Detection, quantification, and characterization of potentially atherogenic triglyceride-rich remnant lipoproteins

Cohn, Jeffrey S.; Marcoux, Caroline; Davignon, Jean

doi:10.1161/01.atv.19.10.2474

Cited by 156Lipid metabolism and disordersLipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Detection, quantification, and characterization of potentially atherogenic triglyceride-rich remnant lipoproteins

Cohn, Jeffrey S., Marcoux, Caroline, Davignon, Jean·1999·Arteriosclerosis, Thrombosis, and Vascular Biology

DOI 10.1161/01.atv.19.10.2474

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Abstract

Abstract —Triglyceride-rich lipoprotein (TRL) remnants are formed in the circulation when apolipoprotein (apo) B-48–containing chylomicrons of intestinal origin or apoB-100–containing VLDL of hepatic origin are converted by lipoprotein lipase, and to a lesser extent by hepatic lipase, into smaller and more dense particles. Compared with their nascent precursors, TRL remnants are depleted of triglyceride, phospholipid, and C apolipoproteins and are enriched in cholesteryl esters and apoE. They can thus be identified, separated, and/or quantified in plasma according to their density, charge, size, specific lipid components, apolipoprotein composition, and/or apolipoprotein immunospecificity. Each of these approaches has contributed to our current understanding of the compositional characteristics of TRL remnants and their potential to promote atherosclerosis. An ongoing search is nevertheless under way for more accurate and clinically applicable remnant lipoprotein assays that will be able to better define coronary artery disease risk in patients with hypertriglyceridemia.

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Complete absence of lipolysis, i.e. complete lipoprotein lipase deficiency, results in extreme elevation of large nascent triglyceride-rich lipoproteins without any concomitant increase in remnants; pancreatitis rather than atherosclerotic cardiovascular disease is the major risk.
“The absence of lipolysis (i.e. complete LPL deficiency) results in the extreme elevation of large ‘nascent’ TRL without any concomitant increase in remnants;36,67,68 here, pancreatitis rather than ASCVD is the major risk.”
From Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society (2021) · cites this paper as [67]

