Skeletal Muscle as an Endocrine Organ: The Role of Myokines in Exercise Adaptations

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810

The Human Plasma Proteome

Anderson, N. L., & Anderson, N. G. (2002) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r200007-mcp200 · Cited by 4,414

Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

McPherron, A. C., Lawler, A. M., & Lee, S.-J. (1997) · Nature · doi:10.1038/387083a0 · Cited by 4,013

The Extracellular Matrix: Not Just Pretty Fibrils

Hynes, R. O. (2009) · Science · doi:10.1126/science.1176009 · Cited by 3,527

Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases

Pedersen, B. K., & Saltin, B. (2015) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.12581 · Cited by 3,514

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

HEINRICH, P. C., BEHRMANN, I., HAAN, S., HERMANNS, H. M., MÜLLER-NEWEN, G., & SCHAPER, F. (2003) · Biochemical Journal · doi:10.1042/bj20030407 · Cited by 3,272 · cited 1×

Muscles, exercise and obesity: skeletal muscle as a secretory organ

Pedersen, B. K., & Febbraio, M. A. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.49 · Cited by 2,909

The anti-inflammatory effects of exercise: Mechanisms and implications for the prevention and treatment of disease

Gleeson, M., Bishop, N. C., Stensel, D. J., Lindley, M. R., Mastana, S. S., & Nimmo, M. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3041 · Cited by 2,470

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

Egan, B., & Zierath, J. R. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2012.12.012 · Cited by 2,084

Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading

Kjær, M. (2004) · Physiological Reviews · doi:10.1152/physrev.00031.2003 · Cited by 1,649

Body Composition and Its Outcomes and Management in Multiple Sclerosis: Narrative Review

Kidwell-Chandler, A. L., Jackson, J., Jeng, B., Silveira, S. L., Pilutti, L. A., Hibbing, P. R., & Motl, R. W. (2025) · Nutrients · doi:10.3390/nu17061021 · Cited by 7

Optimization of high-intensity resistance exercise protocols for improving bone mineral density in the elderly without chronic diseases: a systematic review and network meta-analysis

Cheng, Y., Yi, Y., Bo, S., Jun, M., & Ma, J. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1589200 · Cited by 6

Febuxostat reduces muscle wasting in tumor-bearing mice with LM8 osteosarcoma cells via inhibition of reactive oxygen species generation

Tsukamoto, T., Tsujii, M., Odake, K., Iino, T., Nakamura, T., Matsumine, A., & Sudo, A. (2021) · Free Radical Research · doi:10.1080/10715762.2021.1947502 · Cited by 6

Body Composition, Fasting Blood Glucose and Lipidemic Indices Are Not Primarily Determined by the Nutritional Intake of Middle-Aged Endurance Trained Men—Another “Athletes’ Paradox”?

Methenitis, S. K., Feidantsis, K. G., Kaprara, A., Hatzitolios, A. I., Skepastianos, P., Papadopoulou, S. Κ., & Panayiotou, G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11206057 · Cited by 6

Myokines derived from contracting skeletal muscle suppress anabolism in MCF7 breast cancer cells by inhibiting mTOR

Davis, A. R., Goodenough, C. G., Westerlind, K. C., Strange, R., Deaver, J. W., Ryan, P. J., Riechman, S. E., & Fluckey, J. D. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1033585 · Cited by 6

Muscle-derived exosomes and exercise in cancer prevention

Vitucci, D., Martone, D., Alfieri, A., & Buono, P. (2023) · Frontiers in Molecular Medicine · doi:10.3389/fmmed.2023.1202190 · Cited by 7

High-intensity combination exercise has the highest effect on increasing serum irisin and interleukin 6 levels in women with obesity

Hasanah, U., Rejeki, P. S., Wungu, C. D. K., Pranoto, A., Izzatunnisa, N., Rahmanto, I., & Halim, S. (2024) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2023-0150 · Cited by 8

