Wnt signaling and cancer

Polakis, Paul·2000·Genes & Development

Cited by (1,004)

Items 501–600 of 1,004

  1. Frequent mutations of <i>β‐catenin</i> gene in sporadic secreting adrenocortical adenomas*
    Tadjine, Mimi, Lampron, Antoine, Ouadi, Lydia, Bourdeau, Isabelle · 2008 · Clinical Endocrinology
  2. ACCELERATED LIVER REGENERATION AND HEPATOCARCINOGENESIS IN MICE OVEREXPRESSING SERINE-45 MUTANT BETA-CATENIN
    Kari Nejak-Bowen, M. D. Thompson, Sucha Singh, W. Bowen, Mohd Jamal Dar, J. Khillan, Chun-Sun Dai, Satdarshan P. S. Monga · 2010 · Hepatology
  3. The role of the Wnt signalling pathway in colorectal tumorigenesis
    Jürgen Behrens · 2005 · Biochemical Society Transactions
  4. Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
    Sripathi M. Sureban, Randal J. May, Fadee G. Mondalek, Dongfeng Qu, Sivapriya Ponnurangam, Panayotis Pantazis, Shrikant Anant, Rama P. Ramanujam, Courtney W. Houchen · 2011 · Journal of Nanobiotechnology
  5. NF-κB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach
    Sharon Amit, Yinon Ben‐Neriah · 2003 · Seminars in Cancer Biology
  6. ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with β-catenin defects and promotes neoplastic transformation
    Frank Thomas Kolligs, Marvin T. Nieman, Ira Seth Winer, Gang Hu, David Van Mater, Ying Feng, Ian M. Smith, RONG TSUN WU, Yali Zhai, Kathleen R. Cho et al. · 2002 · Cancer Cell
  7. Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection between β-Catenin Pools
    Yoonseok Kam, Vito Quaranta · 2009 · PLoS ONE
  8. Current Understanding on EGFR and Wnt/ -Catenin Signaling in Glioma and Their Possible Crosstalk
    Indranil Paul, S. Bhattacharya, A. Chatterjee, Mrinal K. Ghosh · 2013 · Genes & Cancer
  9. WISP-1 Is an Osteoblastic Regulator Expressed During Skeletal Development and Fracture Repair
    Dorothy M. French, Raji J. Kaul, Aloma L. D’Souza, Craig W. Crowley, Min Bao, Gretchen D. Frantz, Ellen H. Filvaroff, Luc Desnoyers · 2004 · American Journal Of Pathology
  10. RETRACTED: Regulation of p53: intricate loops and delicate balances
    Moshe Oren, Alexander Damalas, Tanya M. Gottlieb, Dan Michael, Jan Taplick, Juan Fernando Martínez-Leal, Ruth Ben-Yakar Maya, Miri Moas, Rony Seger, Yoichi Taya et al. · 2002 · Biochemical Pharmacology · Retracted
  11. Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP
    Konstantinos Nikopoulos, Hanka Venselaar, Rob W.J. Collin, Rosa Riveiro-Álvarez, F. Nienke Boonstra, Johanna M. M. Hooymans, Arijit Mukhopadhyay, Deborah J. Shears, Marleen van Bers, Ilse J. de Wijs et al. · 2010 · Human Mutation
  12. Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
    B. McCartney, Donald G. McEwen, E. Grevengoed, P. Maddox, A. Bejsovec, M. Peifer · 2001 · Nature Cell Biology
  13. Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line
    Osamu Maeda, Noriyasu Usami, Masashi Kondo, Masahide Takahashi, Hidemi Goto, Kaoru Shimokata, Kazuo Kusugami, Yoshitaka Sekido · 2003 · Oncogene
  14. Negative regulation of the Wnt–β‐catenin pathway by the transcriptional repressor HBP1
    Ellen M. Sampson, Zaffar K. Haque, Manching Ku, Sergei G. Tevosian, Chris Albanese, Richard G. Pestell, K.Eric Paulson, Amy S. Yee · 2001 · The EMBO Journal
  15. Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer
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  16. Rethinking WNT signaling
    Tolwinski, Nicholas S, Wieschaus, Eric · 2004 · Trends in Genetics
  17. SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway
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  18. Crosstalk between the Androgen Receptor and β-Catenin in Castrate-Resistant Prostate Cancer
    Gang Wang, Jun Wang, Marianne D. Sadar · 2008 · Cancer Research
  19. The role of WNT signaling in adult ovarian folliculogenesis
    Jennifer A Hernandez Gifford · 2015 · Reproduction
  20. New insights into testicular germ cell tumorigenesis from gene expression profiling.
    Rolf Inge Skotheim, Outi M. Monni, Spyro Mousses, Sophie D. Fosså, Olli Kallioniemi, Ragnhild A. Lothe, Anne H. Kallioniemi · 2002 · PubMed
  21. Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.