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Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
The Metabolic Basis of Inherited Disease.
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-503_7 · Cited by 7,807 · see citing works
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setälä, K., Walsh, A., Verstuyft, J. G., Rubin, E. M., & Breslow, J. L. (1992) · Cell · doi:10.1016/0092-8674(92)90362-g · Cited by 2,263 · see citing works
Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E
Zhang, S. H., Reddick, R. L., Piedrahita, J. A., & Maeda, N. (1992) · Science · doi:10.1126/science.1411543 · Cited by 2,237 · see citing works
Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies
Hokanson, J. E., & Austin, M. A. (1996) · Journal of Cardiovascular Risk · doi:10.1097/00043798-199604000-00014 · Cited by 1,706 · see citing works
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.
Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L., & Ross, R. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.14.1.133 · Cited by 1,693 · see citing works
The Response-to-Retention Hypothesis of Early Atherogenesis
Williams, K. J., & Tabas, I. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.5.551 · Cited by 1,413 · see citing works
Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state
Patsch, J. R., Miesenböck, G., Hopferwieser, T., Mühlberger, V, Knapp, E., Dunn, J. K., Gotto, A. M., & Patsch, W. (1992) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.12.11.1336 · Cited by 1,122 · see citing works
The Role of Lipids and Lipoproteins in Atherosclerosis
Gofman, J. W., Lindgren, F. T., Elliott, H. A., Mantz, W., Hewitt, J. E., Strisower, B., Herring, V. V., & Lyon, T. P. (1950) · Science · doi:10.1126/science.111.2877.166 · Cited by 921 · see citing works
Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS)
Watts, G. F., Lewis, B., Lewis, E. S., Coltart, D. J., Smith, L. D. R., Swan, A. V., Brunt, J. N. H., & Mann, J. I. (1992) · The Lancet · doi:10.1016/0140-6736(92)90863-x · Cited by 843 · see citing works
RANDOMISED TRIAL OF FENTANYL ANAESTHESIA IN PRETERM BABIES UNDERGOING SURGERY: EFFECTS ON THE STRESS RESPONSE
Anand, K. J. S., Sippell, W. G., & Aynsley-Green, A. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91907-6 · Cited by 751 · see citing works
Epidemiology as a Guide to Clinical Decisions: The Association between Triglyceride and Coronary Heart Disease
Hulley, S. B., Rosenman, R. H., Bawol, R. D., & Brand, R. J. (1980) · New England Journal of Medicine · doi:10.1056/nejm198006193022503 · Cited by 702 · see citing works
Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study.
Brensike, J. F., Levy, R. I., Kelsey, S. F., Passamani, E. R., Richardson, J. M., Loh, I. K., Stone, N. J., Aldrich, R. F., Battaglini, J. W., & Moriarty, D. J. (1984) · Circulation · doi:10.1161/01.cir.69.2.313 · Cited by 668 · see citing works
Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression
Reddick, R. L., Zhang, S. H., & Maeda, N. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.14.1.141 · Cited by 633 · see citing works
Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.
Palinski, W., Hörkkö, S., Miller, E., Steinbrecher, U., Powell, H., Curtiss, L., & Witztum, J. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118853 · Cited by 593 · see citing works
Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease.
Groot, P. H. E., van Stiphout, W. A. H. J., Krauss, X. H., Jansen, H., van Tol, A., van Ramshorst, E., Chin-On, S., Albert Hofman, D., Cresswell, S. R., & Havekes, L. M. (1991) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.11.3.653 · Cited by 528 · see citing works
Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice
Praticò, D., Tangirala, R. K., Rader, D. J., Rokach, J., & FitzGerald, G. A. (1998) · Nature Medicine · doi:10.1038/2685 · Cited by 501 · see citing works
Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein
Brown, W. V., & Baginsky, M. L. (1972) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(72)80149-9 · Cited by 493 · see citing works
ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.
Palinski, W., Ord, V. A., Plump, A. S., Breslow, J. L., Steinberg, D. H., & Witztum, J. L. (1994) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.14.4.605 · Cited by 488 · see citing works
Postprandial lipoproteins and progression of coronary atherosclerosis
Karpe, F., Steiner, G. A., Uffelman, K. D., Olivecrona, T., & Hamsten, A. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90085-x · Cited by 486 · see citing works
Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.
Kowal, R. C., Herz, J., Weisgraber, K. H., Mahley, R. W., Brown, M. S., & Goldstein, J. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)87014-4 · Cited by 445 · see citing works
Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI: evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo
Ginsberg, H. N., Le, N. A., Goldberg, I. J., Gibson, J. C., Rubinstein, A., Wang-Iverson, P., Norum, R., & Brown, W. V. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112713 · Cited by 424 · see citing works
Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.
Weintraub, M. S., Eisenberg, S., & Breslow, J. L. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113243 · Cited by 418 · see citing works
Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels
Nakajima, K., SAITO, T., Tamura, A., Suzuki, M., Nakano, T., Adachi, M., Tanaka, A., Tada, N., Nakamura, H., Campos, E. M., et al. (1993) · Clinica Chimica Acta · doi:10.1016/0009-8981(93)90062-9 · Cited by 417 · see citing works
Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III.
Wang, C. S., McConathy, W. J., Kloer, H. U., & Alaupovic, P. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111711 · Cited by 414 · see citing works
Blocking and binding auto-antibody to intrinsic factor.
Bardhan, K. D., Hall, J. R., Spray, G. H., & Callender, S. T. (1968) · The Lancet · Cited by 401 · see citing works
Beneficial effects of colestipol-niacin therapy on the common carotid artery. Two- and four-year reduction of intima-media thickness measured by ultrasound.
Blankenhorn, D. H., Selzer, R. H., Crawford, D. W., Barth, J. D., Liu, C. R., Liu, C. H., Mack, W. J., & Alaupovic, P. (1993) · Circulation · doi:10.1161/01.cir.88.1.20 · Cited by 381 · see citing works
Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat.
Shelburne, F. A., Hanks, J., Meyers, W., & Quarfordt, S. H. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109710 · Cited by 358 · see citing works
Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events.
PHILLIPS, N. R., Waters, D. D., & Havel, R. J. (1993) · Circulation · doi:10.1161/01.cir.88.6.2762 · Cited by 345 · see citing works
Selective Retention of VLDL, IDL, and LDL in the Arterial Intima of Genetically Hyperlipidemic Rabbits In Vivo: Molecular Size as a Determinant of Fractional Loss From the Intima–Inner Media
Nordestgaard, B. G., Wootton, R., & Lewis, B. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.4.534 · Cited by 334 · see citing works
Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.
Weintraub, M. S., Zechner, R., Brown, A., Eisenberg, S., & Breslow, J. L. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113806 · Cited by 331 · see citing works
Reduction in Carotid Arterial Wall Thickness Using Lovastatin and Dietary Therapy
Hodis, H. N., Mack, W. J., LaBree, L., Selzer, R. H., Liu, C.-R., Liu, C.-H., Alaupovic, P., Kwong-Fu, H., & Azen, S. P. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-124-6-199603150-00002 · Cited by 323 · see citing works
Characterization of remnants produced during the metabolism of triglyceride-rich lipoproteins of blood plasma and intestinal lymph in the rat.
Mjøs, O. D., Færgeman, O., Hamilton, R. L., & Havel, R. J. (1975) · Journal of Clinical Investigation · doi:10.1172/jci108130 · Cited by 322 · see citing works
Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin.
Hodis, H. N., Mack, W. J., Azen, S. P., Alaupovic, P., Pogoda, J. M., LaBree, L., Hemphill, L., Kramsch, D. M., & Blankenhorn, D. H. (1994) · Circulation · doi:10.1161/01.cir.90.1.42 · Cited by 321 · see citing works
Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver.
Windler, E. E. T., & Havel, R. J. (1985) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34342-x · Cited by 314 · see citing works
Familial apolipoprotein E deficiency.
Schaefer, E. J., Gregg, R. E., Ghiselli, G., Forte, T. M., Ordovas, J. M., Zech, L. A., & Brewer, H. B. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112704 · Cited by 313 · see citing works
Prediction of angiographic change in native human coronary arteries and aortocoronary bypass grafts. Lipid and nonlipid factors.
Blankenhorn, D. H., Alaupovic, P., Wickham, E., Chin, H. P., & Azen, S. P. (1990) · Circulation · doi:10.1161/01.cir.81.2.470 · Cited by 278 · see citing works
Atherogenic Hyperlipoproteinemia: The Cellular and Molecular Biology of Plasma Lipoproteins Altered by Dietary Fat and Cholesterol
Mahley, R. W. (1982) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)31426-2 · Cited by 273 · see citing works
Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.
Hayek, T., Masucci-Magoulas, L., Jiang, X. L., Walsh, A., Rubin, E. M., Breslow, J. L., & Tall, A. R. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118255 · Cited by 266 · see citing works
Lipoprotein predictors of the severity of coronary artery disease in men and women.
Reardon, M. F., Nestel, P. J., Craig, I. H., & Harper, R. W. (1985) · Circulation · doi:10.1161/01.cir.71.5.881 · Cited by 266 · see citing works
Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramine and gemfibrozil.
Weintraub, M. S., Eisenberg, S., & Breslow, J. L. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112926 · Cited by 261 · see citing works
The biochemical, clinical, and genetic features of type III hyperlipoproteinemia.
MORGANROTH, J., LEVY, R. I., & FREDRICKSON, D. S. (1975) · Annals of Internal Medicine · doi:10.7326/0003-4819-82-2-158 · Cited by 260 · see citing works
Relationships between the responses of triglyceride-rich lipoproteins in blood plasma containing apolipoproteins B-48 and B-100 to a fat-containing meal in normolipidemic humans.
Schneeman, B. O., Kotite, L., Todd, K., & Havel, R. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.5.2069 · Cited by 255 · see citing works
Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2.
Sullivan, P. M., Mezdour, H., Quarfordt, S. H., & Maeda, N. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2673 · Cited by 254 · see citing works
INTERMEDIATE-DENSITY LIPOPROTEINS AND PROGRESSION OF CORONARY ARTERY DISEASE IN HYPERCHOLESTEROLAEMIC MEN
Krauss, R., Williams, P. T., Brensike, J. F., Detre, K. M., Lindgren, F. T., Kelsey, S. F., VRANIZAN, K. M., & Levy, R. (1987) · The Lancet · doi:10.1016/s0140-6736(87)92734-6 · Cited by 253 · see citing works
Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters
Cohn, J. S., Johnson, E. J., Millar, J. S., Cohn, S. D., Milne, R. W., Marcel, Y. L., Russell, R. M., & Schaefer, E. J. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)35345-1 · Cited by 248 · see citing works
Self-citation
Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease.
TATAMI, R., Mabuchi, H., Ueda, K., Ueda, R., Haba, T., KAMETANI, T., Ito, S., Koizumi, J., Ohta, M., Miyamoto, S., et al. (1981) · Circulation · doi:10.1161/01.cir.64.6.1174 · Cited by 246 · see citing works
Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells
Ji, Z. S., Brecht, W. J., Miranda, R. D., Hussain, M. M., Innerarity, T. L., & Mahley, R. W. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82186-x · Cited by 240 · see citing works
Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics.
Hegele, R. A., Little, J. A., Vézina, C., Maguire, G. F., Tu, L., Wolever, T. S., Jenkins, D. J., & Connelly, P. W. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.5.720 · Cited by 239 · see citing works
Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia
Pagnan, A., Havel, R. J., Kane, J. P., & Kotite, L. (1977) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41603-7 · Cited by 236 · see citing works
A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study.
Parra, H. J., Arveiler, D., Evans, A. E., Cambou, J., Amouyel, P., Bingham, A., McMaster, D., Schaffer, P., DOUSTE‐BLAZY, P., & Luc, G. (1992) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.12.6.701 · Cited by 232 · see citing works
