary antioxidants (e.g., vitamin C and vitamin E) augment endogenous antioxidant content within skeletal muscle.
“Dietary antioxidants (e.g., vitamin C and vitamin E) augment endogenous antioxidant content within skeletal muscle [59].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [59] Nieman, D.C., and Mitmesser, S.H. (2017). Potential Impact of Nutrition on Immune System Recovery from Heavy Exertion: A Metabolomics Perspective. Nutrients, 9. source
Not checked in the free run.
- Interpretationcitation
Nutrients such as antioxidants, tryptophan-rich protein, carbohydrate, melatonin, micronutrients, and fruit can affect sleep.
“Nutrients such as antioxidants, tryptophan rich protein, carbohydrate, melatonin, micronutrients and fruit can affect sleep [37,39,40].”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [37] Jeukendrup, 2017, Periodized Nutrition for Athletes, Sports Med. source
Not checked in the free run.
- cites [39] Tahara, 2014, Chrono-biology, Chrono-pharmacology and Chrono-nutrition, J. Pharmacol. Sci. source
Not checked in the free run.
- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
- Premisecitation
Folate and pyridoxine are involved in the conversion of tryptophan into serotonin.
“Folate (vitamin B9) and pyridoxine are involved in the conversion of tryptophan into serotonin [45].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [45] Oliver, 2017, Sleep improvement in athletes: Use of nutritional supplements, Am. J. Sports Med.
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- Premisecitation
A food-based supplement containing 5 mg melatonin, 225 mg magnesium, and 11.25 mg zinc significantly improved subjective sleep quality scores and total sleep duration in older adults (n = 43).
“A placebo controlled double blind study on older adults (n = 43), demonstrated a food based supplement containing 5 mg melatonin, 225 mg magnesium and 11.25 mg zinc, significantly (p < 0.001) improved subjective sleep quality scores in the intervention group but not the controls (difference between the groups 6.8; 95% CI 5.4–8.3) and total sleep duration (182.18 min; 95% CI 160.02–204.34) assessed”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [75] Rondanelli, 2011, The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: A double-blind, placebo-controlled clinical trial, J. Am. Geriatr. Soc. source
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- Study design and conductreasoning
The findings of the kiwifruit sleep study may be prone to bias as subjects were recruited based on interest in participation in a dietary intervention study relating to sleep.
“The findings may be prone to bias as subjects were recruited based on interest in participation in a dietary intervention study relating to sleep.”
Quote in the paperNot a substantial claim - Premisecitation
Magnesium is important for the production of the enzyme N-acetyltransferase, which converts 5-HT into N-acetyl-5-hydroxytryptamine, which can then be converted to melatonin.
“Magnesium is important for the production of the enzyme N-acetyltransferase which converts 5-HT into N-acetyl-5-hydroxytryptamine, which can then be converted to melatonin [44].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [44] Afaghi, 2007, High-glycemic-index carbohydrate meals shorten sleep onset, Am. J. Clin. Nutr. source
Not checked in the free run.
- May combine two claims. 59
- Classified as probably not a substantial claim. 10
May combine two claims.
PremisecitationSleep disturbances and short sleep duration are behavioural risk factors for inflammation and are associated with increased risk of illness and disease.
“Sleep disturbances and short sleep duration are behavioural risk factors for inflammation, associated with increased risk of illness and disease, which can be modified to promote sleep health.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
- cites [42] Hirshkowitz, 2015, National Sleep Foundation’s sleep time duration recommendations: Methodology and results summary, Sleep Health source
Not checked in the free run.
May combine two claims.
PremisecitationSleep has a restorative effect on the immune system, the endocrine system, facilitates recovery of the nervous system and metabolic cost of the waking state, and has an integral role in learning, memory and synaptic plasticity.
“Sleep has been shown to have a restorative effect on the immune system, the endocrine system, facilitate the recovery of the nervous system and metabolic cost of the waking state and has an integral role in learning, memory and synaptic plasticity, all of which can impact both athletic recovery and performance.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
- cites [19] Frank, 2006, The mystery of sleep function: Current perspectives and future directions, Rev. Neurosci. source
Not checked in the free run.
May combine two claims.
InterpretationreasoningCaffeine consumption can lead to poor sleep which, in turn, can lead to increased caffeine consumption.
“Caffeine consumption can lead to poor sleep which, in turn, can lead to increased caffeine consumption.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
PremisecitationNutrition support needs to be periodised in relation to the demands of the athlete's daily training and overall nutritional goals.
“Nutrition support needs to be periodised in relation to the demands of the athlete’s daily training and overall nutritional goals [36].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [36] Thomas, 2016, American College of Sports Medicine Joint Position Statement. Nutrition and Athletic Performance, Med. Sci. Sports Exerc.
Not checked in the free run.
May combine two claims.
PremisecitationSleep deprivation adversely affects glucose metabolism and neuroendocrine function, which can affect carbohydrate metabolism, appetite, energy intake and protein synthesis.
“Sleep deprivation adversely affects glucose metabolism and neuroendocrine function which can affect carbohydrate metabolism, appetite, energy intake and protein synthesis [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
Not checked in the free run.
May combine two claims.
PremisecitationTraining adaptations and recovery can be maximised by optimal nutrition practices or impaired by suboptimal nutrition practices.
“Training adaptations and recovery can be maximised by optimal nutrition practices or impaired by suboptimal nutrition practices [36,37,38].”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [36] Thomas, 2016, American College of Sports Medicine Joint Position Statement. Nutrition and Athletic Performance, Med. Sci. Sports Exerc.
Not checked in the free run.
- cites [37] Jeukendrup, 2017, Periodized Nutrition for Athletes, Sports Med. source
Not checked in the free run.
- cites [38] Close, 2016, New strategies in sport nutrition to increase exercise performance, Free Radic. Biol. Med. source
Not checked in the free run.
May combine two claims.
PremisecitationLong sleep duration (>8 h per night) was associated with increased IL-6 (ES: 0.11 (0.02-0.20)) and increased CRP (ES: 0.17 (0.01-0.34)).
“Short sleep duration (< 7 h per night) was associated with increased IL-6 (ES: 0.29 (0.05–0.52)), while long sleep duration (> 8 h per night) was also associated with increased IL-6 (ES: 0.11 (0.02–0.20)) but also increased CRP (ES: 0.17 (0.01–0.34)) [18].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
May combine two claims.
PremisecitationSleep has a pivotal role in performance, training adaptations and recovery.
“Sleep also has a pivotal role to play in performance, training adaptations and recovery [1,18].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
Not checked in the free run.
- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
May combine two claims.
PremisecitationSleep disturbance and extremes of sleep duration affect risk factors of inflammatory disease and contribute to all-cause mortality.
“Research has demonstrated that sleep disturbance (i.e. insomnia) and extremes of sleep durations affect risk factors of inflammatory disease and contribute to all-cause mortality [18,22].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
- cites [22] Vgontzas, 2013, Insomnia with objective short sleep duration: The most biologically severe phenotype of the disorder, Sleep Med. Rev. source
Not checked in the free run.
May combine two claims.
PremisecitationCaffeine increases sleep onset latency, reduces total sleep duration and reduces sleep quality.
“caffeine (increased sleep onset latency, reduced total sleep duration and reduced sleep quality) [39]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [39] Tahara, 2014, Chrono-biology, Chrono-pharmacology and Chrono-nutrition, J. Pharmacol. Sci. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe classic view of sleep is that it is a recovery process, with the circadian system regulating feelings of sleepiness and wakefulness throughout the day.
“The classic view of sleep is that it is a recovery process, with the circadian system regulating feelings of sleepiness and wakefulness throughout the day [28].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [28] Samuels, 2016, The Athlete Sleep Screening Questionnaire: A new tool for assessing and managing sleep in elite athletes, Br. J. Sports Med. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe focus of 'training' nutrition is to promote adaptations while the focus of 'competition' nutrition is optimal performance.
“The focus of ‘training’ nutrition is to promote adaptations while the focus of ‘competition’ nutrition is optimal performance [36].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [36] Thomas, 2016, American College of Sports Medicine Joint Position Statement. Nutrition and Athletic Performance, Med. Sci. Sports Exerc.
Not checked in the free run.
May combine two claims.
PremisecitationSleep disturbances and inadequate sleep duration have been reported in athletic populations.
“Sleep disturbances and inadequate sleep duration have been reported in athletic populations.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [32] Tuomilehto, 2017, Sleep of professional athletes: Underexploited potential to improve health and performance, J. Sports Sci. source
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- cites [33] Erlacher, 2011, Sleep habits in German athletes before important competitions or games, J. Sports Sci. source
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- cites [15] Venter, 2012, Role of sleep in performance and recovery of athletes: A review article, South Afr. J. Res. Sport Phys. Educ. Recreat.
