The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Oxidants and human disease: some new concepts 1
Abstract
Oxidant species such as superoxide radical ( ), hydrogen peroxide (H 2 O 2 ), hydroxyl radical (HO.), and lipid peroxides (LOOH) are becoming increasingly implicated in human disease. However, the question of whether such oxidants are a major cause of tissue injury in human disease or are merely produced during such injury has been difficult to answer because of inadequate experimental techniques, and possibly because of an overemphasis on lipid peroxidation as a mechanism of oxidant injury. Recent developments in methodology, in our understanding of the primary mechanism of oxidant toxicity to cells, and in concepts of antioxidant protection are reviewed. Good evidence now exists for some role of oxidant damage to tissues in the pathology of several human diseases, including rheumatoid arthritis, reperfusion injury, immune injury to lung and kidney, and cerebral trauma or ischemia. These have led to promising suggestions for new therapeutic approaches.— H alliwell , B. Oxidants and human disease: some new concepts. FASEB J. 1: 358‐364; 1987.
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Citations
Cites
Oxygen-Derived Free Radicals in Postischemic Tissue Injury
Epstein, F. H., & McCord, J. M. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501173120305 · Cited by 5,399
Gutteridge, J. M. C. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80626-3 · Cited by 629
Cross, A. R., & Jones, O. T. G. (1986) · Biochemical Journal · doi:10.1042/bj2370111 · Cited by 551
Biemond, P., van Eijk, H. G., Swaak, A. J., & Koster, J. F. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111364 · Cited by 380
Cited by
[1] Role of free radicals and catalytic metal ions in human disease: An overview
Halliwell, B., & Gutteridge, J. M. C. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)86093-b · Cited by 4,994
Self-citationReactive Oxygen Species and the Central Nervous System
Halliwell, B. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10990.x · Cited by 2,947
Self-citationFree Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases
Phaniendra, A., Jestadi, D. B., & Periyasamy, L. (2015) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-014-0446-0 · Cited by 2,886
DNA damage and oxygen radical toxicity
Imlay, J. A., & Linn, S. (1988) · Science · doi:10.1126/science.3287616 · Cited by 1,974
DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems
Halliwell, B., & Aruoma, O. I. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80347-6 · Cited by 1,537
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Metadata
- Authors
- Halliwell, B.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 1987-11
- Volume
- 1
- Issue
- 5
- Pages
- 358-364
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W2149855017
- Cited by
- 1,203
- References
- 4
- FWCI
- 41.98
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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