Neuroendocrine Consequences of Prenatal Androgen Exposure in the Female Rat: Absence of Luteinizing Hormone Surges, Suppression of Progesterone Receptor Gene Expression, and Acceleration of the Gonadotropin-Releasing Hormone Pulse Generator1

Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study

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Plasma Testosterone and Progesterone Titers of Pregnant Rats, Their Male and Female Fetuses, and Neonatal Offspring*

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A 24-HOUR PERIODICITY IN THE “LH-RELEASE APPARATUS” OF FEMALE RATS, DISCLOSED BY BARBITURATE SEDATION1

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Oestrogen modulates progestin receptor concentrations in some rat brain regions but not in others

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EVIDENCE THAT THE HYPOTHALAMUS IS RESPONSIBLE FOR ANDROGEN-INDUCED STERILITY IN THE FEMALE RAT1

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Discrete Lesions Reveal Functional Heterogeneity of Suprachiasmatic Structures in Regulation of Gonadotropin Secretion in the Female Rat

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Progestin Receptors in Rat Brain: Distribution and Properties of Cytoplasmic Progestin-Binding Sites*

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Transient Expression of Progesterone Receptor Messenger RNA in Ovarian Granuiosa Cells after the Preovulatory Luteinizing Hormone Surge

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Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: Implications for a common fertility disorder

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Brain masculinization requires androgen receptor function

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Neurochemical architecture of the human striatum

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Abolition of male sexual behaviors in mice lacking estrogen receptors α and β (αβERKO)

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Modifications of Testosterone-Dependent Behaviors by Estrogen Receptor-α Gene Disruption in Male Mice1

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New Concepts of the Neuroendocrine Regulation of Gonadotropin Surges in Rats

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Masculine Sexual Behavior Is Disrupted in Male and Female Mice Lacking a Functional Estrogen Receptor α Gene

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Expression and Estrogen Regulation of Progesterone Receptor mRNA in Neurons of the Mediobasal Hypothalamus: Anin SituHybridization Study

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Modification of ovulatory mechanisms by postnatal administration of estrogen to the rat

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Influence of perinatal androgen on the sexually dimorphic distribution of tyrosine hydroxylase-immunoreactive cells and fibers in the anteroventral periventricular nucleus of the rat

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Enduring consequences of neonatal treatment with antisense oligodeoxynucleotides to estrogen receptor messenger ribonucleic acid on sexual differentiation of rat brain

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Sexually dimorphic expression of estrogen receptor β in the anteroventral periventricular nucleus of the rat preoptic area: Implication in luteinizing hormone surge

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Estimating false-positive and false-negative errors in analyses of hormonal pulsatility

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Changes in Testicular Weight and Serum Gonadotropin and Testosterone Levels before, during, and after Birth in the Perinatal Rat*

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Effects of Castration and Chronic Steroid Treatments on Hypothalamic Gonadotropin-Releasing Hormone Content and Pituitary Gonadotropins in Male Wild-Type and Estrogen Receptor- Knockout Mice

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Absence of Gonadotropin Surges and Gonadotropin-Releasing Hormone Self-Priming in Ovariectomized (OVX), Estrogen (E2)-Treated, Progesterone Receptor Knockout (PRKO) Mice

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Prenatal exposure of female rhesus monkeys to testosterone propionate increases serum luteinizing hormone levels in adulthood

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Stimulation of Gonadotropin-Releasing Hormone Surges by Estrogen. I. Role of Hypothalamic Progesterone Receptors

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Sex Difference in Estradiol Regulation of Progestin Receptor mRNA in Rat Mediobasal Hypothalamus as Demonstrated by in situ Hybridization

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Regulation of the progesterone receptor gene by gonadotropins and cyclic adenosine 3',5'-monophosphate in rat granulosa cells.

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Distribution of cells containing progesterone receptor mRNA in the female rat di- and telencephalon: an in situ hybridization study

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Ovarian Steroid Regulation of Estrogen and Progesterone Receptor Messenger Ribonucleic Acid in the Anteroventral Periventricular Nucleus of the Rat

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Sex Differences in Progesterone Receptor Expression: A Potential Mechanism for Estradiol-Mediated Sexual Differentiation

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Suppression of spontaneous LH surges in estrogen-treated ovariectomized rats by microimplants of antiestrogens into the preoptic brain

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Fetal Programming: Prenatal Androgen Disrupts Positive Feedback Actions of Estradiol but Does Not Affect Timing of Puberty in Female Sheep1

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Sexual Differentiation of Aromatase Activity in the Rat Brain: Effects of Perinatal Steroid Exposure*

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Absence of androgen receptors in LHRH immunoreactive neurons

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Blockade of the Spontaneous Midcycle Gonadotropin Surge in Monkeys by RU 486: A Progesterone Antagonist or AgonistÓ*

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Fetal testosterone surge: specific modulations induced in male rats by maternal stress and/or alcohol consumption

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Effects of Prenatal Testosterone on Sexual Behavior, Reproductive Morphology and LH Secretion in the Female Rat

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Control of Pulsatile LH Release in Male Rats

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Regional sex differences in progestin receptor induction in the rat hypothalamus: effects of various doses of estradiol benzoate.

