Short sleep duration and increased risk of hypertension: a primary care medicine investigation
Abstract
OBJECTIVES: Compelling evidence from laboratory-based and population-based studies link sleep loss to negative cardiovascular health outcomes. However, little is known about the association between sleep duration and hypertension in primary care health settings, independently of other well controlled clinical and biochemical characteristics. We investigated the association between sleep duration and the prevalence of hypertension adjusting for 21 potential confounding factors in a noncontrolled primary care sample. METHODS: The sample included 1046 French adults older than 40 years (mean age, 55.5 years), who visited any of the general practitioners of primary care centers in the Paris area. Blood pressure (BP) readings, blood samples and standardized health and sleep questionnaires were performed on each participant. Hypertension inclusion criteria were either high BP measurements (SBP ≥ 140 mmHg or DBP ≥ 90 mmHg) or the use of antihypertensive medications. Sleep duration was recorded as the self-reported average number of hours of sleep per night during the week. Logistic regressions were performed to test the association between hypertension and sleep duration adjusted for sociodemographic, clinical, biochemical, lifestyle, psychological and sleep disorder covariates. RESULTS: Compared to the group sleeping 7 h, individuals sleeping 5 h or less had an increased odds ratio (OR) for the prevalence of hypertension [OR = 1.80, 95% confidence interval (1.06-3.05)], after adjusting for 21 potential confounders which did not markedly attenuate this association. CONCLUSION: Our data provide further epidemiologic evidence that with no specific selection in primary care medicine, usual short-sleep duration increases the risk of hypertension prevalence in adults over 40 years.
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Individuals with obstructive sleep apnea or insomnia are at significantly greater risk for cardiovascular and cerebrovascular diseases and metabolic disorders.
“Population-based studies show that individuals with OSA or insomnia are at significantly greater risk for CVD and cerebrovascular diseases (eg, arrhythmias, atherosclerosis, coronary heart disease [CHD], heart failure, hypertension, and stroke) and metabolic disorders (eg, obesity, type 2 diabetes mellitus, and dyslipidemia).”
From Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health: A Scientific Statement From the American Heart Association (2016) · cites this paper as [7]
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“…associated with incident hypertension (Cappuccio et al., 2011; Meng et al., 2013), current hypertension (Altman et al., 2012; Fang et al., 2012; Faraut et al., 2012b; Grandner et al., 2014a; Wang et al., 2012), dyslipidemia (Altman et al., 2012; Gangwisch et al., 2010a; Grandner et al.,…”
BackgroundMethod
- Authors
- Faraut, B., Touchette, É., Gamble, H., Royant-Parola, S., Safar, M. E., Varsat, B., & Léger, D.
- Affiliations
- Sorbonne Paris Cité (FR)
- Université Paris-Sud (FR)
- Venue
- Journal of Hypertension
- Published
- 2012-07
- Volume
- 30
- Issue
- 7
- Pages
- 1354-1363
- ISSN
- 0263-6352 (ISSN-L)
- OpenAlex
- W2317083615
- Cited by
- 109
- References
- 44
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 4 · 2023: 8 · 2022: 6 · 2021: 10 · 2020: 7 · 2019: 11 · 2018: 6 · 2017: 7 · 2016: 7 · 2015: 9 · 2014: 12 · 2013: 7 · 2012: 2
- FWCI
- 12.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Keywords
- sleep duration, short sleep duration, hypertension, blood pressure, primary care, adults over 40, confounding adjustment, cardiovascular risk, antihypertensive medication use
- MeSH terms
- Adult, Blood Pressure, Female, Humans, Hypertension, Life Style, Male, Middle Aged, Primary Health Care, Surveys and Questionnaires, Risk Factors, Sleep, Confounding Factors, Epidemiologic
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