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Identification of a major QTL and associated marker for high arabinoxylan fibre in white wheat flour
Open accessPreprint — published as 10.1371/journal.pone.0227826
Abstract
Dietary fibre (DF) has multiple health benefits, and wheat products are major sources of DF for human health. However, DF is depleted in white flour, which is most widely consumed, compared to wholegrain. The major type of DF in white wheat flour is the cell wall polysaccharide arabinoxylan (AX). Previous studies have identified the Chinese wheat cultivar Yumai 34 as having unusually high contents of AX in both water-soluble and insoluble forms. We have therefore used populations generated from crosses between Yumai 34 and four other wheat cultivars, three with average contents of AX (Ukrainka, Altigo and Claire) and one also having unusually high AX (Valoris), in order to map QTLs for soluble AX (determined as relative viscosity) of aqueous extracts of wholemeal flours) and total AX (determined by enzyme fingerprinting of white flour). A number of QTL were mapped, but most were only detected in one or two crosses. However, all four crosses showed strong QTLs for high RV/total AX on chromosome 1B, with Yumai 34 being the increasing parent, and a KASP marker for the high AX Yumai 34 allele was validated by analysis of high AX lines derived from Yumai 34 but selected by biochemical analysis. A QTL for RV was mapped on chromosome 6B in Yumai 34 × Valoris, with Valoris being the increasing allele, which was consistent with the observation of transgressive segregation for this trait. The data indicate that breeding can be used to develop wheat with high AX fibre in white flour.
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Metadata
- Authors
- Lovegrove, A., Wingen, L. U., Plummer, A., Wood, A., Passmore, D., Kosik, O., Freeman, J., Mitchell, R. A. C., Ulker, M., Tremmel-Bede, K., Rakszegi, M., Bedő, Z., Petterant, M.-R., Charmet, G., Leverington Waite, M., Orford, S., Burridge, A., Pellny, T., Shewry, P. R., & Griffiths, S.
- Affiliations
- Rothamsted Research (GB)
- John Innes Centre (GB)
- HUN-REN Centre for Agricultural Research (HU)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- University of Bristol (GB)
- Corresponding author
- Shewry, Peter R
- ORCID
- Venue
- PLoS ONE
- Publisher
- openRxiv
- Published
- 2019-07-17
- Volume
- 15
- Issue
- 2
- Pages
- e0227826-e0227826
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC7001892
- OpenAlex
- W3005200226
- Cited by
- 40
- References
- 1
- Citations by year
- 2026: 8 · 2025: 5 · 2024: 9 · 2023: 7 · 2022: 2 · 2021: 3 · 2020: 6
- FWCI
- 2.91
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- PLoS ONE (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Bristol Research (University of Bristol) (publishedVersion, other-oa)
- Explore Bristol Research (publishedVersion, other-oa)
- Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) (acceptedVersion)
- HAL (submittedVersion, cc-by)
- Rothamsted Repository (Rothamsted Repository) (submittedVersion)
- Van Yüzüncü Yıl University Academic Data Management System (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
- Directorate for Biological Sciences (BB/P016855/1)
- Biotechnology and Biological Sciences Research Council (BBS/E/C/000I0280, BB/K007599/1, BB/ P016855/1, BBS/E/J/000PR9781, BB/F014996/1, BB/L027127/1, BB/L024543/1, BBS/E/J/000C0617, BB/L025108/1, BBS/E/J/000CA393, BB/T014237/1, BBS/E/C/000I0250, P016855/1)
- Innovate UK (L005654/1)
- National Research, Development and Innovation Office (BB/P016855/1)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Wheat and Barley Genetics and Pathology
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Keywords
- arabinoxylan, dietary fiber, white wheat flour, quantitative trait loci, chromosome 1B, chromosome 6B, KASP markers, viscosity ratio, marker-assisted breeding, transgressive segregation, wheat germplasm
- MeSH terms
- Alleles, Chromosome Mapping, Crosses, Genetic, Flour, Genetic Markers, Lod Score, Viscosity, Triticum, Xylans, Reproducibility of Results, Chromosomes, Plant, Quantitative Trait Loci, Genome-Wide Association Study
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