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Dihydrotestosterone may inhibit hypothalamo–pituitary–adrenal activity by acting through estrogen receptor in the male mouse

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Regulation of Gonadotropin-Releasing Hormone (GnRH) Gene Expression by 5α-Dihydrotestosterone in GnRH-Secreting GT1–7 Hypothalamic Neurons1

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Progesterone Receptor A and B Messenger Ribonucleic Acid Levels in the Anterior Pituitary of Rats Are Regulated by Estrogen1

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Differential Effects of the Perinatal Steroid Environment on Three Sexually Dimorphic Parameters of the Rat Brain1

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Organizational Effects of Testosterone via Aromatization on Feminine Reproductive Behavior and Neural Progestin Receptors in Rat Brain*

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Regulation and Expression of Progesterone Receptor mRNA Isoforms A and B in the Male and Female Rat Hypothalamus and Pituitary Following Oestrogen Treatment

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Prenatal Dihydrotestosterone Differentially Masculinizes Tonic and Surge Modes of Luteinizing Hormone Secretion in Sheep

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Stimulation of Gonadotropin-Releasing Hormone Surges by Estrogen. II. Role of Cyclic Adenosine 3',5'-Monophosphate

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Sexual Differentiation of the Surge Mode of Gonadotropin Secretion: Prenatal Androgens Abolish the Gonadotropin-Releasing Hormone Surge in the Sheep

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Changes in pituitary secretion during the early postnatal period and anovulatory syndrome induced by neonatal oestrogen or androgen in rats

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The antiprogestin RU486 delays the midcycle gonadotropin surge and ovulation in gonadotropin-releasing hormone-induced cycles

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Biological half-lives of [4–14C]testosterone and some of its esters after injection into the rat

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Prenatal Exposure of the Ovine Fetus to Androgens Sexually Differentiates the Steroid Feedback Mechanisms That Control Gonadotropin Releasing Hormone Secretion and Disrupts Ovarian Cycles

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Co-expression of steroid hormone receptors in opioid peptide-containing neurons correlates with patterns of gene expression during the estrous cycle

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The hormone-sensitive early postnatal periods for sexual differentiation of feminine behavior and luteinizing hormone secretion in male and female rats

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Administration of Dihydrotestosterone to Rhesus Monkeys Inhibits Gonadotropin-Stimulated Ovarian Steroidogenesis

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RU486 administration blocks neuropeptide Y potentiation of luteinizing hormone (LH)-releasing hormone-induced LH surges in proestrous rats

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Steroid Modulation of Neuropeptide Y-Induced Luteinizing Hormone Releasing Hormone Release from Median Eminence Fragments from Male Rats

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Prenatal Testosterone Masculinizes Synaptic Input to Gonadotropin-Releasing Hormone Neurons in Sheep1

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Lack of Gonadotropin-Positive Feedback in the Male Rat Is Associated with Lack of Estrogen-Induced Synaptic Plasticity in the Arcuate Nucleus

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Antiprogestins RU486 and ZK299 suppress basal and LHRH-stimulated FSH and LH secretion at pituitary level in the rat in an oestrous cycle stage-dependent manner

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Differential effects of aromatase inhibition on luteinizing hormone secretion in intact and castrated male cynomolgus macaques

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Influence of Estradiol and Progesterone on Pulsatile LH Secretion in 8-Day Ovariectomized Rats

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Sex differences in the responses of hypothalamic luteinizing hormone-releasing hormone and catecholamine systems to ovarian hormones and naloxone: implications for sexual differentiation of luteinizing hormone secretion in rats

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Effect of Neonatal Androgenization on Positive Feedback in Female Mice1

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Neonatal androgen abolishes clock-timed gonadotrophin release in prepubertal and adult female hamsters

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Control of Gonadotropin Secretion in the Ovine Fetus. IV. Male-Specific Entrainment of the Hypothalamic Control of Luteinizing Hormone Secretion by Testosterone in the Female Ovine Fetus*

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Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications

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The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited

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Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome

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Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies

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Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome

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Prenatal androgen excess enhances stimulation of the GNRH pulse in pubertal female rats

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Effects of experimental hyperandrogenemia on the female rat reproductive axis: Suppression of progesterone-receptor messenger RNA expression in the brain and blockade of luteinizing hormone surges

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Neonatal exposure to estradiol prevents the expression of ovarian hormone-induced luteinizing hormone and prolactin surges in adulthood but not antecedent changes in neuropeptide Y or adrenergic transmitter activity: Implications for sexual differentiation of gonadotropin secretion

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Prenatal Androgens Defeminize Activation of GnRH Neurons in Response to Estradiol Stimulation

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Prepubertal Development of Gonadotropin-Releasing Hormone Neuron Activity Is Altered by Sex, Age, and Prenatal Androgen Exposure

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