Metabolism of triglyceride-rich lipoproteins during alimentary lipemia.
Karpe, F., Steiner, G. A., Olivecrona, T., Carlson, L. A., & Hamsten, A. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116293 · Cited by 231 · see citing works
Postprandial lipemia, fenofibrate and coronary artery disease
Simpson, H., Williamson, C., Olivecrona, T., Pringle, S., MacLean, J. A., Lorimer, A. R., Bonnefous, F., Bogaievsky, Y., Packard, C. J., & Shepherd, J. (1990) · Atherosclerosis · doi:10.1016/0021-9150(90)90111-u · Cited by 229 · see citing works
Atherogenicity of Triglyceride-Rich Lipoproteins
Krauss, R. M. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00032-0 · Cited by 227 · see citing works
Catabolism of Very Low Density Lipoprotein B Apoprotein in Man
Reardon, M., Fidge, N., & Nestel, P. J. (1978) · Journal of Clinical Investigation · doi:10.1172/jci108999 · Cited by 224 · see citing works
Clearance of chylomicron remnants in normolipidaemic patients with coronary artery disease: case control study over three years
Weintraub, M. S., Grosskopf, I., Rassin, T., Miller, H. I., Charach, G., Rotmensch, H. H., Liron, M., Rubinstein, A., & Iaina, A. (1996) · BMJ · doi:10.1136/bmj.312.7036.935 · Cited by 216 · see citing works
Postprandial hyperlipidemia and remnant lipoproteins.
Havel, R. J. (1994) · Current Opinion in Lipidology · doi:10.1097/00041433-199404000-00006 · Cited by 209 · see citing works
Apolipoprotein E and atherosclerosis: insight from animal and human studies
Davignon, J., Cohn, J. S., Mabile, L., & Bernier, L. (1999) · Clinica Chimica Acta · doi:10.1016/s0009-8981(99)00097-2 · Cited by 208 · see citing works
Self-citation
Chylomicrons and chylomicron remnants in coronary artery disease: a case-control study
Simons, L. A., Dwyer, T., Simons, J. A., Bernstein, L., Mock, P. A., Pooma, N. S., Balasubramaniam, S., Baron, D., Branson, J., Morgan, J., et al. (1987) · Atherosclerosis · doi:10.1016/0021-9150(87)90020-7 · Cited by 205 · see citing works
PLASMA-TRIGLYCERIDES IN REGULATION OF H.D.L.-CHOLESTEROL LEVELS
Schaefer, E. J., Anderson, D. W., Brewer, H. B., Levy, R. I., Danner, R., & Blackwelder, W. C. (1978) · The Lancet · doi:10.1016/s0140-6736(78)91863-9 · Cited by 196 · see citing works
Plasma apolipoprotein changes in the triglyceride-rich lipoprotein fraction of human subjects fed a fat-rich meal.
Cohn, J. S., McNamara, J. R., Cohn, S. D., Ordovas, J. M., & Schaefer, E. J. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38485-6 · Cited by 195 · see citing works
Self-citation
Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E.
Ebara, T., Ramakrishnan, R., Steiner, G. A., & Shachter, N. S. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119456 · Cited by 191 · see citing works
Association of Remnant Lipoprotein Levels With Impairment of Endothelium-Dependent Vasomotor Function in Human Coronary Arteries
Kugiyama, K., Doi, H., Motoyama, T., Soejima, H., Misumi, K., Kawano, H., Nakagawa, O., Yoshimura, M., Ogawa, H., Matsumura, T., et al. (1998) · Circulation · doi:10.1161/01.cir.97.25.2519 · Cited by 187 · see citing works
Oxidized lipids in the diet are a source of oxidized lipid in chylomicrons of human serum.
Staprãns, I., Rapp, J. H., Pan, X.-M., Kim, K. Y., & Feingold, K. R. (1994) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.14.12.1900 · Cited by 186 · see citing works
Properties of an apolipoprotein E-enriched fraction of triglyceride-rich lipoproteins isolated from human blood plasma with a monoclonal antibody to apolipoprotein B-100.
Campos, E. M., Nakajima, K., Tanaka, A., & Havel, R. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41527-5 · Cited by 185 · see citing works
The Role of Triglyceride-Rich Lipoprotein Families in the Progression of Atherosclerotic Lesions as Determined by Sequential Coronary Angiography From a Controlled Clinical Trial
Alaupovic, P., Mack, W. J., Knight‐Gibson, C., & Hodis, H. N. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.4.715 · Cited by 184 · see citing works
Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency.
Havel, R. J., Kotite, L., Vigne, J. L., Kane, J. P., Tun, P., PHILLIPS, N. R., & Chen, G. C. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109988 · Cited by 184 · see citing works
Modulation of Lipoprotein B Binding to the LDL Receptor by Exogenous Lipids and Apolipoproteins CI, CII, CIII, and E
Barthelemy-Clavey, V., Lestavel-Delattre, S., Copin, C., Bard, J., & Fruchart, J. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.7.963 · Cited by 178 · see citing works
Type III Hyperlipoproteinemia: An Analysis of Two Contemporary Definitions
Fredrickson, D. S., MORGANROTH, J., & LEVY, R. I. (1975) · Annals of Internal Medicine · doi:10.7326/0003-4819-82-2-150 · Cited by 177 · see citing works
Apolipoprotein C-II and C-III levels in hyperlipoproteinemia
Schonfeld, G., George, P. K., Miller, J. P., Reilly, P., & Witztum, J. L. (1979) · Metabolism · doi:10.1016/0026-0495(79)90004-0 · Cited by 176 · see citing works
Radioimmunoassay studies of human apolipoprotein E.
Blum, C. B., Aron, L., & Sciacca, R. R. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109975 · Cited by 176 · see citing works
Lipoprotein Subclasses in the Monitored Atherosclerosis Regression Study (MARS)
Mack, W. J., Krauss, R. M., & Hodis, H. N. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.5.697 · Cited by 173 · see citing works
Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)
Hazzard, W. R., & Bierman, E. L. (1976) · Metabolism · doi:10.1016/0026-0495(76)90149-9 · Cited by 169 · see citing works
Effect of serum and C‐apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase
Kinnunen, P. K. J., & Ehnholm, C. (1976) · FEBS Letters · doi:10.1016/0014-5793(76)80145-7 · Cited by 166 · see citing works
Influx in vivo of low density, intermediate density, and very low density lipoproteins into aortic intimas of genetically hyperlipidemic rabbits. Roles of plasma concentrations, extent of aortic lesion, and lipoprotein particle size as determinants.
Nordestgaard, B. G., Tybjaerg-Hansen, A., & Lewis, B. (1992) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.12.1.6 · Cited by 159 · see citing works
Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits
Nordestgaard, B. G., & Zilversmit, D. B. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38428-5 · Cited by 156 · see citing works
Intermediate-Density Lipoproteins and Progression of Carotid Arterial Wall Intima-Media Thickness
Hodis, H. N., Mack, W. J., Dunn, M. E., Liu, C., Ci-hua, L., Selzer, R. H., & Krauss, R. M. (1997) · Circulation · doi:10.1161/01.cir.95.8.2022 · Cited by 155 · see citing works
Postprandial plasma vitamin A metabolism in humans: A reassessment of the use of plasma retinyl esters as markers for intestinally derived chylomicrons and their remnants
Krasinski, S. D., Cohn, J. S., Russell, R. M., & Schaefer, E. J. (1990) · Metabolism · doi:10.1016/0026-0495(90)90249-c · Cited by 151 · see citing works
Self-citation
Independent associations between plasma lipoprotein subfraction levels and the course of coronary artery disease in the St. Thomas' Atherosclerosis Regression Study (STARS)
Watts, G. F., Mandalia, S., Brunt, J. N. H., Slavin, B. M., COLTART, D. J., & Lewis, B. (1993) · Metabolism · doi:10.1016/0026-0495(93)90199-x · Cited by 146 · see citing works
Association of Postprandial Triglyceride and Retinyl Palmitate Responses With Asymptomatic Carotid Artery Atherosclerosis in Middle-aged Men and Women
Sharrett, A. R., Chambless, L. E., HEISS, G. M., Paton, C. C., & Patsch, W. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.12.2122 · Cited by 143 · see citing works
Quantification of postprandial triglyceride-rich lipoproteins in healthy men by retinyl ester labeling and simultaneous measurement of apolipoproteins B-48 and B-100
Karpe, F., Bell, M., Björkegren, J., & Hamsten, A. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.2.199 · Cited by 143 · see citing works
A Mouse Model with Features of Familial Combined Hyperlipidemia
Masucci-Magoulas, L., Goldberg, I. J., Bisgaier, C. L., Serajuddin, H., Francone, O. L., Breslow, J. L., & Tall, A. R. (1997) · Science · doi:10.1126/science.275.5298.391 · Cited by 141 · see citing works
Quantitative determination of human apolipoprotein Cc-III by electroimmunoassay
Curry, M. D., McConathy, W. J., Fesmire, J. D., & Alaupovic, P. (1980) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(80)90016-8 · Cited by 140 · see citing works
Role of apolipoprotein E in the lipolytic conversion of beta-very low density lipoproteins to low density lipoproteins in type III hyperlipoproteinemia.
Ehnholm, C., Mahley, R. W., Chappell, D. A., Weisgraber, K. H., Ludwig, E. H., & Witztum, J. L. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.17.5566 · Cited by 137 · see citing works
Plasma clearance of chylomicrons labeled with retinyl palmitate in healthy human subjects.
Berr, F., & Kern, F. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37744-0 · Cited by 132 · see citing works
Association of Postprandial Triglyceride and Retinyl Palmitate Responses With Newly Diagnosed Exercise-Induced Myocardial Ischemia in Middle-Aged Men and Women
Ginsberg, H. N., Jones, J., Blaner, W. S., Thomas, A., Karmally, W., Fields, L., Blood, D. K., & Begg, M. D. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.11.1829 · Cited by 128 · see citing works
Atherosclerosis and arterial influx of lipoproteins
Nordestgaard, B. G., & Nielsen, L. B. (1994) · Current Opinion in Lipidology · doi:10.1097/00041433-199408000-00002 · Cited by 126 · see citing works
Relationship between apolipoproteins and chemical components of lipoproteins in survivors of myocardial infarction
Avogaro, P., Bon, G. B., Cazzolato, G., & Rorai, E. (1980) · Atherosclerosis · doi:10.1016/0021-9150(80)90094-5 · Cited by 125 · see citing works
Plasma apolipoprotein A-I, A-II, B, E and C-III containing particles in men with premature coronary artery disease
GENESTJR, J., Bard, J., Fruchart, J., Ordovás, J. M., WILSON, P., & Schaefer, E. J. (1991) · Atherosclerosis · doi:10.1016/0021-9150(91)90109-g · Cited by 122 · see citing works
Postprandial Triglyceride Response in Young Adult Men and Familial Risk for Coronary Atherosclerosis
Uiterwaal, C. S. P. M., Grobbee, D. E., Witteman, J. C. M., van Stiphout, W.-A. H. J., Krauss, X. H., Havekes, L. M., de Bruijn, A. M., van Tol, A., & Albert Hofman, D. (1994) · Annals of Internal Medicine · doi:10.7326/0003-4819-121-8-199410150-00004 · Cited by 121 · see citing works
The association of increased levels of intermediate-density lipoproteins with smoking and with coronary artery disease.
GSteiner, LSchwartz, SShumak, & MPoapst (1987) · Circulation · Cited by 119 · see citing works
Biological variability in concentrations of serum lipids: sources of variation among results from published studies and composite predicted values
Smith, S. J., Cooper, G. R., Myers, G. L., & Sampson, E. J. (1993) · Clinical Chemistry · doi:10.1093/clinchem/39.6.1012 · Cited by 118 · see citing works
Apolipoprotein E secretion by macrophages: its potential physiological functions
Mazzone, T. (1996) · Current Opinion in Lipidology · doi:10.1097/00041433-199610000-00008 · Cited by 116 · see citing works
Triglycerides: a risk factor for coronary heart disease
Davignon, J., & Cohn, J. S. (1996) · Atherosclerosis · doi:10.1016/0021-9150(96)05858-3 · Cited by 115 · see citing works
Self-citation
Apolipoproteins C–III and E in apoB- and non-apoB-containing lipoproteins in two populations at contrasting risk for myocardial infarction: the ECTIM study. Etude Cas Temoins sur 'Infarctus du Myocarde
Luc, G., Fievet, C., Arveiler, D., Evans, A. E., Bard, J. M., Cambien, F., Fruchart, J. C., & Ducimetiere, P. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37594-5 · Cited by 114 · see citing works
Plasma lipoprotein distribution of apoC-III in normolipidemic and hypertriglyceridemic subjects: comparison of the apoC-III to apoE ratio in different lipoprotein fractions
Fredenrich, A., Giroux, L.-M., Tremblay, M., Krimbou, L., Davignon, J., & Cohn, J. S. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37424-1 · Cited by 114 · see citing works
Self-citation
Increased frequency of lipoprotein disorders similar to type iii hyperlipoproteinemia in survivors of myocardial infarction in Japan