Not checked in the free run.
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PremisecitationA meta-analysis of sleep duration and all-cause mortality demonstrated a U-shaped association: long sleep (>8 h per night) has a 30% greater risk (RR: 1.30 (1.22-1.38)) and short sleep (<7 h per night) has a 12% greater risk (RR: 1.12 (1.06-1.18)) compared to normal sleep (7-8 h per night).
“Similarly, a meta-analysis of sleep duration and all-cause mortality demonstrated a U-shaped association, whereby long sleep (> 8 h per night) has a 30% (RR: 1.30 (1.22–1.38)) greater risk while short sleep (<7 h per night) has a 12% (RR: 1.12 (1.06–1.18)) greater risk compared to normal sleep reference (7–8 h per night) [25].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [25] Cappuccio, 2010, Sleep duration and all-cause mortality: A systematic review and meta-analysis of prospective studies, Sleep source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe relationship between sleep, performance and recovery can be viewed in terms of three key factors: sleep length, sleep quality and sleep phase.
“The relationship between sleep, performance and recovery can be viewed in terms of 3 key factors that affect the recuperative outcome: Sleep length (total sleep duration; hours/night, plus naps)Sleep quality (i.e., the experience and perceived adequacy of sleep)Sleep phase (circadian timing of sleep) [28].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [28] Samuels, 2016, The Athlete Sleep Screening Questionnaire: A new tool for assessing and managing sleep in elite athletes, Br. J. Sports Med. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisecitation66% (n = 416) of elite German athletes (n = 632) reported pre-competition insomnia symptomology including difficulty falling asleep, waking during the night and early final waking times.
“While a similar study found that 66% (n = 416) of elite German athletes (n = 632) reported pre-competition insomnia symptomology including difficulty falling asleep, waking during the night and early final waking times [33].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [33] Erlacher, 2011, Sleep habits in German athletes before important competitions or games, J. Sports Sci. source
Not checked in the free run.
May combine two claims.
PremisecitationLarge portions and/or meals later in the evening can negatively impact sleep, potentially due to the thermogenic effect of digestion.
“large portions and/or meals later in the evening can negatively impact sleep potentially due to the thermogenic effect of digestion) can affect circadian rhythms [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
May combine two claims.
PremisecitationCaffeine increases alertness by antagonising adenosine receptors, which leads to a reduction in the inclination to sleep.
“Caffeine increases the state of alertness, antagonising adenosine receptors, which also leads to a reduction in the inclination to sleep [39].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [39] Tahara, 2014, Chrono-biology, Chrono-pharmacology and Chrono-nutrition, J. Pharmacol. Sci. source
Not checked in the free run.
May combine two claims.
PremisecitationMuscle fatigue or soreness may adversely affect sleep, with inflammatory cytokines linked to disruption of normal sleep.
“Muscle fatigue or soreness may adversely affect sleep, with inflammatory cytokines linked to disruption of normal sleep [29].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [29] Hausswirth, 2014, Evidence of disturbed sleep and increased illness in overreached endurance athletes, Med. Sci. Sports Exerc. source
Not checked in the free run.
May combine two claims.
PremisecitationSleep deprivation is associated with increased catabolic and reduced anabolic hormones, which results in impaired muscle protein synthesis, blunting training adaptations and recovery.
“Sleep deprivation is associated with increased catabolic and reduced anabolic hormones which results in impaired muscle protein synthesis [31], blunting training adaptations and recovery.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [31] Dattilo, 2011, Sleep and muscle recovery: Endocrinological and molecular basis for a new and promising hypothesis, Med. Hypotheses source
Not checked in the free run.
May combine two claims.
PremisecitationAlcohol consumption is associated with poorer sleep quality and quantity, reduced REM sleep and increased sleep disturbance in the second half of the sleep bout.
“Alcohol consumption has been associated with poorer sleep quality and quantity, reduced REM sleep and increased sleep disturbance in the second half of the sleep bout [41].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [41] Roehrs, 2001, Sleep, sleepiness, and alcohol use, Alcohol. Res. Health
Not checked in the free run.
May combine two claims.
PremisecitationTryptophan is an essential amino acid that is a precursor to serotonin and melatonin, and can cross the blood-brain barrier by competing for transport with other LNAA.
“Tryptophan is an essential amino acid that is a precursor to serotonin and melatonin, which can cross the blood-brain barrier by competing for transport with other LNAA [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
Not checked in the free run.
May combine two claims.
PremisecitationInsulin influences the transport of tryptophan across the blood brain barrier after a carbohydrate rich meal and facilitates the uptake of LNAA by muscle.
“Insulin influences the transport of tryptophan across the blood brain barrier after a carbohydrate rich meal, as it is an anabolic agent it also facilitates the uptake of LNAA by muscle [26].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [26] Golem, 2014, An integrative review of sleep for nutrition professionals, Adv. Nutr. source
Not checked in the free run.
May combine two claims.
PremisecitationSleep disturbances and sleep deprivation are risk factors for inflammation, which can be treated or managed to promote recovery and/or performance.
“Similar to nutrition, sleep disturbances (difficulty initiating or maintain sleep) and sleep deprivation (not getting enough sleep) are risk factors for inflammation [18,42], which can be treated or managed to promote recovery and/or performance.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [18] Irwin, 2016, Sleep disturbance, sleep duration, and inflammation: A systematic review and meta-analysis of cohort studies and experimental sleep deprivation, Biol. Psychiatry source
Not checked in the free run.
- cites [42] Hirshkowitz, 2015, National Sleep Foundation’s sleep time duration recommendations: Methodology and results summary, Sleep Health source
Not checked in the free run.
May combine two claims.
InterpretationcitationSince endogenous melatonin influences core temperature facilitating sleep, increased exogenous melatonin could affect changes in core temperature improving sleep quality.
“Since endogenous melatonin influences core temperature facilitating sleep, increased exogenous melatonin could affect changes in core temperature improving sleep quality [50].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [50] Howatson, 2012, Effect of tart cherry juice (Prunus Cerasus) on melatonin levels and enhanced sleep quality, Eur. J. Nutr. source
Not checked in the free run.
- Rests on an assumption: The effect of exogenous melatonin on sleep quality is relative to the person’s endogenous melatonin levels.
May combine two claims.
PremisecitationFor sleep to have a restorative effect, it must be of adequate duration, which is dependent on age.
“For sleep to have a restorative effect on the body, it must be of adequate duration which is dependent on age [28,42].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [28] Samuels, 2016, The Athlete Sleep Screening Questionnaire: A new tool for assessing and managing sleep in elite athletes, Br. J. Sports Med. source
Not checked in the free run.
- cites [42] Hirshkowitz, 2015, National Sleep Foundation’s sleep time duration recommendations: Methodology and results summary, Sleep Health source
Not checked in the free run.
May combine two claims.
PremisecitationMelatonin is a naturally-occurring compound in cow's milk, but its concentration increases significantly if cows are milked in darkness at night, referred to as 'night time milk'.
“Melatonin is a naturally-occurring compound in cow’s milk, but its concentration increases significantly if cows are milked in darkness at night referred to as ‘night time milk’ [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
May combine two claims.
PremisecitationThe ratio of tryptophan:LNAA in the blood is vital to the transport of tryptophan into the brain and can be increased through consumption of tryptophan, a high carbohydrate/low protein diet or α-lactalbumin.
“The ratio of tryptophan:LNAA in the blood is vital to the transport of tryptophan into the brain and can be increased through consumption of tryptophan, a high carbohydrate/low protein diet or α-lactalbumin (whey derived protein) [43].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [43] Silber, 2010, Effects of tryptophan loading on human cognition, mood, and sleep, Neurosci. Biobehav. Rev. source
Not checked in the free run.
May combine two claims.
PremisecitationIngestion of melatonin affects sleep propensity and has hypnotic effects enhancing sleep quality and duration; pharmacological melatonin can be used to manipulate circadian timing.
“Ingestion of melatonin affects sleep propensity and has hypnotic effects enhancing sleep quality and duration, pharmacological melatonin can be used to manipulate circadian timing [49].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [49] Collin, 2010, Melatonin: Action as antioxidant and potential applications in human disease and aging, Toxicology source
Not checked in the free run.
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PremisecitationA dose response relationship for melatonin was not evident, as the 0.3 mg dose was as effective as the 1 mg dose when administered at 6:00 pm or 8:00 pm.
“A dose response relationship was not evident as the 0.3 mg dose, which is similar to endogenous melatonin concentrations, was as effective as the 1 mg dose when administered at 6:00 pm or 8:00 pm.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [52] Pires, 2001, Acute effects of low doses of melatonin on the sleep of young healthy subjects, J. Pineal Res. source
Not checked in the free run.
