Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

FGF-21 as a novel metabolic regulator

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The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

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The FGF family: biology, pathophysiology and therapy

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

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Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

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Nutritional Regulation of the Insulin-Like Growth Factors*

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Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

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Bone, Growth Plate and Mineral Metabolism

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Growth factors reviews

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Prostate Cancer, Apoptosis, Autophagy and Ferroptosis: Cell Death Mechanisms and Their Cross-talk

Hashemi, M., Hosseini, A. S., Monjezi, S., Hasany, S., Binaei, S., Nejat, M., Melyani, H., Bashandeh, N., Matinahmadi, A., Zayani, Z., et al. (2024) · Springer eBooks · doi:10.1007/978-981-97-4612-5_4 · Cited by 1

Fibroblast growth factor signaling and spermatogonial stem cell self-renewal.

Yang, M., Whelan, E. C., Zeng, Y., Wei, X., Shi, L., & Yang, F. (2025) · Molecular human reproduction · doi:10.1093/molehr/gaaf039 · Cited by 1

FGF21 Conducts a Metabolic Orchestra and Fat Is a Key Player

Whittle, A. J. (2016) · Endocrinology · doi:10.1210/en.2016-1193 · Cited by 1

The Physiology and Pharmacology of Diabetic Gastropathy Management

Dolan, R. D., Rohani, T. S., Muttineni, D., & Mashimo, H. L. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00045-1 · Cited by 1

Herbal medicine of Kursi Wufarikun Ziyabit inhibits mitochondrial ATP production to activate AMPK in hepatocytes in therapy of type 2 diabetesPreprint

Yasen, M., Jiang, L., Sharofova, M. U., Xin, X., Nuraliev, Y., Ye, J., & Aisa, H. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.28.316349 · Cited by 1

Metabolic and mitogenic functions of fibroblast growth factor 1

Struik, D. (2020) · doi:10.33612/diss.133879075 · Cited by 1

Roles of ABCG5 ABCG8 cholesterol transporter in lipid homeostasis

Wang, Y. (2015) · UKnowledge (University of Kentucky)

Mix ‘n’ match estrogens

Uhlenhaut, N. H. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.01.004

IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY

Nelson, B. T. (2012)

Nuclear Receptor Regulation

Makishima, M. (2017) · Springer eBooks · doi:10.1007/978-4-431-56062-3_4

Factors Regulating Features of Metabolic Syndrome

Pijut, S. S. (2017) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2017.044

Bile Acids and FGF19 in the Remission of Type 2 Diabetes After Sleeve Gastrectomy and Gastric Bypass

Nemati, R. (2017) · Tuwhera (Auckland University of Technology)

Fibroblast Growth Factors in Development

Kinnunen, T. K. (2019) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0003306.pub2

The role of gastrointestinal hormones in the pathogenesis and the treatment of obesity

Puchta, U., Siewiec, E., Szczerbiński, Ł., Citko, A., Hady, H. R., & Kretowski, A. J. (2018) · Postępy Nauk Medycznych · doi:10.25121/pnm.2018.31.3.165

Structural basis of FGF23 hormone signaling

Zinkle, A., Goetz, R. M., Chen, L., & Mohammadi, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818036-5.00002-1

Metabolic and Electrophysiological Effects of Fibroblast Growth Factor 19 in the Dorsal Vagal Complex

Wean, J. (2021) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2021.383

A novel approach to growth hormone therapyPreprint

Боміхов, О. В. (2022) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/qsnka

Biliverdin and Bilirubin as Parallel Products of CO Formation

Vı́tek, L. (2022) · doi:10.1002/9781119783435.ch10

Expression Regulation and Bioactivity of Fibroblast Growth Factor 19/15

白, 玉. (2022) · Pharmacy Information · doi:10.12677/pi.2022.113020

Data from ST6GAL1 Is a Novel Serum Biomarker for Lenvatinib-Susceptible FGF19-Driven Hepatocellular Carcinoma

Myojin, Y., Kodama, T., Maesaka, K., Motooka, D., Sato, Y., Tanaka, S., Abe, Y., Ohkawa, K., Mita, E., Hayashi, Y., et al. (2023) · doi:10.1158/1078-0432.c.6530342.v1

Data from ST6GAL1 Is a Novel Serum Biomarker for Lenvatinib-Susceptible FGF19-Driven Hepatocellular Carcinoma

Myojin, Y., Kodama, T., Maesaka, K., Motooka, D., Sato, Y., Tanaka, S., Abe, Y., Ohkawa, K., Mita, E., Hayashi, Y., et al. (2023) · doi:10.1158/1078-0432.c.6530342

Relationship between Carotid Intima-Media Thickness and Fibroblast Growth Factor Binding Protein-3 in Patients with Metabolic Syndrome

Akdağ, G., & Altunoğlu, E. (2023) · Istanbul Medical Journal · doi:10.4274/imj.galenos.2023.19626