Changes in the Parameters of Quantal Acetylcholine Release after Activation of PAR1-Type Thrombin Receptors at the Mouse Neuromuscular Junctions

Gaydukov, A. E., Акутин, И. А., Bogacheva, P. O., & Balezina, O. P. (2018) · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology · doi:10.1134/s1990747818010063 · Cited by 6

Prognostic value of cardio-hepatic-skeletal muscle syndrome in patients with heart failure

Noda, T., Kamiya, K., Hamazaki, N., Nozaki, K., Ichikawa, T., Nakamura, T., Yamashita, M., Uchida, S., Maekawa, E., Reed, J. L., et al. (2021) · Scientific Reports · doi:10.1038/s41598-020-80641-2 · Cited by 6

Chronic Low or High Nutrient Intake and Myokine Levels

Sierra, A., de Fontes-Junior, A. A., Paz, I. A., Zocoler, C. A. S., Manoel, L. A. D. S., de Menezes, D. C., Rocha, V. A., Barbeiro, H. V., de Souza, H. P., & Cury‐Boaventura, M. F. (2022) · Nutrients · doi:10.3390/nu15010153 · Cited by 6

Targeting Mitochondria with Sweat: Improving Mitochondrial Function with Physical Activity

Beleza, J., Rizo‐Roca, D., Ascensão, A. A. M. R., & Magalhães, J. (2018) · Springer eBooks · doi:10.1007/978-3-319-73344-9_18 · Cited by 6

The new perspective of cardiac exercise rehabilitation: based on integrative physiology

You, G., Xie, J., Tong, W., & Zhao, S. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1651589 · Cited by 6

Metabolic crosstalk between skeletal muscle and cartilage tissue: insights into myokines in osteoarthritis

Shirvani, H., Shamsoddini, A., Bazgir, B., McAinch, A. J., Najjari, A., & Arabzadeh, E. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-11072-3 · Cited by 5

Comparative efficacy of various exercise interventions on sleep in patients with cognitive impairment: a systematic review and meta-analysis

Zhang, J., Liu, Y., Sun, Q., Shi, J., Ni, J., Li, T., Long, Z., Wei, M., & Tian, J. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1300459 · Cited by 7

Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

PRASAD, V. V., Samson, J. S., & Parvathi, V. D. (2024) · Biocell · doi:10.32604/biocell.2024.048776 · Cited by 6

Insulin Sensitivity and Muscle Loss in the Absence of Diabetes Mellitus: Findings from a Longitudinal Community-Based Cohort Study

Kim, H. J. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041270 · Cited by 8

Amino acid neurotransmitters in sarcopenia and healthy aging

Jonk, S. M., Tribble, J. R., Swoboda, P., & Williams, P. A. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111437 · Cited by 6

Delayed increase of acetylcholine quantal size induced by the activity‐dependent release of endogenous CGRP but not ATP in neuromuscular junctions

Bogacheva, P. O., & Balezina, O. P. (2020) · Synapse · doi:10.1002/syn.22175 · Cited by 5

Systematic training in master swimmer athletes increases serum insulin growth factor-1 and decreases myostatin and irisin levels

Curiel-Cervantes, V., Solís‐S, J. C., Camacho-Barrón, M., Aguilar-Galarza, A., Valencia, M. E., & Anaya‐Loyola, M. A. (2022) · Growth Factors · doi:10.1080/08977194.2022.2049262 · Cited by 5

Short bouts of walking attenuates the response of IL-8 to prolonged sitting in healthy adults

O’Rourke, N., Meens-Miller, E., Jeffrey, M. P., Saleem, L., Green-Johnson, J. M., & Dogra, S. (2023) · European Journal of Applied Physiology · doi:10.1007/s00421-023-05153-z · Cited by 6