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PremisecitationMelatonin is a hormone secreted by the pineal gland that has sedative effects.
“Melatonin is a hormone secreted by the pineal gland, that has displayed sedative effects [48,49].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [48] Ramis, 2015, Protective effects of melatonin and mitochondria-targeted antioxidants against oxidative stress: A review, Curr. Med. Chem. source
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- cites [49] Collin, 2010, Melatonin: Action as antioxidant and potential applications in human disease and aging, Toxicology source
Not checked in the free run.
May combine two claims.
PremisecitationThe impact of melatonin on sleep onset latency was time dependent: a 0.3 mg dose increased sleep onset latency when consumed at 9:00 pm, and there was no evidence of an effect when the 1 mg dose was administered at 9:00 pm.
“However, the impact was time dependent as a 0.3 mg dose increased sleep onset latency when consumed at 9:00 pm (0.3 mg 25.1 ± 10.5 min; 1 mg 12.1 ± 7.4 min; Placebo 8.8 ± 4 min) and there was no evidence of an effect when the 1 mg dose was administered at 9:00 pm [52].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [52] Pires, 2001, Acute effects of low doses of melatonin on the sleep of young healthy subjects, J. Pineal Res. source
Not checked in the free run.
May combine two claims.
PremisecitationCarbohydrates affect plasma tryptophan:LNAA ratio and may complement the sleep enhancing effect of consuming tryptophan rich protein.
“Carbohydrates affect plasma tryptophan:LNAA ratio and may compliment the sleep enhancing effect of consuming tryptophan rich protein [40].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationSleep recommendations change over the lifespan: adolescents 8-10 h, adults 7-9 h, and older adults 7-8 h.
“Sleep recommendations particularly the amount of sleep required, change over the lifespan from adolescents (8–10 h), adults (7–9 h), and older adults (7–8 h) [42].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [42] Hirshkowitz, 2015, National Sleep Foundation’s sleep time duration recommendations: Methodology and results summary, Sleep Health source
Not checked in the free run.
Classified as probably not a substantial claim.
PremisecitationThe internal clock can be altered by changing the timing and nature of food intake.
“It has been suggested that the internal clock can be altered by changing the timing and nature of food intake [39].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [39] Tahara, 2014, Chrono-biology, Chrono-pharmacology and Chrono-nutrition, J. Pharmacol. Sci. source
Not checked in the free run.
May combine two claims.
PremisecitationConversion to serotonin is dependent on sufficient precursor availability in the brain; an increase in brain tryptophan occurs when the ratio of free tryptophan to branched chain amino acids increases; following tryptophan conversion to serotonin, melatonin is produced.
“Conversion to serotonin is dependent on sufficient precursor availability in the brain, an increase in brain tryptophan occurs when the ratio of free tryptophan to branched chain amino acids increases, following tryptophan conversion to serotonin, melatonin is produced [1].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [1] Halson, 2014, Sleep in elite athletes and nutritional interventions to enhance sleep, Sports Med. source
Not checked in the free run.
May combine two claims.
PremisecitationMelatonin has extremely low toxicity even at relatively high doses and can easily cross physiological barriers due to its optimal size, partial water solubility and high lipid solubility.
“Melatonin has extremely low toxicity even at relatively high doses and can easily cross physiological barriers due to its optimal size, partial water solubility and high lipid solubility however, it must be noted that there appears to be no added benefit to doses >3 mg [49].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [49] Collin, 2010, Melatonin: Action as antioxidant and potential applications in human disease and aging, Toxicology source
Not checked in the free run.
May combine two claims.
PremisecitationSupplementation with high doses (800 IU/day) of vitamin E did not counteract oxidative stress in triathletes (n = 38); the intervention group demonstrated significantly (p ≤ 0.05) higher levels of post-race inflammation and oxidative stress (Plasma F2-isoprostanes increased 181% versus 97% and IL-6 166 ± 28 pg∙mL-1 versus 88 ± 13 pg∙mL-1) than the control group.
“However, supplementation with high doses (800 IU/day) of vitamin E did not counteract OS in triathletes (n = 38), the intervention group demonstrated significantly (p ≤ 0.05) higher levels of post-race inflammation and OS (Plasma F2-isoprostanes increased 181% versus 97% and IL-6 166 ± 28 pg∙mL–1 versus 88 ± 13 pg∙mL–1) than the control group [60].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [60] Nieman, 2004, Vitamin E and immunity after the Kona triathlon world championship, Med. Sci. Sports Exerc. source
Not checked in the free run.
May combine two claims.
PremisecitationDuring recovery, athletes can suffer from delayed onset muscle soreness (DOMS), which can reduce sleep quantity and quality.
“During recovery athletes can suffer from delayed onset muscle soreness (DOMS) [66], which can reduce sleep quantity and quality.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [66] Bell, P., Stevenson, E., Davison, G., and Howatson, G. (2016). The effects of Montmorency tart cherry concentrate supplementation on recovery following prolonged, intermittent exercise. Nutrients, 8. source
Not checked in the free run.
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PremisecitationTart cherries contain high concentrations of melatonin and a range of phenolic compounds with antioxidant and anti-inflammatory properties.
“Tart cherries contain high concentrations of melatonin and a range of phenolic compounds that have both antioxidant and anti-inflammatory properties [66,67].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [66] Bell, P., Stevenson, E., Davison, G., and Howatson, G. (2016). The effects of Montmorency tart cherry concentrate supplementation on recovery following prolonged, intermittent exercise. Nutrients, 8. source
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- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationVitamin E is an important antioxidant due to its abundance within cells, mitochondrial membranes and its ability to act directly on reactive oxygen species.
“Vitamin E is an important antioxidant due to its abundance within cells, mitochondrial membranes and its ability to act directly on reactive oxygen species [60].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [60] Nieman, 2004, Vitamin E and immunity after the Kona triathlon world championship, Med. Sci. Sports Exerc. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationVitamin E reacts with other antioxidants such as vitamin C, beta-carotene and lipoic acid, which have the capacity to regenerate vitamin E from its oxidised form.
“Vitamin E reacts with other antioxidants such as vitamin C, beta-carotene and lipoic acid, which have the capacity to regenerate vitamin E from its oxidised form.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [60] Nieman, 2004, Vitamin E and immunity after the Kona triathlon world championship, Med. Sci. Sports Exerc. source
Not checked in the free run.
May combine two claims.
PremisecitationIn the intervention group, tart cherry juice supplementation significantly elevated total melatonin content, increased time in bed (+24 min), increased total sleep duration (+34 min), improved sleep efficiency (82.3%), and reduced daytime napping (-22%) (p < 0.05).
“In the intervention group tart cherry juice supplementation resulted in significantly elevated total melatonin content, increased time in bed (+24 min), increased total sleep duration (+34 min) improved sleep efficiency total (82.3%) and a significant reduction in daytime napping (–22%) (p < 0.05) [50].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [50] Howatson, 2012, Effect of tart cherry juice (Prunus Cerasus) on melatonin levels and enhanced sleep quality, Eur. J. Nutr. source
Not checked in the free run.
May combine two claims.
PremisecitationConsumption of an antioxidant does not guarantee that the compound will act as an antioxidant within the body, so positive findings from one antioxidant or combination of antioxidants cannot be generalised.
“Consumption of an antioxidant does not guarantee that the compound will act as an antioxidant within the body, therefore positive findings from one antioxidant or combination of antioxidants cannot be generalised [59].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [59] Nieman, D.C., and Mitmesser, S.H. (2017). Potential Impact of Nutrition on Immune System Recovery from Heavy Exertion: A Metabolomics Perspective. Nutrients, 9. source
Not checked in the free run.
May combine two claims.
PremisecitationTotal antioxidant capacity was increased in both groups post-race and remained elevated at 24 h in the intervention group but not the control group.
“Total antioxidant capacity was increased in both groups post-race (intervention 124% of baseline and control 112% of baseline, p < 0.01) and remained elevated at 24 h in the intervention group (114% of baseline) but not the control group [67].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [67] Howatson, 2010, Influence of tart cherry juice on indices of recovery following marathon running, Scan. J. Med. Sci. Sports source
Not checked in the free run.
May combine two claims.
InterpretationcitationElevated melatonin concentrations may not be the only mechanism by which tart cherry juice improves sleep, as sleep regulation is also influenced by proinflammatory cytokines.
“It must be noted that elevated melatonin concentrations may not be only mechanism at work as sleep regulation is also influenced by proinflammatory cytokines [3].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [3] Irwin, 2017, Sleep health: Reciprocal regulation of sleep and innate immunity, Neuropsychopharmacology source
Not checked in the free run.
May combine two claims.
