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KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

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GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling

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KSR2 Is a Calcineurin Substrate that Promotes ERK Cascade Activation in Response to Calcium Signals

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Navigating the ERK1/2 MAPK Cascade

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MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation

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The Scaffold Protein CNK1 Interacts with the Tumor Suppressor RASSF1A and Augments RASSF1A-induced Cell Death

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A Plant-Specific Polarity Module Establishes Cell Fate Asymmetry in the Arabidopsis Stomatal LineagePreprint

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Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR‐1 kinase and PP2A phosphatase

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The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis

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Integrated analysis of breast cancer cell lines reveals unique signaling pathways

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Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway

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Signal Transduction: IMPlications for Ras-Dependent ERK Signaling

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Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila

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Kinase Suppressor of Ras 1 (KSR1) Regulates PGC1α and Estrogen-Related Receptor α To Promote Oncogenic Ras-Dependent Anchorage-Independent Growth

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Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf 1

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Role of Raf Proteins in Cardiac Hypertrophy and Cardiomyocyte Survival

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Extracellular Signal-regulated Kinase Regulates Clathrin-independent Endosomal Trafficking

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A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in DrosophilaPreprint

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Protein kinases and their involvement in the cellular responses to genotoxic stress

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Loss-of-Function CNKSR2 Mutation Is a Likely Cause of Non-Syndromic X-Linked Intellectual Disability

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Signal control through Raf: in sickness and in health

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NME/NM23/NDPK and Histidine Phosphorylation

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The Molecular Scaffold Kinase Suppressor of Ras 1 Is a Modifier of Ras V12 -Induced and Replicative Senescence

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NM23-H1: a Metastasis-Associated Gene

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Identification of a Novel Human Kinase Supporter of Ras (hKSR-2) That Functions as a Negative Regulator of Cot (Tpl2) Signaling

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IQGAP1: A Regulator of Intracellular Spacetime Relativity

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Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections

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Molecular pathways in the development of HPV-induced cervical cancer

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Role of Phosphatidic Acid in the Coupling of the ERK Cascade

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The integration of signaling by multiprotein complexes containing Raf kinases

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KSR1 Modulates the Sensitivity of Mitogen-Activated Protein Kinase Pathway Activation in T Cells without Altering Fundamental System Outputs

Lin, J., Harding, A. S., Giurisato, E., & Shaw, A. S. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01634-08 · Cited by 42

Structural snapshots of RAF kinase interactions

Adariani, S. R., Buchholzer, M., Akbarzadeh, M., Nakhaei‐Rad, S., Dvorský, R., & Ahmadian, M. R. (2018) · Biochemical Society Transactions · doi:10.1042/bst20170528 · Cited by 41

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling

Rajakulendran, T., Sahmi, M., Kurinov, I. V., Tyers, M., Therrien, M., & Sicheri, F. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709705105 · Cited by 43

Regulation of response to nanopolystyrene by intestinal microRNA mir-35 in nematode Caenorhabditis elegans

Li, D., Yuan, Y., & Wang, D. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.139677 · Cited by 41

Bimodal regulation of RAF by CNK in Drosophila

Douziech, M., Roy, F., Laberge, G., Lefrançois, M., Armengod, A., & Therrien, M. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg506 · Cited by 42

A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway

Popov, I. A., Hiatt, S. M., Whalen, S., Keren, B., Ruivenkamp, C. A. L., van Haeringen, A., Chen, M.-J., Cooper, G. M., Korf, B. R., & Chang, C. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00388 · Cited by 41

Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo

Grewal, S., Molina, D. M., & Bardwell, L. (2005) · Cellular Signalling · doi:10.1016/j.cellsig.2005.04.001 · Cited by 41

Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton

Harrison, R. E., Sikorski, B. A., & Jongstra, J. (2004) · Journal of Cell Science · doi:10.1242/jcs.00955 · Cited by 41

The dual function of KSR1: a pseudokinase and beyond

Zhang, H., Koo, C.-Y., Stebbing, J., & Giamas, G. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130042 · Cited by 43

Nuclear Export and Plasma Membrane Recruitment of the Ste5 Scaffold Are Coordinated with Oligomerization and Association with Signal Transduction Components

Wang, Y., & Elion, E. A. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-10-0699 · Cited by 40

Scaffold Role of DUSP22 in ASK1-MKK7-JNK Signaling Pathway

Ju, A., Cho, Y.-C., Kim, B. R., Park, S. G., Kim, J., Kim, K., Lee, J., Park, B. C., & Cho, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164259 · Cited by 36

KSR: a MAPK scaffold of the Ras pathway?

Morrison, D. K. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.9.1609 · Cited by 233

KSR Regulation of the Raf‐MEK‐ERK Cascade

Ritt, D. A., Daar, I. O., & Morrison, D. K. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(05)07019-9 · Cited by 21

Kinase Suppressor of Ras (KSR) Is a Scaffold Which Facilitates Mitogen-Activated Protein Kinase Activation In Vivo

Nguyen, A., Burack, R., Stock, J. L., Kortum, R. L., Chaika, O. V., Afkarian, M., Muller, W. J., MURPHY, K. M. M., Morrison, D. K., Lewis, R. E., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.9.3035-3045.2002 · Cited by 269

MAP Kinase Module: The Ksr Connection

Roy, F., & Therrien, M. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00831-x · Cited by 30

Signaling dynamics of the KSR1 scaffold complex

McKay, M. M., Ritt, D. A., & Morrison, D. K. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901590106 · Cited by 163