Verbal and Nonverbal Emotional Memory Following Unilateral Amygdala Damage
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The amygdala is involved in the normal facilitation of memory by emotion, but the separate contributions of the left and right amygdala to memory for verbal or nonverbal emotional material have not been investigated. Fourteen patients with damage to the medial temporal lobe including the amygdala (seven left, seven right), 18 brain-damaged, and 36 normal controls were exposed to emotional and neutral pictures accompanied by verbal narratives. Memory for both narratives and pictures was assessed with a free recall test 24 h later. Subjects with left amygdala damage failed to show the normally robust enhancement of memory for verbal and nonverbal emotional stimuli. The group with right amygdala damage showed the normal pattern of facilitation of memory by emotion for both verbal and nonverbal stimuli despite an overall reduction in memory performance. Furthermore, subjects with left amygdala damage were disproportionately impaired on memory for emotional narratives as compared with memory for emotional pictures. The latter finding offers partial support for a lateralized and material-specific pattern of the amygdala's contribution to emotional memory.
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Left lateralised amygdala damage abolishes the normal enhancement of verbal memory by emotional valence, while the right amygdala may mediate a similar effect for visual information.
“Further evidence suggests that specifically left lateralised damage abolishes the normal enhancement of verbal memory by emotional valence (Buchanan et al., 2001;Edith Frank and Tomaz, 2003) while the right amygdala may mediate a similar effect for visual information (Markowitsch, 1998).”
From Affective Cognition and its Disruption in Mood Disorders (2011) · cites this paper as Buchanan et al., 2001
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- Authors
- Buchanan, T. W., Denburg, N. L., Tranel, D., & Adolphs, R.
- Affiliations
- University of Iowa (US)
- Venue
- Learning & Memory
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2001-11-01
- Volume
- 8
- Issue
- 6
- Pages
- 326-335
- ISSN
- 1072-0502 (ISSN-L)
- 1549-5485
- PMC
- PMC311388
- OpenAlex
- W2017912366
- Cited by
- 84
- References
- 46
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 5 · 2022: 1 · 2021: 2 · 2020: 1 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 5 · 2013: 2 · 2012: 6
- Type
- posted content
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Learning & Memory (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Funders
- National Institutes of Health (5r29mh057905-02)
- National Institute of Mental Health (R29 MH57905-03)
- National Institute of Neurological Disorders and Stroke (P01NS019632, NS-19632)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Keywords
- amygdala, emotional memory, verbal memory, nonverbal memory, hemispheric lateralization, medial temporal lobe, emotional pictures, emotional narratives
- MeSH terms
- Amygdala, Arousal, Auditory Perception, Emotions, Female, Humans, Individuality, Functional Laterality, Male, Memory, Middle Aged, Neuropsychological Tests, Mental Recall, Sex Characteristics, Temporal Lobe, Verbal Behavior, Visual Perception, Neurosurgical Procedures
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