PremisecitationIn a comparison of food bars, Food 1 (25 g deoiled butternut squash seed meal and 25 g dextrose) and Food 2 (250 mg pharmaceutical tryptophan) produced significant results (p ≤ 0.05) for reduction of time awake during the night (19.2% and 22.1%), increased sleep efficiency (5.19% and 7.36%) and increased subjective sleep quality (12.2% and 11.8%).
“Food 1 and Food 2 produced significant results (p ≤ 0.05) for reduction of time awake during the night (19.2% and 22.1%), increased sleep efficiency (% of time spent in bed; asleep) (5.19% and 7.36%) and increased subjective sleep quality (12.2% and 11.8%) [53], indicating that relatively small doses (250 mg) of dietary tryptophan can positively impact sleep.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [53] Hudson, 2005, Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia, Nutr. Neurosci. source
Not checked in the free run.
May combine two claims.
PremisecitationDespite increased markers of oxidative stress and inflammation in the vitamin E intervention group, there was no significant difference between the groups in terms of race performance.
“Interestingly, despite increased markers of OS and inflammation in the intervention group, there was no significant difference between the groups in terms of race performance.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [60] Nieman, 2004, Vitamin E and immunity after the Kona triathlon world championship, Med. Sci. Sports Exerc. source
Not checked in the free run.
May combine two claims.
InterpretationcitationThe range of phenolic compounds in cherries, which have anti-inflammatory and antioxidant properties, may enhance post-exercise recovery as well as sleep.
“The range of phenolic compounds in cherries which have anti-inflammatory and antioxidant properties may enhance post exercise recovery as well as sleep [50].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [50] Howatson, 2012, Effect of tart cherry juice (Prunus Cerasus) on melatonin levels and enhanced sleep quality, Eur. J. Nutr. source
Not checked in the free run.
May combine two claims.
PremisecitationAntioxidants are heterogeneous, function in a distinct manner, and do not solely regulate ROS.
“It must be noted that antioxidants are heterogeneous, they function in a distinct manner and do not solely regulate ROS [61].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [61] Finaud, 2006, Oxidative stress, Sports Med. source
Not checked in the free run.
May combine two claims.
PremisecitationAntioxidants reduce oxidative stress, play a key role in immunity, and may improve recovery following exercise.
“Antioxidants reduce OS, play a key role in immunity and may improve recovery following exercise [58,59].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [58] Halliwell, B., and Gutteridge, J.M. (2015). Free Radicals in Biology and Medicine, Oxford University Press. source
Not checked in the free run.
- cites [59] Nieman, D.C., and Mitmesser, S.H. (2017). Potential Impact of Nutrition on Immune System Recovery from Heavy Exertion: A Metabolomics Perspective. Nutrients, 9. source
Not checked in the free run.
May combine two claims.
PremisecitationTart cherry juice supplementation increased circulating melatonin levels and improved sleep time and quality in healthy adults.
“This was the first investigation to demonstrate that tart cherry juice supplementation increased circulating melatonin levels and improved sleep time and quality in healthy adults.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [50] Howatson, 2012, Effect of tart cherry juice (Prunus Cerasus) on melatonin levels and enhanced sleep quality, Eur. J. Nutr. source
Not checked in the free run.
May combine two claims.
PremisecitationIn healthy adults (n = 14) with sleep complaints, evening ingestion of α-lactalbumin (20 g) resulted in a 130% increase in tryptophan:LNAA prior to bed and a modest but significant reduction in morning sleepiness and improved alertness the following morning.
“In a similar study, healthy adults (n = 14) with sleep complaints consumed milkshakes containing either α-lactalbumin (20 g) or a casein placebo. Evening ingestion of α-lactalbumin resulted in a 130% increase in tryptophan:LNAA prior to bed and modest but significant reduction in morning sleepiness and improved alertness the following morning [55].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [55] Markus, 2005, Evening intake of α-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention, Am. J. Clin. Nutr. source
Not checked in the free run.
May combine two claims.
PremisecitationAntioxidant consumption may influence recovery from exercise but may also influence sleep since sleep regulation is influenced by pro-inflammatory cytokines.
“Antioxidant consumption may influence recovery from exercise but may also influence sleep since sleep regulation is influenced by pro-inflammatory cytokines [59].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [59] Nieman, D.C., and Mitmesser, S.H. (2017). Potential Impact of Nutrition on Immune System Recovery from Heavy Exertion: A Metabolomics Perspective. Nutrients, 9. source
Not checked in the free run.
- Rests on an assumption: Both the general population and athletes can benefit from nutritional and supplementation support to boost immunity and reduce acute and chronic inflammation during periods of increased training load and competition.
May combine two claims.
PremisecitationNiacin can be synthesised endogenously from tryptophan via the Kynurenine Pathway, therefore consuming sufficient niacin is necessary to inhibit 2,3-dioxygenase activity, eliciting a tryptophan sparing effect and increasing tryptophan availability for serotonin and melatonin synthesis.
“Niacin can be synthesised endogenously from tryptophan via the Kynurenine Pathway, therefore, consuming a sufficient amount of niacin is necessary to inhibit 2,3-dioxygenase activity eliciting a tryptophan sparing effect, increasing its availability for synthesis serotonin and melatonin [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
May combine two claims.
PremisecitationVitamin B12 contributes to melatonin secretion, pyridoxine is involved in the synthesis of serotonin from tryptophan, and niacin may elicit a tryptophan sparing effect.
“Vitamin B12 contributes to melatonin secretion, pyridoxine (vitamin B6) is involved in the synthesis of serotonin from tryptophan and niacin (vitamin B3) may elicit a tryptophan sparing effect [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPyridoxine's role in the conversion of tryptophan into serotonin is related to the amino acid decarboxylase, which speeds up the conversion rate of 5-HT to serotonin.
“Pyridoxine’s role in the conversion of tryptophan into serotonin is related to the amino acid decarboxylase which speeds up the conversion rate of 5-HT to serotonin [45].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [45] Oliver, 2017, Sleep improvement in athletes: Use of nutritional supplements, Am. J. Sports Med.
Not checked in the free run.
May combine two claims.
PremisecitationThe reduced form of folate increases tetrahydrobiopterin, a co-enzyme of tryptophan-5-hydroxylase, which converts tryptophan into 5-HT.
“The reduced form of folate (5-methyltetratrahydrofolate) increases tetrahydrobiopterin is a co-enzyme of tryptophan-5-hydroxylase which converts tryptophan into 5-hydroxytryptamine (5-HT) [45].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [45] Oliver, 2017, Sleep improvement in athletes: Use of nutritional supplements, Am. J. Sports Med.
Not checked in the free run.
May combine two claims.
PremisecitationMagnesium is believed to enhance melatonin secretion, promoting sleep onset, and act as a GABA agonist.
“Magnesium is also believed to enhance melatonin secretion promoting sleep onset and act as a GABA agonist, the main inhibitory neurotransmitter that acts on the CNS [40].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
May combine two claims.
Study design and conductcitationThe kiwifruit sleep study lacked a control group and had a high level of subject drop out (n = 5).
“the lack of a control group must be noted and there was a high level of subject drop out (n = 5).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
Not checked in the free run.
May combine two claims.
InterpretationcitationThe high folate content in kiwifruit may improve folate status and consequently improve sleep.
“the high folate content in kiwifruit may improve folate status and consequently improve sleep [70].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
Not checked in the free run.
- Rests on an assumption: Folates are destroyed by cooking or processing, but kiwifruit are typically consumed in their raw form.
May combine two claims.
PremisecitationMixed effects have been observed with different doses of cobalamin (vitamin B12) on sleep-wake rhythms and delayed sleep phase syndrome, while no effect was observed for sleep duration.
“Mixed effects have been observed, with different doses of cobalamin (vitamin B12) on sleep-wake rhythms and delayed sleep phase syndrome (a significant delay in circadian rhythm), while no effect was observed for sleep duration [41].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [41] Roehrs, 2001, Sleep, sleepiness, and alcohol use, Alcohol. Res. Health
Not checked in the free run.
May combine two claims.
PremisecitationSerotonin is the end product of L-tryptophan metabolism and is related to REM sleep.
“Serotonin is the end product of L-tryptophan metabolism and is related to REM [70].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
Not checked in the free run.
May combine two claims.
PremisecitationFolate deficiency has been linked to insomnia and restless leg syndrome.
“Folate deficiency has been linked to insomnia (difficulty initiating or maintaining sleep, extended periods of wakefulness and/or insufficient sleep) and restless leg syndrome (repeated movement of or undesirable sensations in legs leading to sleep disruption) [70]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [70] Lin, 2011, Effect of kiwifruit consumption on sleep quality in adults with sleep problems, Asia Pac. J. Clin. Nutr.