Kameda, K., MATSUZAWA, Y., KUBO, M., Ishikawa, K., Maejima, I., Yamamura, T., Yamamoto, A. C., & Tarui, S. (1984) · Atherosclerosis · doi:10.1016/0021-9150(84)90171-0 · Cited by 113 · see citing works
Evaluation of an immunoseparation method for quantitative measurement of remnant-like particle-cholesterol in serum and plasma
Leary, E. T., Wang, T., Baker, D. J., Cilla, D. D., Zhong, J., Warnick, G. R., Nakajima, K., & Havel, R. J. (1998) · Clinical Chemistry · doi:10.1093/clinchem/44.12.2490 · Cited by 110 · see citing works
Triglyceride
Gotto, A. M. (1998) · Circulation · doi:10.1161/01.cir.97.11.1027 · Cited by 109 · see citing works
Apolipoprotein E-enriched lipoprotein subclasses in normolipidemic subjects.
Gibson, J. C., Rubinstein, A., Bukberg, P. R., & Brown, W. V. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37934-7 · Cited by 108 · see citing works
Antiatherosclerotic and Antioxidative Effects of Captopril in Apolipoprotein E-Deficient Mice
Hayek, T., Attias, J., Smith, J. D., Breslow, J. L., & Keidar, S. (1998) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199804000-00011 · Cited by 107 · see citing works
Remnants of lipoproteins of intestinal and hepatic origin in familial dysbetalipoproteinemia.
Kane, J. P., Chen, G. C., Hamilton, R. L., Hardman, D. A., Malloy, M. J., & Havel, R. J. (1983) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc. · doi:10.1161/01.atv.3.1.47 · Cited by 106 · see citing works
Oxidized Lipids in the Diet Accelerate the Development of Fatty Streaks in Cholesterol-Fed Rabbits
Staprãns, I., Rapp, J. H., Pan, X.-M., Hardman, D. A., & Feingold, K. R. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.4.533 · Cited by 105 · see citing works
Remnant lipoprotein cholesterol and triglyceride reference ranges from the Framingham Heart Study
McNamara, J. R., Shah, P. K., Nakajima, K., Cupples, L. A., Wilson, P. W. F., Ordovás, J. M., & Schaefer, E. J. (1998) · Clinical Chemistry · doi:10.1093/clinchem/44.6.1224 · Cited by 105 · see citing works
Lipoprotein lipase increases lipoprotein binding to the artery wall and increases endothelial layer permeability by formation of lipolysis products.
Rutledge, J. C., Woo, M. M., Rezai, A. A., Curtiss, L. K., & Goldberg, I. J. (1997) · Circulation Research · doi:10.1161/01.res.80.6.819 · Cited by 101 · see citing works
Evidence for the distribution of apolipoprotein E between lipoprotein classes in human normocholesterolemic plasma and for the origin of unassociated apolipoprotein E (Lp-E).
Castro, G., & Fielding, C. J. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37844-5 · Cited by 98 · see citing works
Plasma Concentration of Apolipoprotein E in Intermediate-Sized Remnant-Like Lipoproteins in Normolipidemic and Hyperlipidemic Subjects
Cohn, J. S., Tremblay, M., Amiot, M., Bouthillier, D., Roy, M., Genest, J. J., & Davignon, J. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.1.149 · Cited by 96 · see citing works
Self-citation
Lipolysis of triglyceride-rich lipoproteins activates coagulant factor XII: A study in familial lipoprotein-lipase deficiency
Mitropoulos, K. A., Miller, G. J., Watts, G. F., & Durrington, P. N. (1992) · Atherosclerosis · doi:10.1016/0021-9150(92)90015-9 · Cited by 96 · see citing works
Remnant-like Particle Cholesterol Levels in Patients with Dysbetalipoproteinemia or Coronary Artery Disease
Devaraj, S., Vega, G., Lange, R., Grundy, S. M., & Jialal, I. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(98)00089-8 · Cited by 94 · see citing works
Apolipoprotein composition as the basis for classifying plasma lipoproteins. Characterization of ApoA- and ApoB-containing lipoprotein families
Alaupovic, P. (1991) · Progress in Lipid Research · doi:10.1016/0163-7827(91)90008-s · Cited by 94 · see citing works
Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis
Hofker, M. H., van Vlijmen, B. J. M., & Havekes, L. M. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00266-9 · Cited by 91 · see citing works
Isolation and properties of nascent lipoproteins from highly purified rat hepatocytic Golgi fractions
Hamilton, R., Moorehouse, A., & Havel, R. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42077-2 · Cited by 90 · see citing works
Apolipoprotein E: genetic variants provide insights into its structure and function
Mahley, R. W., Innerarity, T. L., Rail, S. C., Weisgraber, K. H., & Taylor, J. M. (1990) · Current Opinion in Lipidology · doi:10.1097/00041433-199004000-00002 · Cited by 88 · see citing works
Lipoprotein and receptor interactions in vivo
Herz, J., & Willnow, T. E. (1995) · Current Opinion in Lipidology · doi:10.1097/00041433-199504000-00007 · Cited by 88 · see citing works
McCollum Award Lecture, 1993: Triglyceride-rich lipoproteins and atherosclerosis—new perspectives
Havel, R. J. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.4.795 · Cited by 87 · see citing works
Presence of multiple subpopulations of lipoproteins of intermediate density in normal subjects
Musliner, T. A., Giotas, C., & Krauss, R. M. (1986) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc. · doi:10.1161/01.atv.6.1.79 · Cited by 87 · see citing works
Quantitation of human apolipoprotein C-III and its subspecie by radioimmunoassay and analytical isoelectric focusing: abnormal plasma triglyceride-rich lipoprotein apolipoprotein C-III subspecie concentrations in hypertriglyceridemia.
Kashyap, M. L., Srivastava, L., Hynd, B. A., Gartside, P. S., & Perisutti, G. (1981) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37352-1 · Cited by 84 · see citing works
Effect of heparin-induced lipolysis on the distribution of apolipoprotein e among lipoprotein subclasses. Studies with patients deficient in hepatic triglyceride lipase and lipoprotein lipase.
Rubinstein, A., Gibson, J. C., Paterniti, J. R., Kakis, G., Little, A., Ginsberg, H. N., & Brown, W. V. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111751 · Cited by 83 · see citing works
Characterization of monoclonal antibodies against human apolipoprotein E.
Milne, R. W., DOUSTE‐BLAZY, P., Marcel, Y. L., & Retegui, L. A. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110225 · Cited by 80 · see citing works
The effect of oxidized lipids in the diet on serum lipoprotein peroxides in control and diabetic rats.
Staprãns, I., Rapp, J. H., Pan, X.-M., & Kr, F. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116632 · Cited by 80 · see citing works
Cholesterol efflux from macrophages and other cells
von Eckardstein, A. (1996) · Current Opinion in Lipidology · doi:10.1097/00041433-199610000-00009 · Cited by 77 · see citing works
Uptake of Remnant Like Particles (RLP) in Diabetic Patients from Mouse Peritoneal Macrophages
Tomono, S., Kawazu, S., Kato, N., Ono, T., Ishii, C., Ito, Y., Shimizu, M., Shimoyama, M., Nakano, T., & Nakajima, K. (1994) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.1.98 · Cited by 76 · see citing works
Quantification of apolipoproteins B-100, B-48, and E in human triglyceride-rich lipoproteins
Kotite, L., Bergeron, N., & Havel, R. J. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40071-9 · Cited by 75 · see citing works
Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias.
Huff, M. W., Evans, A. J., Sawyez, C. G., Wolfe, B. M. J., & Nestel, P. J. (1991) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.11.2.221 · Cited by 74 · see citing works
Lipolytic surface remnants of triglyceride-rich lipoproteins are cytotoxic to macrophages but not in the presence of high density lipoprotein. A possible mechanism of atherogenesis?
Chung, B. H., Segrest, J. P., Smith, K. A., Griffin, F. M., & Brouillette, C. G. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114024 · Cited by 73 · see citing works
David Rubinstein Memorial Lecture: The biochemical and clinical significance of the interrelationship between very low density and high density lipoproteins
Alaupovic, P. (1981) · Canadian Journal of Biochemistry · doi:10.1139/o81-079 · Cited by 69 · see citing works
Cellular binding site and membrane binding proteins for triglyceride-rich lipoproteins in human monocyte-macrophages and THP-1 monocytic cells.
Gianturco, S. H., Ramprasad, M. P., Lin, A. H., Song, R., & Bradley, W. A. (1994) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41165-4 · Cited by 64 · see citing works
Epidemiological aspects of high density lipoprotein cholesterol1Presented at the 68th meeting of the European Atherosclerosis Society, Brugge, 8–10 May, 1997.1
Backer, G. D., Bacquer, D. D., & Kornitzer, M. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00310-9 · Cited by 62 · see citing works
Characterization of remnant-like particles isolated by immunoaffinity gel from the plasma of type III and type IV hyperlipoproteinemic patients
Marcoux, C., Tremblay, M., Nakajima, K., Davignon, J., & Cohn, J. S. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32142-8 · Cited by 61 · see citing works
Self-citation
Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms
Evans, A. J., Sawyez, C. G., Wolfe, B. M. J., Connelly, P. W., Maguire, G., & Huff, M. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39692-9 · Cited by 61 · see citing works
Type III dyslipoproteinemia in patients heterozygous for familial hypercholesterolemia and apolipoprotein E2. Evidence for a gene-gene interaction.
Hopkins, P. N., Wu, L., Schumacher, M. C., Emi, M., Hegele, R. A., Hunt, S. C., Lalouel, J.-M., & Williams, R. R. (1991) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.11.5.1137 · Cited by 60 · see citing works
Apolipoprotein B synthesis in humans: Liver synthesizes only apolipoprotein B-100
Edge, S. B., Hoeg, J. M., Schneider, P. D., & Brewer, H. B. (1985) · Metabolism · doi:10.1016/0026-0495(85)90022-8 · Cited by 59 · see citing works
Uptake of type III hypertriglyceridemic VLDL by macrophages is enhanced by oxidation, especially after remnant formation
Whitman, S. C., Miller, D. B., Wolfe, B. M., Hegele, R. A., & Huff, M. W. (1997) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.17.9.1707 · Cited by 59 · see citing works
Plasma remnant-like particle lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects
Marcoux, C., Tremblay, M., Fredenrich, A., Jacques, H., Krimbou, L., Nakajima, K., Davignon, J., & Cohn, J. S. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00042-2 · Cited by 57 · see citing works
Self-citation
Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.
Alaupovic, P., Knight‐Gibson, C., Wang, C., Downs, D., Koren, E., Brewer, H., & Gregg, R. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42239-4 · Cited by 57 · see citing works
Triglyceride enriched lipoprotein particles correlate with the severity of coronary artery disease
Koren, E., Corder, C. N., Mueller, G., Centurion, H., Hallum, G., Fesmire, J., McConathy, W. D., & Alaupovic, P. (1996) · Atherosclerosis · doi:10.1016/0021-9150(95)05791-9 · Cited by 56 · see citing works
Quantitation of apolipoprotein B-48 in triacylglycerol-rich lipoproteins by a specific enzyme-linked immunosorbent assay
Lovegrove, J. A., Isherwood, S. G., Jackson, K. G., Williams, C. M., & GOULD, B. J. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(96)00039-2 · Cited by 54 · see citing works
Measurement of postprandial remnant-like particles (RLPs) following a fat-loading test
Tanaka, A., Tomie, N., Nakano, T., Nakajima, K., Yui, K., Tamura, M., & Numano, F. (1998) · Clinica Chimica Acta · doi:10.1016/s0009-8981(98)00073-4 · Cited by 54 · see citing works
Apolipoprotein E2 Transgenic Rabbits
Huang, Y., Schwendner, S. W., Rall, S. C., Sanan, D. A., & Mahley, R. W. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.36.22685 · Cited by 52 · see citing works
Oxidized type IV hypertriglyceridemic VLDL-remnants cause greater macrophage cholesteryl ester accumulation than oxidized LDL
Whitman, S. C., Sawyez, C. G., Miller, D. B., Wolfe, B. M. J., & Huff, M. W. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)33868-2 · Cited by 51 · see citing works
Effects of Diet on Apoprotein E Levels and on the Apoprotein E Subspecies in Human Plasma Lipoproteins*
Falko, J. M., Schonfeld, G., Witztum, J. L., Kolar, J. B., Weidman, S. W., & Steelman, R. J. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-50-3-521 · Cited by 46 · see citing works
A New Approach for the Detection of Type III Hyperlipoproteinemia by RLP-Cholesterol Assay
Nakajima, K., SAITO, T., Tamura, A., Suzuki, M., Nakano, T., Adachi, M., Tanaka, A., Tada, N., Nakamura, H., & Murase, T. (1994) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.1.30 · Cited by 45 · see citing works