    Marc van de Wetering, Nick Barker, I C Harkes, Marcel A. G. van der Heyden, N J Dijk, Antoinette Hollestelle, J.G.M. Klijn, Hans C. Clevers, Mieke E. M. Schutte · 2001 · PubMed
  22. Gastrointestinal stem cells in development and cancer
    Simone Brabletz, Otto Schmalhofer, Thomas Brabletz · 2008 · The Journal of Pathology
  23. Activation of the Canonical Wnt Pathway during Genital Keratinocyte Transformation: A Model for Cervical Cancer Progression
    Aykut Üren, Shannon Fallen, Hang Yuan, Alp Usubutün, Türkan Küçükali, Richard Schlegel, Jeffrey A. Toretsky · 2005 · Cancer Research
  24. β-Catenin and TGFβ signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition
    Andreas Eger, Andreas Stockinger, John Park, Elke Langkopf, Mario Mikula, Josef Gotzmann, Wolfgang Mikulits, Hartmut Beug, Roland Foisner · 2004 · Oncogene
  25. Adenomatous Polyposis Coli (APC)-independent Regulation of β-Catenin Degradation via a Retinoid X Receptor-mediated Pathway
    J.H. Xiao, Corine R. Ghosn, Cory Hinchman, Chad Forbes, Jenny W. Wang, Nonna Snider, Allison Cordrey, Yi Zhao, Roshantha A.S. Chandraratna · 2003 · Journal of Biological Chemistry
  26. Differential Signaling Pathways Are Activated in the Epstein-Barr Virus-Associated Malignancies Nasopharyngeal Carcinoma and Hodgkin Lymphoma
    Jennifer Adele Morrison, Margaret L. Gulley, Pathmanathan Rajadurai, Nancy Raab‐Traub · 2004 · Cancer Research
  27. Targeting the β-catenin nuclear transport pathway in cancer
    Cara Jamieson, Manisha Sharma, Beric R. Henderson · 2014 · Seminars in Cancer Biology
  28. Cytoplasmic Localization of β-Catenin is a Marker of Poor Outcome in Breast Cancer Patients
    Elena López‐Knowles, Sarah J. Zardawi, Catriona M. McNeil, Ewan K.A. Millar, Paul Crea, Elizabeth A. Musgrove, Robert L. Sutherland, Sandra A O'Toole · 2010 · Cancer Epidemiology Biomarkers & Prevention
  29. Targeting a cornerstone of radiation resistance: Cancer stem cell
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  30. CD73 as a potential opportunity for cancer immunotherapy
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  31. Regulation of β-Catenin Function by the IκB Kinases
    Carmela Lamberti, Keng Lin, Yumi Yamamoto, Udit N. Verma, Inder M. Verma, Steven Byers, Richard B. Gaynor · 2001 · Journal of Biological Chemistry
  32. Wnt signaling in breast cancer: have we come full circle?
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  33. Endostatin is a potential inhibitor of Wnt signaling
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  34. Genetic alterations in hepatoblastoma and hepatocellular carcinoma: Common and distinctive aspects
    Marie Annick Buendia · 2002 · Medical and Pediatric Oncology
  35. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila
    Kent E. Nybakken, Norbert Perrimon · 2002 · Biochimica et Biophysica Acta (BBA) - General Subjects
  36. Possible linkage between specific histological structures and aberrant reactivation of the Wnt pathway in adamantinomatous craniopharyngioma
    Keisuke Kato, Yukio Nakatani, Hiroshi Kanno, Yoshiyuki Inayama, Rieko Ijiri, Noriyuki Nagahara, Tetsumi Miyake, Mio Tanaka, Yumi Ito, Noriko Aida et al. · 2004 · The Journal of Pathology
  37. Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect
    Mi Hee Kwack, Bo Mi Kang, Moon Kyu Kim, Jung Chul Kim, Young Kwan Sung · 2011 · Journal of Dermatological Science
  38. Inhibition of Wnt signaling pathway decreases chemotherapy-resistant side-population colon cancer cells.
    Nobuhito Chikazawa, Haruo Tanaka, Takehiko Tasaka, Masafumi Nakamura, Masao Tanaka, Hideya Onishi, Mitsuo Katano · 2010 · PubMed