Not checked in the free run.
May combine two claims.
InterpretationreasoningThe serotonin content in kiwifruit may contribute to improved sleep, while the rich antioxidant content may suppress free radical expression and inflammatory cytokines.
“The serotonin content in kiwifruit may contribute to improved sleep while the rich antioxidant content may supress free radical expression and inflammatory cytokines.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationcitationSleep can be promoted either by inhibiting wake-promoting mechanisms or by increasing sleep-promoting factors through nutritional interventions.
“Sleep can be promoted either by inhibiting wake-promoting mechanisms or by increasing sleep promoting factors through nutritional interventions [40].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [40] Peukhuri, 2012, Diet promotes sleep duration and quality, Nutr. Res. source
Not checked in the free run.
The paper relies on this without support.
Athletes’ physical and mental recovery needs may be greater due to the high physiological and psychological demands placed on them during training and competition.
“particularly for athletes whose physical and mental recovery needs may be greater due to the high physiological and psychological demands placed on them during training and competition.”
The paper relies on this without support.
Sleep disturbances and short sleep duration can be modified to promote sleep health.
“Sleep disturbances and short sleep duration are behavioural risk factors for inflammation, associated with increased risk of illness and disease, which can be modified to promote sleep health.”
The paper relies on this without support.
The effect of exogenous melatonin on sleep quality is relative to the person’s endogenous melatonin levels.
“However, the effect is relative to the person’s endogenous melatonin levels.”
The paper relies on this without support.
Both the general population and athletes can benefit from nutritional and supplementation support to boost immunity and reduce acute and chronic inflammation during periods of increased training load and competition.
“Both the general population and athletes can benefit from nutritional and supplementation support to boost immunity and reduce acute and chronic inflammation during periods of increased training load and competition.”
The paper relies on this without support.
Supplementing magnesium, zinc, and melatonin will most likely only have an effect in cases of deficiency or insufficiency.
“It must be noted that supplementing these nutrients will most likely only have an effect in cases of deficiency or insufficiency.”
The paper relies on this without support.
Folates are destroyed by cooking or processing, but kiwifruit are typically consumed in their raw form.
“Although folates are widely consumed in the diet, they are destroyed by cooking or processing, however, kiwifruit are typically consumed in their raw form.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several nutrients-carbohydrates (high-glycemic index dinners), melatonin, tryptophan-rich protein, antioxidant-rich fruits (e.g., tart cherry juice and kiwi), and micronutrients-have been shown to improve sleep.
“considering that several nutrients have been shown to improve sleep such as carbohydrates (high-glycemic index dinners), melatonin, tryptophan-rich protein, antioxidant-rich fruits (e.g., tart cherry juice and kiwi), and micronutrients [147].”
From The 4R’s Framework of Nutritional Strategies for Post-Exercise Recovery: A Review with Emphasis on New Generation of Carbohydrates (2020) · cites this paper as [147]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Sleep efficiency is reported in minutes despite being defined as a percentage
MinorThe paper defines sleep efficiency as a percentage of time in bed spent asleep, but gives the kiwifruit study's baseline and post-intervention sleep-efficiency values in minutes.
“sleep efficiency (+2.4%, baseline 93.9 ± 1.03 min; post-intervention 95.9 ± 0.67 min)”
“increased sleep efficiency (% of time spent in bed; asleep) (5.19% and 7.36%)”
Arousal-system activation is said to facilitate sleep
MinorThe account says that arousal-system activation inhibits sleep-active neurons yet facilitates sleep. Elsewhere, it describes activation of sleep-promoting neurons as reinforcing sleep episodes.
“Activation of arousal systems inhibits sleep active neurons facilitating sleep”
“activation of sleep-promoting neurons inhibits arousal-related neurons reinforcing consolidated sleep episodes”
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New strategies in sport nutrition to increase exercise performance
Close, G. L., Hamilton, D. L., Philp, A., Burke, L. M., & Morton, J. P. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.01.016 · Cited by 221 · cited 1× · see citing works
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“Sleep phase (circadian timing of sleep) [28].”
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Heart rate variability during night sleep and after awakening in overtrained athletes
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BackgroundEffects of a tart cherry juice beverage on the sleep of older adults with insomnia: A pilot study
Pigeon, W. R., Carr, M., Gorman, C., & Perlis, M. L. (2010) · Journal of Medicinal Food · doi:10.1089/jmf.2009.0096 · Cited by 159 · cited 1× · see citing works
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“Evening ingestion of α-lactalbumin resulted in a 130% increase in tryptophan:LNAA prior to bed and modest but significant reduction in morning sleepiness and improved alertness the following morning [55].”
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NIEMAN, D. C., HENSON, D. A., MCANULTY, S. R., MCANULTY, L. S., MORROW, J. D., AHMED, A., & HEWARD, C. B. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000135778.57355.ca · Cited by 131 · cited 3× · see citing works
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“The effects were attributed to the synergy between magnesium, zinc and melatonin [75].”
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“Antioxidant consumption may influence recovery from exercise but may also influence sleep since sleep regulation is influenced by pro-inflammatory cytokines [59].”
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“Recently the term Chrononutrition has been used to describe the interaction between food and the circadian system [39].”
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“Tryptophan depletion studies have demonstrated decreased tryptophan plasma concentrations affected sleep fragmentation (arousal index (events/h)), REM sleep latency (the interval between first epoch of stage 2 and the first epoch of REM sleep), and REM density (the cumulated duration of each REM burst divided by the d…”
ResultDietary Antioxidants as Modifiers of Physiologic Adaptations to Exercise
MANKOWSKI, R. T., ANTON, S. D., BUFORD, T. W., & LEEUWENBURGH, C. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000620 · Cited by 83 · cited 1× · see citing works
“While it has been reported that high doses of antioxidants could reduce training adaptations of muscle mitochondrial biogenesis and VO2max, not all antioxidant studies have demonstrated negative effects and it has been suggested that the specific antioxidant used, the dose and timing of ingestion all affect outcomes […”
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“8%) [53], indicating that relatively small doses (250 mg) of dietary tryptophan can positively impact sleep.”
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An integrative review of sleep for nutrition professionals
Golem, D. L., Martin-Biggers, J. T., Koenings, M. M., Davis, K. F., & Byrd-Bredbenner, C. (2014) · Advances in Nutrition · doi:10.3945/an.114.006809 · Cited by 77 · see citing works
Bed-time food supplements and sleep: Effects of different carbohydrate levels
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“Consumption of a high-carbohydrate meal (130 g) when compared to a low-carbohydrate meal (47 g), or a meal containing no carbohydrate, 45 min before bedtime increased REM and decreased light sleep and wakefulness [47].”
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“05) increase plasma vitamin C [74] vitamin E [71] and lutein/zeaxanthin concentrations [71,74].”
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“, C-reactive protein [CRP] and Interleukin-6 [IL-6]) predict body mass gain in older adults [23] and type 2 diabetes [24].”
BackgroundSleepiness/alertness among healthy evening and morning type individuals
Rosenthal, L. D., Day, R. C., Gerhardstein, R. R., et al. (2001) · Sleep Medicine · doi:10.1016/s1389-9457(00)00047-2 · Cited by 62 · cited 2× · see citing works
“Core body temperature and melatonin rhythms are markers of C [11].”
BackgroundPhenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress
Galano, A., Castañeda-Arriaga, R., Pérez-González, A., Tan, D.-X., & Reiter, R. (2016) · Molecules · doi:10.3390/molecules21111442 · Cited by 60 · cited 1× · see citing works
“Melatonin also increases the protective effects of glutathione, vitamin C and trolox, through regeneration by electron transfer processes [69].”
BackgroundPhysiological links between circadian rhythms, metabolism and nutrition
Johnston, J. D. (2014) · Experimental Physiology · doi:10.1113/expphysiol.2014.078295 · Cited by 59 · cited 1× · see citing works
“Give that Process C can be modified by exogenous cues [27], there is scope for investigation of nutrition interventions to enhance sleep quality and quantity.”
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“05) increase plasma vitamin C [74] vitamin E [71] and lutein/zeaxanthin concentrations [71,74].”
BackgroundNight milking adds value to cow’s milk
Milagres, M. P., Minim, V. P. R., Minim, L. A., Simiqueli, A. A., Moraes, L. E. S., & Martino, H. S. D. (2014) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6480 · Cited by 44 · cited 2× · see citing works
“, milk) could affect changes in core temperature improving sleep quality [51].”
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Mid-morning tryptophan depletion delays REM sleep onset in healthy subjects
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Acute effects of low doses of melatonin on the sleep of young healthy subjects
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“The SCN has melatonin receptor cells, as darkness falls, melatonin is secreted by the pineal gland making the individual sleepy [15].”
