CoChat
Sign Up
Cited by 267Sleep and related disordersMusculoskeletal pain and rehabilitationFibromyalgia and Chronic Fatigue Syndrome Research

Major depression and insomnia in chronic pain

Wilson, Keith G., Eriksson, Mariane Y., D'Eon, Joyce L., Mikail, Samuel F., Emery, Patricia C.·2002·The Clinical Journal of Pain
DOI 10.1097/00002508-200203000-00002
Open this paper in CoChat — free account

Abstract

OBJECTIVES: Insomnia and depression are common problems for people with chronic pain, and previous research has found that each is correlated with measures of pain and disability. The goal of this study was to examine the combined impact of major depression and insomnia on individuals with chronic pain. METHODS: The participants were patients with chronic musculoskeletal pain who underwent evaluation at an interdisciplinary treatment center. On the basis of semistructured interviews, participants were classified in three groups depending on whether they: (1) met criteria for major depression with insomnia (n = 38); (2) had insomnia without major depression (n = 58); or (3) had neither insomnia nor major depression (n = 47). The groups were then compared on self-report measures that included the McGill Pain Questionnaire, the Beck Depression Inventory, and the Multidimensional Pain Inventory. RESULTS: Participants with major depression and insomnia reported the most difficulty on measures of affective distress, life control, interference, and pain severity, although the insomniac patients without major depression also had elevated scores on some measures. In regression analyses, insomnia severity ratings did not contribute uniquely to the prediction of psychosocial problems when depression was controlled, but they did contribute to the prediction of pain severity. CONCLUSIONS: These results suggest that patients with chronic pain and concurrent major depression and insomnia report the highest levels of pain-related impairment, but insomnia in the absence of major depression is also associated with increased pain and distress.

Integrity signals

Registry

Crossref · 10.1097/00002508-200203000-00002

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In the general population, depression is associated with a wide range of health, mental health, and neurological conditions, such as chronic pain, headaches and migraines, diabetes, low testosterone, cardiovascular/cerebrovascular/small vessel ischemic disease, PD, MCI, and AD.

    “In the general population, depression is associated with a wide range of health, mental health, and neurological conditions, such as 1) chronic pain [71–75]; 2) headaches and migraines [76–79]; 3) diabetes [80–82]; 4) low testosterone [83–85]; 5) cardiovascular, cerebrovascular, and small vessel ischemic disease [86–92]; 6) PD [93]; 7) MCI [94–96]; and 8) AD [97].”

    From The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features (2017) · cites this paper as [73]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Wilson, K. G., Eriksson, M. Y., D'Eon, J. L., Mikail, S. F., & Emery, P. C.
Affiliations
University of Ottawa (CA)
Corresponding author
Wilson, Keith G.
ORCID
Venue
The Clinical Journal of Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2002-03
Volume
18
Issue
2
Pages
77-83
ISSN
0749-8047 (ISSN-L)
DOI
10.1097/00002508-200203000-00002
OpenAlex
W2066517347
Cited by
267
References
39
Citations by year
2026: 3 · 2025: 4 · 2024: 7 · 2023: 12 · 2022: 7 · 2021: 11 · 2020: 12 · 2019: 11 · 2018: 5 · 2017: 14 · 2016: 14 · 2015: 17 · 2014: 17 · 2013: 9 · 2012: 16
FWCI
18.66
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
Keywords
major depressive disorder, insomnia, chronic pain, musculoskeletal pain, pain intensity, pain-related impairment, psychosocial problems, emotional distress, life control, multidisciplinary pain management
MeSH terms
Adult, Chronic Disease, Major Depressive Disorder, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Musculoskeletal Diseases, Pain, Pain Measurement, Surveys and Questionnaires, Regression Analysis, Self-Assessment, Comorbidity, Prevalence, Pain Clinics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review