Muscle Strength and Cardiovascular Health in MASLD: A Prospective Study

Kumbaroğlu, F. B., Balaban, Y. H., & Düger, T. (2025) · Medicina · doi:10.3390/medicina61020247 · Cited by 5

Relationship between different physical activity parameters and cognitive impairment in middle-aged and older adults: insights from a 4-year longitudinal study

Liu, D., Pan, Y., Wang, J., Shen, S., & Zhao, X. (2025) · BMC Psychology · doi:10.1186/s40359-025-02586-3 · Cited by 5

A Microfluidic Stretch System Upregulates Resistance Exercise-Related Pathway

Ahn, J., Kim, J.-S., Jeon, J. S., & Jang, Y. J. (2022) · BioChip Journal · doi:10.1007/s13206-022-00051-6 · Cited by 5

Methods for Proteomics-Based Analysis of the Human Muscle Secretome Using an In Vitro Exercise Model

Weigert, C., Hartwig, S., & Lehr, S. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1186-9_27 · Cited by 5

Obesity Status and Physical Fitness Levels in Male and Female Portuguese Adolescents: A Two-Way Multivariate Analysis

Encarnação, S., Rodrigues, F. F., Monteiro, A. M., Gouili, H., Hattabi, S., Sortwell, A., Branquinho, L., Teixeira, J. E., Ferraz, R., Flores, P., et al. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20126115 · Cited by 5

Physical Activity Guidelines for Astronauts: An Immunological Perspective

Hekmatikar, A. H. A., & Suzuki, K. (2025) · Biomolecules · doi:10.3390/biom15101390 · Cited by 4

Extraocular muscle-myokine-scleral remodeling axis: IL-6 trans-signaling as a novel mechanism in myopia development

Zhang, J., Zhao, J. M., Zheng, J., Zou, Z., Liu, Y., & An, M. (2025) · Experimental Eye Research · doi:10.1016/j.exer.2025.110740 · Cited by 4

Exercise-Induced Exerkines Modulate Autophagy: Implications for Interorgan Crosstalk in the Hallmarks of Ageing

Qi, D. E. N. G., Huang, J., Wang, C., & Liang, J. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062746 · Cited by 4

The effect of a cardiac rehabilitation program including moderate-intensity continuous exercise training and high-intensity interval exercise training on sarcopenia and myokines in patients with heart failure

Sönmez, M., Alemdaroğlu, E., Ata, A. M., Kafes, H., Ergüder, B. İ., Nojadeh, J. N., & Gökkaya, N. K. O. (2026) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2026.2677223 · Cited by 4

Inflammaging and Sarcopenia as Interconnected Hallmarks of Aging: Integrative Roles of Bioactive Compounds and Lifestyle Interventions

Nyáry, D., Fekete, M., Ceglédi, A., Fazekas‐Pongor, V., Lipécz, Á., Csípő, T., Major, D., Péterfi, A., Csík, B., Zábó, V., et al. (2026) · Nutrients · doi:10.3390/nu18121920 · Cited by 6

Separate and Combined Effects of Moderate-Intensity Exercise Training and Detraining with Protocatechuic Acid (PCA) on Myokines and Insulin-Signaling Pathways in Male Wistar Rats: A Preclinical Randomized Study

Shakoor, H. I., Kizhakkayil, J., Statsenko, Y. A., & Platat, C. (2025) · Metabolites · doi:10.3390/metabo15020087 · Cited by 4

Irisin Prevents the Effects of Simulated Microgravity on Bone and Muscle Differentiation Markers

Sanesi, L., Zerlotin, R., Campiolo, A., Oranger, A., Dicarlo, M., Suriano, C., Ghadiri, A., Colaianni, G., Grano, M., Tavella, S., et al. (2025) · FASEB BioAdvances · doi:10.1096/fba.2025-00085 · Cited by 4

Influence of skeletal muscle heterogeneity on autophagic signaling and response

Rahman, F. A., & Quadrilatero, J. (2025) · Autophagy Reports · doi:10.1080/27694127.2025.2562429 · Cited by 4

