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Cited by 320

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

The heat-stress factor HSFA6b connects ABA signaling and ABA-mediated heat responses

Open access
Huang, Ya-Chen, Niu, Chung-Yen, Yang, Chen-Ru, Jinn, Tsung-Luo·2016·Plant Physiology
DOI 10.1104/pp.16.00860
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Abstract

Heat stress response (HSR) is a conserved mechanism developed to increase the expression of heat shock proteins (HSPs) via a heat shock factor (HSF)-dependent mechanism. Signaling by the stress phytohormone abscisic acid (ABA) is involved in acquired thermotolerance as well. Analysis of Arabidopsis (Arabidopsis thaliana) microarray databases revealed that the expression of HSFA6b, a class A HSF, extensively increased with salinity, osmotic, and cold stresses, but not heat. Here, we show that HSFA6b plays a pivotal role in the response to ABA and in thermotolerance. Salt-inducible HSFA6b expression was down-regulated in ABA-insensitive and -deficient mutants; however, exogenous ABA application restored expression in ABA-deficient, but not -insensitive plants. Thus, ABA signaling is required for proper HSFA6b expression. A transcriptional activation assay of protoplasts revealed that ABA treatment and coexpression of an ABA signaling master effector, ABA-RESPONSIVE ELEMENT-BINDING PROTEIN1, could activate the HSFA6b promoter. In addition, HSFA6b directly bound to the promoter of DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN2A and enhanced its expression. Analysis of ABA responses in seed germination, cotyledon greening, and root growth as well as salt and drought tolerance in HSFA6b-null, overexpression, and dominant negative mutants revealed that HSFA6b is a positive regulator participating in ABA-mediated salt and drought resistance. Thermoprotection tests showed that HSFA6b was required for thermotolerance acquisition. Our study reveals a network in which HSFA6b operates as a downstream regulator of the ABA-mediated stress response and is required for heat stress resistance. This new ABA-signaling pathway is integrated into the complex HSR network in planta.

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Metadata

Authors
Huang, Y.-C., Niu, C.-Y., Yang, C.-R., & Jinn, T.-L.
Venue
Plant Physiology
Publisher
Oxford University Press (OUP)
Published
2016-08-04
Volume
172
Issue
2
Pages
pp.00860.2016
ISSN
  • 0032-0889 (ISSN-L)
  • 1532-2548
DOI
10.1104/pp.16.00860
OpenAlex
W2481855603
Cited by
320
References
80
FWCI
19.60
Type
journal article
Language
en
Open access
hybrid
Funders
  • National Taiwan University (103R892003,104R892003 and 105R89203)
  • Ministry of Science and Technology, Taiwan (MOST) (102-2311-B-002-031,103-2311-B-002-008 and 104-2311-B-002-007)

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