Therapeutic Implications of Capsaicin in Diabetes

Kaur, A., Verma, M., Bhandari, R., & Kuhad, A. (2024) · Springer eBooks · doi:10.1007/978-981-99-7779-6_18

Fibroblast growth factor 21 responds to taurocholic acid sodium-induced acute pancreatic injury

Zhang, L., Lin, Y., Ma, X., Xu, F., & Li, P. (2025) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2025.110761

Incorporation of unnatural amino acid into human acidic fibroblast growth factor 1 (FGF1) protein with increased thermal, chemical stability and enhanced bioactivity

Tabatabaei, R. T., Alraawi, Z., Fan, C., Adams, P., & Kumar, T. K. S. (2025) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2025.110706

Body mass index mediates the association between serum fibroblast growth factor-19 and diabetes

Liu, L., Liu, S., Zhen, J., Ren, L., Zhao, G., Liang, J., Xu, A., Li, C., Wu, J., & Cheung, B. M. Y. (2026) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01850-y

Emerging therapeutic approaches in neurobiology of type 2 diabetes

Kumar, U., Garg, S., Shrivastav, A., Sharma, B., Arora, B., Sahu, B., & Gupta, M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-32848-0.00023-6

Vital functions of WT1 during renal progenitor life

Motamedi, F. J. (2015) · theses.fr (ABES) · doi:10.70675/9b62ba64zdf74z4b3bzbb3fz122536d2a8f6

Nuclear receptors in age-related diseases: From mechanisms to drug discovery

Zhang, L., Li, X., Ren, C., Hao, Y., Deng, Y., Pan, H., Kim, Y.-B., Fan, S., Huang, C., Ge, G., et al. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103125 · Cited by 1

Influence of bile acids metabolism on hepatic immunity in mice

Guinot, V. (2022) · theses.fr (ABES) · doi:10.70675/b69bb11eza30fz4874z9af2za6e31b2d5ad8

Fibroblast growth factors in ischemic stroke: Therapeutic potential and clinical challenges

Dordoe, C., Kai-ming, G., Bwalya, C., Huang, W., Chen, S., Chen, J., Wang, X., Wang, P., Li, X., & Li, L. (2026) · Acta Pharmacologica Sinica · doi:10.1038/s41401-026-01832-7 · Cited by 1

Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases

Chui, Z. S. W., Xue, Y., Wu, X., & Xu, A. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100150

Gut microbiome and diabetes: Emerging perspectives in metabolic regulation

Kaur, N., Kaur, N., Verma, A., & Sharma, R. K. (2026) · Scripta Medica · doi:10.5937/scriptamed57-61236

Positive actions of fibroblast growth factor 21 on female zebrafish reproductive axis

Uju, C. N., & Unniappan, S. (2026) · Theriogenology · doi:10.1016/j.theriogenology.2026.118106

Allosteric β-Klotho Modulation to Restore FGF21 Sensitivity in Type 2 DiabetesPreprint

Andrade, L. J. D. O., de Oliveira, G. C. M., Bittencourt, A. M. V., Salles, O. J. D. M., & de Oliveira, L. M. (2026) · Research Square · doi:10.21203/rs.3.rs-10986278/v1

Genetically predicted associations between inflammatory cytokines and juvenile idiopathic arthritis

Pang, J., Pan, L., Liu, P., Qin, W., Yang, J., Feng, Y., He, S., & 杨水华 (2026) · Medicine · doi:10.1097/md.0000000000051005

The gastrointestinal KATP-ERK signaling axis: Molecular mechanisms, pharmacological opportunities, and emerging translational technologies

Denora, M., Turi, A. D., Maqoud, F., Antonacci, M., Orlando, A., Drago, S., Malerba, E., Russo, F., & Tricarico, D. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119986

Effects of Hypoxic Preconditioning and Endurance Exercise on Circulating Fibroblast Growth Factor 21 in Mice

Kon, M., Ato, S., & Matsuo, K. (2026) · International Journal of Sports Medicine · doi:10.1055/a-2975-4387

BindingDB Entry 50049049: 2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors.

BindingDB (2019) · UC San Diego · doi:10.7270/q2319z4p

Coordinated adipose–liver metabolic remodelling reveals sex-specific peripheral adaptations during amyotrophic lateral sclerosis progression in TDP-43A315T micePreprint

Benito-Casado, C., Ferrer-Donato, Á., Barroso-García, G., Domínguez-Vías, G., Domínguez-Rubio, R., Povedano, M., & Fernández-Martos, C. M. (2026) · Research Square · doi:10.21203/rs.3.rs-11467142/v1

Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state

Guan, D., Zhao, L., Chen, D., Yu, B., & Yu, J. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0821-0 · Cited by 36

Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21

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Metabolic roles of endocrine fibroblast growth factors

Fernandes-Freitas, I., & Owen, B. M. (2015) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2015.09.014 · Cited by 46

Minireview: Roles of Fibroblast Growth Factors 19 and 21 in Metabolic Regulation and Chronic Diseases

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Emerging role of fibroblast growth factors 15/19 and 21 as metabolic integrators in the liver

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