The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
Open accessAbstract
There is growing evidence that sonic hedgehog (Shh) signaling regulates ventral neuronal fate in the vertebrate central nervous system through Nkx -class homeodomain proteins. We have examined the patterns of neurogenesis in mice carrying a targeted mutation in Nkx6.1 . These mutants show a dorsal-to-ventral switch in the identity of progenitors and in the fate of postmitotic neurons. At many axial levels there is a complete block in the generation of V2 interneurons and motor neurons and a compensatory ventral expansion in the domain of generation of V1 neurons, demonstrating the essential functions of Nkx6.1 in regional patterning and neuronal fate determination.
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Cites
Sussel, L., Marin, O., Kimura, S., & Rubenstein, J. L. R. (1999) · Development · doi:10.1242/dev.126.15.3359 · Cited by 873
Self-citationWeiss, J. B., Von Ohlen, T., Mellerick, D. M., Dressler, G., Doe, C. Q., & Scott, M. P. (1998) · Genes & Development · doi:10.1101/gad.12.22.3591 · Cited by 236 · cited 1×
“1 to function as a repressor of the dorsally expressed Gsh1/2 homeobox genes parallels the ability of Drosophila NK2 to repress 2138 GENES & DEVELOPMENT Ind, a Gsh1/2-like homeobox gene (Weiss et al. 1998).”
BackgroundGsh ‐ 1 : A novel murine homeobox gene expressed in the central nervous system
Valerius, M. T., Li, H., Stock, J. L., Weinstein, M., Kaur, S., Singh, G., & Potter, S. S. (1995) · Developmental Dynamics · doi:10.1002/aja.1002030306 · Cited by 107
Cited by
Neuronal specification in the spinal cord: inductive signals and transcriptional codes
Jessell, T. M. (2000) · Nature Reviews Genetics · doi:10.1038/35049541 · Cited by 2,089
Self-citationDirected Differentiation of Embryonic Stem Cells into Motor Neurons
Wichterle, H., Lieberam, I., Porter, J. A., & Jessell, T. M. (2002) · Cell · doi:10.1016/s0092-8674(02)00835-8 · Cited by 1,728
Self-citation1 Developmental roles and clinical significance of Hedgehog signaling
McMahon, A. P., Ingham, P. W., & Tabin, C. J. (2003) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)53002-2 · Cited by 772
Novitch, B. G., Chen, A. I., & Jessell, T. M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00407-x · Cited by 615
Self-citationPancreas organogenesis: From bud to plexus to gland
Pan, F. C., & Wright, C. (2011) · Developmental Dynamics · doi:10.1002/dvdy.22584 · Cited by 614
Metadata
- Authors
- Sander, M., Paydar, S., Ericson, J., Briscoe, J., Berber, E., German, M., Jessell, T. M., & Rubenstein, J. L. R.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2000-09-01
- Volume
- 14
- Issue
- 17
- Pages
- 2134-2139
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2066729924
- Cited by
- 265
- References
- 3
- Type
- posted content
- Language
- en
- Open access
- diamond
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- The paper
- Sander, M., Paydar, S., Ericson, J., Briscoe, J., Berber, E., German, M., Jessell, T. M., & Rubenstein, J. L. R. (2000). Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes & Development. https://doi.org/10.1101/gad.820400
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