Upregulation of CCL5/RANTES Gene Expression in the Diaphragm of Mice with Cholestatic Liver Disease

Morales, V., González, A., & Cabello‐Verrugio, C. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-26163-3_11 · Cited by 4

Effects of Obesity in Old Age on the Basement Membrane of Skeletal Muscle in Mice

Kanazawa, Y., Ikeda‐Matsuo, Y., Sato, H., Nagano, M., Koinuma, S., Takahashi, T., Suzuki, H., Miyachi, R., & Shigeyoshi, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119209 · Cited by 4

Research Progress on the Effects of Different Exercise Modes on the Secretion of Exerkines After Spinal Cord Injury

Li, Q., Li, C., & Zhang, X. (2024) · Cellular and molecular neurobiology · doi:10.1007/s10571-024-01497-y · Cited by 5

MyomiR-OsteomiR crosstalk induced by different modes and intensities of exercise training and its role in controlling osteogenic differentiation in old male Wistar rats

Shanazari, Z., Farsani, Z. H., Faramarzi, M., & Banitalebi, E. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111305 · Cited by 4

The rationale for including osteopathic manipulative treatment in the management of infections: a hermeneutic review

Lesho, E. P., McKeown, A., & Laguio-Vila, M. R. (2021) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2021.1935236 · Cited by 4

Comparison of secreted miRNAs and proteins during proliferation and differentiation of bovine satellite cells in culture implies potential roles in regulating myogenesis

Nielsen, S. D.-H., Sahebekhtiari, N., Huang, Z., Young, J. F., & Rasmussen, M. K. (2023) · Gene · doi:10.1016/j.gene.2023.147979 · Cited by 4

Bioelectrical impedance vector applied to body composition evaluation of women survivors of breast cancer: A longitudinal study

Machado, V. M. Q., Justa, R. M. D. E., da Costa, S. L., Barbosa, M. C., Damasceno, N. R. T., & Verde, S. M. M. L. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.06.008 · Cited by 4

Meteorin-like (Metrnl) adipomyokine improves glucose tolerance in type 2 diabetes via AMPK pathwayPreprint

Lee, J. O., Lee, H. J., Lee, Y. W., Han, J. A., Kang, M. J., Moon, J., Shin, M., Lee, H. J., Chung, J. H., Lee, J., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/420489 · Cited by 4

Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle

Clemens, Z. J., Weaver, L., Brown, A., Kosaraju, J., Barchowsky, A., Miljkovic, I., & Sahu, A. (2025) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2025.2593824 · Cited by 3

The Myokine Adaptome in Health and Disease: Exercise-Induced Cellular Signaling, Muscle–Organ Crosstalk, and Therapeutic Plasticity

Mănescu, D. C., Plastoi, C. D., Pîrvan, A., Dîrnu, R., Floroiu, E. A., & Popescu, A. (2026) · Cells · doi:10.3390/cells15141236 · Cited by 5

Myokines are one of the key elements of interaction between skeletal muscles and other systems of human body necessary for adaptation to physical loads

Tymochko-Voloshyn, R. I., Hashchyshyn, V., Параняк, Н., Boretsky, V. Y., Решетило, С., & Boretsky, Y. (2023) · Visnyk of Lviv University Biological series · doi:10.30970/vlubs.2023.88.01 · Cited by 4

The mediating role of lower body muscle strength and IGF-1 level in the relationship between age and cognition. A MIDUS substudy

Gökçe, E., Kaushal, N., Fontanille, T., Vrinceanu, T., Saillant, K., Vints, W. A. J., Fréret, T., Gauthier, A., Bherer, L., & Langeard, A. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2024.112399 · Cited by 3

Linking Circulating Irisin and Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Aminov, E., Folan, P., & Pisconti, A. (2025) · JCSM Communications · doi:10.1002/rco2.70000 · Cited by 5