The investigation of “mid-band” lipoproteins using polyacrylamide gel electrophoresis
Mead, M., & Dangerfield, W. G. (1974) · Clinica Chimica Acta · doi:10.1016/0009-8981(74)90027-8 · Cited by 43 · see citing works
Relative contribution of triglyceride-rich lipoprotein particle size and number to plasma triglyceride concentration.
Poapst, M. E., Reardon, M., & Steiner, G. A. (1985) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.5.4.381 · Cited by 43 · see citing works
Remnant-like lipoproteins stimulate whole blood platelet aggregation in vitro
Knöfler, R., Nakano, T., Nakajima, K., Takada, Y., & Takada, A. (1995) · Thrombosis Research · doi:10.1016/0049-3848(95)00044-5 · Cited by 41 · see citing works
The possible role of remnant-like particles as a risk factor for sudden cardiac death
Takeichi, S., Nakajima, Y., Osawa, M., Yukawa, N., Saito, T., Seto, Y., Nakano, T., Adachi, M., Jitsukata, K., Horiuchi, K., et al. (1997) · International Journal of Legal Medicine · doi:10.1007/s004140050070 · Cited by 41 · see citing works
A change in apolipoprotein B expression is required for the binding of apolipoprotein E to very low density lipoprotein.
Ishikawa, Y., Fielding, C. J., & Fielding, P. E. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69131-8 · Cited by 40 · see citing works
Resistance of a very low density lipoprotein subpopulation from familial dysbetalipoproteinemia to in vitro lipolytic conversion to the low density lipoprotein density fraction.
Chung, B. H., & Segrest, J. P. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37898-6 · Cited by 40 · see citing works
Plasma lipoprotein distribution of apolipoprotein E in familial hypercholesterolemia.
Gibson, J. C., Goldberg, R. B., Rubinstein, A., Ginsberg, H. N., Brown, W. V., Baker, S. G., Joffe, B. I., & Seftel, H. C. (1987) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.7.4.401 · Cited by 40 · see citing works
Cholesteryl ester accumulation in mouse peritoneal macrophages induced by β-migrating very low density lipoproteins from patients with atypical dysbetalipoproteinemia
Bersot, T. P., Innerarity, T. L., Mahley, R. W., & Havel, R. J. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111026 · Cited by 40 · see citing works
Characteristics of coronary artery disease and lipoprotein abnormalities in patients with heterozygous familial hypercholesterolemia associated with diabetes mellitus or impaired glucose tolerance
Yanagi, K., Yamashita, S., Kihara, S., Nakamura, T., Nozaki, S., Nagai, Y., Funahashi, T., Kameda-Takemura, K., Ueyama, Y., Jiao, S., et al. (1997) · Atherosclerosis · doi:10.1016/s0021-9150(97)00076-2 · Cited by 31 · see citing works
Quantitative Determination of Different Apolipoprotein B Containing Lipoproteins by an Enzyme Linked Immunosorbent Assay: Apo B with Apo C-III and Apo B with Apo E
Kandoussi, A., Cachera, C., Parsy, D., Bard, J., Fruchart, J., & Tacquet, A. (1991) · Journal of Immunoassay · doi:10.1080/01971529108055075 · Cited by 31 · see citing works
An increase of serum remnant-like particles in non-insulin-dependent diabetic patients with microalbuminuria
Shimizu, H., Mori, M., & SAITO, T. (1993) · Clinica Chimica Acta · doi:10.1016/0009-8981(93)90033-z · Cited by 31 · see citing works
Serum lipid and lipoprotein levels in Japanese patients with familial hypercholesterolemia
Mabuchi, H., Tatami, R., Ueda, K., Ueda, R., Haba, T., KAMETANI, T., Watanabe, A., WAKASUGI, T., Ito, S., Koizumi, J., et al. (1979) · Atherosclerosis · doi:10.1016/0021-9150(79)90009-1 · Cited by 31 · see citing works
Quick method of determining lipoproteins, including those of intermediate density, in serum.
Fontanals-Ferrer, N., Serrat-Serrat, J., Sorribas-Vivas, A., Gonzalez-Garcia, C., González‐Sastre, F., & Gómez-Gerique, J. A. (1988) · Clinical Chemistry · doi:10.1093/clinchem/34.9.1749 · Cited by 28 · see citing works
Inherited Disorders of Lipid Transport
Schonfeld, G. (1990) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30323-2 · Cited by 28 · see citing works
Remnant-Like Particle Cholesterol May Indicate Atherogenic Risk in Patients on Chronic Hemodialysis
Oda, H., Yorioka, N., Okushin, S., Nishida, Y., Kushihata, S., Ito, T., & Yamakido, M. (2008) · The Nephron journals/Nephron journals · doi:10.1159/000190133 · Cited by 27 · see citing works
Triglyceride-rich lipoproteins and their role in atherogenesis
Gianturco, S. H., & Bradley, W. A. (1991) · Current Opinion in Lipidology · doi:10.1097/00041433-199110000-00009 · Cited by 27 · see citing works
Remnant‐like Particles and Restenosis of Coronary Arteries after PTCA
Tanaka, A., Ejiri, N., Fujinuma, Y., Yui, K., Tamura, M., Nakajima, K., MOROHOSHI, M., Fujisawa, K., UCHIMURA, I., & Numano, F. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb17369.x · Cited by 22 · see citing works
Selective isolation of human plasma low-density lipoprotein particles containing apolipoproteins B and E by use of a monoclonal antibody to apolipoprotein B
Koren, E., Alaupovic, P., Lee, D. M., Dashti, N., Kloer, H. U., & Wen, G. (1987) · Biochemistry · doi:10.1021/bi00384a012 · Cited by 22 · see citing works
Plasma lipoproteins in familial dysbetalipoproteinemia associated with apolipoproteins E2(Arg158-->Cys), E3-Leiden, and E2(Lys146-->Gln), and effects of treatment with simvastatin.
Zhao, S. P., Smelt, A. H., Van den Maagdenberg, A. M., Van Tol, A., Vroom, T. F., Gevers Leuven, J. A., Frants, R. R., Havekes, L. M., Van der Laarse, A., & Van 't Hooft, F. M. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.14.11.1705 · Cited by 22 · see citing works
Comparison of four procedures for separating apolipoprotein A- and apolipoprotein B-containing lipoproteins in plasma.
Puchois, P., Luley, C., & Alaupovic, P. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.9.1597 · Cited by 21 · see citing works
Uptake by J774 Macrophages of Very-Low-Density Lipoproteins Isolated From ApoE-Deficient Mice Is Mediated by a Distinct Receptor and Stimulated by Lipoprotein Lipase
Hendriks, W. L., Beer, F. V. D. S.-D., van Vlijmen, B. J. M., van Vark, L. C., Hofker, M. H., & Havekes, L. M. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.3.498 · Cited by 20 · see citing works
Beta-VLDL in hepatic lipase deficiency induces apoE-mediated cholesterol ester accumulation in macrophages.
Huff, M. W., Sawyez, C. G., Connelly, P. W., Maguire, G. F., Little, J. A., & Hegele, R. A. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.9.1282 · Cited by 19 · see citing works
The Very Low- and Intermediate-Density Lipoprotein Fraction Isolated from Apolipoprotein E-Knockout Mice Transforms Macrophages to Foam Cells through an Apolipoprotein E-Independent Pathway
Hakamata, H., Sakaguchi, H., Zhang, C., Sakashita, N., Suzuki, H., Miyazaki, A., Takeya, M., Takahashi, K., Kitamura, N., & Horiuchi, S. (1998) · Biochemistry · doi:10.1021/bi980762v · Cited by 19 · see citing works
Human THP-1 monocyte-macrophage membrane binding proteins and distinct receptor(s) for triglyceride-rich lipoproteins
Ramprasad, M. P., Li, R., Bradley, W. A., & Gianturco, S. H. (1995) · Biochemistry · doi:10.1021/bi00028a023 · Cited by 19 · see citing works
Isolation and characterization of human Lp-B lipoprotein containing apolipoprotein B as the sole apolipoprotein
Bard, J., Candelier, L., Agnani, G., Barthelemy-Clavey, V., Torpier, G., Steinmetz, A., & Fruchart, J. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90191-j · Cited by 19 · see citing works
The in vitro effects of chylomicron remnant and very low density lipoprotein remnant on platelet aggregation in blood obtained from healthy persons
Mochizuki, M., Takada, Y., Urano, T., Nagai, N., Nakano, T., Nakajima, K., & Takada, A. (1996) · Thrombosis Research · doi:10.1016/0049-3848(96)00033-3 · Cited by 17 · see citing works
Prevalence and association of atherosclerosis at three different arterial sites in patients with type III hyperlipoproteinemia
Dobmeyer, J., Lohrmann, J., & Feussner, G. (1996) · Atherosclerosis · doi:10.1016/0021-9150(95)05633-5 · Cited by 17 · see citing works
High postprandial plasma remnant-like particles-cholesterol in patients with coronary artery diseases on chronic maintenance hemodialysis.
Sekihara, T., Nakano, T., & Nakajima, K. (1996) · PubMed · Cited by 16 · see citing works
ApoB-Containing Lipoprotein Particles as Risk Factors for Coronary Artery Disease
Alaupovic, P., Blackenhorn, D. H., Knight‐Gibson, C., Tavella, M. J., Bard, J., Shafer, D., Lee, E. T., & Brasuell, J. (1990) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-5904-3_36 · Cited by 15 · see citing works
Postprandial Hyperlipemia and Coronary Artery Disease
Nakamura, H., Ikewaki, K., NISHIWAKI, M., & Shige, H. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb17340.x · Cited by 15 · see citing works
Apo E-containing lipoproteins in low or high density lipoprotein deficiency.
Gibson, J. C., Rubinstein, A., Brown, W. V., Ginsberg, H. N., Greten, H., Norum, R. A., & Kayden, H. J. (1985) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.5.4.371 · Cited by 14 · see citing works
Concentrations of apoprotein CII, CIII, and E in total serum and in the apoprotein B-containing lipoproteins, determined by a new enzyme-linked immunosorbent assay
Alsayed, N., Rebourcet, R., & Chapman, J. (1990) · Clinical Chemistry · doi:10.1093/clinchem/36.12.2047 · Cited by 13 · see citing works
The ‘midband’ lipoprotein is a coronary risk factor in Japanese patients with familial hypercholesterolaemia
Tashiro, J., NISHIDE, T., Shinomiya, M., Shirai, K., Saito, Y., Yoshida, S., Yamashita, M., OHSHIMA, H., & Murayama, H. (1993) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365519309086624 · Cited by 12 · see citing works
Important contribution of lipoprotein particle number to plasma triglyceride concentration in type 2 diabetes
Steiner, G. A., Tkáč, I., Uffelman, K. D., & Lewis, G. F. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00256-6 · Cited by 10 · see citing works
Postprandial remnant-like particles and coronary artery disease
Ikewaki, K., Shige, H., Nakajima, K., & Nakamura, H. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)93348-0 · Cited by 9 · see citing works
Distribution of CII and CIII peptides in lipoprotein classes: methods and clinical significance
Graziani, M. S., Zanolla, L., Righetti, G., Marchetti, C., Zanotto, G., & Lupo, A. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.2.240 · Cited by 8 · see citing works
Ultracentrifugal evidence of a special subtype of mixed hyperlipidemia
Gennes, J. L. D., Dairou, F., Hamon, P., & Truffert, J. (1977) · Atherosclerosis · doi:10.1016/0021-9150(77)90167-8 · Cited by 7 · see citing works
Postprandial Hyperlipidemia and Coronary Artery Disease
Patsch, J. R. (1993) · Medical science symposia series · doi:10.1007/978-94-011-1703-6_9 · Cited by 6 · see citing works
Prevalence of Double Pre-Beta Lipoproteinemia in Hyperlipidemic Patients Is Influenced by Gender, Menopausal Status, and ApoE Phenotype
Cohn, J. S., Giroux, L.-M., Fortin, L.-J., & Davignon, J. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.11.2630 · Cited by 6 · see citing works
Self-citation
2.W15.1 Different approaches to the detection and quantification of triglyceride-rich lipoprotein remnants
Cohn, J. S., & Davignon, J. (1997) · Atherosclerosis · doi:10.1016/s0021-9150(97)88618-2 · Cited by 5 · see citing works
Self-citation
ELISA quantitation of apolipoproteins in plasma lipoprotein fractions: ApoE in apoB-containing lipoproteins (Lp B:E) and apoB in apoE-containing lipoproteins (Lp E:B)
Yang, C.-Y., Xie, Y.-H., Yang, M., Quion, J. A., & Gotto, A. M. (1995) · Journal of Protein Chemistry · doi:10.1007/bf01886876 · Cited by 4 · see citing works
Slowß-migrating lipoprotein: An atherogenic subclass of low density lipoproteins
Kawano, M., Shinomiya, M., Kanzaki, T., Morisaki, N., Shirai, K., Saito, Y., & Yoshida, S. (1996) · Clinical Biochemistry · doi:10.1016/0009-9120(96)00009-c · Cited by 4 · see citing works
Important information for contributors
Blombäck, B., & Copley, A. L. (1974) · Thrombosis Research · doi:10.1016/0049-3848(74)90048-6 · Cited by 3 · see citing works
Remnant-like lipoproteins concentration in plasma is strongly associated with early signs of carotid atherosclerosis in healthy 50-year old men.
Karpe, F., Bond, G., & Hamsten, A. (1998) · Circulation · Cited by 2 · see citing works

