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Cited by 155Thermoregulation and physiological responsesMuscle metabolism and nutritionCardiovascular and exercise physiology

Branched-chain amino acids prolong exercise during heat stress in men and women

MITTLEMAN, KAREN D., RICCI, MATTHEW R., BAILEY, STEPHEN P.·1998·Medicine & Science in Sports & Exercise
DOI 10.1097/00005768-199801000-00012
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Abstract

To assess the effect of branched-chain amino acids (BCAA) supplementation on endurance performance in the heat, six women and seven men participated in two trials of rest in the heat (Ta = 34.4 +/- 1.8 degrees C; rh = 39 +/- 14%), followed by 40% VO2peak exercise to exhaustion. Subjects ingested 5 mL x kg(-1) of a placebo (PLAC) or BCAA drink every 30 min. Cycle time to exhaustion increased during BCAA (153.1 +/- 13.3 vs 137.0 +/- 12.2 min, P < 0.05) for men and women. Plasma glucose was maintained at baseline values for both drinks; however, women had significantly higher concentrations (5.9 +/- 0.6 vs 4.0 +/- 0.2 mM, P < 0.05). Plasma free fatty acids and ammonia were not influenced by drink or gender but increased over time. BCAA resulted in a significant (P < 0.05) increase in plasma BCAA (1209 +/- 119 vs 496 +/- 44 microM), while F-TRP (9.6 +/- 0.9 vs 12.0 +/- 1.3 microM) and F-TRP:BCAA were decreased (0.009 +/- 0.001 vs 0.024 +/- 0.003 ND) in both men and women. Cardiovascular and thermoregulatory data were similar between treatments for all subjects. Psychological data were not influenced by BCAA. These results indicate BCAA supplementation prolongs moderate exercise performance in the heat.

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Crossref · 10.1097/00005768-199801000-00012

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Authors
MITTLEMAN, K. D., RICCI, M. R., & BAILEY, S. P.
Affiliations
Rutgers, The State University of New Jersey (US)
ORCID
RICCI, MATTHEW R.
Venue
Medicine & Science in Sports & Exercise
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1998-01
Volume
30
Issue
1
Pages
83-91
ISSN
0195-9131 (ISSN-L)
DOI
10.1097/00005768-199801000-00012
OpenAlex
W2017293576
Cited by
155
References
37
Citations by year
2026: 3 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 5 · 2021: 3 · 2020: 6 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 4 · 2012: 7
FWCI
3.68
Type
journal article
Language
en
Open access
closed
Locations
  • Medicine & Science in Sports & Exercise (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
branched-chain amino acids, heat stress, endurance exercise, time to exhaustion, exercise performance, plasma free tryptophan, plasma amino acids, plasma glucose, sex differences, thermoregulation, cardiovascular response
MeSH terms
Adolescent, Adult, Amino Acids, Branched-Chain, Ammonia, Blood Glucose, Exercise Test, Fatigue, Fatty Acids, Female, Humans, Male, Physical Endurance, Sex Factors, Tryptophan, Exercise, Heat Stress Disorders, Dietary Supplements

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