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Flagged first, then by citations
3 of the 75 references couldn’t be matched to a known paper.
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Sejbuk, M., Mirończuk-Chodakowska, I., & Witkowska, A. M. (2022) · Nutrients · doi:10.3390/nu14091912 · Cited by 388 · see citing works
“The absorption of melatonin has a positive effect on the quality of sleep by increasing the propensity to sleep and by increasing the duration of sleep [42].”
BackgroundDiet, Sleep, and Mental Health: Insights from the UK Biobank Study
Hepsomali, P., & Groeger, J. A. (2021) · Nutrients · doi:10.3390/nu13082573 · Cited by 121 · see citing works
Impact of Melatonin on Skeletal Muscle and Exercise
Stacchiotti, A., Favero, G., & Rodella, L. F. (2020) · Cells · doi:10.3390/cells9020288 · Cited by 115 · see citing works
The Impact of Sleep Interventions on Athletic Performance: A Systematic Review
Cunha, L. A., Costa, J. A., Marques, E. A., Brito, J., Lastella, M., & Figueiredo, P. (2023) · Sports Medicine - Open · doi:10.1186/s40798-023-00599-z · Cited by 97 · see citing works
“To date, studies examining the sleep/wake behavior of athletes have focused on nutrition [13, 20], sleep hygiene [21], and sleep extension/napping [22, 23].”
BackgroundBruinvels, G., Hackney, A. C., & Pedlar, C. R. (2022) · Sports Medicine · doi:10.1007/s40279-022-01691-2 · Cited by 82 · see citing works
Bonilla, D. A., Pérez-Idárraga, A., Odriozola-Martínez, A., & Kreider, R. B. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18010103 · Cited by 77 · see citing works
Drăgoi, C. M., Nicolae, A. C., Ungurianu, A., Margina, D. M., Grădinaru, D., & Dumitrescu, I.-B. (2024) · Cells · doi:10.3390/cells13020138 · Cited by 71 · see citing works
“Supplementation of tryptophan has been shown to have a cognitive benefit, but has not consistently been shown to reduce fatigue during physical activity [14,67,68].”
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Work-related stress, psychophysiological strain, and recovery among on-site construction personnel
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Taheri, M., Irandoust, K., Reynoso-Sánchez, L. F., Muñoz-Helú, H., Cruz-Morales, K. N., Ramírez, R. T., Mirmoezzi, M., Youzbashi, L., Mirakhori, F., Dergaa, I., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1143340 · Cited by 48 · see citing works
The Association between Diet and Sleep Quality among Spanish University Students
Arbués, E. R., Granada-López, J. M., Martínez-Abadía, B., Echániz-Serrano, E., Antón‐Solanas, I., & Jerue, B. A. (2022) · Nutrients · doi:10.3390/nu14163291 · Cited by 48 · see citing works
“Likewise, eating nuts [30], dairy [31,32] and some fruits, such as cherries or kiwis [33], may be beneficial for sleep.”
BackgroundWirth, M. D., Jessup, A., Turner‐McGrievy, G. M., Shivappa, N., Hurley, T. G., & Hébert, J. R. (2020) · SLEEP · doi:10.1093/sleep/zsaa093 · Cited by 40 · see citing works
“What follows are just a few examples of mechanisms that are described in detail elsewhere [20, 71, 72].”
BackgroundPortuguese Football Federation consensus statement 2020: nutrition and performance in football
Abreu, R., Figueiredo, P., Beckert, P., Marques, J. P., Amorim, S., Caetano, C., Carvalho, P., Sá, C., Cotovio, R., Cruz, J., et al. (2021) · BMJ Open Sport & Exercise Medicine · doi:10.1136/bmjsem-2021-001082 · Cited by 38 · see citing works
Nutritional Interventions to Improve Sleep in Team-Sport Athletes: A Narrative Review
Gratwicke, M., Miles, K. H., Pyne, D. B., Pumpa, K. L., & Clark, B. (2021) · Nutrients · doi:10.3390/nu13051586 · Cited by 39 · see citing works
“The reported anti-inflammatory properties may influence the pro-inflammatory cytokines involved in sleep regulation and also the recovery process after exercise [10,52].”
BackgroundInfluentialSleep, Nutrition, and Injury Risk in Adolescent Athletes: A Narrative Review
Mason, L., Connolly, J., Devenney, L. E., Lacey, K., O’Donovan, J., & Doherty, R. (2023) · Nutrients · doi:10.3390/nu15245101 · Cited by 42 · see citing works
“Both sleep and nutrition are viewed as modifiable facilitators for recovery in athletes [22,38,45,65,162–164, 168,”
BackgroundInfluentialSelf-citationBavaresco, D. V., da Rosa, M. I., Uggioni, M. L. R., Ferraz, S. D., Pacheco, T. R., Toé, H. C. Z. D., da Silveira, A. P., Quadros, L. F. A., Daminelli, T., Varela, R. B., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.03.073 · Cited by 31 · see citing works
Evolution of the use of sports supplements
Alonso, M. R., & Fernández‐Garcia, B. (2020) · PharmaNutrition · doi:10.1016/j.phanu.2020.100239 · Cited by 32 · see citing works
Juliana, N., Azmi, L., Effendy, N. M., Teng, N. I. M. F., Abu, I. F., Bakar, N. N. A., Azmani, S., Yazit, N. A. A., Kadiman, S., & Das, S. (2023) · Nutrients · doi:10.3390/nu15030734 · Cited by 32 · see citing works
Sports and Immunity, from the recreational to the elite athlete
Baskerville, R., Castell, L. M., & Bermon, S. (2024) · Infectious Diseases Now · doi:10.1016/j.idnow.2024.104893 · Cited by 38 · see citing works
Dumar, A. M., Huntington, A. F., Rogers, R. R., Kopec, T. J., Williams, T. D., & Ballmann, C. G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18020412 · Cited by 32 · see citing works
“Because of performance decrements during AM times, athletes and competitors commonly use behavioral and dietary modifications to optimize training and performance during various times of day [8].”
BackgroundLangan‐Evans, C., Hearris, M. A., Gallagher, C., LONG, S., Thomas, C., Moss, A., CHEUNG, W., Howatson, G., & Morton, J. P. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003040 · Cited by 29 · see citing works
“Copyright © 2022 by the American College of Sports Medicine Sleep is an essential process in aiding the recovery of several psychophysiological functions, including learning and memory, the central nervous and metabolic cost of daytime activities, and the restoration of the immune and endocrine systems (1).”
BackgroundThe Relationship Between Diet and Sleep in Older Adults: a Narrative Review
Gupta, C. C., Irwin, C. G., Vincent, G. E., & Khalesi, S. (2021) · Current Nutrition Reports · doi:10.1007/s13668-021-00362-4 · Cited by 30 · see citing works
Castellucci, B., Barrea, L., Laudisio, D., Aprano, S., Pugliese, G., Savastano, S., Colao, A., & Muscogiuri, G. (2020) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2020.1851659 · Cited by 28 · see citing works
“Even meal timing, in fact, in addition to the composition in micro and macronutrients, affect sleep and it has been shown that eating just before bedtime increases the risk of SD (Dollander 2002).”
BackgroundSutanto, C. N., Loh, W. W., Toh, D. W. K., Lee, D. P. S., & Kim, J. E. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.832341 · Cited by 27 · see citing works
Zhu, H., Yang, X., & Zhao, Y. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06419 · Cited by 27 · see citing works
López‐Gil, J. F., Smith, L., Victoria‐Montesinos, D., Gutiérrez‐Espinoza, H., López, P. J. T., & Mesas, A. E. (2023) · Nutrients · doi:10.3390/nu15030665 · Cited by 24 · see citing works
“Indeed, deficiency in this vitamin has been associated with insomnia and sleep disturbances, possibly because vitamin B9 seems to be involved in the conversion of tryptophan into serotonin [33].”
BackgroundNobarı, H., Banihashemi, M., Saedmocheshi, S., Prieto-González, P., & Oliveira, R. F. S. (2023) · Science Progress · doi:10.1177/00368504231206265 · Cited by 32 · see citing works
“54 Several nutrients have an impact on sleep, including carbohydrates (high glycemic index dinners reduce sleep delay), protein (dairy consumption may lengthen sleep), ethanol/ alcohol consumption (associated with poor sleep quality), 48,55 and caffeine (lengthens sleep delay and total sleep time).”
BackgroundOptimisation and Validation of a Nutritional Intervention to Enhance Sleep Quality and Quantity
Halson, S. L., Shaw, G., Versey, N. G., Miller, D. J., Sargent, C., Roach, G. D., Nyman, L. R., Carter, J. M., & Baar, K. (2020) · Nutrients · doi:10.3390/nu12092579 · Cited by 23 · see citing works
“Tart cherries have high concentrations of melatonin and other phenolic compounds which may have antioxidant and anti-inflammatory properties [16] that could potentially positively influence sleep.”