  39. Armadillo/β-catenin signals in the nucleus – proof beyond a reasonable doubt?
    M. Bienz, H. Clevers · 2003 · Nature Cell Biology
  40. Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding β‐catenin
    Alexander J. Lazar, Eduardo J. Calonje, Wayne Grayson, Angelo Paolo Dei Tos, Martín C. Mihm, Mark S. Redston, Phillip H. McKee · 2004 · Journal of Cutaneous Pathology
  41. Perturbed Neurogenesis in the Adult Hippocampus Associated with Presenilin-1 A246E Mutation
    Nathalie L. Chevallier, Salvador Soriano, David E. Kang, Eliezer Masliah, Gloria Hu, Edward H. Koo · 2005 · American Journal Of Pathology
  42. CTNNB1 Mutations and Overexpression of Wnt/β-Catenin Target Genes in WT1-Mutant Wilms' Tumors
    Chi-Ming Li, Connie E. Kim, Adam A. Margolin, Meirong Guo, Jimmy Zhu, Jacqueline M. Mason, Terrence Hensle, Vundavalli V.V.S. Murty, Paul Edward Grundy, Eric R. Fearon et al. · 2004 · American Journal Of Pathology
  43. IKKα Regulates Mitogenic Signaling through Transcriptional Induction of Cyclin D1 via Tcf
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  44. Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development
    Antonio J. Giráldez, Stephen Michael Cohen · 2003 · Development
  45. Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas.
    Donald R. Schwartz, RONG TSUN WU, Sharon L. R. Kardia, Albert M. Levin, Chiang-Ching Huang, Kerby Shedden, Rork D. Kuick, David E. Misek, Samir Hanash, Jeremy M. G. Taylor et al. · 2003 · PubMed
  46. Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice1
    Pradeep Singh Tanwar, Ho‐Joon Lee, LiHua Zhang, Lawrence R. Zukerberg, Makoto Mark Taketo, Bo R. Rueda, Jose M. Teixeira · 2009 · Biology of Reproduction
  47. β-Catenin Mutations Are Frequent in Calcifying Odontogenic Cysts, but Rare in Ameloblastomas
    Shigeki Sekine, Sunao Sato, Takashi Takata, Yasuo Fukuda, Takeshi Ishida, Mitsunobu Kishino, Tatsuhiro Shibata, Yae Kanai, Setsuo Hirohashi · 2003 · American Journal Of Pathology
  48. Endothelial cadherins and tumor angiogenesis
    Ugo Cavallaro, Stefan Liebner, Elisabetta Dejana · 2005 · Experimental Cell Research
  49. NMDA-Receptor Activation Induces Calpain-Mediated β-Catenin Cleavages for Triggering Gene Expression
    Kentaro Abe, Masatoshi Takeichi · 2007 · Neuron
  50. The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells
    Roberta Malaguarnera, Antonino Belfiore · 2014 · Frontiers in Endocrinology
  51. Phosphatases in cell–matrix adhesion and migration
    Melinda Larsen, Michel L. Tremblay, Kenneth M. Yamada · 2003 · Nature Reviews Molecular Cell Biology
  52. Growth factors regulate β-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing
    Sophia S. Cheon, Puviindran Nadesan, Raymond W.M. Poon, Benjamin Aaron Alman · 2003 · Experimental Cell Research
  53. Wnt signaling in B-cell neoplasia
    Ya‐Wei Qiang, Yoshimi Endo, Jeffrey S. Rubin, Stuart Rudikoff · 2003 · Oncogene
  54. Overexpression of Human Dickkopf-1, an Antagonist of wingless/WNT Signaling, in Human Hepatoblastomas and Wilms' Tumors
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  55. Hepatitis C Virus NS5A-Mediated Activation of Phosphoinositide 3-Kinase Results in Stabilization of Cellular β-Catenin and Stimulation of β-Catenin-Responsive Transcription
    Andrew Street, Andrew Macdonald, Christopher J. McCormick, Mark Harris · 2005 · Journal of Virology
  56. Phosphorylation by the β-Catenin/MAPK Complex Promotes 14-3-3-Mediated Nuclear Export of TCF/POP-1 in Signal-Responsive Cells in C. elegans
    Lo, Miao-Chia, Gay, Frédérique, Odom, Raanan, Shi, Yang, Lin, Rueyling · 2004 · Cell
  57. Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways
    Armen S. Manoukian, James Robert Woodgett · 2002 · Advances in cancer research
  58. DWnt4 Regulates Cell Movement and Focal Adhesion Kinase during Drosophila Ovarian Morphogenesis
    E.David Cohen, Marie‐Christine Mariol, Rachel M.H. Wallace, Jason Weyers, Yana G. Kamberov, Jacques Pradel, Elizabeth L. Wilder · 2002 · Developmental Cell
  59. Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled
    Feng Cong, Liang Schweizer, HAROLD E. VARMUS · 2004 · Molecular and Cellular Biology
  60. How do they do Wnt they do?: regulation of transcription by the Wnt/β‐catenin pathway
    Hilary C. Archbold, Youqi Yang, L. Chen, Ken M. Cadigan · 2011 · Acta Physiologica
  61. Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations
    Ce Liu, Yanyang Tu, Xiaoyang Sun, Jian Wei Jiang, Xiaodong Jin, Xiangfei Bo, Zhengming Li, Antai Bian, Xiaodong Wang, Dai Liu et al. · 2010 · Clinical and Experimental Medicine
