Cited by 209Lipid metabolism and disordersLipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

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Postprandial hyperlipidemia and remnant lipoproteins.

Havel, Richard J.·1994·Current Opinion in Lipidology

DOI 10.1097/00041433-199404000-00006

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Abstract

Improved methods for quantification of organ-specific contributions to postprandial hyperlipidemia indicate substantial increases in the concentration and altered properties of hepatogenous VLDL, in addition to accumulation of chylomicron remnants. Recent clinical studies support the hypothesis that small chylomicron remnants characterized by apolipoprotein (apo)B48 and VLDL remnants characterized by apolipoprotein B100 are atherogenic lipoproteins.

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Background
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BackgroundSelf-citation
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BackgroundInfluential
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Background
Particle size of apoB-48 carrying lipoproteins in remnant lipoproteins isolated from postprandial plasma.
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“After meal consumption, dietary FAs are esteriﬁed into triglycerides and incorporated into chylomicrons in the intestine (53).”
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“emnant lipoproteins, which are produced by ydrolysis of chylomicrons and very low-density ipoproteins, are thought to be atherogenic [1,2].”
Background
Chylomicron metabolism in an animal model for hyperlipoproteinemia type I
Savonen, R., Nordstoga, K., Christophersen, B. O., et al. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)33496-9 · Cited by 30

Authors: Havel, R. J.
Affiliations: University of California, San Francisco (US)
Corresponding author: Havel, Richard J.
Venue: Current Opinion in Lipidology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1994-04
Volume: 5
Issue: 2
Pages: 102-109
ISSN: 0957-9672 (ISSN-L)
DOI: 10.1097/00041433-199404000-00006
OpenAlex: W2046776466
Cited by: 209
References: 0
Citations by year: 2026: 2 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 15 · 2021: 1 · 2020: 5 · 2019: 1 · 2018: 2 · 2017: 5 · 2016: 7 · 2015: 4 · 2014: 3 · 2013: 6 · 2012: 2
FWCI: 10.75
Type: journal article
Language: en
Open access: closed
Locations: Current Opinion in Lipidology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Keywords: postprandial lipemia, remnant lipoproteins, chylomicron remnants, VLDL remnants, apolipoprotein B-48, apolipoprotein B-100, atherogenic lipoproteins, hepatic VLDL secretion
MeSH terms: Apolipoproteins B, Chylomicrons, Coronary Disease, Food, Humans, Hyperlipidemias, Lipoproteins, Lipoproteins, VLDL, Triglycerides, Apolipoprotein B-48, Apolipoprotein B-100

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Postprandial hyperlipidemia and remnant lipoproteins.

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