BackgroundExamining the role of systemic chronic inflammation in diet and sleep relationship
Hepsomali, P., & Groeger, J. A. (2022) · Journal of Psychopharmacology · doi:10.1177/02698811221112932 · Cited by 23 · see citing works
“It is well known that some nutrients, nutritional deficiencies or abundances and food items may affect sleep (Doherty et al., 2019).”
BackgroundCircadian rhythm in sportspersons and athletic performance: A mini review
Pradhan, S., Parganiha, A., Agashe, C., & Pati, A. K. (2024) · Chronobiology International · doi:10.1080/07420528.2024.2305663 · Cited by 23 · see citing works
Dietary inflammatory index (DII) and sleep quality, duration, and timing: A systematic review
Farrell, E. T., Hébert, J. R., Heflin, K., Davis, J. E., Turner‐McGrievy, G. M., & Wirth, M. D. (2024) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2024.101964 · Cited by 22 · see citing works
Sleep and Athletic Performance: A Multidimensional Review of Physiological and Molecular Mechanisms
Kaczmarek, F., Bartkowiak-Wieczorek, J., Matecka, M., Jenczylik, K., Brzezińska, K., Gajniak, P., Marchwiak, S., Kaczmarek, K., Nowak, M., Kmiecik, M., et al. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217606 · Cited by 40 · see citing works
Bulman, A., D'Cunha, N. M., Marx, W., McKune, A. J., Jani, R., & Naumovski, N. (2021) · Beverages · doi:10.3390/beverages7020033 · Cited by 20 · see citing works
Wu, H., Su, W., Huang, S., Xiao, Y., & Lu, L. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.942513 · Cited by 19 · see citing works
“Sleep impacts biological function, physiological recovery, learning, memory, and cognition (Doherty et al., 2019).”
BackgroundRhon, D. I., Fritz, J. M., Greenlee, T. A., Dry, K. E., Mayhew, R. J., Laugesen, M. C., Dragusin, E., & Teyhen, D. S. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-03013-y · Cited by 21 · see citing works
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“Kiwi is rich in vitamins C and E and has a high antioxidant capacity, which is protective against free-radical damage; it is also a source of folate, which, when deficient, is related to insomnia [73].”
BackgroundDietary Inflammatory Index, Sleep Duration, and Sleep Quality: A Systematic Review
Coxon, C., Nishihira, J., & Hepsomali, P. (2024) · Nutrients · doi:10.3390/nu16060890 · Cited by 21 · see citing works
“Poor diet, a leading risk factor for noncommunicable diseases, is linked to poor sleep outcomes [1].”
BackgroundVlahoyiannis, A., Aphamis, G., Eddin, D. A., & Giannaki, C. D. (2020) · Journal of Sports Sciences · doi:10.1080/02640414.2020.1812194 · Cited by 17 · see citing works
Wirth, M. D., Fekedulegn, D. B., Andrew, M. E., McLain, A. C., Burch, J. B., Davis, J. E., Hébert, J. R., & Violanti, J. M. (2021) · Journal of Sleep Research · doi:10.1111/jsr.13543 · Cited by 17 · see citing works
“Carbohydrate consumption may increase tryptophan availability for later synthesis of serotonin and melatonin, which may facilitate sleep (Doherty et al., 2019).”
BackgroundTung, H., Chen, K., Chou, C.-P., Belcastro, F. P., Hsu, H., & Kuo, C.-F. (2022) · Journal of Applied Gerontology · doi:10.1177/07334648221141413 · Cited by 16 · see citing works
“Sleep disturbance and insufficiency may trigger inflammatory reactions, and sleep quality affects metabolic secretions, nutrient absorption, and cell growth and repair (Doherty et al., 2019; Knowles et al., 2018; Yang et al., 2019).”
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“Sleep has a restorative effect on the endocrine and the immune system, supports the recovery of the nervous system and has a fundamental role in memory, learning and in synaptic plasticity.(45) Adequate sleep is fundamental for the preservation ofmetabolic equilibrium.”
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“As several nutrients interact with neurotransmitters that help regulate the sleep–wake cycle, there is a growing interest in dietary strategies that promote sleep [7].”
BackgroundWAS POSTPONING THE TOKYO 2020 OLYMPIC AND PARALYMPIC GAMES A CORRECT DECISION?
Guerreiro, R. D. C., Silva, A., Andrade, H. D. A., Grade, I., Vital, R., da Silva, H. G. V., da Silva, F. R., & de Mello, M. T. (2020) · Revista Brasileira de Medicina do Esporte · doi:10.1590/1517-8692202026030036 · Cited by 15 · see citing works
Sleep quality and its associated factors among patients with tuberculosis: A cross-sectional study
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Elements of Sleep Breathing and Sleep-Deprivation Physiology in the Context of Athletic Performance
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Sleep and Nutrition in Athletes
Doherty, R., Madigan, S. M., Warrington, G. D., & Ellis, J. G. (2023) · Current Sleep Medicine Reports · doi:10.1007/s40675-022-00244-3 · Cited by 13 · see citing works
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“…and the systemic immune-inflammation index, indicating that the favorable link between diet quality and inflammatory burden may be partly realized through physical activity, thereby supporting an integrated lifestyle framework for understanding student-athletes’ health behavior patterns [24,25].”
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A Delayed Evening Meal Enhances Sleep Quality in Young Rugby Players
Lehmann, L., Saidi, O., Giacomoni, M., Sordo, G. C. D., Maso, F., Margaritis, I., & Duché, P. (2022) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2022-0014 · Cited by 11 · see citing works
Hsu, L.-M., Chen, H., Wu, P.-C., & Hua, K. (2023) · The Chinese Journal of Physiology · doi:10.4103/cjop.cjop-d-23-00043 · Cited by 11 · see citing works
Chen, Q., Fan, R., Song, L., Wang, S., You, M., Cai, M., Wu, Y., Li, Y., & Xu, M. (2024) · Food & Function · doi:10.1039/d4fo01303d · Cited by 11 · see citing works
Ren, R., Huang, R., Li, Y., Wang, W., Ye, X., Li, X., Zhang, R., Peng, Y., & Wang, D. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.12.020 · Cited by 11 · see citing works
Are Circadian Rhythms a New Frontier in Athletic Performance?
Simmons, N., Mandal, S., Paton, B. M., & Ahmed, I. (2022) · Current Sports Medicine Reports · doi:10.1249/jsr.0000000000000929 · Cited by 12 · see citing works
Śliż, D., Wiecha, S., Gąsior, J. S., Kasiak, P. S., Ulaszewska, K., Lewandowski, M., Barylski, M., & Mamcarz, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12083002 · Cited by 17 · see citing works
“For EAs, the correct quality and duration of sleep is essential because it affects physical and mental regeneration, which are necessary for achieving high sports results [42].”
BackgroundSocial jet lag and mental health outcomes: A systematic review and meta-analysis
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Nutritional interventions in treating menopause-related sleep disturbances: a systematic review
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“tive sleep and promote exogenous melatonin levels, or tryptophan-rich foods.(19) These could potentially be tri-”
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“Numerous studies have also mentioned the antidepressant, sedative, anxiolytic, analgesic, antioxidant, and sleep-enhancing properties of basil (Al-Ghurabi, 2014; Doherty et al., 2019; Neamati, Talebi, Hosseini, Hossein Boskabady, & Beheshti, 2016; Rabbani et al., 2015).”
BackgroundContemporary Variables that Impact Sleep and Development in Female Adolescent Swimmers and Gymnasts
Bartholomew, J. N., Gilligan, C., & Spence, A. (2021) · Sports Medicine - Open · doi:10.1186/s40798-021-00331-9 · Cited by 9 · see citing works
Factors Affecting Psychological Dynamics of Esports Athletes
Nadhirah, N. A., Hidayat, A. A., Suryana, D., Saripah, I., & Suryahadikusumah, A. R. (2023) · Journal of Education and Counseling (JECO) · doi:10.32627/jeco.v3i1.629 · Cited by 9 · see citing works
“For athletes to perform at a high level, rest and sleep are essential things required to optimize the necessary hormones to reduce stress, as well as maximize their cognitive processes and memory usage (Bibi et al. 2019); these two things are crucial for esports athletes (Doherty, 2019).”
BackgroundProtein intake and its association with sleep quality: results from 3 prospective cohort studies
Wirth, J., Lin, K., Brennan, L., Wu, K., & Giovannucci, E. L. (2024) · European Journal of Clinical Nutrition · doi:10.1038/s41430-024-01414-y · Cited by 10 · see citing works
“In addition, a narrative review has reported an increased plasma tryptophan level and tryptophan/LNAA ratio with higher carbohydrate intake [31].”
