CoChat
Sign Up
Cited by 58Tactile and Sensory InteractionsNeural dynamics and brain functionMotor Control and Adaptation

Exploring the cortical evidence of a sensory-discrimination process

Open access
Romo, Ranulfo, Hernández, Adrián, Zainos, Antonio, Brody, Carlos, Salinas, Emilio·2002·Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
DOI 10.1098/rstb.2002.1100PMC PMC1693008
Open this paper in CoChat — free account

Abstract

Humans and monkeys have similar abilities to discriminate the difference in frequency between two consecutive mechanical vibrations applied to their fingertips. This task can be conceived as a chain of neural operations: encoding the two consecutive stimuli, maintaining the first stimulus in working memory, comparing the second stimulus with the memory trace left by the first stimulus and communicating the result of the comparison to the motor apparatus. We studied this chain of neural operations by recording and manipulating neurons from different areas of the cerebral cortex while monkeys performed the task. The results indicate that neurons of the primary somatosensory cortex (S1) generate a neural representation of vibrotactile stimuli which correlates closely with psychophysical performance. Discrimination based on microstimulation patterns injected into clusters of S1 neurons is indistinguishable from that produced by natural stimuli. Neurons from the secondary somatosensory cortex (S2), prefrontal cortex and medial premotor cortex (MPC) display at different times the trace of the first stimulus during the working-memory component of the task. Neurons from S2 and MPC appear to show the comparison between the two stimuli and correlate with the behavioural decisions. These neural operations may contribute to the sensory-discrimination process studied here.

Integrity signals

Registry

Crossref · 10.1098/rstb.2002.1100

Cites

76 of 76 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The class of bounded sequential sampling models explains the tradeoff between speed and accuracy, and many of the essential steps have correlates in neurophysiology.

    “The class of bounded sequential sampling models, including many variants (Wald, 1947; Stone, 1960; Laming, 1968; Link, 1975; Good, 1979; Luce, 1986; Ratcliff and Rouder, 1998) explains the tradeoff between speed and accuracy, and many of the essential steps have correlates in neurophysiology (Romo et al., 2002; Heekeren et al., 2004; Ploran et al., 2007; Heitz and Schall, 2012; White et al., 2012;”

    From A common mechanism underlies changes of mind about decisions and confidence (2016) · cites this paper as Romo et al., 2002

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Romo, R., Hernández, A., Zainos, A., Brody, C., & Salinas, E.
Affiliations
Universidad Nacional Autónoma de México (MX)
Corresponding author
Romo, Ranulfo
ORCID
Venue
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
Publisher
The Royal Society
Published
2002-08-29
Volume
357
Issue
1424
Pages
1039-1051
ISSN
  • 0962-8436 (ISSN-L)
  • 1471-2970
DOI
10.1098/rstb.2002.1100
PMC
PMC1693008
OpenAlex
W2154183648
Cited by
58
References
76
Citations by year
2026: 2 · 2025: 1 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 4 · 2017: 3 · 2016: 8 · 2015: 6 · 2014: 2 · 2013: 1 · 2012: 3
FWCI
0.84
Type
journal article
Language
en
Open access
Licence
royalsociety.org/journals/ethics-policies/data-sharing-mining/ (tdm)
Locations
  • Philosophical Transactions of the Royal Society B Biological Sciences (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Howard Hughes Medical Institute
  • Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Keywords
vibrotactile discrimination, frequency discrimination, primary somatosensory cortex, secondary somatosensory cortex, prefrontal cortex, working memory, neural representations, microstimulation, behavioral decision making, tactile perception
MeSH terms
Animals, Haplorhini, Cerebral Cortex, Discrimination Learning, Humans, Memory, Neurons, Touch

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review