Mutations of Arabidopsis in Potential Transduction and Response Components of the Phototropic Signaling Pathway

Liscum, E.; Briggs, W. R.

doi:10.1104/pp.112.1.291

Cited by 140Light effects on plantsPlant Molecular Biology ResearchPlant Parasitism and Resistance

Mutations of Arabidopsis in Potential Transduction and Response Components of the Phototropic Signaling Pathway

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Liscum, E., Briggs, W. R.·1996·Plant Physiology

DOI 10.1104/pp.112.1.291PMC PMC157948

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Abstract

Four genetic loci were recently identified by mutations that affect phototropism in Arabidopsis thaliana (L.) Heyhn. seedlings. It was hypothesized that one of these loci, NPH1, encodes the apoprotein for a phototropic photoreceptor. All of the alleles at the other three mutant loci (nph2, nph3, and nph4) contained wild-type levels of the putative NPH1 protein and exhibited normal blue-light-dependent phosphorylation of the NPH1 protein. This indicated that the NPH2, NPH3, and NPH4 proteins likely function downstream of NPH1 photoactivation. We show here that, although the nph2, nph3, and nph4 mutants are all altered with respect to their phototropic responses, only the nph4 mutants are also altered in their gravitropic responsiveness. Thus, NPH2 and NPH3 appear to act as signal carriers in a phototropism-specific pathway, whereas NPH4 is required for both phototropism and gravitropism and thus may function directly in the differential growth response. Despite their altered phototropic responses in blue and green light as etiolated seedlings, the nph2 and nph4 mutants exhibited less dramatic mutant phenotypes as de-etiolated seedlings and when etiolated seedlings were irradiated with unilateral ultraviolet-A (UV-A) light. Examination of the phototropic responses of a mutant deficient in biologically active phytochromes, hy1–100, indicated that phytochrome transformation by UV-A light mediates an increase in phototropic responsiveness, accounting for the greater phototropic curvature of the nph2 and nph4 mutants to UV-A light than to blue light.

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Mutations in NPH3 cause Arabidopsis to lose all-intensity blue light-induced phototropism, indicating that NPH3 regulates both PHOT1-mediated phototropism under low-fluence blue light and the PHOT1- and PHOT2-mediated high-fluence blue light response.
“Mutations in NPH3 causes Arabidopsis lose all-intensity blue light-induced phototropism, indicating that NPH3 regulates both PHOT1-mediated phototropism under low-fluence blue light and the PHOT1- and PHOT2-mediated high-fluence blue light response (Liscum and Briggs, 1996; Motchoulski and Liscum, 1999).”
From The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants (2022) · cites this paper as Liscum and Briggs, 1996
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Background
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Authors: Liscum, E., & Briggs, W. R.
Affiliations: Department of Plant Biology, Carnegie Institution of Washington, 290 Panama Street, Stanford, California 94305–1297
Carnegie Institution for Science (US)
Venue: Plant Physiology
Publisher: Oxford University Press (OUP)
Published: 1996-09-01
Volume: 112
Issue: 1
Pages: 291-296
ISSN: 0032-0889 (ISSN-L)
1532-2548
DOI: 10.1104/pp.112.1.291
PMC: PMC157948
OpenAlex: W2099197358
Cited by: 140
References: 30
Citations by year: 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 5 · 2017: 7 · 2016: 1 · 2015: 3 · 2014: 6 · 2013: 2 · 2012: 6
FWCI: 9.06
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: PLANT PHYSIOLOGY (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Science Foundation (9118392)
Carnegie Institution of Washington
National Institutes of Health (1f32gm015682-01)
National Institute of General Medical Sciences (1F32GM15682)
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
Keywords: phototropism, gravitropism, NPH3, photoreceptor signaling, signal transduction, phytochrome, UVA, blue light, Arabidopsis thaliana mutants
MeSH terms: Apoproteins, Light, Phosphoproteins, Phosphorylation, Phytochrome, Ultraviolet Rays, Signal Transduction, Mutagenesis, Genes, Plant, Protein Serine-Threonine Kinases, Arabidopsis, Arabidopsis Proteins

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Mutations of Arabidopsis in Potential Transduction and Response Components of the Phototropic Signaling Pathway

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