Flagged first, then by citations

1 of the 187 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

Scheafer EJ, Levy RI, Anderson DW, Danner RN, Brewer HB Jr, Blackwelder WC. Plasma triglycerides in the regulation of HDL. Lancet. 1978;2:391-393.
Eisenberg S. Remnant lipoprotein metabolism. In: Crepaldi G, Tiengo A, Manzato E, eds. Diabetes, Obesity and Hyperlipidemia: V. The Plurimetabolic Syndrome. New York, NY: Elsevier Science Publishers; 1993;7-14.
Lindgren FT, Jensen LC, Hatch FT. The isolation and quantitative analysis of serum lipoproteins. In: Nelson GJ, ed. Blood Lipids and Lipoproteins. New York, NY: John Wiley-Interscience; 1972: 181-274.
Avogaro P, Cazzolato G, Bittolo Bon G, Belussi F. Levels and chemical composition of HDL2, HDL3 and other major lipoprotein classes in survivors of myocardial infarction. Artery. 1979;5: 495-508.
Weintraub MS, Eisenberg S, Breslow JL. Different patterns of post- prandial metabolism in normals and type IIa, type III and type IV hyperlipoproteinemics: effects of treatment with cholestyramine and gemfibrozil. J Clin Invest. 1987;79:1110 -1119.

