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Suicide risk in mood disorders
Abstract
PURPOSE OF REVIEW: The aim of this review is to highlight the traditional and newly recognized suicide risk factors in patients with mood disorders. RECENT FINDINGS: Current research findings clearly suggest that suicidal behaviour in patients with mood disorder is a 'state-dependent' phenomenon. Recently, there is, however, a growing body of evidence that besides the well accepted clinically explorable suicide risk factors in mood disorders (e.g., severe depression, prior suicide attempt, comorbid anxiety, substance use, personality disorders and so on), mixed state of depression could also be an important precursor of suicidal behaviour. This might be particularly true in unrecognized cases of bipolar depressives, when antidepressant monotherapy (unprotected by mood stabilizers or atypical antipsychotics) can worsen the clinical picture and rarely induce an aggressive or self-destructive behaviour. SUMMARY: In the majority of patients with mood disorders, suicidal behaviour is predictable and preventable, with a good chance. A careful and systematic exploration of suicide risk factors in patients with mood disorder helps clinicians to identify patients at high suicide risk. A successful, acute and long-term treatment of these patients substantially reduces the suicidal behaviour even in this high-risk population.
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“MDD is also associated with elevated risk of onset, persistence, and severity of a wide range of chronic physical disorders as well as with increased early mortality due to an even wider range of physical disorders and to suicide.”
From The Costs of Depression (2012) · cites this paper as [121]
In the citing paper
“MDD is associated with significantly elevated risk of early death.104, 106, 119 This is true partly because people with MDD have high suicide risk,120–122 but also because depression is associated with elevated risk of the many types of disorders noted above. MDD is also associated with elevated mortality risk among people with certain kinds of disorders as part of a larger pattern of associations”
From The Costs of Depression (2012) · cites this paper as [121]
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Metadata
- Authors
- Rihmer, Z.
- Affiliations
- Semmelweis University (HU)
- Corresponding author
- Rihmer, Zoltán
- Venue
- Current Opinion in Psychiatry
- Published
- 2007-01
- Volume
- 20
- Issue
- 1
- Pages
- 17-22
- ISSN
- 0951-7367 (ISSN-L)
- OpenAlex
- W2068198479
- Cited by
- 382
- References
- 59
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 13 · 2023: 16 · 2022: 15 · 2021: 12 · 2020: 20 · 2019: 15 · 2018: 17 · 2017: 19 · 2016: 29 · 2015: 21 · 2014: 24 · 2013: 27 · 2012: 24
- FWCI
- 2.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- suicide risk, mood disorders, suicide risk factors, bipolar depression, bipolar disorder, severe depression, previous suicide attempts, anxiety comorbidity, substance use, personality disorders, suicide prevention
- MeSH terms
- Adolescent, Adult, Cause of Death, Child, Humans, Risk Factors, Suicide, Suicide, Attempted, Comorbidity, Mood Disorders
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