The Role of Endogenous Calcitonin Gene-Related Peptide in the Neurotransmitter Quantal Size Increase in Mouse Neuromuscular Junctions

Bogacheva, P. O., Golikova, E. A., & Balezina, O. P. (2018) · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology · doi:10.1134/s1990747818030029 · Cited by 3

Aerobic vs Resistance Exercise—An Endocrine Perspective

Bansal, N., Kotwal, N., & Kumar, S. (2020) · Journal of Medical Academics · doi:10.5005/jp-journals-10070-0057 · Cited by 3

Exercise as a protagonist in muscle plasticity and in the muscle as an endocrine organ: implications in chronic diseases

Vargas-Pacheco, A., & Correa-López, L. E. (2021) · Revista de la Facultad de Medicina Humana · doi:10.25176/rfmh.v22i1.4129 · Cited by 3

Effects of Vibrotherapy with Different Characteristics and Body Position on Post-Exercise Recovery after Anaerobic Exercise

Pałka, T., Maciejczyk, M., Czerwińska‐Ledwig, O., Tota, Ł. M., Bawelski, M., Leiva-Arcas, A., Stabrawa, R., Bujas, P., Mucha, D. K., Wiśniewski, A., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12144629 · Cited by 3

A cross-sectional study investigating the relationship between handgrip strength with multimorbidity in Korean adults

Lee, M.-R., & Jung, S. M. (2021) · Medicine · doi:10.1097/md.0000000000023994 · Cited by 3

Die parakrine und endokrine Funktion der Muskulatur

Heitkamp, H. (2023) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-023-2493-z · Cited by 2

Oct-B: A derivative of L-BAIBA significantly alleviating high-fat diet-induced obesity in mice

Wang, J., Wei, S., Guo, J., Xie, X., Sun, W., Zhao, S., Meng, J., Wang, F., Wang, J., Rong, R., et al. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150739 · Cited by 2

A Single Intraperitoneal Secreted Protein Acidic and Rich in Cysteine Injection in Mice Is Towards an Exercise-like Phenotype

Ghanemi, A., Yoshioka, M., & St‐Amand, J. (2025) · Biology · doi:10.3390/biology14040398 · Cited by 2

Metabolic and immune links between sarcopenia and liver disease

Kotlyarov, S. N. (2025) · World Journal of Hepatology · doi:10.4254/wjh.v17.i8.109444 · Cited by 2

How Exercise Affects Exerkines in Metabolic Syndrome

Babaei, P., & Yadegari, F. (2025) · Hormone and Metabolic Research · doi:10.1055/a-2720-5398 · Cited by 2

Longitudinal monitoring of handgrip strength in rheumatoid arthritis: a window into for disease activity—a systematic review with meta-analysis

Santo, R. C. D. E., dos Santos, L. P., Melo, G. L. R., Dubey, V. P., & Agostinis‐Sobrinho, C. (2025) · BMJ Open Sport & Exercise Medicine · doi:10.1136/bmjsem-2025-002617 · Cited by 2

The myokine musclin in metabolic syndrome: Pathological links and exercise interventions

Wen, R., Yang, Y., Wang, H., Teng, Y., Zhao, B., Zhu, H., & Wang, S. (2025) · iScience · doi:10.1016/j.isci.2025.114367 · Cited by 2

Association of Circulating Irisin with Insulin Resistance and Metabolic Risk Markers in Prediabetic and Newly Diagnosed Type 2 Diabetes Patients

Sakizlian, D. D. M., Boldeanu, L., Clenciu, D., Mitrea, A., Vladu, I. M., Plasiciuc, A. E. C., Assani, M.-Z., & Ciobanu, D. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27020787 · Cited by 2

The Skeletal Muscle as an Endocrine Firewall: Mitigating Metabolic Endotoxemia and Insulin Resistance in Polycystic Ovary Syndrome

