Genetic recombination with newcastle disease virus, polioviruses, and influenza
Abstract
The importance of genetic studies in under-standing the nature of an organism has been repeatedly demonstrated. In the case of viruses, there is an added incentive for genetic study since some of them are unique in their dependence on RNA for the transmission of hereditary characters. Among the known RNA viruses, those which affect plants are the least amenable to genetic study for technical reasons. The newly discovered RNA phages are a most promising source of information on RNA genetics but this development lies in the future. Among the animal RNA viruses there are three on which genetic studies have been made in our laboratory: poliovirus, Newcastle disease virus (NDV) and influenza. In each of these RNA
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Recombination has been known to occur in the poliovirus genome for almost fifty years.
“Recombination has been known to occur in the poliovirus (PV) genome for almost fifty years [1,2]”
From Recombination between Poliovirus and Coxsackie A Viruses of Species C: A Model of Viral Genetic Plasticity and Emergence (2011) · cites this paper as [1]
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Natural genetic exchanges between vaccine and wild poliovirus strains in humans.
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Recombination in circulating enteroviruses
Lukashev, A. N., Lashkevich, V. A., Ivanova, O. E., Koroleva, G. A., Hinkkanen, A. E., & Ilonen, J. (2003) · Journal of Virology · doi:10.1128/jvi.77.19.10423-10431.2003 · Cited by 170 · see citing works
Genetic recombination with poliovirus type 1
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Genomic Features of Intertypic Recombinant Sabin Poliovirus Strains Excreted by Primary Vaccinees
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- Authors
- Hirst, G. K.
- Corresponding author
- Hirst, G. K.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1962-01-01
- Volume
- 27
- Issue
- 0
- Pages
- 303-309
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W2325503071
- Cited by
- 269
- References
- 1
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 6 · 2017: 4 · 2015: 3 · 2014: 8 · 2013: 2 · 2012: 6
- Type
- posted content
- Language
- en
- Open access
- closed
- Locations
- Cold Spring Harbor Symposia on Quantitative Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Keywords
- genetic recombination, Newcastle disease virus, poliovirus, influenza virus, RNA viruses, viral genetics
- MeSH terms
- Animals, Genetics, Humans, Influenza, Human, Newcastle disease virus, Orthomyxoviridae, Recombination, Genetic, RNA, RNA, Viral, Poliovirus
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