Yan, Z., & Wang, L. (2025) · PLoS ONE · doi:10.1371/journal.pone.0319813 · Cited by 11 · see citing works
“Collectively, these functions are essential for sports recovery and performance [45].”
Chica-Latorre, S., Knight-Agarwal, C. R., McKune, A. J., & Minehan, M. (2025) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2025.06.005 · Cited by 13 · see citing works
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Good Sleep as an Important Pillar for a Healthy Life
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“Furthermore, numerous previous studies have demonstrated the importance of sleep in health and performance [7,8].”
BackgroundChrétien, A., d’Arripe-Longueville, F., Haffner, K., Hayotte, M., Bernier, M., & Vuillemin, A. (2023) · International Journal of Qualitative Studies on Health and Well-Being · doi:10.1080/17482631.2023.2251235 · Cited by 8 · see citing works
“The literature highlights the relationship between athletes’ nutrition and the quality of their sleep (Doherty & Warrington, 2019).”
BackgroundPreventing or promoting muscle injuries? Strength training as a risk factor in professional football
Balagué, N., Hristovski, R., Pol, R., et al. (2024) · Apunts Sports Medicine · doi:10.1016/j.apunsm.2024.100462 · Cited by 8 · see citing works
Literature review: nutrition supplementation for muscle fatigue in athletes
Mardiana, M., Kartini, A., Sutiningsih, D., Suroto, S., & Muhtar, M. S. (2023) · Jurnal Keolahragaan · doi:10.21831/jk.v11i1.46486 · Cited by 7 · see citing works
The Sleep, Recovery, and Nutrition Characteristics of Elite Adolescent Athletes
Mason, L., Connolly, J., Devenney, L. E., Lacey, K., O’Donovan, J., Faulkner, M., & Doherty, R. (2025) · Sports · doi:10.3390/sports13020050 · Cited by 11 · see citing works
Self-citationNutrition Strategies to Promote Sleep in Elite Athletes: A Scoping Review
Rackard, G., Madigan, S. M., Connolly, J., Keaver, L., Ryan, L., & Doherty, R. (2025) · Sports · doi:10.3390/sports13100342 · Cited by 9 · see citing works
“The potential for nutrition to improve sleep is clear; however, the lack of intervention studies specifically for elite athletes [3,4,6,9,29], and this scoping review justified the aim to offer practitioners clarity on context-specific nutrition interventions.”
Self-citationCurrent Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes
Przewłócka, K., Korewo-Labelle, D., Berezka, P., Karnia, M. J., & Kaczor, J. J. (2024) · Nutrients · doi:10.3390/nu16121842 · Cited by 7 · see citing works
“As a result, reduced immunity and increased vulnerability to infections were observed [35].”
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A practical nutritional guideline to manage neuroendocrine neoplasms through chronotype and sleep
Muscogiuri, G., Zanata, I., Barrea, L., Cozzolino, A., Filice, E., Messina, E., Colao, A., & Faggiano, A. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2047882 · Cited by 7 · see citing works
Nutritional Concerns for the Artistic Athlete
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“Given that athletic performance is closely linked to sleep patterns and quality [12,13], exogenous MEL supplementation has been investigated as a strategy to enhance sleep quality [14,15], ultimately improving physical and mental recovery after exercise [16].”
The Effect of Tart Cherry on Sleep Quality and Sleep Disorders: A Systematic Review
Barforoush, F., Ebrahimi, S., Abdar, M., Khademi, S., & Morshedzadeh, N. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70923 · Cited by 7 · see citing works
“However, dietary interventions such as melatonin, kiwi, tart cherry juice, or tryptophan-rich diets can be effective in improving sleep quality naturally and without drug side effects (Doherty et al. 2019).”
The Mechanisms of Magnesium in Sleep Disorders
He, C., Wang, B., Chen, X., Xu, J., Yang, Y., & Yuan, M. (2025) · Nature and Science of Sleep · doi:10.2147/nss.s552646 · Cited by 6 · see citing works
“19 Current guidelines recommend that adults maintain optimal health and daytime performance by achieving a minimum of 7 hours of total sleep per night with a sleep efficiency of at least 85%.”
Nutritional geometry framework of sleep
Lai, M.-L., Li, A., Senior, A. M., Neely, G. G., Simpson, S. J., & Wang, Q. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121381 · Cited by 7 · see citing works
Association between Selenium Intake and Optimal Sleep Duration: A National Longitudinal Study
Zhao, L., Li, S., Zhu, Y., Wang, T., Su, Y., Shi, Z., Zhang, Y., & Zhao, Y. (2023) · Nutrients · doi:10.3390/nu15020397 · Cited by 6 · see citing works
“Antioxidant consumption may influence sleep because sleep duration can be affected by pro-inflammatory cytokines [37,38].”
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“In this sense, chrononutritional interventions can represent cost-effective strategies with a direct impact on weight control [74].”
BackgroundPost-Exercise Recovery Strategies in Basketball: Practical Applications Based on Scientific Evidence
Huyghe, T., Calleja-González, J., & Terrados, N. (2020) · Springer eBooks · doi:10.1007/978-3-662-61070-1_63 · Cited by 6 · see citing works
Bidirectional effects of physical activity and sleep on health: evidence and future directions
Clemente-Suárez, V., Redondo-Flórez, L., Beltrán-Velasco, A. I., Ramos-Campo, D., Ruisoto, P., Yáñez-Sepúlveda, R., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2026) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2026.1739588 · Cited by 4 · see citing works
Waking up “We” or “I”? How Start Temporal Landmarks Influence Arousal Product Preferences
Liang, S., Lan, B., Li, R., Zhang, M., Chu, Y., Teng, L., & He, L. (2023) · Behavioral Sciences · doi:10.3390/bs13010067 · Cited by 6 · see citing works
“Coffee can provide an immediate energy boost and sustain vitality [2,3], whereas milk can relax the mind and help the brain calm down [4].”
BackgroundNutritional Strategies for Peak Performance: Guidelines for Athletes' Optimal Fueling and Recovery
Ceylan, H. (2023) · Health Nexus · doi:10.61838/kman.hn.1.4.11 · Cited by 5 · see citing works
Gao, Y., & Wang, L. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1382068 · Cited by 6 · see citing works
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“…these factors, proper nutrition has been found to directly impact athletic performance (Thomas et al. 2016) and to indirectly impact sports performance through psychosocial determinants such as sleep (Doherty et al. 2019) and stress (Khan and Khan 2016) or overall well-being (Conner et al. 2015).”
The Effect of Nutrition Knowledge on Nutritional Status in Sport Science Students
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Analysis of energy requirements and nutritional needs of rock climbing athletes
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Personalized Nutritional Assessment and Intervention for Athletes: A Network Physiology Approach
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Practical Guidance to Optimize Postmatch Recovery in Elite Male and Female Soccer: A Review
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Sleep, nutrition, and supplements: Implications for athletes
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- Authors
- Doherty, R., Madigan, S., Warrington, G., & Ellis, J.
- Affiliations
- Letterkenny Institute of Technology (IE)
- Sport Ireland Institute (IE)
- University of Limerick (IE)
- Northumbria University (GB)
- Corresponding author
- Doherty, Rónán
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2019-04-11
- Volume
- 11
- Issue
- 4
- Pages
- 822
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC6520871
- OpenAlex
- W2938906146
- Semantic Scholar
- f51ed80aa0d48ac433b8a28592e9cbf85226e685
- Cited by
- 186
- References
- 75
- Citations by year
- 2026: 22 · 2025: 34 · 2024: 31 · 2023: 31 · 2022: 28 · 2021: 23 · 2020: 15 · 2019: 1
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- University of Limerick Institutional Repository (University of Limerick) (acceptedVersion, other-oa)
- Northumbria Research Link (Northumbria University) (submittedVersion)
- Arrow@dit (Dublin Institute of Technology) (submittedVersion, cc-by-nc-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by-nc-sa)
- Lenus, The Irish Health Repository (Dr Steevens Hospital Library) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- sleep, nutrition, athletes, sleep quality, sleep duration, sleep disorders, inflammation, melatonin, tryptophan, tart cherry juice, kiwifruit, micronutrients, carbohydrate intake, immune system, recovery, functional foods, sleep health
- MeSH terms
- Prunus avium, Antioxidants, Circadian Rhythm, Diet, Dietary Carbohydrates, Fruit, Humans, Melatonin, Nutritional Physiological Phenomena, Sleep, Sleep Wake Disorders, Tryptophan, Vitamin B Complex, Glycemic Index, Athletic Performance, Athletes
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