Li, Q., Wu, Y., Chen, L., & Wang, R. (2026) · Current Obesity Reports · doi:10.1007/s13679-026-00703-w · Cited by 2

Effect of Beetroot Nitrate Supplementation on Nitric Oxide Pathways and Oxy-Inflammatory Biomarkers in Amateur Triathletes: A Randomized Cross-Over Pilot Study

Mrakic‐Sposta, S., Vezzoli, A., Parenza, M., Magno, M., D'Angelo, G., Nannipieri, F., Battaglia, S., Solfanelli, L., Tacconi, E., Dellanoce, C., et al. (2026) · Nutrients · doi:10.3390/nu18081215 · Cited by 2

Moringa protein drink increases testosterone and anabolic status of men with hyperlipidemia: A randomized controlled study

Juan, C. G. (2021) · Turkish Journal of Kinesiology · doi:10.31459/turkjkin.851832 · Cited by 2

Muscle-kidney crosstalk; the role of myokines

Moonesan, M. R. (2023) · Journal of Renal Endocrinology · doi:10.34172/jre.2023.25129 · Cited by 2

Advancing cancer cachexia diagnosis with -omics technology and exercise as molecular medicine

Hesketh, S. J. (2024) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2024.01.006 · Cited by 3

Lifestyle modifications and nutritional modulation of immune system for prevention and management of diabetes mellitus: Current perspectives

Srividya, N., Haldipur, A. C., & Yerra, H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13195-0.00016-8 · Cited by 3

The Effect of Aerobic Exercise and Pistachio Soft Hull Extract on the Expression of the Il-6 and IL-1β Genes in the Soleus Muscle of Female Rats Fed a High-Fat Diet

Barshan, H., Azarbayjani, M. A., Rahmati-Ahmadabad, S., & Peeri, M. (2024) · Gene Cell and Tissue · doi:10.5812/gct-144065 · Cited by 2

Association of sarcopenia with regional brain atrophy and white matter lesions in a general older population: the Hisayama Study

Tajimi, T., Hirabayashi, N., Furuta, Y., Nakazawa, T., Honda, T., Hata, J., Ohara, T., Shibata, M., Kitazono, T., Nakashima, Y., et al. (2024) · GeroScience · doi:10.1007/s11357-024-01289-8 · Cited by 2

Relationship of irisin and apelin levels with sarcopenia and body composition in community-dwelling older adults: a paired case–control study

Zhang, L., Peng, Y., Qie, Y., Guo, J., Kong, Y., Zhang, X., Li, Z., & Jia, H. (2025) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2024-0473 · Cited by 3

Molecular mechanisms of adaptive and therapeutic effects of physical activity in patients with cardiovascular diseases

Vladimirsky, V. E., Vladimirsky, E. V., Lunina, A. N., Fesyun, A. D., Rachin, A. P., Lebedeva, O. D., Yakovlev, M. Y., & Tubekova, M. (2022) · Problems of Balneology Physiotherapy and Exercise Therapy · doi:10.17116/kurort20229902169 · Cited by 2

Regenerative Rehabilitation for Nonlethal Muscular Dystrophies

Roche, J. A. (2022) · Physiology in health and disease · doi:10.1007/978-3-030-95884-8_3 · Cited by 2

Irisin expression and FNDC5 (rs3480) gene polymorphism in type 2 diabetic patients with and without CAD

Foad, A. M., Hafez, A., Youssef, W., Ahmed, A. E., & Altaher, A. M. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2023.2173785 · Cited by 2

CÂNCER, SISTEMA IMUNOLÓGICO E EXERCÍCIO FÍSICO: UMA REVISÃO NARRATIVA

Nogueira, H. S., & Lima, W. P. (2018) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 2

Recommended Hints for Improved Lifestyle and Health from Integrative Medicine (IM) In the Critical Situation of COVID-19