Sorted by citations

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Self-citation
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Self-citation
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Marcoux, C., Tremblay, M., Fredenrich, A., Davignon, J., & Cohn, J. S. (2001) · Metabolism · doi:10.1053/meta.2001.19452 · Cited by 41 · see citing works
Self-citation
The Role of Apolipoproteins in the Commonest Cancers: A Review
Darwish, N. M., Al‐Hail, M., Mohamed, Y. H., Al-Saady, R., Mohsen, S., Zar, A., Al-Mansoori, L., & Pedersen, S. (2023) · Cancers · doi:10.3390/cancers15235565 · Cited by 40 · see citing works
Cilostazol and atherogenic dyslipidemia: a clinically relevant effect?
Rizzo, M., Corrado, E., Patti, A. M., Rini, G. B., & Mikhailidis, D. P. (2011) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2011.557359 · Cited by 40 · see citing works
Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome
Mangat, R., Su, J. W., Scott, P. G., Russell, J. C., Vine, D. F., & Proctor, S. D. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350477 · Cited by 39 · see citing works
High Levels of Remnant Lipoprotein Cholesterol Is a Risk Factor for Large Artery Atherosclerotic Stroke
Kim, J. Y., Park, J., Jeong, S., Schellingerhout, D., Park, J.-E., Lee, D. K., Choi, W. J., Chae, S. L., & Kim, D. (2011) · Journal of Clinical Neurology · doi:10.3988/jcn.2011.7.4.203 · Cited by 40 · see citing works
Lipoprotein Abnormalities in Chronic Kidney Disease and Renal Transplantation
Barbagallo, C. M., Cefalu, A. B., Giammanco, A., Noto, D., Caldarella, R., Ciaccio, M., Averna, M. R., & Nardi, E. (2021) · Life · doi:10.3390/life11040315 · Cited by 40 · see citing works
Postprandial lipemia is modified by the presence of the polymorphism present in the exon 1 variant at the SR-BI gene locus
Pérez‐Martínez, P., López‐Miranda, J., Ordovás, J. M., Bellido, C., Marı́n, C., Gomez, P., Paniagua, J. A., Moreno, J., Fuentes, F. J., & Pérez‐Jiménez, F. (2004) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0320237 · Cited by 40 · see citing works
Plant Stanol Supplementation Decreases Serum Triacylglycerols in Subjects with Overt Hypertriglyceridemia
Theuwissen, E., Plat, J., Kallen, C., van Greevenbroek, M. M. J., & Mensink, R. P. (2009) · Lipids · doi:10.1007/s11745-009-3367-6 · Cited by 39 · see citing works
Remnant-like Particle-Cholesterol Concentrations in Patients with Type 2 Diabetes Mellitus and End-Stage Renal Disease
Hirany, S. V., O’Byrne, D., Devaraj, S., & Jialal, I. (2000) · Clinical Chemistry · doi:10.1093/clinchem/46.5.667 · Cited by 39 · see citing works
Obesity, Glucose Intolerance and Diabetes and Their Links to Cardiovascular Disease. Implications for Laboratory Medicine
Dominiczak, M. H. (2003) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2003.194 · Cited by 37 · see citing works
Remnant lipoproteins and atherosclerotic cardiovascular disease
Tada, H., Nohara, A., Inazu, A., Mabuchi, H., & Kawashiri, M.-A. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2018.12.014 · Cited by 37 · see citing works
Atherogenic Lipoproteins in Subclinical Hypothyroidism and Their Relationship with Hepatic Lipase Activity: Response to Replacement Treatment with Levothyroxine
Brenta, G., Berg, G. A., Miksztowicz, V., Lopez, G. I., Lucero, D., Faingold, C., Murakami, M., Machima, T., Nakajima, K., & Schreier, L. E. (2016) · Thyroid · doi:10.1089/thy.2015.0140 · Cited by 36 · see citing works
Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1
Yu, Y., Kuang, Y., Lei, D., Zhai, X., Zhang, M., Krauss, R. M., & Ren, G. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m070375 · Cited by 36 · see citing works
Methods to assess impaired post‐prandial metabolism and the impact for early detection of cardiovascular disease risk
Su, J. W., Nzekwu, M. M. U., Cabezas, M. C., Redgrave, T. G., & Proctor, S. D. (2009) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2009.02179.x · Cited by 33 · see citing works
Regulation of postprandial lipemia: an update on current trends.
Paglialunga, S., & Cianflone, K. (2007) · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · doi:10.1139/h06-100 · Cited by 33 · see citing works
Prognostic utility of triglyceride-rich lipoprotein-related markers in patients with coronary artery disease
Cao, Y., Zhang, H., Jin, J., Liu, H., Zhang, Y., Xu, R., Gao, Y., Guo, Y., Zhu, C., Hua, Q., et al. (2020) · Journal of Lipid Research · doi:10.1194/jlr.ra120000746 · Cited by 31 · see citing works
Detection of triglyceride using an iridium nano-particle catalyst based amperometric biosensor
Liao, W.-Y., Liu, C.-C., & Chou, T. (2008) · The Analyst · doi:10.1039/b801703d · Cited by 31 · see citing works
Triglyceride-rich lipoproteins, remnants and atherosclerotic cardiovascular disease: What we know and what we need to know
Chapman, M. J., Packard, C. J., Björnson, E., Ginsberg, H. N., & Borén, J. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.120529 · Cited by 32 · see citing works
Is Lipid Control Necessary in Hemodialysis Patients?
Cheung, A. K. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04780709 · Cited by 30 · see citing works
Effect of remnant-like particle on shear-induced platelet activation and its inhibition by antiplatelet agents
Yamazaki, M., Uchiyama, S., Xiong, Y., Nakano, T., Nakamura, T., & Iwata, M. (2004) · Thrombosis Research · doi:10.1016/j.thromres.2004.08.029 · Cited by 30 · see citing works
Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case–control study
Hopkins, P. N., Nanjee, M. N., Wu, L. L., McGinty, M. G., Brinton, E. A., Hunt, S. C., & Anderson, J. L. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.05.016 · Cited by 29 · see citing works
Storage of human plasma samples leads to alterations in the lipoprotein distribution of apoC-III and apoE
Cohn, J. S., Rodriguez, C., Jacques, H., Tremblay, M., & Davignon, J. (2004) · Journal of Lipid Research · doi:10.1194/jlr.d300041-jlr200 · Cited by 29 · see citing works
Self-citation
Pathophysiologic and Treatment Strategies for Cardiovascular Disease in End-Stage Renal Disease and Kidney Transplantations
Ghanta, M., Kozicky, M., & Jim, B. (2014) · Cardiology in Review · doi:10.1097/crd.0000000000000044 · Cited by 28 · see citing works
Construction of an amperometric TG biosensor based on AuPPy nanocomposite and poly (indole-5-carboxylic acid) modified Au electrode
Narang, J., Chauhan, N., Rani, P., & Pundir, C. S. (2012) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-012-0799-9 · Cited by 28 · see citing works
Post-prandial remnant lipids impair arterial compliance
Nestel, P. J., Shige, H., Pomeroy, S., Cehun, M., & Chin-Dusting, J. P. F. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01251-7 · Cited by 28 · see citing works
Therapeutic Effects of Fibrates in Postprandial Lipemia
Kolovou, G. D., Kostakou, P. M., Anagnostopoulou, K. K., & Cokkinos, D. V. (2008) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200808040-00004 · Cited by 27 · see citing works
Effect of fibrates on postprandial remnant-like particles in patients with combined hyperlipidemia
Ooi, T. C. (2003) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2003.10.016 · Cited by 27 · see citing works
Adult-Onset Growth Hormone Deficiency: Relation of Postprandial Dyslipidemia to Premature Atherosclerosis
Twickler, T. B., Cramer, M. J., Dallinga‐Thie, G. M., Chapman, M. J., Erkelens, D. W., & Koppeschaar, H. P. F. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030278 · Cited by 27 · see citing works
Effects of Atorvastatin Therapy on the Low-Density Lipoprotein Subfraction, Remnant-Like Particles Cholesterol, and Oxidized Low-Density Lipoprotein Within 2 Weeks in Hypercholesterolemic Patients
Sakabe, K., Fukuda, N., Wakayama, K., Nada, T., Shinohara, H., & Tamura, Y. (2003) · Circulation Journal · doi:10.1253/circj.67.866 · Cited by 25 · see citing works
Apolipoprotein B-48: comparison of fasting concentrations measured in normolipidaemic individuals using SDS–PAGE, immunoblotting and ELISA
Jackson, K. G., & Williams, C. M. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.02.003 · Cited by 24 · see citing works
Acute Coffee Ingestion Does Not Affect LDL Cholesterol Level
Cheung, R. J., Gupta, E. K., & Ito, M. K. (2005) · Annals of Pharmacotherapy · doi:10.1345/aph.1g005 · Cited by 24 · see citing works
Remnant Lipoproteins: Measurement and Clinical Significance
Jialal, I., & Devaraj, S. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.2.217 · Cited by 24 · see citing works
Remnant cholesterol predicts periprocedural myocardial injury following percutaneous coronary intervention in poorly-controlled type 2 diabetes
Zeng, R., Li, S., Zhang, M., Li, X., Zhu, C., Guo, Y., Zhang, Y., & Li, J. (2017) · Journal of Cardiology · doi:10.1016/j.jjcc.2016.12.010 · Cited by 23 · see citing works
Triglycerides and remnant particles as risk factors for coronary artery disease
Nakamura, T., & Kugiyama, K. (2006) · Current Atherosclerosis Reports · doi:10.1007/s11883-006-0047-3 · Cited by 23 · see citing works
Lab-on-a-chip for analysis of triglycerides based on a replaceable enzyme carrier using magnetic beads
Chen, S., Yu, X., Xu, J., & Chen, H. (2010) · The Analyst · doi:10.1039/c0an00231c · Cited by 21 · see citing works
Development of a Novel Homogeneous Assay for Remnant Lipoprotein Particle Cholesterol
Hirao, Y., Nakajima, K., Machida, T., Murakami, M., & Ito, Y. (2018) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2017.024919 · Cited by 21 · see citing works
Vascular Disease Risk in Patients With Hypertriglyceridemia: Endothelial Progenitor Cells, Oxidative Stress, Accelerated Senescence, and Impaired Vascular Repair
Thorin, É. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2011.03.014 · Cited by 21 · see citing works
New Insights Into How the Intestine Can Regulate Lipid Homeostasis and Impact Vascular Disease: Frontiers for New Pharmaceutical Therapies to Lower Cardiovascular Disease Risk
Warnakula, S., Hsieh, J., Adeli, K., Hussain, M. M., Tso, P., & Proctor, S. D. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.12.020 · Cited by 19 · see citing works
Accumulation of apoE-enriched triglyceride-rich lipoproteins in patients with coronary artery disease
Barbagallo, C. M., Rizzo, M., Noto, D., Frasheri, A., Pernice, V., Rubino, A., Pieri, D., Pinto, V., Cefalu, A. B., Giordano, C. S. D. S., et al. (2006) · Metabolism · doi:10.1016/j.metabol.2006.01.005 · Cited by 19 · see citing works
Risk Factors for Coronary Disease: the Time for a Paradigm Shift?
Dominiczak, M. H. (2001) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2001.147 · Cited by 19 · see citing works
Novel unbiased equations to calculate triglyceride-rich lipoprotein cholesterol from routine non-fasting lipids
Hermans, M. P., Ahn, S. A., & Rousseau, M. F. (2014) · Cardiovascular Diabetology · doi:10.1186/1475-2840-13-56 · Cited by 18 · see citing works
Time course differences for statin-induced pleiotropic effects in hypercholesterolemic patients
Sakabe, K., Fukuda, N., Wakayama, K., Nada, T., Shinohara, H., & Tamura, Y. (2004) · International Journal of Cardiology · doi:10.1016/j.ijcard.2003.08.001 · Cited by 18 · see citing works
Triglyceride content in remnant lipoproteins is significantly increased after food intake and is associated with plasma lipoprotein lipase
Nakajima, K., Tokita, Y., Sakamaki, K., Shimomura, Y., Kobayashi, J., Kamachi, K., Tanaka, A., Stanhope, K. L., Havel, P. J., Wang, T., et al. (2016) · Clinica Chimica Acta · doi:10.1016/j.cca.2016.12.011 · Cited by 17 · see citing works
Non-high-density lipoprotein cholesterol is a practical predictor of long-term cardiac death after coronary artery bypass grafting
Fukushima, Y., Ohmura, H., Mokuno, H., Kajimoto, K., Kasai, T., Hirayama, S., Miyauchi, K., Miida, T., Amano, A., & Daida, H. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.12.012 · Cited by 17 · see citing works
Influence of minor components of olive oils on the composition and size of TRLs and on macrophage receptors involved in foam cell formation
Cabello-Moruno, R., Perona, J. S., & Ruíz-Gutiérrez, V. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350470 · Cited by 17 · see citing works
Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels
Zhang, B., Böttcher, A., Imaizumi, S., Noda, K., Schmitz, G., & Saku, K. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.03.004 · Cited by 16 · see citing works
Implications of decreased serum adiponectin for type IIb hyperlipidaemia and increased cholesterol levels of very-low-density lipoprotein in type II diabetic patients
Yoshida, H., Hirowatari, Y., Kurosawa, H., & Tada, N. (2005) · Clinical Science · doi:10.1042/cs20040353 · Cited by 16 · see citing works
Measurement of serum remnant-like lipoprotein particle-triglyceride (RLP-TG) and RLP-TG/total TG ratio using highly sensitive triglyceride assay reagent
Nakano, T., Tokita, Y., Nagamine, T., Tanaka, A., Okazaki, M., Yatsuzuka, S.-I., Tamei, N., Shimomura, Y., Ando, Y., Akamatsu, S., et al. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.09.040 · Cited by 14 · see citing works
Increase in aortic pulse wave velocity is associated with abnormal postprandial triglyceride response
Daskalova, D. C., Kolovou, G. D., Panagiotakos, D. B., Pilatis, N. D., & Cokkinos, D. V. (2005) · Clinical Cardiology · doi:10.1002/clc.4960281208 · Cited by 14 · see citing works

Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease
Duran, E. K., & Pradhan, A. D. (2020) · Clinical Chemistry · doi:10.1093/clinchem/hvaa296 · Cited by 108 · see citing works
Remnant lipoproteins as therapeutic targets
Havel, R. J. (2000) · Current Opinion in Lipidology · doi:10.1097/00041433-200012000-00008 · Cited by 107 · see citing works
Development of a novel homogeneous assay for remnant lipoproteins
Satoh, N., Ikaida, M., & Ito, Y. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.07.562
Triglyceride-rich lipoproteins, remnants and atherosclerotic cardiovascular disease: What we know and what we need to know
Chapman, M. J., Packard, C. J., Björnson, E., Ginsberg, H. N., & Borén, J. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.120529 · Cited by 32 · see citing works
Remnant Lipoproteins: Measurement and Clinical Significance
Jialal, I., & Devaraj, S. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.2.217 · Cited by 24 · see citing works

Authors: Cohn, J. S., Marcoux, C., & Davignon, J.
Affiliations: Montreal Clinical Research Institute (CA)
ORCID: Cohn, Jeffrey S.
Davignon, Jean
Venue: Arteriosclerosis, Thrombosis, and Vascular Biology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1999-10
Volume: 19
Issue: 10
Pages: 2474-2486
ISSN: 1079-5642 (ISSN-L)
1524-4636
DOI: 10.1161/01.atv.19.10.2474
OpenAlex: W2162381401
Cited by: 156
References: 187
Citations by year: 2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 7 · 2019: 3 · 2018: 6 · 2017: 3 · 2016: 4 · 2015: 4 · 2014: 5 · 2012: 3
FWCI: 1.09
Type: journal article
Language: en
Open access: closed
Locations: Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
PubMed (publishedVersion)
Funders: Heart and Stroke Foundation of Canada
Otsuka America
Medical Research Council Canada
Medical Research Council
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
Keywords: atherogenic lipoproteins, apolipoprotein E, apolipoprotein B-48, apolipoprotein B-100, lipoprotein lipase, hepatic lipase, chylomicrons, VLDL, hypertriglyceridemia, coronary artery disease risk, atherosclerosis
MeSH terms: Arteriosclerosis, Humans, Lipoproteins, Triglycerides

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Detection, quantification, and characterization of potentially atherogenic triglyceride-rich remnant lipoproteins

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