  62. Wnt/β-catenin Signaling in Normal and Cancer Stem Cells
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  63. SOX9 Is Expressed in Normal Prostate Basal Cells and Regulates Androgen Receptor Expression in Prostate Cancer Cells
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  64. CBP/p300 are bimodal regulators of Wnt signaling
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  65. Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300
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  66. Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells
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  67. Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity
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  68. A Constitutively Active NFATc1 Mutant Induces a Transformed Phenotype in 3T3-L1 Fibroblasts
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  69. NF-κB: arresting a major culprit in cancer
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  71. Fra-1 a target for cancer prevention or intervention
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  72. The Soluble Wnt Receptor Frizzled8CRD-hFc Inhibits the Growth of Teratocarcinomas In vivo
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  73. Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
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  74. The Anticancer Effect of Fucoidan in PC-3 Prostate Cancer Cells
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  75. Small-molecule synergist of the Wnt/β-catenin signaling pathway
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  76. WNT Signaling and Lymphocyte Development
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  77. Small-Molecule Inhibitors of Phosphatidylinositol 3-Kinase/Akt Signaling Inhibit Wnt/β-Catenin Pathway Cross-Talk and Suppress Medulloblastoma Growth
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  78. Recent Advances in the Regulation of Brassinosteroid Signaling and Biosynthesis PathwaysF
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  79. Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells
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  80. Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region
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  81. Prickle-1 Negatively Regulates Wnt/β-Catenin Pathway by Promoting Dishevelled Ubiquitination/Degradation in Liver Cancer
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  85. PEA3 Is Up-regulated in Response to Wnt1 and Activates the Expression of Cyclooxygenase-2
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  86. Novel Cross Talk of Krüppel-Like Factor 4 and β-Catenin Regulates Normal Intestinal Homeostasis and Tumor Repression
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  87. Wnt Genes in the Mouse Uterus: Potential Regulation of Implantation1
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  88. Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal–ventral axis in the limb
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  92. Molecular causes of colon cancer
    Irma M. Oving, Hans C. Clevers · 2002 · European Journal of Clinical Investigation
  93. The Wnt/beta-catenin pathway in adrenocortical development and cancer
    El Wakil, Abeer, Lalli, Enzo · 2011 · Molecular and Cellular Endocrinology
  94. Wnt‐5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP‐2
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  95. Wnt3a Growth Factor Induces Androgen Receptor-Mediated Transcription and Enhances Cell Growth in Human Prostate Cancer Cells
    Meletios Verras, Jeffrey D. Brown, Xiaomeng Li, Roeland Nusse, Zijie Sun · 2004 · Cancer Research
  96. A Novel Mechanism for Wnt Activation of Canonical Signaling through the LRP6 Receptor
    Guizhong Liu, Anna Bafico, Violaine Harris, Stuart A. Aaronson · 2003 · Molecular and Cellular Biology
  97. Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes
    K. Macaulay, J. Woodgett · 2008 · Expert opinion on therapeutic targets
  98. The Human Frizzled 6 (HFz6) Acts as a Negative Regulator of the Canonical Wnt·β-Catenin Signaling Cascade
    Tamar Golan, A. Yaniv, Anna Bafico, Guizhong Liu, Arnona Gazit · 2004 · Journal of Biological Chemistry
  99. Wnts induce migration and invasion of myeloma plasma cells
    Ya‐Wei Qiang · 2005 · Blood
  100. Regulation of the Wnt signaling pathway by disabled‐2 (Dab2)
    Barbara A. Hocevar, F. Mou, Jessica Rennolds, S.M. Morris, Jonathan A. Cooper, Philip H. Howe · 2003 · The EMBO Journal