Bando, H. (2020) · doi:10.36502/2020/droa.6164 · Cited by 2

Influence of Interleukin-2 on Adaptive Reactions of Blood in Laboratory Mice under Physical Activity Conditions

Shvets, V. A., Hasiuk, O., & Бесчасный, С. П. (2020) · Ukraïnsʹkij žurnal medicini bìologìï ta sportu · doi:10.26693/jmbs05.05.349 · Cited by 2

Walk This Way—Early Mobility for ICU Patient Recovery*

Engel, H. J. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004279 · Cited by 2

Respostas das concentrações de miocinas a partir do estímulo do exercício físico: uma revisão sistemática

Carvalho, L. P. D. C., Oliveira, Í. C. D. S., Gomes, M. B. D. C., Santos, P. H. S., de Oliveira, A. C., Vitavar, L. M. G., & Alves, H. B. (2021) · Revista Brasileira de Fisiologia do Exercício · doi:10.33233/rbfex.v19i5.4630 · Cited by 1

The effectiveness of physical activity in cardiorehabilitation

Yakovlev, M. Y., Lebedeva, O. D., Vladimirsky, V. E., Vladimirsky, E. V., & Lunina, A. N. (2022) · Sports medicine research and practice · doi:10.47529/2223-2524.2022.1.1 · Cited by 1

Special Issue “Adipokines, Myokines, and Physical Exercise in Health and Disease 2.0”

Bilski, J., & Brzozowski, T. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020940 · Cited by 1

A Pilot Study Investigating the Impact of High Altitude on Myostatin and Irisin Levels

Rathor, R., Suryakumar, G., & Singh, S. N. (2024) · Defence Life Science Journal · doi:10.14429/dlsj.9.19449 · Cited by 1

Concurrent Resistance and Cardiorespiratory Training in Patients with Hypertrophic Cardiomyopathy: A Pilot Study

Bayonas‐Ruiz, A., Muñoz‐Franco, F. M., Molina, M. S., González-Moro, I. M., Gimeno, J. R., & Bonacasa, B. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082324 · Cited by 1

Sporda Dayanıklılık ve Aerobik Dayanıklılık Testleri

Atasever, G., & Kıyıcı, F. (2024) · Özgür Yayınları eBooks · doi:10.58830/ozgur.pub640.c2773 · Cited by 1

Egzersizde Protein Sentezi ve Etkileyen Faktörler

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The Influence of an Acute Endurance Intervention on Breast Cancer Cell Growth—A Pilot Study

Gunasekara, N., Clauss, D., Voss, A., Schurz, K., Fleck, K., Neu-Gil, P., & Bloch, W. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26093976 · Cited by 1

Effect of Exercise‐Induced Hormonal Changes on Skeletal Muscle Physiology

Shi, S. (2025) · Clinical Endocrinology · doi:10.1111/cen.70086 · Cited by 1

Exerkines in diabetic retinopathy: from mechanisms to therapeutic prospects

Zhu, J. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1762255 · Cited by 1

Suppressed brain-derived neurotrophic factor response to 6 min walking exercise in mild cognitive impairment

Kang, M. C., Wandel, S. M. D., Perez, C. N., Deutz, N. E. P., & ENGELEN, M. P. K. J. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106561 · Cited by 1

MG53, a Regenerative Myokine Linking Skeletal Muscle to Cardiac Repair

Chen, Y., Lee, K. E., Kim, J., Ko, J., & Park, K. H. (2026) · Biomolecules · doi:10.3390/biom16040524 · Cited by 1

Assessment of BMI percentages of obesity thresholds and cardiometabolic risk factors in children and adolescents: a retrospective cross-sectional study in Beijing

Xiao, L., Zeng, Y., Zheng, S. H., Wang, X., Guo, Z. C., Cui, Y., Tang, R., Guo, L.-L., & Li, J. (2026) · Lipids in Health and Disease · doi:10.1186/s12944-026-02940-3 · Cited by 1

