The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The Role of the Cerebellum in Schizophrenia: an Update of Clinical, Cognitive, and Functional Evidences
Open accessAbstract
The role of the cerebellum in schizophrenia has been highlighted by Andreasen's hypothesis of "cognitive dysmetria," which suggests a general dyscoordination of sensorimotor and mental processes. Studies in schizophrenic patients have brought observations supporting a cerebellar impairment: high prevalence of neurological soft signs, dyscoordination, abnormal posture and propioception, impaired eyeblink conditioning, impaired adaptation of the vestibular-ocular reflex or procedural learning tests, and lastly functional neuroimaging studies correlating poor cognitive performances with abnormal cerebellar activations. Despite those compelling evidences, there has been, to our knowledge, no recent review on the clinical, cognitive, and functional literature supporting the role of the cerebellum in schizophrenia. We conducted a Medline research focusing on cerebellar dysfunctions in schizophrenia. Emphasis was given to recent literature (after 1998). The picture arising from this review is heterogeneous. While in some domains, the role of the cerebellum seems clearly defined (ie, neurological soft signs, posture, or equilibrium), in other domains, the cerebellar contribution to schizophrenia seems limited or indirect (ie, cognition) if present at all (ie, affectivity). Functional models of the cerebellum are proposed as a background for interpreting these results.
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Citations
Cites
The functional neuroanatomy of autobiographical memory: a meta-analysis
Svoboda, E., McKinnon, M. C., & Levine, B. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.05.023 · Cited by 1,274
Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms
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Evidence for sensory prediction deficits in schizophrenia
Shergill, S. S., Samson, G., Bays, P. M., Frith, C. D., & Wolpert, D. M. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.12.2384 · Cited by 432
The cerebellum on the rise in human emotion
Schutter, D. J. L. G., & Van Honk, J. (2005) · The Cerebellum · doi:10.1080/14734220500348584 · Cited by 261
Event-Related fMRI of Frontotemporal Activity During Word Encoding and Recognition in Schizophrenia
Ragland, J. D., Gur, R. C., Valdez, J., Turetsky, B. I., Elliott, M., Kohler, C., Siegel, S., Kanes, S., & Gur, R. E. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.6.1004 · Cited by 206
Imaging the mental components of a planning task
Rowe, J. B., Owen, A. M., Johnsrude, I. S., & Passingham, R. E. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(00)00109-3 · Cited by 151
Neural response to emotional prosody in schizophrenia and in bipolar affective disorder
Mitchell, R. L. C., Elliott, R., Barry, M., Cruttenden, A., & Woodruff, P. W. R. (2004) · British Journal of Psychiatry · doi:10.1192/bjp.184.3.223 · Cited by 128
Cited by
The role of the cerebellum in schizophrenia
Andreasen, N. C., & Pierson, R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.01.003 · Cited by 669
Cerebellar modulation of the reward circuitry and social behavior
Carta, I., Chen, C. H., Schott, A. L., Dorizan, S., & Khodakhah, K. (2019) · Science · doi:10.1126/science.aav0581 · Cited by 601
Interaction of language, auditory and memory brain networks in auditory verbal hallucinations
Ćurčić-Blake, B., Ford, J. M., Hubl, D., Orlov, N. D., Sommer, I. E., Waters, F., Allen, P., Jardri, R., Woodruff, P. W., David, O., et al. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.11.002 · Cited by 224
“Cerebellum is important for brain synchrony and action prediction (D'Angelo and Casali, 2013) by coordinating and modulating cortical activity (Picard et al., 2008).”
BackgroundCerebellum and Detection of Sequences, from Perception to Cognition
Molinari, M., Chiricozzi, F. R., Clausi, S., Tedesco, A. M., De Lisa, M., & Leggio, M. G. (2008) · The Cerebellum · doi:10.1007/s12311-008-0060-x · Cited by 173
Eng, G. K., Sim, K., & Chen, S.-H. A. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.03.002 · Cited by 148
Metadata
- Authors
- Picard, H., Amado, I., Mouchet-Mages, S., Olie, J.-P., & Krebs, M.-O.
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-10-27
- Volume
- 34
- Issue
- 1
- Pages
- 155-172
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W2104822838
- Cited by
- 284
- References
- 7
- FWCI
- 8.01
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Picard, H., Amado, I., Mouchet-Mages, S., Olie, J.-P., & Krebs, M.-O. (2007). The Role of the Cerebellum in Schizophrenia: an Update of Clinical, Cognitive, and Functional Evidences. Schizophrenia Bulletin. https://doi.org/10.1093/schbul/sbm049
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