Psychology of Chronic Pelvic Pain: Prevalence, Neurobiological Vulnerabilities, and Treatment
Open accessAbstract
Patients with pelvic pain suffer from psychological conditions at a disproportionately high rate compared with their peers. We review environmental, genetic, inflammatory, and neurobiological factors that increase vulnerability to developing both of these conditions. We review treatment strategies for chronic pelvic pain in patients who have comorbid psychological conditions, including both nonpharmacologic and pharmacologic options.
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There is a severe lack of quality studies with reference to what assessment measures, education concepts and mental health interventions are effective for use with women who have PPP.
“Currently there is a severe lack of quality studies with reference to what assessment measures, education concepts and mental health interventions are effective for use with women who have PPP.14”
From Psychological interventions for women with persistent pelvic pain: A survey of mental health clinicians (2021) · cites this paper as [14]
In Overview of treatment strategies > Non-pharmacologic options (page unavailable), the review says evidence for CBT in chronic pelvic pain is less robust than for other chronic pain conditions, supporting a research gap for mental health interventions. But it also reports increasing evidence of CBT efficacy, while Prevalence of psychological disorders in patients with CPP (page unavailable) says brief, high-quality symptom measures exist. It does not establish a severe lack of quality studies across assessment measures, education concepts, and mental health interventions as a whole. (LLM, conf=0.85)
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- Authors
- TILL, S. R., AS-SANIE, S., & SCHREPF, A.
- Affiliations
- Obstetrics and Gynecology
- University of Michigan (US)
- Corresponding author
- TILL, SARA R.
- Venue
- Clinical Obstetrics & Gynecology
- Published
- 2019-03
- Volume
- 62
- Issue
- 1
- Pages
- 22-36
- ISSN
- 0009-9201 (ISSN-L)
- PMC
- PMC6340718
- OpenAlex
- W2898956426
- Cited by
- 134
- References
- 134
- Citations by year
- 2026: 22 · 2025: 16 · 2024: 22 · 2023: 20 · 2022: 26 · 2021: 16 · 2020: 11 · 2019: 1
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Dental and Craniofacial Research (K12DE023574)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD088712)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Keywords
- chronic pelvic pain, psychological comorbidity, prevalence, neurobiological vulnerability, genetic factors, inflammation, pain management, non-pharmacological treatment, pharmacotherapy
- MeSH terms
- Serotonin and Noradrenaline Reuptake Inhibitors, Gabapentin, Antidepressive Agents, Tricyclic, Anxiety, Depression, Female, Humans, Cognitive Behavioral Therapy, Prevalence, Pelvic Pain, Twin Studies as Topic, Off-Label Use, Catastrophization, Chronic Pain
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