Effect of prolonged sitting with stair climbing exercise “snacks” on circulating myokines profiles

Fujie, S. J., Rafiei, H., Kanemoto, M., Konishi, S., Iemitsu, M., & Little, J. P. (2026) · European Journal of Applied Physiology · doi:10.1007/s00421-026-06229-2 · Cited by 1

BNIP3 ‐Dependent Mitophagy Non‐Autonomously Regulates Systemic Aging via NF ‐ κB Suppression in Drosophila

Deng, Z., Han, H., Wang, C., Zhong, W., Wan, Z., Zhou, D., Chen, Y., Peng, Y., Zhai, Z., Yuan, K., et al. (2026) · Aging Cell · doi:10.1111/acel.70539 · Cited by 1

The emerging role of the Hippo signaling pathway in interorgan crosstalk

Song, G., Lee, C., & Jho, E. (2026) · FEBS Journal · doi:10.1111/febs.70587 · Cited by 1

Exercise Training in Hypertrophic Cardiomyopathy: A Systematic Review, Meta-analysis, and Meta-regression

Bayonas‐Ruiz, A., Gimeno, J. R., Muñoz‐Franco, F. M., Molina, M. S., & Bonacasa, B. (2026) · Sports Medicine - Open · doi:10.1186/s40798-026-01059-0 · Cited by 1

Nonlinear association between age and verbal fluency and moderation by adiposity: cross-sectional evidence from the Look Up 8+ study

Giordano, G., Mastrantoni, L., Calvani, R., Terranova, R., D’Ignazio, F., Risoli, A., Landi, F., Landi, F., Bernabei, R., Marzetti, E., et al. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1912213 · Cited by 1

Acercamiento multifactorial a la fisiopatología de la obesidad. Modelo de abordaje COD2

Rosero, R., Uribe, J. P., Jaramillo, A. M. A., Polanco, J. P., Rizo, P. C., Jaramillo, A. U., Salazar, I. C., Arbeláez, J. P. Á., & Cendales, J. G. (2019) · Revista Repertorio de Medicina y Cirugía · doi:10.31260/repertmedcir.v28.n3.2019.954 · Cited by 1

Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis

Han, X. X., Holst, J. J., & Galbo, H. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12050837 · Cited by 1

Körperliche Aktivität im Kontext Diabetes mellitus

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Potential mechanisms of exercise in maintaining skin homeostasis disrupted by protein deficiency (Review)

Kastella, F., Tarawan, V. M., Setiawan, I., Gunawan, D., Jasaputra, D. K., Goenawan, H., Gunadi, J. W., & Lesmana, R. (2024) · World Academy of Sciences Journal · doi:10.3892/wasj.2024.235 · Cited by 2

Exercise Suppresses Head and Neck Squamous Cell Carcinoma Growth via Oncostatin M

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Circulating miRNA Signaling for Fatty Acid Metabolism in Response to a Maximum Endurance Test in Elite Long-Distance Runners

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Aging with Heart Failure: Muscle Matters

Mourtzakis, M., Heckman, G. A., & McKelvie, R. S. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.09.032 · Cited by 1

Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines

Pedersen, B. K. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00734.2009 · Cited by 221

Myokines are one of the key elements of interaction between skeletal muscles and other systems of human body necessary for adaptation to physical loads

Tymochko-Voloshyn, R. I., Hashchyshyn, V., Параняк, Н., Boretsky, V. Y., Решетило, С., & Boretsky, Y. (2023) · Visnyk of Lviv University Biological series · doi:10.30970/vlubs.2023.88.01 · Cited by 4

Skeletal Muscle, Myokines and Health

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Muscle–Organ Crosstalk: The Emerging Roles of Myokines

Severinsen, M. C. K., & Pedersen, B. K. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa016 · Cited by 1,226

[Secretory Function of Skeletal Muscles: Producing Mechanisms and Myokines Physiological Effects].

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